The Antiaggregative and Antiamyloidogenic Properties of Nanoparticles: A Promising Tool for the Treatment and Diagnostics of Neurodegenerative Diseases.

abstract：:Ultraviolet radiation is an environmental carcinogenic agent that enhances inflammation and immunological reactions in the exposed human skin cells leading to oxidative photoaging of the epidermal and dermal segment. In the present study, we investigated the protective role of ursolic acid (UA) against ultraviolet B (...

journal_title：Oxidative medicine and cellular longevity

authors： Samivel R,Nagarajan RP,Subramanian U,Khan AA,Masmali A,Almubrad T,Akhtar S

更新日期：2020-06-15 00:00:00

abstract：:Nitro-oxidative stress (NOS) plays a fundamental role in aging, as well as in the pathogenesis of neurodegenerative disorders, and major depression (MD). The latter is a very frequent psychiatric illness characterized by accelerated aging, neurodegeneration, high comorbidity with age-related disorders, and premature m...

journal_title：Oxidative medicine and cellular longevity

authors： Luca M,Luca A,Calandra C

更新日期：2013-01-01 00:00:00

abstract：:Stroke is a leading cause of mortality worldwide, as well as a source of long-term disabilities and huge socioeconomic costs. This study investigates the effects of resveratrol, an antioxidant supplement, on blood pressure, weight status, glucose, and lipid profile in patients who had a stroke in the last 12 months. T...

journal_title：Oxidative medicine and cellular longevity

authors： Fodor K,Tit DM,Pasca B,Bustea C,Uivarosan D,Endres L,Iovan C,Abdel-Daim MM,Bungau S

更新日期：2018-03-18 00:00:00

abstract：:Oxidative stress is involved in the development of carotid body (CB) chemosensory potentiation and systemic hypertension induced by chronic intermittent hypoxia (CIH), the main feature of obstructive sleep apnea. We tested whether peroxynitrite (ONOO(-)), a highly reactive nitrogen species, is involved in the enhanced...

journal_title：Oxidative medicine and cellular longevity

authors： Moya EA,Arias P,Varela C,Oyarce MP,Del Rio R,Iturriaga R

更新日期：2016-01-01 00:00:00

abstract：:The ability to produce cold plasma at atmospheric pressure conditions was the basis for the rapid growth of plasma-related application areas in biomedicine. Plasma comprises a multitude of active components such as charged particles, electric current, UV radiation, and reactive gas species which can act synergisticall...

journal_title：Oxidative medicine and cellular longevity

authors： Bernhardt T,Semmler ML,Schäfer M,Bekeschus S,Emmert S,Boeckmann L

更新日期：2019-09-03 00:00:00

abstract：:Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOXs) are key transmembrane proteins leading to reactive oxygen species (ROS) overproduction. However, the detailed roles of NOXs in retinal pigment epithelial (RPE) cell metabolic stress induced by Earle's balanced salt solution (EBSS) through starvation r...

journal_title：Oxidative medicine and cellular longevity

authors： Zhang Y,Ren S,Gu Y,Wang J,Liu Z,Zhang Z

更新日期：2018-07-29 00:00:00

abstract：:Quercetin is a flavonoid widely studied as a chemopreventive agent in different types of cancer. Previously, we reported that quercetin has a chemopreventive effect on the liver-induced preneoplastic lesions in rats. Here, we evaluated if quercetin was able not only to prevent but also to reverse rat liver preneoplast...

journal_title：Oxidative medicine and cellular longevity

authors： Carrasco-Torres G,Monroy-Ramírez HC,Martínez-Guerra AA,Baltiérrez-Hoyos R,Romero-Tlalolini MLÁ,Villa-Treviño S,Sánchez-Chino X,Vásquez-Garzón VR

更新日期：2017-01-01 00:00:00

abstract：:Oxidative stress plays a crucial role in the pathogenesis of acute pancreatitis (AP). Isoliquiritigenin (ISL) is a flavonoid monomer with confirmed antioxidant activity. However, the specific effects of ISL on AP have not been determined. In this study, we aimed to investigate the protective effect of ISL on AP using ...

journal_title：Oxidative medicine and cellular longevity

authors： Liu X,Zhu Q,Zhang M,Yin T,Xu R,Xiao W,Wu J,Deng B,Gao X,Gong W,Lu G,Ding Y

更新日期：2018-04-26 00:00:00

abstract：:Increasing evidence indicates that most of the tumors are sustained by a distinct population of cancer stem cells (CSCs), which are responsible for growth, metastasis, invasion, and recurrence. CSCs are typically characterized by self-renewal, the key biological process allowing continuous tumor proliferation, as well...

journal_title：Oxidative medicine and cellular longevity

authors： Dando I,Cordani M,Dalla Pozza E,Biondani G,Donadelli M,Palmieri M

更新日期：2015-01-01 00:00:00

abstract：:Although a growing body of evidence suggests that plant polyphenols can modulate human immune responses, their simultaneous action on monocyte and neutrophil oxidative burst is currently poorly understood. Based on the hypothesis that various polyphenols contained in plant extracts might affect the oxidative burst of ...

journal_title：Oxidative medicine and cellular longevity

authors： Burzynska-Pedziwiatr I,Bukowiecka-Matusiak M,Wojcik M,Machala W,Bienkiewicz M,Spolnik G,Danikiewicz W,Wozniak LA

更新日期：2014-01-01 00:00:00

abstract：:NADPH oxidase (Nox) is considered a major source of reactive oxygen species (ROS) in the heart in normal and pathological conditions. However, the role of Nox in severe acute pancreatitis- (SAP-) associated cardiac injury remains unclear. Therefore, we aim to investigate the contribution of Nox to SAP-associated cardi...

journal_title：Oxidative medicine and cellular longevity

authors： Wen Y,Liu R,Lin N,Luo H,Tang J,Huang Q,Sun H,Tang L

更新日期：2019-05-09 00:00:00

abstract：:An optimisation of extraction towards an increased antioxidant capacity and the study on the extracts' composition by HPLC-ESI-Q-TOF-MS were performed on different organs of a rarely studied plant: Rheum cordatum Losinsk (Polygonaceae) growing in Kazakhstan. More than 20 compounds from anthraquinones and phenolics wer...

journal_title：Oxidative medicine and cellular longevity

authors： Zhumashova G,Kukula-Koch W,Koch W,Baj T,Sayakova G,Shukirbekova A,Głowniak K,Sakipova Z

更新日期：2019-11-16 00:00:00

abstract：:Prostate carcinoma causes a great number of deaths every year; therefore, there is an urgent need to find new drug candidates to treat advanced prostate cancer. Isobavachalcone (IBC) is the chalcone composition of Psoralea corylifolia Linn used in traditional Chinese medicine. Although IBC demonstrates potent anticanc...

journal_title：Oxidative medicine and cellular longevity

authors： Li K,Zheng Q,Chen X,Wang Y,Wang D,Wang J

更新日期：2018-10-16 00:00:00

abstract：:The present study aims to explore the protective effect of human bone marrow mesenchymal stem cells (hBMSCs) on radiation-induced aortic injury (RIAI). hBMSCs were isolated and cultured from human bone marrow. Male C57/BL mice were irradiated with a dose of 18-Gy 6MV X-ray and randomly treated with either vehicle or h...

journal_title：Oxidative medicine and cellular longevity

authors： Shen Y,Jiang X,Meng L,Xia C,Zhang L,Xin Y

更新日期：2018-02-28 00:00:00

abstract：:Human skeletal muscle is a vital organ involved in movement and force generation. It suffers from deterioration in mass, strength, and regenerative capacity in sarcopenia. Skeletal muscle satellite cells are involved in the regeneration process in response to muscle loss. Tocotrienol, an isomer of vitamin E, was repor...

journal_title：Oxidative medicine and cellular longevity

authors： Lim JJ,Wan Zurinah WN,Mouly V,Norwahidah AK

更新日期：2019-01-10 00:00:00

abstract：:Metabolic syndrome is becoming commoner due to a rise in obesity rates among adults. Generally speaking, a person with metabolic syndrome is twice as likely to develop cardiovascular disease and five times as likely to develop diabetes as someone without metabolic syndrome. Increasing oxidative stress in metabolic syn...

journal_title：Oxidative medicine and cellular longevity

authors： Zhang P,Tian B

更新日期：2014-01-01 00:00:00

abstract：:There are several oxidative stress-related pathways interconnecting Alzheimer's disease and type II diabetes, two public health problems worldwide. Coincidences are so compelling that it is attractive to speculate they are the same disorder. However, some pathological mechanisms as observed in diabetes are not necessa...

journal_title：Oxidative medicine and cellular longevity

authors： Rosales-Corral S,Tan DX,Manchester L,Reiter RJ

更新日期：2015-01-01 00:00:00

abstract：:This study was conducted to assess the protective effect of extract of match (EM) on high-fat diet- (HFD-) induced cognitive deficits in male C57BL/6 mice. It was found that EM improved glucose tolerance status by measuring OGTT and IPGTT with HFD-induced mice. EM protected behavioral and memory dysfunction in Y-maze,...

journal_title：Oxidative medicine and cellular longevity

authors： Kim JM,Lee U,Kang JY,Park SK,Kim JC,Heo HJ

更新日期：2020-11-28 00:00:00

abstract：:Hydroquinone (HQ) is widely used in food stuffs and is an occupational and environmental pollutant. Although the hepatotoxicity of HQ has been demonstrated both in vitro and in vivo, the prevention of HQ-induced hepatotoxicity has yet to be elucidated. In this study, we focused on the intervention effect of aqueous ex...

journal_title：Oxidative medicine and cellular longevity

authors： Gao Y,Tang H,Xiong L,Zou L,Dai W,Liu H,Hu G

更新日期：2018-11-18 00:00:00

abstract：BACKGROUND:The human Circadian Locomotor Output Cycle protein Kaput (CLOCK) gene was originally discovered as a regulator of essential human daily rhythms. This seemingly innocuous gene was then found to be associated with a multitude of human malignancies, via several biochemical pathways. We aimed to further investig...

journal_title：Oxidative medicine and cellular longevity

authors： Tang X,Guo D,Lin C,Shi Z,Qian R,Fu W,Liu J,Li X,Fan L

更新日期：2015-01-01 00:00:00

abstract：:Vascular endothelial dysfunction is associated with increased mortality in patients with diabetes. Astragaloside IV (As-IV) is a bioactive saponin with therapeutic potential as an anti-inflammatory and antiendothelial dysfunction. However, the underlying mechanism for how As-IV ameliorated endothelial dysfunction is s...

journal_title：Oxidative medicine and cellular longevity

authors： Leng B,Li C,Sun Y,Zhao K,Zhang L,Lu ML,Wang HX

更新日期：2020-09-14 00:00:00

abstract：:The present study discusses about the effects of a combination of probiotics able to stimulate the immune system of patients affected by Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME). To this purpose, patients diagnosed according to Fukuda's criteria and treated with probiotics were analyzed by means of ...

journal_title：Oxidative medicine and cellular longevity

authors： Venturini L,Bacchi S,Capelli E,Lorusso L,Ricevuti G,Cusa C

更新日期：2019-11-23 00:00:00

abstract：:Oxidative stress is crucially involved in the pathogenesis of neurological diseases such as stroke and degenerative diseases. We previously demonstrated that platelet-derived growth factors (PDGFs) protected neurons from H2O2-induced oxidative stress and indicated the involvement of PI3K-Akt and MAP kinases as an unde...

journal_title：Oxidative medicine and cellular longevity

authors： Zheng LS,Ishii Y,Zhao QL,Kondo T,Sasahara M

更新日期：2013-01-01 00:00:00

abstract：:Renal ischemia-reperfusion injury (RIRI) refers to a phenomenon associated with dysfunction of the kidney and tissue damage. Unfortunately, no specific drugs have been found that effectively prevent and treat RIRI. Curcumin (Cur), a polyphenol extracted from turmeric, possesses a variety of biological activities invol...

journal_title：Oxidative medicine and cellular longevity

authors： Wang ZH,Deng LH,Chi CW,Wang H,Huang YY,Zheng Q

更新日期：2020-11-12 00:00:00

abstract：:OVE26 mice are a widely used transgenic model of early-onset type 1 diabetes. These mice overexpress calmodulin in their pancreatic β cells, develop severe diabetes within the first weeks of life, and progress to severe diabetic complications including diabetic nephropathy and diabetic cardiomyopathy (DCM). To date, d...

journal_title：Oxidative medicine and cellular longevity

authors： Tang X,Jiang S,Zhang J,Zhou S,Zheng Y

更新日期：2020-05-14 00:00:00

abstract：Objective:Oxidized cholesterol derivatives are compounds with proven atherogenic and mutagenic effects. However, little is known about the effect of oxidized plant sterol derivatives (oxyphytosterols), whose structure is similar to the one of oxycholesterols. Our previous studies indicate that they have a similar profi...

journal_title：Oxidative medicine and cellular longevity

authors： Wielkoszyński T,Zalejska-Fiolka J,Strzelczyk JK,Owczarek AJ,Cholewka A,Kokoszczyk K,Stanek A

更新日期：2020-06-08 00:00:00

abstract：:Andrographolide (Andro), a major bioactive component obtained from Andrographis paniculata Nees, has exerted wide antioxidant as well as cytoprotective properties. However, whether Andro treatment could retard the progress of diabetic cardiomyopathy (DCM) remains unknown. In this study, we evaluated the effects of And...

journal_title：Oxidative medicine and cellular longevity

authors： Liang E,Liu X,Du Z,Yang R,Zhao Y

更新日期：2018-06-25 00:00:00

abstract：:Hydrogen sulfide (H2S) is a gasotransmitter with a variety of cardiovascular protective effects. Sirtuin 3 (SIRT3) is closely related to mitochondrial function and oxidative stress. We found that NaHS increased SIRT3 expression in the preventive effect on isoproterenol- (ISO-) induced myocardial hypertrophy. We furthe...

journal_title：Oxidative medicine and cellular longevity

authors： Zhang J,Yu J,Chen Y,Liu L,Xu M,Sun L,Luo H,Wang Y,Meng G

更新日期：2018-12-17 00:00:00

abstract：:Respiratory diseases are accompanied by intensification of free radical processes at different levels of the biological body organization. Simultaneous stress and suppression of various parts of antioxidant protection lead to the development of oxidative stress (OS) and nitrosative stress (NS). The basic mechanisms of...

journal_title：Oxidative medicine and cellular longevity

authors： Soodaeva S,Kubysheva N,Klimanov I,Nikitina L,Batyrshin I

更新日期：2019-05-22 00:00:00

abstract：:Alzheimer's disease (AD) is the most common cause of dementia and a great socioeconomic burden in the aging society. Compelling evidence demonstrates that molecular change characteristics for AD, such as oxidative stress and amyloid β (Aβ) oligomerization, precede by decades the onset of clinical dementia and that the...

journal_title：Oxidative medicine and cellular longevity

authors： Wojsiat J,Zoltowska KM,Laskowska-Kaszub K,Wojda U

更新日期：2018-01-31 00:00:00