Construction and Validation of Predictive Model to Identify Critical Genes Associated with Advanced Kidney Disease.

abstract：:The yellow color of inner leaves in Chinese cabbage depends on its lutein and carotene content. To identify responsible genes for yellow pigmentation in leaves, the transcriptome profiles of white (Kenshin) and yellow leaves (Wheessen) were examined using the Br300K oligomeric chip in Chinese cabbage. In yellow leaves...

journal_title：International journal of genomics

authors： Jung HJ,Manoharan RK,Park JI,Chung MY,Lee J,Lim YP,Hur Y,Nou IS

更新日期：2014-01-01 00:00:00

abstract：:The threat of heat stress on crop production increased dramatically due to global warming leading to the rise on the demand of heat-tolerant crops and understanding their tolerance. The leguminous forage crop Guar [Cyamopsis tetragonoloba (L.) Taub] is a high-temperature tolerant plant with numerous works on its toler...

journal_title：International journal of genomics

authors： Alshameri A,Al-Qurainy F,Gaafar AR,Khan S,Nadeem M,Alansi S

更新日期：2020-06-19 00:00:00

abstract：:Puberty is a transition period where a child transforms to an adult. Puberty can be affected by various genetic factors and environmental influences. In mammals, the regulation of puberty is enhanced by the hypothalamic-pituitary-gonadal axis (HPG axis). A number of genes such as GnRH, Kiss1, and GPR54 have been repor...

journal_title：International journal of genomics

authors： Omariba G,Xiao J

更新日期：2020-05-22 00:00:00

abstract：:The Gene Ontology (GO) provides a resource for consistent annotation of genes and gene products that is extensively used by numerous large public repositories. The GO is constructed of three subontologies describing the cellular component of action, molecular function, and overall biological process of a gene or gene ...

journal_title：International journal of genomics

authors： Francis RW

更新日期：2013-01-01 00:00:00

abstract：Purpose:Next-generation sequencing (NGS) has become more accessible, leading to an increasing number of genetic studies of familial bradycardia being reported. However, most of the variants lack full evaluation. The relationship between genetic factors and bradycardia should be summarized and reevaluated. Methods:We s...

journal_title：International journal of genomics

authors： Cheng L,Li X,Zhao L,Wang Z,Zhang J,Liang Z,Wu Y

更新日期：2020-02-25 00:00:00

abstract：:Sweet sorghum (Sorghum bicolor) is one of the most important cereal crops in the world with colorful seeds. To study the diversity and cultivar-specificity of phytochemicals in sweet sorghum seeds, widely targeted metabolomics was used to analyze the metabolic profiles of the white, red, and purple seeds from three sw...

journal_title：International journal of genomics

authors： Zhou Y,Wang Z,Li Y,Li Z,Liu H,Zhou W

更新日期：2020-03-04 00:00:00

abstract：:We screened bacteria that use E2 as its sole source of carbon and energy for growth and identified them as Rhodococcus, and we named them DSSKP-R-001. For a better understanding of the metabolic potential of the strain, whole genome sequencing of Rhodococcus DSSKP-R-001 and annotation of the functional genes were perf...

journal_title：International journal of genomics

authors： Zhao H,Tian K,Qiu Q,Wang Y,Zhang H,Ma S,Jin S,Huo H

更新日期：2018-10-28 00:00:00

abstract：:The wild Rubus species R. coreanus, which is widely distributed in southwest China, shows great promise as a genetic resource for breeding. One of its outstanding properties is adaptation to high temperature and humidity. To facilitate its use in selection and breeding programs, we assembled de novo 179,738,287 R. cor...

journal_title：International journal of genomics

authors： Chen Q,Liu X,Hu Y,Sun B,Hu Y,Wang X,Tang H,Wang Y

更新日期：2018-04-01 00:00:00

abstract：:To explore heat response mechanisms of mircoRNAs (miRNAs) in rice post-meiosis panicle, microarray analysis was performed on RNA isolated from rice post-meiosis panicles which were treated at 40°C for 0 min, 10 min, 20 min, 60 min, and 2 h. By integrating paired differentially expressed (DE) miRNAs and mRNA expression...

journal_title：International journal of genomics

authors： Peng Y,Zhang X,Liu Y,Chen X

更新日期：2020-09-17 00:00:00

abstract：:Rheumatoid arthritis (RA) is an autoimmune disease characterized by the presence of antibodies against cyclic citrullinated peptide (anti-CCP), a consequence of the breakdown of immune tolerance. The lymphoid tyrosine phosphatase (Lyp) protein has significant effects on maintenance of peripheral immune tolerance. Two ...

journal_title：International journal of genomics

authors： Ruiz-Noa Y,Padilla-Gutiérrez JR,Hernández-Bello J,Palafox-Sánchez CA,Valle Y,Oregón-Romero E,Pereira-Suárez AL,Bernard-Medina AG,Muñoz-Valle JF

更新日期：2017-01-01 00:00:00

abstract：:Pseudomonas aeruginosa PGPR2 is a mung bean rhizosphere strain that produces secondary metabolites and hydrolytic enzymes contributing to excellent antifungal activity against Macrophomina phaseolina, one of the prevalent fungal pathogens of mung bean. Genome sequencing was performed using the Ion Torrent Personal Gen...

journal_title：International journal of genomics

authors： Illakkiam D,Shankar M,Ponraj P,Rajendhran J,Gunasekaran P

更新日期：2014-01-01 00:00:00

abstract：:Calmodulin II (CALM2) gene polymorphism might be responsible for the variation in the left ventricular mass amongst healthy individuals. The aim was to evaluate the correlation between left ventricular mass (LVM) and g.474955027G>A (rs7565161) polymorphism adjacent to the CALM2 gene. Healthy Polish newborns (n = 206) ...

journal_title：International journal of genomics

authors： Gorący I,Gorący J,Skonieczna-Żydecka K,Kaczmarczyk M,Dawid G,Ciechanowicz A

更新日期：2013-01-01 00:00:00

abstract：:Rice grain shape and nutritional quality traits have high economic value for commercial production of rice and largely determine the market price, besides influencing the global food demand for high-quality rice. In order to understand the genetic components of grain appearance traits in paddy, brown, and head rice, 1...

journal_title：International journal of genomics

authors： Bazrkar-Khatibani L,Fakheri BA,Hosseini-Chaleshtori M,Mahender A,Mahdinejad N,Ali J

更新日期：2019-02-25 00:00:00

abstract：:Arabidopsis thaliana (L.) Heynh. is a model organism of plant molecular biology. More than 1,700 whole genome sequences have been sequenced, but no Korean isolate genomes have been sequenced thus far despite the fact that many A. thaliana isolated in Japan and China have been sequenced. To understand the genetic backg...

journal_title：International journal of genomics

authors： Park J,Xi H,Kim Y

更新日期：2020-09-05 00:00:00

abstract：:To better understand the molecular functions of the master stress-response regulator AtfA in Aspergillus nidulans, transcriptomic analyses of the atfA null mutant and the appropriate control strains exposed to menadione sodium bisulfite- (MSB-), t-butylhydroperoxide- and diamide-induced oxidative stresses were perform...

journal_title：International journal of genomics

authors： Orosz E,Antal K,Gazdag Z,Szabó Z,Han KH,Yu JH,Pócsi I,Emri T

更新日期：2017-01-01 00:00:00

abstract：:Severe gastroenteritis and foodborne illness caused by Noroviruses (NoVs) during the winter are a worldwide phenomenon. Vulnerable populations including young children and elderly and immunocompromised people often require hospitalization and may die. However, no efficient vaccine for NoVs exists because of their vari...

journal_title：International journal of genomics

authors： Huang CC,Tang CY

更新日期：2013-01-01 00:00:00

abstract：:Determining protein-protein interaction (PPI) in biological systems is of considerable importance, and prediction of PPI has become a popular research area. Although different classifiers have been developed for PPI prediction, no single classifier seems to be able to predict PPI with high confidence. We postulated th...

journal_title：International journal of genomics

authors： Yao J,Guo H,Yang X

更新日期：2015-01-01 00:00:00

abstract：:Cancer is a multistep process characterized by various and different genetic lesions which cause the transformation of normal cells into tumor cells. To preserve the genomic integrity, eukaryotic cells need a complex DNA damage/repair response network of signaling pathways, involving many proteins, able to induce cell...

journal_title：International journal of genomics

authors： Tessitore A,Cicciarelli G,Del Vecchio F,Gaggiano A,Verzella D,Fischietti M,Vecchiotti D,Capece D,Zazzeroni F,Alesse E

更新日期：2014-01-01 00:00:00

abstract：:Simple sequence repeats (SSRs) are among the most important markers for population analysis and have been widely used in plant genetic mapping and molecular breeding. Expressed sequence tag-SSR (EST-SSR) markers, located in the coding regions, are potentially more efficient for QTL mapping, gene targeting, and marker-...

journal_title：International journal of genomics

authors： Ding Q,Li J,Wang F,Zhang Y,Li H,Zhang J,Gao J

更新日期：2015-01-01 00:00:00

abstract：:Osteoporosis is a serious public health issue, which is mostly characterized by low bone mineral density (BMD). To search for additional genetic susceptibility loci underlying BMD variation, an effective strategy is to focus on testing of specific variants with high potential of functional effects. Single nucleotide p...

journal_title：International journal of genomics

authors： Qiu C,Shen H,Fu X,Xu C,Deng H

更新日期：2018-08-07 00:00:00

abstract：:A population of 146 RILs (Recombinant Inbred Line) was derived from the cross between a cold-sensitive cultivated Solanum lycopersicum L. XF98-7 and a cold-tolerant wild Solanum pimpinellifolium LA2184. Relative germination ratio (RGR) and chilling index (CI) were used to evaluate the cold tolerance of the parental li...

journal_title：International journal of genomics

authors： Liu Y,Zhou T,Ge H,Pang W,Gao L,Ren L,Chen H

更新日期：2016-01-01 00:00:00

abstract：:Background and Objectives. Chronic obstructive pulmonary disease (COPD) is a complex disease characterized by airflow limitation. Although airway inflammation and oxidative stress are known to be important in the pathogenesis of COPD, the mechanism underlying airflow obstruction is not fully understood. Gene expressio...

journal_title：International journal of genomics

authors： Kim WJ,Lim JH,Lee JS,Lee SD,Kim JH,Oh YM

更新日期：2015-01-01 00:00:00

abstract：Background:Breast cancer development and progression involve both germline and somatic mutations. High-throughput genotyping and next-generation sequencing technologies have enabled discovery of genetic risk variants and acquired somatic mutations driving the disease. However, the possible oncogenic interactions betwee...

journal_title：International journal of genomics

authors： Wu J,Mamidi TKK,Zhang L,Hicks C

更新日期：2020-07-06 00:00:00

abstract：:The genera Actinobacillus, Haemophilus, and Pasteurella exhibit extensive polyphyletic branching in phylogenetic trees and do not represent coherent clusters of species. In this study, we have utilized molecular signatures identified through comparative genomic analyses in conjunction with genome based and multilocus ...

journal_title：International journal of genomics

authors： Naushad S,Adeolu M,Goel N,Khadka B,Al-Dahwi A,Gupta RS

更新日期：2015-01-01 00:00:00

abstract：:Paulownia witches' broom caused by phytoplasma infection affects the production of Paulownia trees worldwide. Emerging evidence showed that long noncoding RNAs (lncRNA) play a protagonist role in regulating the expression of genes in plants. So far, the identification of lncRNAs has been limited to a few model plant s...

journal_title：International journal of genomics

authors： Fan G,Cao Y,Wang Z

更新日期：2018-02-21 00:00:00

abstract：:The HIV-1 virus (human immunodeficiency virus) affects 36.9 million people worldwide, with approximately 900000 deaths in 2017. The virus carrier can develop severe immunodeficiency since CD4+ T lymphocytes are the main target, leading to acquired immunodeficiency syndrome (AIDS). Despite advances in pharmacological t...

journal_title：International journal of genomics

authors： Sanches-da-Silva GN,Medeiros LFS,Lima FM

更新日期：2019-08-21 00:00:00

abstract：:The Chinese Kunming (KM) mouse is a widely used outbred mouse stock in China. However, its genetic structure remains unclear. In this study, we sequenced the genome of the C57BL/6J-Chr1KM (B6-Chr1KM) strain, the chromosome 1 (Chr 1) of which was derived from one KM mouse. With 36.6× average coverage of the entire geno...

journal_title：International journal of genomics

authors： Xu F,Chao T,Zhang Y,Hu S,Zhou Y,Xu H,Xiao J,Li K

更新日期：2017-01-01 00:00:00

abstract：:Apicomplexan protist parasites utilize host sugars transported into the parasite by sugar transporter proteins for use as an energy source. We performed a phylum-wide phylogenetic analysis of the apicomplexan sugar transporter repertoire. Phylogenetic analyses revealed six major subfamilies of apicomplexan sugar trans...

journal_title：International journal of genomics

authors： Mahmud O,Kissinger JC

更新日期：2017-01-01 00:00:00

abstract：:Paeonia lactiflora is a herbaceous flower in the family Paeoniaceae with both hypocotyl and epicotyl dormant seeds. We used high-throughput transcriptome sequencing on two different developmental stages of P. lactiflora seeds to identify seed dormancy and germination-related genes. We performed de novo assembly and an...

journal_title：International journal of genomics

authors： Ma Y,Cui J,Lu X,Zhang L,Chen Z,Fei R,Sun X

更新日期：2017-01-01 00:00:00

abstract：:Taxol is one of the most potent and effective anticancer drugs and is originally isolated from Taxus species. To investigate the specific regulatory mechanisms of taxol synthesis in Taxus wallichiana var. mairei, RNA-seq was conducted to reveal the differences in transcriptional levels between wild type (WT) and "Jinx...

journal_title：International journal of genomics

authors： Wang T,Chen Y,Zhuang W,Zhang F,Shu X,Wang Z,Yang Q

更新日期：2019-05-02 00:00:00