Abstract:
:Background Among breast cancer survivors, detecting a breast cancer when it is asymptomatic (rather than symptomatic) improves survival; thus, imaging surveillance in these patients is warranted. Digital breast tomosynthesis (DBT) is used for screening, but data on DBT for surveillance in this high-risk population are limited. Purpose To determine whether DBT leads to improved screening performance metrics when compared with two-dimensional digital mammography among breast cancer survivors. Materials and Methods In this study, screening mammograms obtained in breast cancer survivors before and after DBT implementation were retrospectively reviewed (March 2008-February 2011 for the digital mammography group; January 2013-December 2017 for the DBT group). Mammograms were interpreted by breast imaging radiologists with the assistance of computer-aided detection. Performance metrics and tumor characteristics between the groups were compared using multivariable logistic regression models. Results The digital mammography and DBT groups were composed of 9019 and 22 887 mammographic examinations, respectively, in 8170 women (mean age, 62 years ± 12 [standard deviation]). In the DBT group, the abnormal interpretation rate was lower (5.8% [1331 of 22 887 examinations] vs 6.2% [563 of 9019 examinations]; odds ratio [OR], 0.80; 95% CI: 0.71, 0.91; P = .001) and specificity was higher (95.0% [21 502 of 22 644 examinations] vs 94.7% [8424 of 8891 examinations]; OR, 1.23; 95% CI: 1.07, 1.41; P = .003) than in the digital mammography group. The cancer detection rates did not differ (8.3 per 1000 examinations with DBT vs 10.6 with digital mammography; OR, 0.76; 95% CI: 0.57, 1.02; P = .07). The proportions of screening-detected invasive cancers, versus in situ cancers, were similar (74% [140 of 189 cancers] in the DBT group vs 72% [69 of 96 cancers] in the digital mammography group; P = .69). Of 86 interval cancers, 58% (50 of 86 cancers) manifested with symptoms, and 33% (28 of 86 cancers) were detected at screening MRI. Conclusion Among breast cancer survivors, screening with digital breast tomosynthesis led to fewer false-positive results and higher specificity but did not affect cancer detection. © RSNA, 2020 Online supplemental material is available for this article. See also the editorial by Hooley and Butler in this issue.
journal_name
Radiologyjournal_title
Radiologyauthors
Bahl M,Mercaldo S,McCarthy AM,Lehman CDdoi
10.1148/radiol.2020201854subject
Has Abstractpub_date
2021-02-01 00:00:00pages
308-316issue
2eissn
0033-8419issn
1527-1315journal_volume
298pub_type
杂志文章相关文献
RADIOLOGY文献大全abstract::The results of percutaneous drainage of abdominal abscesses in 136 patients are analyzed, revealing a failure rate of 23% (31 patients). The mortality rate was 1.4% (two patients); the rate of serious complications was 5% (seven patients). Failure rate was lowest in critically ill patients having palliative drainage o...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.159.2.2421370
更新日期:1986-05-01 00:00:00
abstract::A linear-array, silicon pixel detector, capable of counting single photons, was applied to mammography by using a synchrotron radiation beam. Images were obtained of both a mammographic phantom and a breast-tissue sample. The phantom image was acquired with a mean glandular dose of 0.32 mGy. This detector combined wit...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.208.3.9722850
更新日期:1998-09-01 00:00:00
abstract::Background Identification of large vessel occlusion (LVO) is critical to the management of acute ischemic stroke and prerequisite to endovascular therapy in recent trials. Increasing volumes and data complexity compel the development of fast, reliable, and automated tools for LVO detection to facilitate acute imaging ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2021202734
更新日期:2021-01-12 00:00:00
abstract::The rationale for prebiopsy and preoperative irradiation in a multimodal approach to treatment of osteosarcoma is presented. Six patients with osteosarcoma underwent preoperative irradiation, amputation, and elective chemotherapy. Five of these also received prebiopsy irradiation: three survive without metastases at 2...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/125.2.497
更新日期:1977-11-01 00:00:00
abstract::A metastatic tumor in the right ventricle was clearly visualized using two-dimensional echocardiography. The location, size, and mobility of the tumor were easily demonstrated. Two-dimensional echocardiography is superior to M-mode echocardiography in such cases. ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/129.2.471
更新日期:1978-11-01 00:00:00
abstract:PURPOSE:To evaluate the sensitivity and specificity of biphasic computed tomography (CT) with mesenteric CT angiography in the diagnosis of acute mesenteric ischemia (AMI). MATERIALS AND METHODS:Sixty-two patients with clinically suspected AMI underwent prospective imaging with biphasic multi-detector row CT. Mesenter...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2291020991
更新日期:2003-10-01 00:00:00
abstract::Effect of noise reduction filters on chest computed tomographic (CT) images acquired with 50% radiation dose reduction was evaluated. Two sets of images were acquired with multi-detector row CT at standard (220-280 mA) and 50% reduced (110-140 mA) tube current at the level of the carina. After postprocessing with six ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2281020606
更新日期:2003-07-01 00:00:00
abstract::Although some cerebral vascular malformations are angiographically occult, the correct diagnosis may be suggested by their appearance on computed tomography (CT). The authors advise caution in assuming that angiographically avascular lesions which show contrast enhancement on CT represent neoplasms rather than vascula...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/123.3.649
更新日期:1977-06-01 00:00:00
abstract:PURPOSE:To prospectively compare the accuracy of fluorine 18 fluorodeoxyglucose (FDG) positron emission tomography (PET) and computed tomography (CT) for detection of primary tumor and metastasis to individual lymph node groups and for nodal staging. MATERIALS AND METHODS:From February 2000 to July 2001, 81 patients w...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2281020423
更新日期:2003-06-01 00:00:00
abstract::The histological nature and angiographic characteristics of two cases of Castleman tumor support the concept that these tumors are hamartomatous. On angiography, both tumors exhibited a dense and homogeneous blush in the later phase. In one, in the mediastinum, hypertrophied branches of the bronchial artery gave rise ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/130.2.311
更新日期:1979-02-01 00:00:00
abstract::The variety of cervical lymphadenectomy and neck reconstructive procedures that have been developed in the past 20 years has led to confusion about nomenclature in the literature. In addition, some of these operations result in gross alteration of the normal anatomy. The authors review the present classification syste...
journal_title:Radiology
pub_type: 杂志文章,评审
doi:10.1148/radiology.187.3.8497600
更新日期:1993-06-01 00:00:00
abstract:PURPOSE:To outline a quality assessment method with peer review for magnetic resonance (MR) imaging. MATERIALS AND METHODS:Thirty-three providers in the Philadelphia area were rated on a random sample of 132 brain, 124 cervical spine, and 113 lower extremity MR imaging examinations performed during 1990. Blinded peer ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.196.1.7784570
更新日期:1995-07-01 00:00:00
abstract::A reciprocating Bucky design for serial film changers is described. It is simple to construct. Inexpensive, and enhances radiograph resolution by eliminating grid lines. ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/125.1.250
更新日期:1977-10-01 00:00:00
abstract::An international working group has modified the Atlanta classification for acute pancreatitis to update the terminology and provide simple functional clinical and morphologic classifications. The modifications (a) address the clinical course and severity of disease, (b) divide acute pancreatitis into interstitial edem...
journal_title:Radiology
pub_type: 杂志文章,评审
doi:10.1148/radiol.11110947
更新日期:2012-03-01 00:00:00
abstract::Twenty-one bone marrow transplantation (BMT) patients were studied prospectively to determine the prevalence of sonographic hepatobiliary abnormalities and to determine if these abnormalities were associated with hepatic venocclusive disease (VOD). Baseline US was performed in all patients prior to chemoradiation ther...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.184.3.1509050
更新日期:1992-09-01 00:00:00
abstract:PURPOSE:To investigate whether ultrasonographic (US) features of thyroid nodules are associated with tumor recurrence in classic papillary thyroid carcinoma (PTC). MATERIALS AND METHODS:This retrospective study was approved by the Institutional Review Board, and the need to obtain informed consent was waived. A total ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2015142470
更新日期:2015-11-01 00:00:00
abstract::Renal dynamic computed tomographic (CT) data for 16 patients with unilateral renal artery stenosis were compared with those for 12 control subjects. Three patterns of perfusion were distinguished in stenotic kidneys: pattern A, symmetric time-attenuation curves; pattern B, asymmetric time-attenuation curve with simila...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2211001558
更新日期:2001-10-01 00:00:00
abstract::Persistent bile leaks after liver transplantation were successfully treated in three patients with percutaneous or surgical drainage of bilomas and endoscopic retrograde ampullary sphincterotomy. In all three patients, biliary anastomoses were achieved by means of choledochocholedochostomies, with a T-tube stent in th...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.179.3.2027980
更新日期:1991-06-01 00:00:00
abstract:PURPOSE:To investigate the relationship of spinal osteophytes to vertebral bone mineral density (BMD) and to spinal fracture. MATERIALS AND METHODS:This relationship was investigated in 203 men. Integral BMD was measured with dual x-ray absorptiometry, and both cortical and trabecular BMD were measured with quantitati...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.189.2.8210380
更新日期:1993-11-01 00:00:00
abstract::Magnetic resonance (MR) imaging was performed in 17 patients, 11-84 years of age, referred for evaluation of possible osteomyelitis involving the appendicular skeleton. MR imaging permitted successful identification of osteomyelitis in ten patients (four acute, two subacute with Brodie abscess, two chronic, and two ac...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.166.1.3336680
更新日期:1988-01-01 00:00:00
abstract:PURPOSE:To determine whether the combination of CT during arterial portography (CTAP) and CT hepatic arteriography (CTHA) provides an added benefit to triple-phase helical CT (THCT) alone in the preoperative evaluation of hepatocellular carcinoma (HCC). MATERIALS AND METHODS:Fifty-two consecutive patients with patholo...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.215.2.r00ma30373
更新日期:2000-05-01 00:00:00
abstract::Transducer side lobes consist of multiple low-intensity sound beams located outside of the main ultrasound beam. Although the echoes generated by side lobes originate outside of the main beam, they appear as specular or diffuse artifactual echoes within the beam. They are visible with both static and real-time equipme...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.145.3.7146410
更新日期:1982-12-01 00:00:00
abstract:PURPOSE:To measure the radiologic characteristics of subtle lung nodules and develop nodule phantoms that simulate these characteristics. MATERIALS AND METHODS:From a database of chest radiographs, 16 radiographs that showed confirmed subtle lung nodules were selected. The optical density values surrounding each nodul...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.202.1.8988200
更新日期:1997-01-01 00:00:00
abstract::Abdominal computed tomography (CT) scans of 55 patients who had ingested Gastrografin (meglumine diatrizoate and diatrizoate sodium) diluted to 2% with tap water and flavored with a commercial fruit juice base were reviewed. Twenty patients (36%) demonstrated intraluminal precipitation of Gastrografin shown by focal a...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.158.1.3940390
更新日期:1986-01-01 00:00:00
abstract::Purpose To reduce radiotracer requirements for amyloid PET/MRI without sacrificing diagnostic quality by using deep learning methods. Materials and Methods Forty data sets from 39 patients (mean age ± standard deviation [SD], 67 years ± 8), including 16 male patients and 23 female patients (mean age, 66 years ± 6 and ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2018180940
更新日期:2019-03-01 00:00:00
abstract::Congenital arteriovenous malformations (AVMs) involving the pelvis or an extremity were occluded in 16 symptomatic patients, who subsequently underwent tailored embolotherapy. An additional 11 patients did not undergo embolization due to unfavorable vascular anatomy or lack of significant symptoms. Permanent occlusive...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.169.2.3175000
更新日期:1988-11-01 00:00:00
abstract:PURPOSE:To prospectively evaluate the effect of experience with coronary computed tomographic (CT) angiography on the capability to detect coronary stenoses of 50% or more. MATERIALS AND METHODS:The institutional review board approved the study protocol. All patients gave consent to undergo CT angiography before conve...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2512080384
更新日期:2009-05-01 00:00:00
abstract:PURPOSE:To analyze the clinical outcomes of chemoembolization for solitary caudate lobe hepatocellular carcinoma (HCC) found at initial presentation. MATERIALS AND METHODS:This retrospective study was approved by the institutional review board; the requirement for informed patient consent was waived. From July 1998 to...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.10100105
更新日期:2010-10-01 00:00:00
abstract:PURPOSE:To evaluate prospectively bolus tracking to time hepatic arterial phase (HAP) imaging of hypervascular hepatocellular carcinomas (HCCs) with a 40-detector computed tomographic (CT) scanner. MATERIALS AND METHODS:This study received institutional review board approval; informed consent was obtained. The study i...
journal_title:Radiology
pub_type: 杂志文章,随机对照试验
doi:10.1148/radiol.2431060069
更新日期:2007-04-01 00:00:00
abstract:PURPOSE:To evaluate the effectiveness of noninvasive magnetic resonance (MR) imaging-guided focused ultrasonographic (US) ablation of breast carcinomas. MATERIALS AND METHODS:Before undergoing tumor resection, 12 patients with invasive breast carcinomas were treated with MR imaging-guided focused US ablation consistin...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2281012163
更新日期:2003-06-01 00:00:00