Abstract:
:Abdominal computed tomography (CT) scans of 55 patients who had ingested Gastrografin (meglumine diatrizoate and diatrizoate sodium) diluted to 2% with tap water and flavored with a commercial fruit juice base were reviewed. Twenty patients (36%) demonstrated intraluminal precipitation of Gastrografin shown by focal areas of markedly increased attenuation within the gastric lumen or trapped within gastric folds. Beam-hardening artifact produced by precipitation was observed, which limited the diagnostic value of some examinations. In vitro CT scans of the same Gastrografin solution titrated with hydrochloric acid or sodium hydroxide showed that by raising the pH of the solution, precipitation was virtually eliminated. Fifty-one CT scans of the abdomen using a buffered Gastrografin solution demonstrated precipitation in only five patients. Properly buffered dilute oral Gastrografin solutions should significantly decrease the prevalence of precipitation during abdominal CT examinations.
journal_name
Radiologyjournal_title
Radiologyauthors
Ball DS,Radecki PD,Friedman AC,Caroline DF,Mayer DPdoi
10.1148/radiology.158.1.3940390subject
Has Abstractpub_date
1986-01-01 00:00:00pages
258-60issue
1eissn
0033-8419issn
1527-1315journal_volume
158pub_type
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