Abstract：
:The objective of this study was to investigate the association between red blood cell (RBC) transfusion and hematocrit values with outcomes in infants undergoing Norwood operation. This study included infants ≤2 months of age who underwent Norwood operation with either a modified Blalock-Taussig shunt or a right ventricle-pulmonary artery shunt. Demographics, preoperative, operative, daily laboratory data, and postoperative variables were collected. The primary outcome measures evaluated included mortality, ICU length of stay, length of mechanical ventilation, and days to chest closure. The secondary outcome measures evaluated included lactate levels, estimated glomerular filtration rate, and inotrope score in the first 14 days after heart operation. Cox proportional hazard models were fitted to study the probability of study outcomes as a function of hematocrit values and RBC transfusions after operation. Eighty-nine patients qualified for inclusion. With a median hematocrit of 46 (IQR 44, 49), and a median RBC transfusion of 92 ml/kg (IQR 31, 384) in the first 14 days after operation, 81 (91 %) patients received RBC transfusions. A multivariable analysis adjusted for risk factors, including the age, weight, prematurity, cardiopulmonary bypass and cross-clamp time, and postoperative need for nitric oxide and dialysis, demonstrated no association between hematocrit and RBC transfusion with majority of study outcomes. This single-center study found that higher hematocrit values and increasing RBC transfusions are not associated with improved outcomes in infants undergoing Norwood operation.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Gupta P,King C,Benjamin L,Goodhart T,Robertson MJ,Gossett JM,Pesek GA,DasGupta Rdoi
10.1007/s00246-015-1147-zsubject
Has Abstractpub_date
2015-08-01 00:00:00pages
1212-8issue
6eissn
0172-0643issn
1432-1971journal_volume
36pub_type
杂志文章abstract：:In case of progressive cyanosis after modified Fontan procedure, intrahepatic shunting should be considered. Ligation of the hepatic vein is safe and effective in managing this condition, and it is important to ensure that the pressure difference between superior vena cava and the portal vein system remains minimal af...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900505
更新日期：1999-11-01 00:00:00
abstract：:We report a rare case of tetralogy of Fallot with total anomalous pulmonary venous return, left heart hypoplasia, right lung hypoplasia, and left ocular-mandibular synchinesia (Marcus-Gunn phenomenon), correctly diagnosed by cardiovascular magnetic resonance imaging and successfully operated by modified Glenn anastomo...
journal_title：Pediatric cardiology
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doi：10.1007/s00246-004-0769-3
更新日期：2005-07-01 00:00:00
abstract：:This study was conducted to determine the efficacy of procainamide therapy for rapid rate control of postoperative junctional tachycardia (JT). Postoperative JT is one of the most difficult forms of tachycardia to manage. Reported success with a variety of treatments of JT in infants and children has been inconsistent...
journal_title：Pediatric cardiology
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doi：10.1007/s002469910018
更新日期：2000-03-01 00:00:00
abstract：:Myocardial blood flow (MBF) was investigated in children (14.2 +/- 5.01 years) with "resolved" coronary involvement after the onset of Kawasaki disease and angiographically normal epicardial coronary arteries. Ten asymptomatic children with a history of Kawasaki disease had electrocardiography, echocardiography, and p...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-003-0472-9
更新日期：2004-03-01 00:00:00
abstract：:Long-term prostaglandin use is commonly associated with side effects such as cortical proliferation of the bones, hypertrophic pyloric stenosis, and soft tissue swelling of the extremities. We report a neonate with critical coarctation of the aorta, who developed second and third degree atrioventricular blocks associa...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-017-1633-6
更新日期：2017-10-01 00:00:00
abstract：:This study aimed to assess the technical aspects of atrial septal defect (ASD) closure using the Amplatzer septal occluder (ASO) and the Gore Helex septal occluder (GHSO) for infants weighing less than 8 kg and to determine the safety, effectiveness, and near-to-intermediate-term outcome of the closure. The Mid-Atlant...
journal_title：Pediatric cardiology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00246-014-0905-7
更新日期：2014-10-01 00:00:00
abstract：:In other cardiomyopathies, cardiac magnetic resonance imaging (CMR)-derived myocardial delayed enhancement (MDE), a marker of myocardial fibrosis, is a risk factor for sudden cardiac death (SCD). In Duchenne muscular dystrophy (DMD), the prognostic value of MDE for ventricular arrhythmias and death is unknown. This st...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-014-0929-z
更新日期：2014-10-01 00:00:00
abstract：:Five patients with ventricular inversion, corrected transposition of the great arteries, and atresia of the left-sided atrioventricular (tricuspid) valve have been observed. Three patients died in infancy, two had large interatrial communications, one with an early stage of arterial-type hypertensive pulmonary vascula...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02310996
更新日期：1986-01-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-019-02106-2
更新日期：2019-06-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-002-0352-8
更新日期：2003-07-01 00:00:00
abstract：:During the development of so-called aneurysmal transformation of perimembranous ventricular septal defects (pmVSD), tricuspid valve (TV) morphology and function may be altered resulting in left ventricular (LV) to right atrial (RA) shunting. The feasibility and outcome of interventional closure of these pmVSD has not ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-015-1170-0
更新日期：2015-10-01 00:00:00
abstract：:Embryonic development is a tightly regulated process, and many families of genes functions to provide a regulatory genetic network to achieve such a program. The homeobox genes are an extensive family that encodes transcription factors with a characteristic 60-amino acid homeodomain. Mutations in these genes or in the...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0179-x
更新日期：2012-08-01 00:00:00
abstract：:Previous studies have evaluated left ventricular dimensions in children using two-dimensional echocardiography, but there is little information on gender differences and on the longitudinal development of the dimensions of the left ventricle. Our objective was to assess, by two-dimensional echocardiography, the normal...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02505207
更新日期：1996-05-01 00:00:00
abstract：:We present a neonatal case with intractable atrial flutter that did not respond to digitalization and electrical cardioversion. Intravenous flecainide administration completely resolved the atrial flutter. Proarrhythmic effects were not induced by flecainide administration. Although the efficacy of flecainide for atri...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-003-0226-8
更新日期：2004-03-01 00:00:00
abstract：:M-mode and 2-dimensional (2D) echocardiographic imaging are routinely used to quantify left-ventricular (LV) size and function in pediatric patients with dilated cardiomyopathy (DCM). The reproducibility of and correlation between these techniques are unknown. This analysis sought to compare interreader, intrareader, ...
journal_title：Pediatric cardiology
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1007/s00246-013-0835-9
更新日期：2014-04-01 00:00:00
abstract：:To assess the prevalence, history, and treatment of arrhythmias, in particular preexcitation and Wolff-Parkinson-White (WPW) syndrome, in patients with Ebstein anomaly (EA) during childhood and adolescence, we performed a multicenter retrospective study of all consecutive live-born patients with EA, diagnosed, and fol...
journal_title：Pediatric cardiology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00246-009-9590-3
更新日期：2010-02-01 00:00:00
abstract：:Although the Fontan operation can improve outcomes, surviving patients still face Fontan-associated liver disease (FALD). The aim of this study was to determine the associated factors of FALD in relation to ultrasound liver elastography. A cross-sectional study was conducted for all patients on whom an ultrasound uppe...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-020-02422-y
更新日期：2020-12-01 00:00:00
abstract：:After surgical repair of an aortic coarctation a term infant presented with severe pulmonary hypertension and cyanosis unresponsive to treatment including extracorporeal membrane oxygenation. The atypical clinical course became apparent once the accompanying diagnosis of congenital alveolar capillary dysplasia with mi...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-007-9063-5
更新日期：2008-01-01 00:00:00
abstract：:Two children with acute symptomatic pericardial effusion had unusual echocardiographic findings. In each case, the pericardial effusion was hemorrhagic. Echocardiography displayed numerous linear bands coursing across the pericardial space. Recognition of this characteristic image may predict that an acute effusion is...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00817614
更新日期：1994-03-01 00:00:00
abstract：:The prevalence of asymptomatic cardiac valve anomalies was determined in 82 patients (69 females and 13 males) diagnosed as having idiopathic scoliosis and scheduled for corrective surgery (mean age at surgery 16.3 years). The preoperative study in each patient included echocardiography and ultrasound Doppler. Twenty-...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-002-1443-2
更新日期：2002-07-01 00:00:00
abstract：:To determine the influence of heart rate (HR) on systolic time intervals (STI) in neonates, serial measurements of right ventricular (RVSTI) and left ventricular systolic time intervals (LVSTI) were made on 30 healthy term newborn infants at age 4-8 h, 24-30 h, eight days, and four weeks. STI was related to HR and age...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02336549
更新日期：1985-01-01 00:00:00
abstract：:Recurrent congestive heart failure (CHF) attributable to myocarditis is a seldom-discussed entity in the scientific literature. This report describes the case of an 8-year-old girl who had three clinically identical episodes of CHF, beginning at the age of 5 years, with each episode preceded by a viral prodrome. The c...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-011-0109-3
更新日期：2012-01-01 00:00:00
abstract：:A 5-year-old child with a Fontan circulation presented with acquired left pulmonary vein occlusion related to a previous surgical repair. We managed this lesion using a hybrid technique to perforate, dilate and stent the obstructed vessel. This approach should be considered when percutaneous access to the pulmonary ve...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-016-1376-9
更新日期：2016-06-01 00:00:00
abstract：:Branch pulmonary artery stenosis (BPAS) in the setting of systemic-pulmonary artery shunts (SPS) may result in significant sequelae. Limited information exists regarding the safety and efficacy of pulmonary artery balloon angioplasty and stent implantation via SPS in neonates and infants. This study aimed to examine t...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0657-9
更新日期：2013-08-01 00:00:00
abstract：:A blood pump specifically designed to augment flow from the great veins through the lungs would ameliorate the poor physiology of the failing univentricular circulation and result in a paradigm shift in the treatment strategy for Fontan patients. This study is the first to examine mechanical cavopulmonary assistance w...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0649-9
更新日期：2013-08-01 00:00:00
abstract：:All 91,823 children born in 1980 in Bohemia (population 6.314 million; area 52,478 square kilometers) were examined at least four times during infancy and at the age of three and four years. All children who died were autopsied and those with heart disease were selected. A total of 779 children (8.223/1000 live births...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/BF02083294
更新日期：1989-10-01 00:00:00
abstract：:Horseshoe lung is a rare malformation that is often associated with lung hypoplasia and/or vascular anomalies. We describe a 10-year-old girl with horseshoe lung and unique left pulmonary vein. This is the first reported case with this vascular feature. The patient presented with signs and symptoms of severe pulmonary...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-010-9735-4
更新日期：2010-08-01 00:00:00
abstract：:Subtotal cor triatriatum sinister (partially divided left atrium) is characterized by a membrane dividing the left atrium into two portions: a dorsal accessory proximal chamber that receives part of the pulmonary venous return and a small restrictive defect in the membrane that obstructs blood flow from the accessory ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-008-9205-4
更新日期：2008-07-01 00:00:00
abstract：:Azygos continuation of inferior venacava (IVC) is well known in association with interrupted IVC. We report azygos connection of uninterrupted IVC in a young child with complex univentricular heart. This peculiar anatomy was made suitable for univentricular repair by combining percutaneous device closure of prehepatic...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-010-9802-x
更新日期：2011-01-01 00:00:00
abstract：:A 10-month-old boy was referred for tachypnea and heart murmur. An echocardiogram showed unexplained left heart dilation without evidence of an intracardiac shunt. A 64-slice computed tomographic contrast-enhanced angiography showed a large tortuous anomalous artery arising from the descending thoracic aorta and suppl...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-008-9287-z
更新日期：2009-01-01 00:00:00
