Abstract:
:Animal production has a key role in global economic development and food security. Ticks, specifically Rhipicephalus microplus cause substantial economic and health impacts on more than eighty percent of the world cattle population. Though synthetic acaricides play a major role in tick management, their injudicious usage has caused environmental pollution and also promote the establishment of multi-acaricide resistant tick populations which is a matter of great concern. To provide an effective tool for controlling these resistant ticks, the present work was aimed to develop safe and inexpensive antitick natural formulations. Our bioprospection studies of Ageratum conyzoides plant established it as a species potentially having strong acaricidal activity due to the presence of potent acaricidal phyto-chemicals. To develop a suitable antitick natural formulation, 41 samples/fractions/formulations were prepared from the dry powder of the whole aerial part of the A. conyzoides plant using different techniques and delivery matrices. The strongest antitick effect was recorded for formulation ACF6, which demonstrated 87 ± 6% mean mortality with 57 % inhibition of oviposition in treated female ticks. Ticks treated with the ACF6 formulation showed a significant (p < 0.001) reduction in cuticular protein (1.238 ± 0.01 mg/mL) as compared to control ticks (2.928 ± 0.01 mg/mL) but no significant difference in chitin content of treated ticks and control ticks was observed. The formulation was found safe in a rat model as no significant differences in biochemical and haematological parameters among treated and control rats were noted. Histopathological studies indicated no sign of hepatocellular necrosis and no significant changes in the weights of liver and spleen was recorded. The overall in vivo efficacy of the formulation was 85 % for experimentally infested cattle with direct mortality of more than 80 % within 96 h post-application. The lethal effect of the formulation was in the form of drying and dead ticks 1-2 d after application. The developed formulation has the potential to be adopted as an alternative tick control measure in an ecofriendly manner.
journal_name
Ticks Tick Borne Disjournal_title
Ticks and tick-borne diseasesauthors
Shanmuganath C,Kumar S,Singh R,Sharma AK,Saminathan M,Saini M,Chigure G,Fular A,Kumar R,Juliet S,Upadhaya D,Kumar B,Srivastava S,Ghosh Sdoi
10.1016/j.ttbdis.2021.101655subject
Has Abstractpub_date
2021-01-19 00:00:00pages
101655issue
3eissn
1877-959Xissn
1877-9603pii
S1877-959X(21)00008-Xjournal_volume
12pub_type
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journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2018.04.010
更新日期:2018-07-01 00:00:00
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journal_title:Ticks and tick-borne diseases
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doi:10.1016/j.ttbdis.2019.101282
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journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2015.03.011
更新日期:2015-04-01 00:00:00
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journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2012.11.010
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journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2020.101381
更新日期:2020-05-01 00:00:00
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journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2019.02.016
更新日期:2019-04-01 00:00:00
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journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2020.101543
更新日期:2020-11-01 00:00:00
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journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2010.09.004
更新日期:2010-12-01 00:00:00
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journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2015.12.010
更新日期:2016-03-01 00:00:00
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journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2018.05.002
更新日期:2018-07-01 00:00:00
abstract::Despite evidence to the effect that there is low parental adoption of tick-bite personal protective behavior (PPB) for their children - a population at high risk for tick exposure, very limited information is available on factors associated with parental adoption of PPB. The objective of this study was to identify the...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2020.101647
更新日期:2021-03-01 00:00:00
abstract::Ixodes affinis Neumann (1899) and Ixodes scapularis Say (1821) are tick vectors of the etiologic agent of Lyme disease, Borrelia burgdorferi sensu stricto. Ixodes affinis and I. scapularis are morphologically very similar, and as they are sympatric in the mid- and south-Atlantic U.S. coastal states, their accurate ide...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2013.08.003
更新日期:2014-02-01 00:00:00
abstract::Tick-borne encephalitis (TBE) is the most important viral infection transmitted by ticks in Central Europe. In Germany, where TBE was classified as a notifiable disease in 2001, a highly variable number of clinically apparent human cases was reported in the last few years, ranging from the lowest number of 238 in 2007...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2009.11.002
更新日期:2010-03-01 00:00:00
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journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2020.101471
更新日期:2020-09-01 00:00:00
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journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2020.101625
更新日期:2021-03-01 00:00:00
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journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2020.101597
更新日期:2021-01-01 00:00:00
abstract::Tick-borne encephalitis virus (TBEV) is a zoonotic agent causing severe encephalitis in humans. A wide range of animal species could be infected with TBEV in endemic areas. A serological survey of wild animals is effective in identifying TBEV-endemic areas. Safe, simple, and reliable TBEV serodiagnostic tools are need...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2016.03.002
更新日期:2016-07-01 00:00:00
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journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2015.03.004
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journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2017.05.007
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journal_title:Ticks and tick-borne diseases
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journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2013.02.002
更新日期:2013-06-01 00:00:00
abstract::A marked increase in tick-borne encephalitis (TBE) incidence has been observed in Europe during the last 2 decades. Hypothetical causes include global climatic fluctuations, human-induced environmental changes, and socio-economic changes. These factors are thought to be disproportionately relevant in different geograp...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2010.05.003
更新日期:2010-09-01 00:00:00
abstract::Bovine anaplasmosis is a globally economically important tick-borne disease caused by the obligate intraerythrocytic rickettsia, Anaplasma marginale. A live Anaplasma centrale blood-based vaccine is available, but it does not protect against all A. marginale field strains and may also transmit other blood-borne pathog...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2020.101444
更新日期:2020-07-01 00:00:00
abstract::Suspicion of Brazilian spotted fever (BSF) should occur in endemic regions upon surveillance of the acute febrile icteric hemorrhagic syndrome (AFIHS). However, limitations associated with currently available laboratory tests pose a challenge to early diagnosis, especially in fatal cases. Two real-time PCR (qPCR) prot...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2012.10.027
更新日期:2012-12-01 00:00:00
abstract::The current work evaluated road-killed Pampas foxes (Lycalopex gymnocercus) and their ticks for the presence of vector-borne agents in the ecoregion Esteros del Iberá in northeastern Argentina. Spleen, lung and blood samples and Amblyomma tigrinum adult ticks collected from the foxes were tested by polymerase chain re...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2019.101318
更新日期:2020-03-01 00:00:00
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journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2020.101493
更新日期:2020-09-01 00:00:00
abstract::Rickettsia parkei is the etiological agent of spotted fever in Uruguay, where is transmitted to humans by the tick Amblyomma triste. In the present study, ticks were collected from capybaras (Hydrochoerus hydrochaeris) and domestic dogs during 2011-2012 in different parts of Uruguay. Three out of 11 (27.3%) Amblyomma ...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2014.04.021
更新日期:2014-10-01 00:00:00
abstract::Equine piroplasmosis (EP) is an important tick-borne disease of equids, caused by Theileria equi and Babesia caballi. It is endemic in most parts of the world, including Israel, and has clinical and economic consequences. This study was set to evaluate the presence of EP parasites in domestic donkeys and in wild equid...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2019.101286
更新日期:2020-01-01 00:00:00
abstract::Attempts to eliminate Rhipicephalus microplus from Uruguay have been unsuccessful, and, currently, the country is divided into two areas: a tick-free area and a tick-infested area. In the tick-infested area, different farms face different situations. Some farms are in regions where, due to environmental conditions or ...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2019.04.009
更新日期:2019-06-01 00:00:00
abstract::The seasonal risk to humans of picking up Ixodes ricinus ticks in different habitats at 3 recreational sites in the UK was assessed. A comprehensive range of vegetation types was sampled at 3-weekly intervals for 2 years, using standard blanket-dragging complemented by woollen leggings and square 'heel flags'. Ticks w...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2011.03.002
更新日期:2011-06-01 00:00:00