Acute myeloid leukemia in the pregnant patient.

abstract：:A subset of 299 patients with homozygous sickle cell anaemia, enrolled in the cohort of the French Study Group on sickle cell disease (SCD), was investigated in this study. The majority of patients were children (mean age 10.1 +/- 5.8 yr) of first generation immigrants from Western and Central Africa, the others origi...

journal_title：European journal of haematology

authors： Neonato MG,Guilloud-Bataille M,Beauvais P,Bégué P,Belloy M,Benkerrou M,Ducrocq R,Maier-Redelsperger M,de Montalembert M,Quinet B,Elion J,Feingold J,Girot R

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:Both carcinoma of the prostate and non-Hodgkin's lymphoma are common in elderly patients. Measurement of serum prostate-specific antigen (PSA) is a frequently used tool to diagnose and monitor prostate carcinoma and is generally specific for diseases of the prostate. CASE:We describe a 68-yr-old patient with...

journal_title：European journal of haematology

authors： Oosterheert JJ,Budel LM,Vos P,Wittebol S

更新日期：2007-08-01 00:00:00

abstract：:Antigenic concentration of total kininogen, kinin liberated in vitro, and the antigenic concentration of high molecular weight (HMW) kininogen was measured in 58 different samples of cord blood plasma and in plasma samples from 67 healthy blood donors. Total kininogen and kinin concentration in cord blood plasma was m...

journal_title：European journal of haematology

authors： Kleniewski J,Czokało M

更新日期：1991-05-01 00:00:00

abstract：:10 patients with CLL and 2 with CML were treated with gradually increasing doses of 1 alpha(OH)D3, up to 4 micrograms daily during 6 wk. 3 patients with preleukemia and 1 with myelofibrosis were treated with 2 micrograms daily of 1 alpha(OH)D3 for a prolonged period up to 17 wk. The treatment with 1 alpha (OH)D3 did n...

journal_title：European journal of haematology

authors： Wieslander SB,Mortensen BT,Binderup L,Nissen NI

更新日期：1987-07-01 00:00:00

abstract：:The association of infectious mononucleosis and an immunocompromised host such as occurs in acute leukemia is reported. The most common cause of infectious mononucleosis is Epstein-Barr virus (EBV) and cytomegalovirus (CMV). Patients with mononucleosis syndrome caused by other agents are rare. We report a case of acut...

journal_title：European journal of haematology

authors： Tamayose K,Sugimoto K,Ando M,Oshimi K

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVE:The mutational status of the immunoglobulin (Ig) V(H) gene in B-cell chronic lymphocytic leukaemia (B-CLL) identifies two subgroups of patients with significantly different outcomes. We investigated the association of ZAP-70 expression with IgVH mutational status in B-CLL by quantifying ZAP-70 mRNA, to evalua...

journal_title：European journal of haematology

authors： Catherwood MA,Matthews C,Niblock R,Dobbin E,Morris TC,Alexander HD

更新日期：2006-04-01 00:00:00

abstract：:Relapse represents the most significant cause of failure of allogeneic hematopoietic stem cell transplantation (HSCT) for FLT3-ITD-positive acute myeloid leukemia (AML), and available therapies are largely unsatisfactory. In this study, we retrospectively collected data on the off-label use of the tyrosine kinase inhi...

journal_title：European journal of haematology

authors： De Freitas T,Marktel S,Piemontese S,Carrabba MG,Tresoldi C,Messina C,Lupo Stanghellini MT,Assanelli A,Corti C,Bernardi M,Peccatori J,Vago L,Ciceri F

更新日期：2016-06-01 00:00:00

abstract：:In addition to BCR, various rare fusion partners for the ABL1 gene have been reported in leukemia. We have identified the fusion gene SNX2-ABL1 in a pediatric case of acute lymphoblastic leukemia (ALL), which has only once previously been reported in an adult patient. Cytogenetic analysis detected this fusion gene ari...

journal_title：European journal of haematology

authors： Masuzawa A,Kiyotani C,Osumi T,Shioda Y,Iijima K,Tomita O,Nakabayashi K,Oboki K,Yasuda K,Sakamoto H,Ichikawa H,Hata K,Yoshida T,Matsumoto K,Kiyokawa N,Mori T

更新日期：2014-03-01 00:00:00

abstract：:Hemoglobinopathies are the most common autosomal recessive disorders and are mostly inherited in a recessive manner. However, certain mutations can affect the globin chain stability, leading to dominant forms of thalassemia. The aim of this work was the molecular and structural characterization of two heterozygous in-...

journal_title：European journal of haematology

authors： Scheps KG,Hasenahuer MA,Parisi G,Targovnik HM,García E,Veber ES,Crisp R,Elena G,Varela V,Fornasari MS

更新日期：2018-06-01 00:00:00

abstract：:Few risk factors have been established for the plasma cell disorder multiple myeloma, but some of these like African American ethnicity and a family history of B-cell lymphoproliferative diseases suggest a genetic component for the disease. Genetic variation represents the genetic basis of variability in a population....

journal_title：European journal of haematology

authors： Vangsted A,Klausen TW,Vogel U

更新日期：2012-01-01 00:00:00

abstract：:Very high-dose chemotherapy with autologous blood stem cell (BSC) rescue becomes more and more widely performed. In order to simplify the technique, a large volume apheresis programme combined with an uncontrolled rate cryopreservation at -80 degrees C was developed. Twenty-six patients suffering from multiple myeloma...

journal_title：European journal of haematology

authors： Feremans WW,Bastin G,Moine FL,Ravoet C,Delville JP,Pradier O,Wallef G,Dupont E,Capel P,Lambermont M

更新日期：1996-05-01 00:00:00

abstract：OBJECTIVES:The benefits of combined chelation therapy with daily deferiprone (DFP) and subcutaneous desferrioxamine (DFO) have been widely reported in literature. We retrospectively evaluated the efficacy of different schedules of combined chelation therapy and the incidence of adverse events. METHODS:We evaluated 36 ...

journal_title：European journal of haematology

authors： Ricchi P,Ammirabile M,Spasiano A,Costantini S,Cinque P,Di Matola T,Pagano L,Prossomariti L

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVES:The current study identified patients with either essential thrombocythemia (ET) or polycythemia vera (PV) who have survived for at least 20 yr without the development of either acute myeloid leukemia/myelodysplastic syndrome (AML/MDS) or myelofibrosis (MF) and compared their presenting features with those i...

journal_title：European journal of haematology

authors： Tefferi A,Gangat N,Wolanskyj AP,Schwager S,Pardanani A,Lasho TL,Mesa R,McClure RF,Li CY,Hanson CA

更新日期：2008-05-01 00:00:00

abstract：:Alkaline phosphatase (ALP) activity of 70 cases of non-Hodgkin's lymphomas of the B-cell type was studied. ALP activity was found in malignant lymphoma (ML), follicular, small cleaved cell (1/5 cases); ML, diffuse, small cleaved cell (3/13 cases); and mantle zone lymphoma (intermediate lymphocytic lymphoma) (2/2 cases...

journal_title：European journal of haematology

authors： Abe M,Nozawa Y,Wachi E,Tominaga K,Hojo H,Wakasa H

更新日期：1988-09-01 00:00:00

abstract：OBJECTIVE:We report an extension study of patients with essential thrombocythaemia (ET) in the Hungarian Myeloproliferative Neoplasm (HUMYPRON) Registry, which demonstrated that over 6 years anagrelide significantly decreased the number of patients experiencing minor arterial and minor venous thrombotic events (TEs) vs...

journal_title：European journal of haematology

authors： Kellner A,Dombi P,Illes A,Demeter J,Homor L,Ercsei I,Simon Z,Karadi E,Herczeg J,Gy Korom V,Gasztonyi Z,Szerafin L,Udvardy M,Egyed M

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:Despite effective preemptive and prophylactic therapeutic strategies, cytomegalovirus (CMV) seropositivity of either recipient and/or donor still remains an important parameter for outcome even after reduced-intensity allogeneic stem cell transplantation (SCT). Whether CMV seropositivity of the donor might h...

journal_title：European journal of haematology

authors： Nachbaur D,Clausen J,Kircher B

更新日期：2006-05-01 00:00:00

abstract：:Bcl-2 expression, the number of apoptotic cells and the growth and differentiation of early bone marrow progenitor cells were studied in patients with confirmed diagnosis of acute myeloid leukaemia (AML). Bone marrow cells from normal individuals were used as controls. We observed an increased percentage of bcl-2-mono...

journal_title：European journal of haematology

authors： Bincoletto C,Saad ST,da Silva ES,Queiroz ML

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:To determine the financial and psycho-social impact of participation in clinical trials of patients with BCR/ABL-negative myeloproliferative neoplasms (MPN). METHODS:An international, observational cross-sectional study was performed in 143 consecutive MPN patients (51% myelofibrosis, 36% polycythemia vera, ...

journal_title：European journal of haematology

authors： Goel S,Paoli C,Iurlo A,Pereira A,Efficace F,Barbui T,Tefferi A,Vannucchi AM,Cervantes F

更新日期：2017-07-01 00:00:00

abstract：:Downregulation of cereblon (CRBN) gene expression is associated with resistance to the immunomodulatory drug lenalidomide and poor survival outcomes in multiple myeloma (MM) patients. However, the importance of CRBN gene expression in patients with myelodysplastic syndrome (MDS) and its impact on lenalidomide therapy ...

journal_title：European journal of haematology

authors： Jonasova A,Bokorova R,Polak J,Vostry M,Kostecka A,Hajkova H,Neuwirtova R,Siskova M,Sponerova D,Cermak J,Mikulenkova D,Cervinek L,Brezinova J,Michalova K,Fuchs O

更新日期：2015-07-01 00:00:00

abstract：:High mobility group box 1 protein (HMGB1), originally described as a non-histone, DNA binding protein, was recently identified as a late mediator of inflammation via its extracellular release from activated macrophages/monocytes. In the present study, we report that intracellular HMGB1 synergizes with a macrophage/mon...

journal_title：European journal of haematology

authors： Mouri F,Tsukada J,Mizobe T,Higashi T,Yoshida Y,Minami Y,Izumi H,Kominato Y,Kohno K,Tanaka Y

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:The extent of disease in patients with multiple myeloma or related conditions may be difficult to assess. In previous small studies, both FDG-PET (PET) and Tc-99m sestamibi scans (MIBI) have identified sites of occult disease in myeloma. METHODS:We reviewed the results for patients at our institution who hav...

journal_title：European journal of haematology

authors： Mileshkin L,Blum R,Seymour JF,Patrikeos A,Hicks RJ,Prince HM

更新日期：2004-01-01 00:00:00

abstract：:The use of rituximab is increasing and regular administration over 2 to 3 h requires considerable healthcare resources and is inconvenient for patients. There is interest in reducing rituximab administration times and although infusion of rituximab over 90 min is safe, there is limited data on the safety of 60 min inf...

journal_title：European journal of haematology

authors： Tuthill M,Crook T,Corbet T,King J,Webb A

更新日期：2009-04-01 00:00:00

abstract：:The clinicopathological features of human immunodeficiency virus (HIV)-associated lymphoma were investigated in a retrospective study of 85 adult patients in eastern Denmark diagnosed during the period 1990-1996. The possible pathogenetic role of Epstein-Barr virus (EBV) and human herpesvirus 8 (HHV-8) in these tumour...

journal_title：European journal of haematology

authors： Hansen PB,Penkowa M,Kirk O,Skinhøj P,Pedersen C,Lisse I,Kiss K,Zhou X,Hamilton-Dutoit SJ

更新日期：2000-06-01 00:00:00

abstract：:Upshaw-Schulman syndrome (USS) is due to severe congenital deficiency of von Willebrand factor (VWF)-cleaving protease ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 domains, nr 13) activity resulting in the presence of unusually large forms of VWF in the circulation, causing intravascular plat...

journal_title：European journal of haematology

authors： Rank CU,Kremer Hovinga J,Taleghani MM,Lämmle B,Gøtze JP,Nielsen OJ

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Non-Hodgkin lymphoma patients have a 25% increased risk of secondary primary neoplasms (SPNs). Regarding the controversy about the increased risk of SPN in patients exposed to radioimmunotherapy (RIT), we have analyzed this issue in a cohort of follicular lymphoma (FL) patients treated with/without RIT. PAT...

journal_title：European journal of haematology

authors： Andrade-Campos MM,Liévano P,Espinosa-Lara N,Soro-Alcubierre G,Grasa-Ulrich JM,López-Gómez L,Baringo T,Giraldo P

更新日期：2016-12-01 00:00:00

abstract：:Spontaneous remission in patients with acute myeloid leukemia (AML) is a rarely reported phenomenon of usually short duration. The etiology remains unclear, but an association with preceding blood transfusions or bacterial infections has been reported. Triggered immune responses are suggested to play a potential role ...

journal_title：European journal of haematology

authors： Müller CI,Trepel M,Kunzmann R,Lais A,Engelhardt R,Lübbert M

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:This review describes the safety of deferoxamine (DFO), deferiprone (DFP), deferasirox (DFX) and combined therapy in young patients less than 25 yr of age with haemoglobinopathies. METHODS:Searches in electronic literature databases were performed. Studies reporting adverse events associated with iron chela...

journal_title：European journal of haematology

authors： Botzenhardt S,Li N,Chan EW,Sing CW,Wong IC,Neubert A

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:Hematological treatment decisions in older adults with hematological malignancies are complex. Our objective is to study the impact of a comprehensive geriatric assessment on hematological treatment decision in older patients and the factors associated with change in treatment plan. METHODS:We conducted a cr...

journal_title：European journal of haematology

authors： Garric M,Sourdet S,Cabarrou B,Steinmeyer Z,Gauthier M,Ysebaert L,Beyne-Rauzy O,Gerard S,Lozano S,Brechemier D,Filleron T,Mourey L,Balardy L

更新日期：2020-12-19 00:00:00

abstract：UNLABELLED:Protein C (PC) deficiency is an autosomal dominant inherited disorder associated with spontaneous and recurrent thrombotic events. Factor V Leiden (FVL) increases the risk of thrombosis in PC-deficient type I families. We have investigated the relationship between PC deficiency genotype and clinical phenotyp...

journal_title：European journal of haematology

authors： Cafolla A,D'Andrea G,Baldacci E,Margaglione M,Mazzucconi MG,Foà R

更新日期：2012-04-01 00:00:00

abstract：AIMS:Aim of the study is to investigate diffuse large B-cell lymphoma (DLBCL) for the presence of BCL3 gene rearrangement and protein expression and to correlate these with immunophenotypic subsets of DLBCL. We aimed to investigate the pathogenetic implication of BCL3 in DLBCL. METHODS AND RESULTS:Tissue microarray se...

journal_title：European journal of haematology

authors： Ibrahim HA,Amen F,Reid AG,Naresh KN

更新日期：2011-12-01 00:00:00