Rapid and body weight-independent improvement of endothelial and high-density lipoprotein function after Roux-en-Y gastric bypass: role of glucagon-like peptide-1.

abstract：BACKGROUND:Myocardial injury from ischemia can be aggravated by reperfusion of the jeopardized area. The precise underlying mechanisms have not been clearly defined, but proinflammatory events, including complement activation, leukocyte adhesion, and infiltration and release of diverse mediators, probably play importan...

journal_title：Circulation

authors： Horstick G,Heimann A,Götze O,Hafner G,Berg O,Böhmer P,Becker P,Darius H,Rupprecht HJ,Loos M,Bhakdi S,Meyer J,Kempski O

更新日期：1997-02-04 00:00:00

abstract：BACKGROUND:The morphological hallmark of tetralogy of Fallot is controversial, with much disagreement as to whether the subpulmonary infundibulum in this lesion is hypoplastic. In addition, few quantitative data are available regarding the morphometry of the subpulmonary infundibulum, what anatomic characteristics are ...

journal_title：Circulation

authors： Geva T,Ayres NA,Pac FA,Pignatelli R

更新日期：1995-08-15 00:00:00

abstract：BACKGROUND:-Recent studies have suggested that testosterone has a protective effect in the arterial vascular system. However, little is known about the molecular aspects of the mechanism(s) involved in these processes. The aim of the present study was to investigate the effect of testosterone on neointimal plaque devel...

journal_title：Circulation

authors： Hanke H,Lenz C,Hess B,Spindler KD,Weidemann W

更新日期：2001-03-13 00:00:00

abstract：:Venous thromboembolism (VTE) is a major preventable disease that affects hospitalized inpatients. Risk stratification and prophylactic measures have good evidence supporting their use, but multiple reasons exist that prevent full adoption, compliance, and efficacy that may underlie the persistence of VTE over the past...

journal_title：Circulation

authors： Henke PK,Kahn SR,Pannucci CJ,Secemksy EA,Evans NS,Khorana AA,Creager MA,Pradhan AD,American Heart Association Advocacy Coordinating Committee.

更新日期：2020-06-16 00:00:00

abstract：:This study was undertaken to provide a better anatomic description of the location and course of the left coronary artery within a commonly used ultrasonic tomographic plane. Twenty-three hearts were excised at autopsy and scanned in vitro. The locations of the left main (LMCA), left anterior descending (LAD), and lef...

journal_title：Circulation

authors： Rogers EW,Feigenbaum H,Weyman AE,Godley RW,Vakili ST

更新日期：1980-10-01 00:00:00

abstract：BACKGROUND:Endothelial dysfunction of coronary arteries with impaired vasodilation has been reported in patients with arterial hypertension. However, the effect of dynamic exercise on coronary vasomotion of a stenotic vessel segment before and after PTCA has not yet been evaluated in these patients. METHODS AND RESULT...

journal_title：Circulation

authors： Frielingsdorf J,Kaufmann P,Suter T,Hug R,Hess OM

更新日期：1998-09-22 00:00:00

abstract：:Systolic time intervals, stroke volume, cardiac output and (dZ/dt)/RZ index were serially estimated in 51 normal healthy volunteers at sea level, for ten days after air induction to 3658 m altitude and on return to sea level. The subjects were divided into three groups and were administered a diuretic, beta methyldigo...

journal_title：Circulation

authors： Balasubramanian V,Behl A,Das GS,Wadhwa AK,Mathew OP,Hoon RS

更新日期：1978-06-01 00:00:00

abstract：:Experimental studies have suggested that electrocardiographic recognition of left ventricular hypertrophy depends on geometric relationships involving wall thickness and chamber size. To determine the clinical significance of these observations, we studied the effects of echocardiographic LV mass (LVM), posterior wall...

journal_title：Circulation

authors： Devereux RB,Phillips MC,Casale PN,Eisenberg RR,Kligfield P

更新日期：1983-04-01 00:00:00

abstract：BACKGROUND:The physiological assessment of angiographically intermediate-severity stenoses remains problematic. Functional measurements of poststenotic intracoronary Doppler coronary flow reserve can be performed in humans but have not been correlated with hyperemic myocardial perfusion imaging or angiographic data in ...

journal_title：Circulation

authors： Miller DD,Donohue TJ,Younis LT,Bach RG,Aguirre FV,Wittry MD,Goodgold HM,Chaitman BR,Kern MJ

更新日期：1994-05-01 00:00:00

abstract：:Syncope and sudden death occurs in certain purebred Pug dogs which have been found to have intermittent sinus pauses and paroxysmal second degree heart block on electrocardiographic (ECG) study. We have established a colony of such dogs to study this problem and here report the results of histological examination of t...

journal_title：Circulation

authors： James TN,Robertson BT,Waldo AL,Branch CE

更新日期：1975-12-01 00:00:00

abstract：BACKGROUND:Gene-nutrient interactions affecting high-density lipoprotein cholesterol (HDL-C) concentrations may contribute to the interindividual variability of the cardiovascular disease risk associated with dietary fat intake. Hepatic lipase (HL) is a key determinant of HDL metabolism. Four polymorphisms in linkage d...

journal_title：Circulation

authors： Ordovas JM,Corella D,Demissie S,Cupples LA,Couture P,Coltell O,Wilson PW,Schaefer EJ,Tucker KL

更新日期：2002-10-29 00:00:00

abstract：:Power outputs that are below the anaerobic threshold (theta an) may be sustained for prolonged durations, whereas power outputs that are greater than theta an result in a significant reduction in the tolerable duration to fatigue. The theta an may therefore be considered to demarcate exercise intensity into moderate (...

journal_title：Circulation

authors： Whipp BJ

更新日期：1987-12-01 00:00:00

abstract：:Two hundred-three patients had -echnetium 99m (stannous) pyrophosphate myocardial scintigrams for the evaluation of chest pain and suspected acute myocardial infarction. In addition to routine imaging at 60--90 minutes after injection of the radio-pharmaceutical, the blood pool was imaged immediately in each patient f...

journal_title：Circulation

authors： Cowley MJ,Mantle JA,Rogers WJ,Russel RO Jr,Rackley CE,Logic JR

更新日期：1977-08-01 00:00:00

abstract：BACKGROUND:We have previously shown major differences in beta-adrenergic and muscarinic modulation of L-type calcium currents (ICa) in newborn and adult rabbit heart. However, little is known about developmental changes in modulation of ICa by phosphodiesterases (PDEs), which also regulate intracellular cAMP concentrat...

journal_title：Circulation

authors： Akita T,Joyner RW,Lu C,Kumar R,Hartzell HC

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Increased plasma levels of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) have been identified as predictors of cardiac dysfunction and prognosis in congestive heart failure and ischemic heart disease. In severe sepsis patients, however, no information is available yet about the prognos...

journal_title：Circulation

authors： Brueckmann M,Huhle G,Lang S,Haase KK,Bertsch T,Weiss C,Kaden JJ,Putensen C,Borggrefe M,Hoffmann U

更新日期：2005-07-26 00:00:00

abstract：:We performed a 15 year follow-up of 748 patients undergoing bypass surgery, comparing 532 patients with one or two internal mammary artery grafts with or without additional saphenous vein grafts to 216 patients with saphenous vein grafts alone. During the 15 years of follow-up the 532 patients with at least one intern...

journal_title：Circulation

authors： Cameron A,Kemp HG Jr,Green GE

更新日期：1986-11-01 00:00:00

abstract：:In 61 patients sinus node function was tested by programmed (sinoatrial conduction time, SACT) and overdrive atrial pacing (sinus node recovery time, SRT). In the control group (N = 20), mean sinus cycle length was 773 +/- 140.2 msec, mean absolute SRT 1044 +/- 215.8 msec [corrected SRT (CSRT) 270 +/- 112.5 msec; mean...

journal_title：Circulation

authors： Breithardt G,Seipel L,Loogen F

更新日期：1977-07-01 00:00:00

abstract：BACKGROUND:Microsomal (m) prostaglandin (PG) E₂ synthase (S)-1 catalyzes the formation of PGE₂ from PGH₂, a cyclooxygenase product that is derived from arachidonic acid. Previous studies in mice suggest that targeting mPGES-1 may be less likely to cause hypertension or thrombosis than cyclooxygenase-2-selective inhibit...

journal_title：Circulation

authors： Wang M,Ihida-Stansbury K,Kothapalli D,Tamby MC,Yu Z,Chen L,Grant G,Cheng Y,Lawson JA,Assoian RK,Jones PL,Fitzgerald GA

更新日期：2011-02-15 00:00:00

abstract：:Ventricular dysfunction, elevated pulmonary vascular resistance, and residual distal pulmonary artery distortion contribute to early mortality after a Fontan operation; they may be transient or reversible. A baffle fenestration, allowing right-to-left shunting, maintains cardiac output and limits right atrial pressure...

journal_title：Circulation

authors： Bridges ND,Lock JE,Castaneda AR

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Ultrafast computed tomography (CT), by acquiring images of the proximal coronary arteries, detects coronary calcifications and has been demonstrated to be highly sensitive for the detection of coronary artery disease in many small studies. The aim of this study was to determine the relationship between ultra...

journal_title：Circulation

authors： Budoff MJ,Georgiou D,Brody A,Agatston AS,Kennedy J,Wolfkiel C,Stanford W,Shields P,Lewis RJ,Janowitz WR,Rich S,Brundage BH

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Transfer of the coronary arteries is a crucial step during the arterial switch operation (ASO) for transposition of the great arteries. This retrospective study aims to assess the incidence and risk factors of coronary events after ASO and sensitivity of noninvasive tests in the diagnosis of the coronary obs...

journal_title：Circulation

authors： Legendre A,Losay J,Touchot-Koné A,Serraf A,Belli E,Piot JD,Lambert V,Capderou A,Planche C

更新日期：2003-09-09 00:00:00

abstract：BACKGROUND:The relation between left ventricular (LV) oxygen consumption (MVO2) and pressure-volume area (PVA) developed in isolated hearts provides a powerful method to understand cardiac energetics. We investigated application of this relation to the intact circulation, determining its response to steady-state and tr...

journal_title：Circulation

authors： Nozawa T,Cheng CP,Noda T,Little WC

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:Pregnant women with congenital heart disease (CHD) are susceptible to cardiovascular, obstetric, and offspring complications. In women with CHD, cardiac dysfunction may compromise uteroplacental flow and contribute to the increased incidence of obstetric and offspring events. METHODS AND RESULTS:We performe...

journal_title：Circulation

authors： Pieper PG,Balci A,Aarnoudse JG,Kampman MA,Sollie KM,Groen H,Mulder BJ,Oudijk MA,Roos-Hesselink JW,Cornette J,van Dijk AP,Spaanderman ME,Drenthen W,van Veldhuisen DJ,ZAHARA II investigators.

更新日期：2013-12-03 00:00:00

abstract：:There is now evidence that under resting conditions coronary vasodilator reserve exists even in the presence of myocardial ischemia. Therefore, we tested the hypothesis that a vasodilator reserve may exist during exercise so that during exercise-induced ischemia a reduction in coronary constrictor tone can be produced...

journal_title：Circulation

authors： Heusch G,Guth BD,Seitelberger R,Ross J Jr

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Alterations in the balance of matrix metalloproteinases (MMPs) and their specific tissue inhibitors (TIMPs) are involved in left ventricular (LV) remodeling. Whether their expression is related to interstitial fibrosis or LV dysfunction in patients with chronic pressure overload-induced LV hypertrophy, howev...

journal_title：Circulation

authors： Heymans S,Schroen B,Vermeersch P,Milting H,Gao F,Kassner A,Gillijns H,Herijgers P,Flameng W,Carmeliet P,Van de Werf F,Pinto YM,Janssens S

更新日期：2005-08-23 00:00:00

abstract：BACKGROUND:Unfractionated heparin has been the primary anticoagulant therapy for percutaneous coronary intervention for >20 years. Despite the availability of rapid "point of care" testing, little clinical data defining the optimal level of anticoagulation are available. Furthermore, recent reports have advocated the u...

journal_title：Circulation

authors： Chew DP,Bhatt DL,Lincoff AM,Moliterno DJ,Brener SJ,Wolski KE,Topol EJ

更新日期：2001-02-20 00:00:00

abstract：BACKGROUND:Nitric oxide signaling plays a key role in the regulation of vascular tone and platelet activation. Here, we seek to understand the impact of a genetic predisposition to enhanced nitric oxide signaling on risk for cardiovascular diseases, thus informing the potential utility of pharmacological stimulation of...

journal_title：Circulation

authors： Emdin CA,Khera AV,Klarin D,Natarajan P,Zekavat SM,Nomura A,Haas M,Aragam K,Ardissino D,Wilson JG,Schunkert H,McPherson R,Watkins H,Elosua R,Bown MJ,Samani NJ,Baber U,Erdmann J,Gormley P,Palotie A,Stitziel NO,Gup

更新日期：2018-01-16 00:00:00

abstract：BACKGROUND:For decades, the coronary heart disease (CHD) mortality rate has been four or more times higher in Finland than in France despite comparable intakes of dietary cholesterol and saturated fat. A potential answer to this paradox is provided by this study of 40 countries and the analyses of other nutrients in th...

journal_title：Circulation

authors： Artaud-Wild SM,Connor SL,Sexton G,Connor WE

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:The effects of cardiac transplantation on cognitive brain function are uncertain. METHODS AND RESULTS:We measured cognitive brain function and quality of life in out-of-hospital cardiac transplant candidates (n = 55; ejection fraction, 19.9%; age, 54.8 years [means]). After transplantation, the patients wer...

journal_title：Circulation

authors： Grimm M,Yeganehfar W,Laufer G,Madl C,Kramer L,Eisenhuber E,Simon P,Kupilik N,Schreiner W,Pacher R,Bunzel B,Wolner E,Grimm G

更新日期：1996-09-15 00:00:00

abstract：BACKGROUND:Proto-oncogenes have been implicated in the pathogenesis of gene-mediated myocardial remodeling. In the human heart, however, it has not been clarified whether these proto-oncogenes are related to contractile impairment and structural alteration of the myocardium. The present study is designed to investigate...

journal_title：Circulation

authors： Taketani S,Sawa Y,Taniguchi K,Mitsuno M,Kawaguchi N,Onishi S,Matsuda H

更新日期：1997-11-04 00:00:00