Abstract:
:The opening of the tricuspid valve and the onset of right ventricular filling precede the opening of the mitral valve and the onset of flow in the normal adult. Sixty-five studies of atrioventricular flow with range-gated pulsed Doppler echocardiography, performed on 32 normal neonates, consistently demonstrated the reverse sequence. Further investigation showed that at the time of mitral valve opening, while the tricuspid valve was still closed, the valve of the foramen ovale began to bow posteriorly into the left atrium and remained posteriorly bowed for most of diastole. The magnitude of posterior bowing varied among the neonates but, concomitant with the more prominent grades of posterior bowing, right to left shunting across the foramen ovale was demonstrated on color flow mapping. Ultrasound studies in the normal fetus also revealed earlier opening of the mitral valve, bowing of the valve of the foramen ovale into the left atrium and right to left shunting across the foramen ovale. These findings indicate that in the normal immature heart isovolumic ventricular relaxation is completed earlier on the left than on the right side and that left ventricular compliance appears to be greater than right ventricular compliance. The relation of left and right ventricular compliance in the adult is different from that in the normal immature heart. Whereas systemic and pulmonary vascular resistance and pressure levels change rapidly in the newborn period, ventricular compliance matures over a longer period of time. As a result of the differential maturity, for a variable period of time in the normal neonate, a left to right ductal shunt coexists with a right to left atrial shunt.
journal_name
J Am Coll Cardioljournal_title
Journal of the American College of Cardiologyauthors
Steinfeld L,Almeida OD,Rothfeld ELdoi
10.1016/s0735-1097(88)80062-7subject
Has Abstractpub_date
1988-09-01 00:00:00pages
712-8issue
3eissn
0735-1097issn
1558-3597pii
S0735-1097(88)80062-7journal_volume
12pub_type
杂志文章abstract::Right ventricular function was assessed in 15 patients using right ventricular pressure-volume loops. Right ventricular pressure using a micromanometer-tipped catheter, thermodilution cardiac output and gated blood pool scintigrams were simultaneously obtained. To help isolate the right ventricle, a slant hole collima...
journal_title:Journal of the American College of Cardiology
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doi:10.1016/s0735-1097(84)80062-5
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abstract::Methysergide ( Sansert ) has been associated with numerous fibrotic disorders. In particular, multiple cardiac lesions have been described in cases where methysergide was thought to have played a causative role. A patient is described who presented with cardiac findings suggestive of acute myopericarditis . An inflamm...
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doi:10.1016/0735-1097(91)90556-o
更新日期:1991-11-01 00:00:00
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更新日期:2021-01-05 00:00:00
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更新日期:2001-11-01 00:00:00
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doi:10.1016/0735-1097(91)90613-e
更新日期:1991-08-01 00:00:00
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更新日期:2017-05-16 00:00:00
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更新日期:2004-12-07 00:00:00
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更新日期:1999-12-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/0735-1097(95)00246-z
更新日期:1995-09-01 00:00:00
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doi:10.1016/j.jacc.2011.08.044
更新日期:2011-11-29 00:00:00
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更新日期:2020-05-19 00:00:00
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更新日期:2002-06-19 00:00:00
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更新日期:2001-10-01 00:00:00
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更新日期:2013-09-24 00:00:00
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更新日期:1991-02-01 00:00:00
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更新日期:2016-02-23 00:00:00
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更新日期:2002-10-16 00:00:00
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更新日期:2018-12-11 00:00:00
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pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2007-11-06 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
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更新日期:2000-10-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2006-03-07 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/0735-1097(95)00551-x
更新日期:1996-03-15 00:00:00