Abstract:
:Most defects in dermatologic surgery can be repaired by primary closure. If this is not feasible, then local flaps should be employed. Where flaps are unfeasible or would result in an additional cosmetic deformity, then a full-thickness skin graft should be employed. If the defect is too large for a full-thickness skin graft, then a split-thickness skin graft is the appropriate choice. Individual surgical situations or the medical status of the patient may alter these general principles.
journal_name
Clin Dermatoljournal_title
Clinics in dermatologyauthors
Coleman W 3rddoi
10.1016/0738-081x(87)90031-9subject
Has Abstractpub_date
1987-10-01 00:00:00pages
94-109issue
4eissn
0738-081Xissn
1879-1131pii
0738-081X(87)90031-9journal_volume
5pub_type
杂志文章abstract::The introduction of sentinel lymph node biopsy (SLNB) has been an important development in the management of malignant melanoma. Lymph nodes have long been known to play a key role in melanoma metastasis. The importance of nodal staging accounted for the previous surgical practice of elective lymph node dissection (EL...
journal_title:Clinics in dermatology
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abstract::Atopic dermatitis (AD), the most prevalent inflammatory skin disease, is characterized by robust T-cell activation. The disease has several subtypes, all having a common T helper type 2 (Th2)/Th22 polarization, but it also displays differential immune skewing, such as increased Th17/interleukin 23 skewing in the skin ...
journal_title:Clinics in dermatology
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abstract::The cause and effect between ultraviolet light and cutaneous lupus erythematosus (CLE) is clear. In LE patients indeed, photosensitivity is one of the major diagnostic criteria of the systemic form of lupus erythematosus. This strong clinical association has led to the postulate that abnormal photosensitivity particip...
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journal_title:Clinics in dermatology
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abstract::Robert Koch (1843-1910) received the Nobel Prize in Medicine in 1905 for his studies of tuberculosis. He contributed significantly to microbiology, isolating also cholera and anthrax pathogens, and introducing several postulates in this field. In addition, he developed staining methods, as well as culturing and micros...
journal_title:Clinics in dermatology
pub_type: 传,历史文章,杂志文章
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abstract::Nail surgery is a special branch of hand and dermatologic surgery. It is not widely performed, and many physicians do not feel at ease to perform it. The objective of this contribution is to give a short overview of the most important surgical procedures in clinical practice. References from the literature and the aut...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
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abstract::Infective dermatitis represents a severe form of recurrent eczematous skin change that presents in childhood. It was first described in 1966. Later, the association of infective dermatitis with an underlying human T-cell lymphotropic virus infection was recognized. Chronic infective dermatitis is associated with an in...
journal_title:Clinics in dermatology
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doi:10.1016/j.clindermatol.2008.10.007
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abstract::Different physical treatments may be used in acne therapy. The main indications are for treating retentional lesions (open and comedones), inflamed lesions, and scars. ...
journal_title:Clinics in dermatology
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doi:10.1016/j.clindermatol.2004.03.017
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abstract::Since the introduction of botulinum toxin (BTX) as a therapeutic tool in the 1970s, the number of uses for this substance has increased exponentially. BTX's mechanism of action involves degrading the SNARE proteins blockading the release of acetylcholine into the neuromuscular junction. In many body systems, decrease ...
journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
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abstract::Facial erythema (the "red face") is a straightforward clinical finding, and it is evident even to the untrained eye; however, a red face does not represent a single cutaneous entity. It may be due to a plethora of distinct underlying conditions of varying severity, including rosacea, demodicosis, dermatomyositis, lupu...
journal_title:Clinics in dermatology
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abstract::The use of many drugs in dermatologic diseases may cause ocular side effects. Some may regress after discontinuation of the therapy, but others persist or progress even after the cessation of treatment. This review presents four groups of commonly prescribed drugs-antimalarial medicines, glucocorticoids, retinoids, an...
journal_title:Clinics in dermatology
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abstract::Robert Remak was the first scientist to undertake successful research on fungal skin infections. A neurologist, physiologist, and embryologist, Remak was the first to observe the fungal changes causing the disease of favus; however, he gave credit for the discovery to Professor Johann Schönlein and denied all attempts...
journal_title:Clinics in dermatology
pub_type: 传,历史文章,杂志文章
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abstract::Skin cancer is both common and responsible for significant morbidity and mortality. Opportunities for both primary and secondary prevention are available to both dermatologists and non-dermatologists. Counseling selected patients about ultraviolet avoidance and proper use of sunscreens is recommended. Due to technical...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2013.05.002
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journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2010.03.007
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abstract::In the late 1950s and early1960s, there was a concerted effort to modernize teaching, training, and patient care in the Vargas Hospital of Caracas, Venezuela. The above included the development of research in the frame of postgraduate training. This effort was to be helped by USA funds and institutions but could only ...
journal_title:Clinics in dermatology
pub_type: 历史文章,杂志文章
doi:10.1016/j.clindermatol.2013.08.017
更新日期:2014-03-01 00:00:00
abstract::Despite the development of laboratory methods, dermatological symptoms are a basic index of the presence and physical course of HIV infection. HIV infection usually undergoes a long latent period, proceeds to a period of immunodeficiency-related symptoms, and ends in an advanced immunodeficiency state characterized by...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2004.07.007
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journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2007.09.007
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journal_title:Clinics in dermatology
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journal_title:Clinics in dermatology
pub_type: 历史文章,杂志文章
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abstract::The recognition of medical benefits obtained with suberythemogenic doses of natural sunlight extends back centuries. Modern medical application of phototherapy has been in place for over 100 years. It is the nature of scientific discovery to depend upon the use of new investigational methods or new devices to gain a b...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2003.08.005
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journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2019.04.005
更新日期:2019-01-01 00:00:00
abstract::White diseases are a heterogenous group characterized by hypopigmentation or depigmentation. Skin and eye color are determined by the number and size of melanosomes present. Melanin is produced by melanosomes in the melanocytes present within the epidermis of the skin, uvea, and retinal pigmented epithelium (RPE). Con...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2019.07.018
更新日期:2019-01-01 00:00:00
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journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2018.05.006
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abstract::Psoriasis is a chronic inflammatory disorder characterized by substantial psychiatric comorbidity. Historically, anecdotal observations have suggested that psychosocial distress can trigger flares of psoriasis, but over the past several decades, high-quality data from experimental studies support the assertion that st...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2018.08.009
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abstract::The hereditary disorders of connective tissues (HDCTs) encompass a spectrum of conditions linked pathophysiologically by abnormalities of collagen, fibrillin, and matrix proteins. The clinical picture ranges from morbidity because of musculoskeletal, skin, ocular and visceral pathologies to mortality from acute vascul...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2006.07.013
更新日期:2006-11-01 00:00:00
abstract::As new laser devices continue to emerge, it becomes increasingly important for the clinical dermatologist to understand the basic principles behind their operation. A fundamental understanding of how lasers interact with tissue will enable the physician to choose the most appropriate laser for a given clinical situati...
journal_title:Clinics in dermatology
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doi:10.1016/j.clindermatol.2005.10.019
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abstract::The most extensive investigations of treatment of New World cutaneous leishmaniasis have been performed against L. panamensis disease in Colombia, and the relative value of regimens shown there may be instructive for disease from other areas. In Colombia, a 90-95% cure rate was achieved with three different drug regim...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/0738-081x(96)00048-x
更新日期:1996-09-01 00:00:00
abstract::Optimal management of full-thickness wounds requires a thorough knowledge of wound-healing principles and practices. In the absence of underlying disease, almost every full-thickness wound will heal with minimal intervention; however, the process can be enhanced by judicious wound management. The first clinical decisi...
journal_title:Clinics in dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.clindermatol.2006.10.001
更新日期:2007-01-01 00:00:00
abstract::Somatic symptom disorder (SSD) is defined by the prominence of somatic symptoms associated with abnormal thoughts, feelings, and behaviors related to the symptoms, resulting in significant distress and impairment. Individuals with these disorders are more commonly encountered in primary care and other medical settings...
journal_title:Clinics in dermatology
pub_type: 杂志文章
doi:10.1016/j.clindermatol.2017.01.010
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