Psoriasis: epidemiology.

Abstract:

:Psoriasis is a chronic, inflammatory and hyperproliferative skin disease with a genetic basis. While epidermal hyperplasia and altered keratinocyte differentiation are prominent features, considerable evidence indicates that psoriasis is immunologically mediated. Recently, the identification of HLA-Cw6 as the disease allele conferring susceptibility to psoriasis has provided a focus for elucidation of these events. In this article, we will focus on the epidemiology of psoriasis and its associated arthritis.

journal_name

Clin Dermatol

journal_title

Clinics in dermatology

authors

Gudjonsson JE,Elder JT

doi

10.1016/j.clindermatol.2007.08.007

subject

Has Abstract

pub_date

2007-11-01 00:00:00

pages

535-46

issue

6

eissn

0738-081X

issn

1879-1131

pii

S0738-081X(07)00151-4

journal_volume

25

pub_type

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