Humoral immunity in renal transplantation: epitopes, Cw and DP, and complement-activating capability--an update.

abstract：BACKGROUND:Chronic renal failure (CRF) is a common complication of calcineurin inhibitor (CNI)-based immunosuppression following cardiac transplantation (HTx). The aim of this prospective study was to evaluate the impact of an immunosuppressive conversion from CNIs to mycophenolate mofetil (MMF) and steroids in cardiac...

journal_title：Clinical transplantation

authors： Groetzner J,Kaczmarek I,Schirmer J,Uberfuhr P,Gulbins H,Daebritz S,Meiser B,Reichart B

更新日期：2008-09-01 00:00:00

abstract：:Based on native CT scans of the pelvic region using a standardized calcification score, evaluation of iliac vascular calcification was performed between 2008 and 2012 prior to listing for renal transplantation in 205 patients with chronic kidney disease. Vascular calcification showed a decrease from proximal to distal...

journal_title：Clinical transplantation

authors： Kahn J,Ram LM,Eberhard K,Groselj-Strele A,Obermayer-Pietsch B,Müller H

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:It is unclear whether sirolimus, a newer immunosuppressive agent, widely used in renal transplantation, affects male sex hormone levels or sexual function. METHODS:Sex hormone profiles in male renal transplant recipients were obtained and compared between a sirolimus-treated group and a group not on sirolim...

journal_title：Clinical transplantation

authors： Lee S,Coco M,Greenstein SM,Schechner RS,Tellis VA,Glicklich DG

更新日期：2005-04-01 00:00:00

abstract：PURPOSE:Smoking is a major public health issue, and its effect on cardiovascular outcomes is well established. This study evaluates the impact of donor smoking on heart transplant (HT) outcomes. METHODS:HT recipients between January 1, 2005, and December 31, 2016, with known donor smoking status were queried from the ...

journal_title：Clinical transplantation

authors： Hussain Z,Yu M,Wozniak A,Kim D,Krepostman N,Liebo M,Raichlin E,Heroux A,Joyce C,Ilias-Basha H

更新日期：2020-10-23 00:00:00

abstract：BACKGROUND:International data on training, work, and lifestyle of transplant physicians and surgeons are scarce. Such data might help in development of uniform education paths and provide insights for young clinicians interested in this field. This study aimed at the evaluation of these data in all transplant-associate...

journal_title：Clinical transplantation

authors： Hoyer DP,Kaiser GM,Cicinnati V,Radunz S,Braun F,Greif-Higer G,Schulze M,Schmidt HJ,Paul A,Beckebaum S

更新日期：2016-09-01 00:00:00

abstract：:Kidney transplant wait-list management is becoming increasingly complex. We introduced a novel wait-list management strategy at our center, the Transplant Readiness Assessment Clinic (TRAC), whereby patients whose Kidney Allocation Scores surpass a threshold are actively managed. From January 1, 2016 through June 30, ...

journal_title：Clinical transplantation

authors： Cheng XS,Busque S,Lee J,Discipulo K,Hartley C,Tulu Z,Scandling JD,Tan JC

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:The Southeastern Kidney Transplant Coalition was created in 2010 to improve kidney transplant (KTx) rates in Georgia, North Carolina, and South Carolina. To identify dialysis staff-reported barriers to transplant, the Coalition developed a survey of dialysis providers in the region. METHODS:All dialysis uni...

journal_title：Clinical transplantation

authors： Browne T,Patzer RE,Gander J,Amamoo MA,Krisher J,Sauls L,Pastan S

更新日期：2016-04-01 00:00:00

abstract：:The aim of this study was to evaluate pancreatic function in total parenteral nutrition (TPN)-dependent children with permanent intestinal failure by measuring immunoreactive trypsinogen (IRT) levels. Between 1992 and 1996, 105 pediatric patients with permanent intestinal failure were referred to the Children's Hospit...

journal_title：Clinical transplantation

authors： Rovera GM,Sigurdsson L,Reyes J,Bouch LD,Naylor EW,Kocoshis SA

更新日期：1999-10-01 00:00:00

abstract：:Recent changes in Center for Medicare & Medicaid Services (CMS) condition for participation, using benchmark volume/outcomes requirements for certification, have been implemented. Consequently, the ability of a transplant center to assess its risk tolerance is important in successful management. An analysis of SRTR da...

journal_title：Clinical transplantation

authors： Johnson SR,Karp SJ,Curry MP,Barugel M,Rodrigue JR,Mandelbrot DA,Rogers CP,Hanto DW

更新日期：2012-05-01 00:00:00

abstract：:We performed a systematic search of the literature using the MEDLINE (through 2006) database to identify the patient-reported outcome measures of quality of life (QOL) used most often in the renal transplant literature. After applying limits and reviewing references, we identified 338 renal transplant articles with a ...

journal_title：Clinical transplantation

authors： Butt Z,Yount SE,Caicedo JC,Abecassis MM,Cella D

更新日期：2008-05-01 00:00:00

abstract：:The aim of this study was to identify indicators of outcome prior to transplantation in allogeneic hematopoietic stem cell transplantation (HCT). Clinical data of 106 patients with acute leukemia were retrospectively analyzed. We examined the role of pre-conditioning serum C-reactive protein (CRP) and ferritin levels,...

journal_title：Clinical transplantation

authors： Akı ŞZ,Suyanı E,Bildacı Y,Çakar MK,Baysal NA,Sucak GT

更新日期：2012-09-01 00:00:00

abstract：:After cardiac transplant, there is often development of restrictive cardiac physiology. Little is known about the factors that contribute to this physiology and its correlation with pathology. Heart retransplantation provides a valuable opportunity to further understand this relationship. In this study, we investigate...

journal_title：Clinical transplantation

authors： Kobashigawa JA,Itagaki BK,Razi RR,Patel JK,Chai W,Kawano MA,Goldstein Z,Kittleson MM,Fishbein MC

更新日期：2013-11-01 00:00:00

abstract：:With the increased number of long-term survivors after liver transplantation, new-onset diabetes after transplantation (NODAT) is becoming more significant in patient follow-up. However, the incidence of new-onset diabetes after living-donor liver transplantation (LDLT) has not been well elucidated. The aim of this st...

journal_title：Clinical transplantation

authors： Honda M,Asonuma K,Hayashida S,Suda H,Ohya Y,Lee KJ,Yamamoto H,Takeichi T,Inomata Y

更新日期：2013-05-01 00:00:00

abstract：:We herein report the first case of immunosuppression-associated thrombotic microangiopathy (TMA) in which an extrarenal graft was primarily affected by the characteristic microvascular lesions. Although TMA is a well-known complication of cyclosporine (CSA) or tacrolimus therapy in renal and extrarenal (liver, heart, ...

journal_title：Clinical transplantation

authors： Humar A,Jessurun J,Sharp HL,Gruessner RW

更新日期：1998-12-01 00:00:00

abstract：:Simultaneous pancreas-kidney transplantation is an established procedure for patients with type I diabetes and end-stage renal disease. Continuous advances in the operation techniques with consequent reduction of perioperative morbidity and mortality and the introduction of modern immunosuppressive agents improved not...

journal_title：Clinical transplantation

authors： Schmied BM,Müller SA,Mehrabi A,Welsch T,Büchler MW,Zeier M,Schmidt J

更新日期：2006-01-01 00:00:00

abstract：:The benefits of HLA matching have been clearly demonstrated in renal and cardiac transplantation. Recent studies suggest that HLA matching may be associated with improved survival rates for transplantation as well. However, the effect of HLA matching for lung transplantation has not been clearly demonstrated. Despite ...

journal_title：Clinical transplantation

authors： McGee C,Fox MD,Loyd JE

更新日期：1996-12-01 00:00:00

abstract：:A better understanding of the immunobiological processes and predictors of graft rejection holds promise for the development of potential therapeutic strategies and also individualization of immunosuppression. The objective of this study is to analyze the clinical relevance of immune parameters such as antidonor antih...

journal_title：Clinical transplantation

authors： Panigrahi A,Deka R,Bhowmik D,Dash SC,Tiwari SC,Guleria S,Mehta SN,Mehra NK

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:The role of advanced age live donors remains controversial because of decline in glomerular filtration rate and perceived increased risks of perioperative complications. METHODS:A retrospective review of all live donor transplants performed from January 2000 to December 2003. RESULTS:Seventy-eight live don...

journal_title：Clinical transplantation

authors： Johnson SR,Khwaja K,Pavlakis M,Monaco AP,Hanto DW

更新日期：2005-10-01 00:00:00

abstract：:Transplantation tolerance is the ultimate goal of organ transplantation. Natural regulatory T cells (Treg) have been expected to reach clinical applications for tolerance induction because their initial description. More than ten yr later, Treg have started moving from experimental animal models into clinical applicat...

journal_title：Clinical transplantation

authors： Fritzsching E,Kunz P,Maurer B,Pöschl J,Fritzsching B

更新日期：2009-12-01 00:00:00

abstract：:The infectious disease coronavirus disease 2019 (COVID-19) was declared a pandemic by the World Health Organization in March 2020. The impact of COVID-19 on solid organ transplantations, including heart transplantation, is currently unclear. Many transplant programs have been forced to swiftly re-evaluate and adapt th...

journal_title：Clinical transplantation

authors： Hsu JJ,Al-Saffar F,Ardehali R,Baas AS,Carlson M,Cruz D,Deng M,Fan A,Fraschilla S,Gaynor P,Kamath M,Kubak BM,Schaenman J,Stimpson E,Vucicevic D,Ardehali A,Nsair A

更新日期：2020-09-01 00:00:00

abstract：:Enteric drainage of secretions by anastomosing the donor duodenum to the recipient's small bowel has become common in pancreatic transplantation. While it eliminates many problems, endoscopic access to the transplanted duodenum and pancreas is made difficult. After a pancreas kidney transplant, the patient presented w...

journal_title：Clinical transplantation

authors： Green BT,Tuttle-Newhall J,Suhocki P,Smith SR,O'Connor JB

更新日期：2004-02-01 00:00:00

abstract：:Granulomatous interstitial nephritis (GIN) is a rare histologic diagnosis in renal allografts. We report three cases with GIN. Case 1: a 37-yr-old woman received a kidney from her mother. On follow-up 15 months later, serum creatinine was increased and a graft biopsy showed epithelioid granuloma in the center of massi...

journal_title：Clinical transplantation

authors： Hotta K,Fukasawa Y,Sasaki H,Seki T,Togashi M,Harada H

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:As Gastroesophageal reflux disease (GORD) affects long-term survival in lung transplant recipients, the aim of this observational prospective study was to analyze the efficacy of The Reflux Symptom Index Questionnaire (RSI) compared to the esophageal impedance test. METHODS:Both esophageal impedance studies ...

journal_title：Clinical transplantation

authors： Soresi S,Zeriouh M,Sabashnikov A,Mc Dermott G,Weymann A,Wippermann J,Wahlers T,Reed A,Carby M,Simon AR,Popov AF

更新日期：2016-01-01 00:00:00

abstract：:Acute renal failure is a significant risk factor for death in patients with liver failure. The goal of this study was to analyze the impact of peri-transplant dialysis on the long-term mortality of liver transplant recipients. We performed a single-center, retrospective cohort study of 743 adult liver transplants; pat...

journal_title：Clinical transplantation

authors： Zand MS,Orloff MS,Abt P,Patel S,Tsoulfas G,Kashyap R,Jain A,Safadjou S,Bozorgzadeh A

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:With the aim to improve the inferior outcomes in elderly recipients of kidneys from elderly cadaver donors, we applied and investigated a therapeutic regimen consisting of calcineurin inhibitor (CNI)-free, mycophenolate mofetil (MMF)-based immunosuppressive (i.s.) induction/maintenance protocol. In this arti...

journal_title：Clinical transplantation

authors： Arbogast H,Hückelheim H,Schneeberger H,Illner WD,Tarabichi A,Fertmann J,Wimmer CD,Hillebrand GF,Mistry-Burchardi N,Thomae R,Acikgöz A,Land W

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:We examined the risk of adverse pregnancy outcomes in primiparous kidney donors compared to matched controls. METHODS:Fifty-nine women with a history of kidney donation prior to their first pregnancy with normal renal function and no history of kidney disease, diabetes or chronic hypertension were matched 1...

journal_title：Clinical transplantation

authors： Davis S,Dylewski J,Shah PB,Holmen J,You Z,Chonchol M,Kendrick J

更新日期：2019-01-01 00:00:00

abstract：:The study included 110 consecutive patients with hematological malignancies receiving fludarabine-based reduced intensity conditioning (RIC) and hematopoietic stem cell transplantation (HSCT) from matched unrelated donors. The median age was 55 yr (range 11-68) and all but 15 patients received peripheral blood stem ce...

journal_title：Clinical transplantation

authors： Remberger M,Ringdén O,Hägglund H,Svahn BM,Ljungman P,Uhlin M,Mattsson J

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:In cardiac transplant recipients, long-term survival may be limited by transplant coronary artery disease (TxCAD). Hyperhomocysteinemia (Hhcy) has been associated with vascular disease and is common in transplant recipients. The objective of this study was to determine the relationship between fasting homocy...

journal_title：Clinical transplantation

authors： Miner SE,Cole DE,Evrovski J,Verma A,Daly PA,Ross HJ

更新日期：2001-08-01 00:00:00

abstract：:There is paucity in the data examining the differences in mycophenolate mofetil (MMF) dosing and outcomes among pediatric kidney transplant recipients (PKTX) between races. The aims of this study were as follows (i) to assess whether higher doses of MMF are being utilized in African American (AA) PKTX (ii) to determin...

journal_title：Clinical transplantation

authors： Jensen CJ,Shrivastava S,Taber DJ,Weimert NA,Shatat IF,Orak J,Chavin KD,Baliga PK

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Intra-abdominal fibromatosis often involves the mesentery root which is non-resectable by conventional surgery. Multivisceral transplant (MVT), as a potential cure to non-resectable fibromatosis, has rarely been reported and the prognosis is unknown. METHODS:Six patients who underwent MVT for intra-abdomina...

journal_title：Clinical transplantation

authors： Chi Z,Mangus RS,Kubal CA,Chen S,Lin J

更新日期：2018-03-01 00:00:00