The significance of residual tumor after preoperative pelvic irradiation for stage II endometrial carcinoma.

Abstract:

:The prognostic significance of residual endometrial carcinoma in the hysterectomy specimen after preoperative radiotherapy is controversial. Sixty-two patients with stage II endometrial carcinoma were treated with a standardized program of preoperative radiotherapy, followed in six weeks by an extrafascial hysterectomy. Twenty patients (32%) had no residual carcinoma in their hysterectomy specimens and 42 (68%) had residual carcinoma. There were no significant clinical, surgical, or pathologic differences between patients with or without residual carcinoma. Patients with no residual carcinoma had a 25% recurrence rate and a 53% actuarial five-year survival rate. Patients with residual carcinoma had a 21% recurrence rate and a 78% actuarial five-year survival rate. The presence of residual endometrial carcinoma in the hysterectomy specimen does not imply a compromised prognosis in patients with stage II endometrial carcinoma treated by the described method.

journal_name

Obstet Gynecol

authors

Larson DM,Copeland LJ,Gallager HS,Wharton JT,Gershenson DM,Rutledge FN

subject

Has Abstract

pub_date

1987-12-01 00:00:00

pages

916-9

issue

6

eissn

0029-7844

issn

1873-233X

journal_volume

70

pub_type

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