Use of the World Wide Web in research: randomization in a multicenter clinical trial of treatment for twin-twin transfusion syndrome.

Abstract:

OBJECTIVE:To describe the process involved in using the World Wide Web to coordinate a randomized, multicenter international trial of treatment for twin-twin transfusion syndrome. METHOD:A Web site was designed by members of the research team, a Web consultant, and a senior computer programmer. The original intent was to provide patient randomization only, but the Web site later was designed so that centers could download a data collection form. Data could be entered directly into the Web site and subsequently imported into a database at the coordinating center. EXPERIENCE:The Web site has been active for 3 years, with 13 participating centers and 31 patients enrolled. COMMENT:Use of the World Wide Web to coordinate an international, multicenter trial is an efficient method. Although there are many benefits, the most obvious is the capability to initiate and conduct a large international trial at minimal cost.

journal_name

Obstet Gynecol

authors

Dorman K,Saade GR,Smith H,Moise KJ Jr

doi

10.1016/s0029-7844(00)00978-9

subject

Has Abstract

pub_date

2000-10-01 00:00:00

pages

636-9

issue

4

eissn

0029-7844

issn

1873-233X

pii

S0029-7844(00)00978-9

journal_volume

96

pub_type

临床试验,杂志文章
  • Corpus luteum formation in the fetus.

    abstract::A well-developed corpus luteum was found at autopsy in a premature infant who died 26 hours post partum. Intrauterine pituitary-gonadal development and regulation are briefly reviewed and a possible mechanism of intrauterine fetal ovulation is presented. ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Miles PA,Penney LL

    更新日期:1983-04-01 00:00:00

  • Infant mortality and early postpartum discharge.

    abstract:OBJECTIVE:To assess additional risk of newborn death owing to early discharge. METHODS:This was a historical cohort study using Washington State linked birth certificates, death certificates, and hospital discharge records that covered 47,879 live births in 1989 and 1990. Logistic regression was used to assess risk of...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(00)00894-2

    authors: Malkin JD,Garber S,Broder MS,Keeler E

    更新日期:2000-08-01 00:00:00

  • The natural history of theca lutein cysts.

    abstract::The histories of 386 patients with untreated hydatidiform mole were reviewed to define the clinical aspects of accompanying theca lutein cysts. These cysts occurred in 102 patients (26.4%), with three patients experiencing cyst-related complications. Mean cyst size at diagnosis was 7.3 cm (3-20 cm), and did not correl...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Montz FJ,Schlaerth JB,Morrow CP

    更新日期:1988-08-01 00:00:00

  • Neonatal Morbidity and Maternal Complication Rates in Women With a Delivery Body Mass Index of 60 or Higher.

    abstract:OBJECTIVE:To investigate neonatal morbidity and maternal complication rates with delivery body mass index (BMI) 60 or greater. METHODS:This retrospective, multicenter cohort study included singleton pregnancies between 23 and 42 weeks of gestation from January 2005 to April 2016. Women with BMI 60 or greater were comp...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/AOG.0000000000002316

    authors: Kim T,Burn SC,Bangdiwala A,Pace S,Rauk P

    更新日期:2017-11-01 00:00:00

  • An unusual late presentation of imperforate hymen.

    abstract:BACKGROUND:The imperforate hymen is a rare gynecologic abnormality that may not be detected until the onset of menses, when hematocolpos causes symptoms due to an expanding pelvic mass. CASE:A 19-year-old woman had primary amenorrhea, originally misdiagnosed as müllerian agenesis. Because of a combination of late onse...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Sanders RM,Nakajima ST

    更新日期:1994-05-01 00:00:00

  • Use of a whole blood substitute, Fluosol-DA 20%, after massive postpartum hemorrhage.

    abstract::Two patients with severe postpartum hemorrhage refused blood product transfusion for religious reasons. The patients' hemoglobin level had dropped to 3.0% or less after operative intervention, and the cardiac indexes on transfer to the tertiary care center were 8.0 and 7.3 L/minute per m2, respectively. Each received ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Karn KE,Ogburn PL Jr,Julian T,Cerra FB,Hammerschmidt DE,Vercellotti G

    更新日期:1985-01-01 00:00:00

  • Association of Persistent Breech Presentation With External Cephalic Version Success.

    abstract:OBJECTIVE:To evaluate a possible correlation between a new variable-persistent breech presentation-and the success rate of external cephalic version (ECV). METHODS:This was a retrospective study of ECVs performed from January 2008 through January 2019 in an Israeli tertiary care hospital. The study group included all ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000004231

    authors: Lauterbach R,Bachar G,Ben-David C,Matanes E,Ginsberg Y,Beloosesky R,Ganem N,Weiner Z,Zipori Y

    更新日期:2021-02-01 00:00:00

  • Diminished bilirubin binding by the serum of pregnant women.

    abstract::Enzymatic peroxidase oxidation was used to study albumin-bilirubin binding in the serum of pregnant women, their term infants, and nonpregnant women. When the bilirubin titration curves were corrected for differing albumin concentrations in the three groups, the bilirubin binding of pregnant women was inferior to that...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Ritter DA,Gabai BR,Kenny JD

    更新日期:1985-05-01 00:00:00

  • Burkitt's lymphoma involving the ovary and jaw.

    abstract::Unilateral jaw and ovarian Burkitt's lymphoma occuring in an adult American female is reported. The patient was treated with a combination of surgery, radiation, and chemotherapy. The diagnosis, treatment, prognosis, and relapse patterns are briefly reviewed as they relate to the specialty of gynecology. ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Giere JW,Binder RA

    更新日期:1976-07-01 00:00:00

  • Recurrent streptococcal cellulitis complicating radical hysterectomy and radiation therapy.

    abstract::Reported is a rare complication of radical hysterectomy and radiation therapy, recurrent streptococcal cellulitis. Two patients had 14 episodes over a nine-year period, characterized by high fever and systemic toxicity. The streptococcal cellulitis was atypical in its presentation and its causative organism. The rash ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Chmel H,Hamdy M

    更新日期:1984-06-01 00:00:00

  • Evaluation of the small third-trimester fetus using the foam stability index test.

    abstract::The diagnostic effectiveness of the lecithin:sphingomyelin (L:S) ratio was compared with that of the quantitative amniotic fluid foam stability index (FSI) test in the prenatal evaluation of pregnancies associated with fetuses appropriately grown for gestational age (AGA) and with intrauterine growth retardation (IUGR...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Sher G,Statland BE,Knutzen VK

    更新日期:1981-09-01 00:00:00

  • A normal ultrasound does not obviate the need for amniocentesis in patients with elevated serum alpha-fetoprotein.

    abstract::Elevated levels of maternal serum alpha-fetoprotein (MSAFP) will identify a population at increased risk for specific congenital malformations, which are accurately diagnosed by amniotic fluid AFP and acetylcholinesterase. The risk for spontaneous abortion related to amniocentesis, combined with increasing confidence ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Drugan A,Zador IE,Syner FN,Sokol RJ,Sacks AJ,Evans MI

    更新日期:1988-10-01 00:00:00

  • Persistent placenta increta: a complication of conservative management of presumed placenta accreta.

    abstract:BACKGROUND:Recent reports have advocated conservative management rather than hysterectomy for placenta increta and its related conditions, placenta accreta and percreta. We report an unusual case of placenta increta in which initial conservative therapy for a presumed placenta accreta failed and hysterectomy was perfor...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0029-7844(96)00121-4

    authors: Davis JD,Cruz A

    更新日期:1996-10-01 00:00:00

  • Intracorporeal electromechanical tissue morcellation: a critical review and recommendations for clinical practice.

    abstract::Electromechanical morcellators have come under scrutiny with concerns about complications involving iatrogenic dissemination of both benign and malignant tissues. Although the rapidly rotating blade has resulted in morcellator-related vascular and visceral injuries, equally concerning are the multiple reports in the l...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/AOG.0000000000000448

    authors: Kho KA,Anderson TL,Nezhat CH

    更新日期:2014-10-01 00:00:00

  • Tranexamic acid treatment for heavy menstrual bleeding: a randomized controlled trial.

    abstract:OBJECTIVE:To assess the efficacy and safety of an oral formulation of tranexamic acid for the treatment of heavy menstrual bleeding. METHODS:Adult women with heavy menstrual bleeding (mean menstrual blood loss 80 mL or more per cycle) were enrolled in a double-blind, placebo-controlled study. After two pretreatment me...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/AOG.0b013e3181f20177

    authors: Lukes AS,Moore KA,Muse KN,Gersten JK,Hecht BR,Edlund M,Richter HE,Eder SE,Attia GR,Patrick DL,Rubin A,Shangold GA

    更新日期:2010-10-01 00:00:00

  • Body mass index and outcome of incontinence surgery.

    abstract:OBJECTIVE:To analyze the influence of body mass on the outcome of surgery for urinary incontinence. METHODS:Among 291 women operated on for stress incontinence, 187 (64%) were available for follow-up at 5 years. Eighty women had anterior colporrhaphy, 49 anterior colporrhaphy with needle suspension of the bladder neck...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(98)00513-4

    authors: Zivkovic F,Tamussino K,Pieber D,Haas J

    更新日期:1999-05-01 00:00:00

  • Subarachnoid phenol block for pain relief in gynecologic malignancy.

    abstract::One hundred and thirty-three subarachnoid phenol blocks were performed in 90 patients with intractable pain secondary to gynecologic cancer at the University of Iowa Hospitals in the period 1961 to 1975. Excellent to moderate pain relief was obtained in 77% of 117 evaluable blocks. Fifty-two percent of the blocks gave...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Lifshitz S,Debacker LJ,Buchsbaum HJ

    更新日期:1976-09-01 00:00:00

  • Effect of gonadotropin-releasing hormone agonist on a uterine arteriovenous malformation.

    abstract:BACKGROUND:The effect of gonadotropin-releasing hormone agonist (GnRHa) on uterine arteriovenous malformations (AVM) is not well known. CASE:A 37-year-old woman with a previous cesarean was diagnosed as having a uterine AVM after a spontaneous abortion with massive vaginal bleeding. The AVM decreased in size from 5.1 ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000191584.28717.2c

    authors: Morikawa M,Yamada T,Yamada H,Minakami H

    更新日期:2006-09-01 00:00:00

  • Abdominal wall repair with polypropylene mesh in pregnancy.

    abstract::A woman in her 34th week of gestation required emergency appendectomy for perforation, with postoperative wound dehiscence secondary to fasciitis and tension on the suture line. Polypropylene mesh was used to repair the abdominal wall. Fetal distress necessitated a cesarean section. The mother and child both survived ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Martin LF,Barry MG,Peeno DO,Fry DE

    更新日期:1985-07-01 00:00:00

  • Hemodynamic effects of head-down lithotomy position in patients with coronary artery disease.

    abstract::The hemodynamic effect of the head-down lithotomy (HDL) position was studied in 12 anesthetized patients with documented coronary artery disease. Data were collected in patients in supine position and then 10 minutes after placement in a 10-degree HDL position. Systolic arterial pressure (SP), mean arterial pressure (...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Kopman EA,Sandza JG Jr

    更新日期:1979-02-01 00:00:00

  • The effect of preterm birth on umbilical cord blood gases.

    abstract::Apgar scores are used routinely to assess early neonatal status, but are less accurate in the preterm neonate because of developmental immaturity. Attention has been directed to umbilical cord gases as a method of neonatal evaluation. Using a retrospective chart review of all viable preterm births (24-36 weeks' gestat...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Dickinson JE,Eriksen NL,Meyer BA,Parisi VM

    更新日期:1992-04-01 00:00:00

  • ACOG Practice Bulletin No. 111: Inherited thrombophilias in pregnancy.

    abstract::Inherited thrombophilias are associated with an increased risk of venous thromboembolism and also have been linked to adverse outcomes in pregnancy. However, there is limited evidence to guide screening for and management of these conditions in pregnancy. The purpose of this document is to review common thrombophilias...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e3181d9d82d

    authors:

    更新日期:2010-04-01 00:00:00

  • The accuracy of risk scores in predicting ovarian malignancy: a systematic review.

    abstract:OBJECTIVE:To perform a systematic review of the literature on the accuracy of prediction models in the preoperative assessment of adnexal masses. DATA SOURCES:Studies were identified through the MEDLINE and EMBASE databases from inception to March 2008. The MEDLINE search was performed using the keywords ["ovarian neo...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e318195ad17

    authors: Geomini P,Kruitwagen R,Bremer GL,Cnossen J,Mol BW

    更新日期:2009-02-01 00:00:00

  • Repair techniques for obstetric anal sphincter injuries: a randomized controlled trial.

    abstract:OBJECTIVE:To compare one-year outcomes of primary overlap versus end-to-end repair of the external anal sphincter after acute obstetric anal sphincter injury. METHODS:Women who sustained third-degree (3b = greater than 50% external anal sphincter thickness, 3c = internal sphincter injury) or fourth-degree (including a...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/01.AOG.0000218693.24144.bd

    authors: Fernando RJ,Sultan AH,Kettle C,Radley S,Jones P,O'Brien PM

    更新日期:2006-06-01 00:00:00

  • Initiation of human parturition. III. Fetal membrane content of prostaglandin E2 and F2alpha precursor.

    abstract::Unesterified arachidonic acid is the obligatory precursor of the prostaglandins (PG), PGF2alpha and PGE2. In order to ascertain whether or not the human fetal membranes could represent a storage site for prostaglandin(s) precursor, the fatty acid content of human fetal membranes was measured. Approximately 20% of the ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Schwarz BE,Schultz FM,Macdonald PC,Johnston JM

    更新日期:1975-11-01 00:00:00

  • Localization of blood vessels and qualitative assessment of blood flow in ovarian tumors.

    abstract:OBJECTIVE:To study the localization of blood vessels within a tumor and the shape of the flow curve as a method of assessing ovarian neoplasms. METHODS:We studied 39 patients with malignant tumors and 63 patients with benign ovarian tumors by means of vaginal color Doppler ultrasound, noting the localization of blood ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0029-7844(94)00293-m

    authors: Maly Z,Riss P,Deutinger J

    更新日期:1995-01-01 00:00:00

  • Serum relaxin in patients with hydatidiform mole.

    abstract::Human chorionic gonadotropin (hCG) is considered to be one of the factors that regulates relaxin secretion in humans. However, the secretory pattern of relaxin has not been evaluated in pregnancy complicated by hydatidiform mole, where circulating hCG levels are higher than in normal pregnancy. In the present study, r...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Seki K,Uesato T,Tabei T,Kato K

    更新日期:1986-03-01 00:00:00

  • Adverse Childhood Experiences Among Gynecology Patients With Chronic Pelvic Pain.

    abstract:OBJECTIVE:To compare adverse childhood experiences (ACEs) in women with chronic pelvic pain with a control group, and describe occurrence of specific ACEs in women with chronic pelvic pain. METHODS:This case-control study examined the relationship between history of ACEs, traumatic events occurring during childhood as...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000003533

    authors: Krantz TE,Andrews N,Petersen TR,Dunivan GC,Montoya M,Swanson N,Wenzl CK,Zambrano JR,Komesu YM

    更新日期:2019-11-01 00:00:00

  • Variables associated with postoperative deep venous thrombosis: a prospective study of 411 gynecology patients and creation of a prognostic model.

    abstract::Deep venous thrombosis is a major complication following gynecologic surgery. Assessing a patient's risk of developing deep venous thrombosis is important for patient selection and in choosing appropriate prophylactic methods. Four hundred eleven patients undergoing major gynecologic surgery were evaluated prospective...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Clarke-Pearson DL,DeLong ER,Synan IS,Coleman RE,Creasman WT

    更新日期:1987-02-01 00:00:00

  • Ethical analysis of the intrapartum management of pregnancy complicated by fetal hydrocephalus with macrocephaly.

    abstract::The intrapartum management of pregnancy complicated by fetal hydrocephalus with macrocephaly often confronts the physician with a complex array of moral obligations to both mother and fetus that may sometimes come into direct conflict. The authors analyze the component beneficence-based and autonomy-based obligations ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Chervenak FA,McCullough LB

    更新日期:1986-11-01 00:00:00