Preferential loss of GABAergic neurons in hypoxia-exposed neocortex slab cultures is attenuated by the NMDA receptor blocker D-2-amino-7-phosphonoheptanoate.

abstract：:Growth cones integrate a remarkably complex concert of chemical cues to guide axons to their appropriate destinations. Recent work suggests that integrins contribute to axon guidance by interacting with a wide range of extracellular molecules including axon guidance molecules, by mechanisms that are not fully understo...

journal_title：Brain research

authors： Lemons ML,Abanto ML,Dambrouskas N,Clements CC,Deloughery Z,Garozzo J,Condic ML

更新日期：2013-11-06 00:00:00

abstract：:Catecholamine-containing fibers have been examined in the cerebella of normal and hypocerebellar mutant mice using Falck-Hillarp and glyoxylic acid histofluorescence techniques. The amounts of norepinephrine and dopamine were also determined chemically in the same mutants. Green fluorescent fibers in cerebella of norm...

journal_title：Brain research

authors： Landis SC,Shoemaker WJ,Schlumpf M,Bloom FE

更新日期：1975-08-08 00:00:00

abstract：:The addition of L-glutamic acid (Glu) alone, both Glu and glycine (Gly) or Glu/Gly/spermidine (SPD) was effective in potentiating [3H]5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10- imine (MK-801) binding before equilibrium to an ion channel associated with the N-methyl-D-aspartate (NMDA) receptor complex in b...

journal_title：Brain research

authors： Yoneda Y,Enomoto R,Ogita K

更新日期：1994-02-14 00:00:00

abstract：:Studies were conducted to assess whether stimulation of dopamine receptors located in the globus pallidus might play a role in mediating the enhanced pallidal activity seen after systemic administration of dopamine agonists or D-amphetamine. Dopamine, applied iontophoretically, had modest effects on the activity of pa...

journal_title：Brain research

authors： Bergstrom DA,Walters JR

更新日期：1984-09-17 00:00:00

abstract：:When observing bistable stimuli, the percept can change in the absence of changes in the stimulus itself. When intermittently presenting a bistable stimulus, the number of perceptual alternations can increase or decrease, depending on the duration of the period that the stimulus is removed from screen between stimulus...

journal_title：Brain research

authors： Raemaekers M,van der Schaaf ME,van Ee R,van Wezel RJ

更新日期：2009-02-03 00:00:00

abstract：:Different mechanisms have been suggested to contribute to isoflurane-mediated neuroprotection. Previous studies have suggested that the protein Slit can abrogate neuronal death in mixed neuronal-glial cultures exposed to oxygen-glucose deprivation (OGD) and reperfusion (OGD/R). We hypothesized that isoflurane increase...

journal_title：Brain research

authors： Zhao XC,Zhang LM,Li Q,Tong DY,Fan LC,An P,Wu XY,Chen WM,Zhao P,Wang J

更新日期：2013-11-06 00:00:00

abstract：:The present study has shown that after intravenous injection of [125I]NGF the time-course of appearance of radioactivity in all organs studied with the exception of sympathetic and sensory ganglia, roughly paralleled that of the blood. The highest levels were reached immediately after injection, after which the radioa...

journal_title：Brain research

authors： Stoeckel K,Guroff G,Schwab M,Thoenen H

更新日期：1976-06-11 00:00:00

abstract：:Aging leads to many changes in the circadian timekeeping system, including reduced sensitivity to phase-resetting signals such as systemic administration of the serotonergic agonist, 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT). In previous studies, we observed an age-related decrease in 5-HT7 receptor binding s...

journal_title：Brain research

authors： Duncan MJ,Grear KE,Hoskins MA

更新日期：2004-05-15 00:00:00

abstract：:In non-neuronal cultures of cells dissociated from postnatal rat cerebellum astrocytes, identified by the presence of the marker protein glial fibrillary acidic protein (GFAP), displayed two distinct morphological forms. One class was stellate in shape with radially distributed fine processes, while the other class wa...

journal_title：Brain research

authors： Wilkin GP,Levi G,Johnstone SR,Riddle PN

更新日期：1983-11-01 00:00:00

abstract：:Many of our daily movements use visual information to guide our arms toward objects of interest. Typically, these visually guided movements involve first focusing our gaze on the intended target and then reaching toward the direction of our gaze. The literature on eye-hand coordination provides a great deal of evidenc...

journal_title：Brain research

authors： Gorbet DJ,Sergio LE

更新日期：2009-08-11 00:00:00

abstract：:In this study we investigated the functional connectivity in 23 Mild TBI (mTBI) patients with and without memory complaints using resting state fMRI in the sub-acute stage of injury as well as a group of control participants. Results indicate that mTBI patients with memory complaints performed significantly worse than...

journal_title：Brain research

authors： Sours C,Zhuo J,Janowich J,Aarabi B,Shanmuganathan K,Gullapalli RP

更新日期：2013-11-06 00:00:00

abstract：:The accumulation of amyloid-β (Aβ) peptides in the brain of Alzheimer disease patients is associated to cognitive deficit, increased oxidative stress, and alterations in the circadian rhythms. Brain-derived neurotrophic factor (BDNF) and Neurogranin (RC3), play an important role in the synaptic plasticity underlying m...

journal_title：Brain research

authors： Navigatore-Fonzo L,Castro A,Pignataro V,Garraza M,Casais M,Anzulovich AC

更新日期：2017-04-01 00:00:00

abstract：:A positive association between cardiorespiratory fitness (CRF) and white matter integrity has been consistently reported in older adults. However, it is unknown whether this association exists in adults over 80 with a range of chronic disease conditions and low physical activity participation, which can influence both...

journal_title：Brain research

authors： Tian Q,Simonsick EM,Erickson KI,Aizenstein HJ,Glynn NW,Boudreau RM,Newman AB,Kritchevsky SB,Yaffe K,Harris T,Rosano C,Health ABC study.

更新日期：2014-11-07 00:00:00

abstract：:Previous studies using the spin trapping agent N-tert-butyl-alpha-phenylnitrone (PBN) and the antioxidant vitamin E established the involvement of free radicals in kainic acid (KA)-induced neurotoxicity. In the present study, we examined the effects of the neuronal nitric oxide synthase (nNOS) inhibitor 7-nitroindazol...

journal_title：Brain research

authors： Gupta RC,Dettbarn WD

更新日期：2003-08-15 00:00:00

abstract：:Both enkephalin and 5-hydroxytryptamine (5-HT) have been implicated in neural mechanisms underlying the central control of respiration. In view of the role of the nuclei tractus solitarii (NTS) in respiratory regulation, we carried out a study in artificially ventilated, chloralose-anaesthetized cats of the effects of...

journal_title：Brain research

authors： Sessle BJ,Henry JL

更新日期：1985-02-18 00:00:00

abstract：:High levels of neurotensin/neuromedin N precursor mRNA, but few if any NT-positive perikarya have been detected in the dorsal subiculum of the adult rat or human hippocampus. This apparent discrepancy was tentatively ascribed to a lack of precursor mRNA translation or to a poor precursor posttranslational processing i...

journal_title：Brain research

authors： Nicot A,Bidard JN,Kitabgi P,Lhiaubet AM,Masuo Y,Palkovits M,Rostène W,Bérod A

更新日期：1995-12-08 00:00:00

abstract：:Rd mutant mice are visually blind but they maintain the ability of synchronising their circadian rhythms to the external light-dark cycles. We used immunocytochemical procedures to detect light-induced Fos expression in the rd mice retina. We found that Fos is expressed in the rd retina in an unattenuated pattern thro...

journal_title：Brain research

authors： Huerta JJ,Llamosas MM,Cernuda-Cernuda R,García-Fernández JM

更新日期：1999-07-10 00:00:00

abstract：:Neuronal expression of brain-derived neurotrophic factor (BDNF) has been implicated in the mechanism of infarct tolerance (resistance to stroke) (H. Yanamoto et al., Infarct tolerance accompanied enhanced BDNF-like immunoreactivity in neuronal nuclei, submitted to Brain Res.), a process that takes more than 7 days fol...

journal_title：Brain research

authors： Yanamoto H,Nagata I,Sakata M,Zhang Z,Tohnai N,Sakai H,Kikuchi H

更新日期：2000-03-24 00:00:00

abstract：:Retinal and tectal potentials to alternating gratings were recorded in pigeons raised monocularly deprived. Deprived eyes showed consistent myopia and anterior-posterior axis elongation. In addition, vitreal opacities were observed in 70% of the deprived eyes. In pigeons with vitreal opacities, a reduction of retinal ...

journal_title：Brain research

authors： Bagnoli P,Porciatti V,Francesconi W

更新日期：1985-07-15 00:00:00

abstract：:Accumulating evidence indicates that extensive microglia activation-mediated local inflammation contributes to neuronal injury in cerebral ischemia. We have previously shown that 4-(2-butyl-6, 7-dichloro-2-cyclopentyl-indan-1-on-5-yl) oxobutyric acid (DCPIB), a potent volume-regulated anion channel (VRAC) inhibitor, s...

journal_title：Brain research

authors： Han Q,Liu S,Li Z,Hu F,Zhang Q,Zhou M,Chen J,Lei T,Zhang H

更新日期：2014-01-13 00:00:00

abstract：:The effects of various nucleotides on the fast tetrodotoxin-sensitive (f-TTX-S) and the slow tetrodotoxin-resistant (s-TTX-R) sodium currents in rat dorsal root ganglion (DRG) neurons were investigated using the patch-clamp technique. Nucleoside triphosphates (NTPs; ATP, GTP, UTP and CTP) and nucleoside diphosphates (...

journal_title：Brain research

authors： Park SY,Kim HI,Shin YK,Lee CS,Park M,Song JH

更新日期：2004-05-01 00:00:00

abstract：:The pedunculopontine nucleus (PPN), the cholinergic arm of the reticular activating system (RAS), is known to modulate waking and rapid eye movement (REM) sleep. REM sleep decreases between 10 and 30 days postnatally in the rat, with the majority occurring between 12 and 21 days. We investigated the possibility that c...

journal_title：Brain research

authors： Good CH,Bay KD,Buchanan R,Skinner RD,Garcia-Rill E

更新日期：2007-01-19 00:00:00

abstract：:Migraine and anxiety disorders are frequently co-morbid with balance disorders. This study examined the relative distribution of subtypes of serotonin (5-HT) receptor in the inner ear of monkeys and rats. Most vestibular ganglion cells were immunoreactive for 5-HT(1B) and 5-HT(1D) receptors in macaques and rats. In th...

journal_title：Brain research

authors： Ahn SK,Balaban CD

更新日期：2010-07-30 00:00:00

abstract：:The early electrophysiological phenomena linked to systemic inflammation are largely underexplored. We developed here local field analyses to detect prodromal oscillatory abnormalities. We identified early band-specific patterns in local field potential recorded from freely-moving rats injected intraperitoneally with ...

journal_title：Brain research

authors： Mamad O,Islam MN,Cunningham C,Tsanov M

更新日期：2018-02-15 00:00:00

abstract：:Long-term memory formation for passive-avoidance learning in the day-old chick is known to have two distinct time windows of protein synthesis (F.M. Freeman, S.P.R. Rose, A.B. Scholey, 1995. Two time windows of anisomycin-induced amnesia for passive-avoidance training in the day-old chick. Neurobiol. Learn. Mem. 63, 2...

journal_title：Brain research

authors： Freeman FM,Young IG

更新日期：2000-05-12 00:00:00

abstract：:The present investigations were designed to assess the effect of the serotoninergic system on luteinizing hormone (LH) and LH-releasing hormone (LH-RH) secretion in female rats aged 14 and 30 days. The administration of 5-hydroxytryptophan (5-HTP; 75 mg/kg i.p.) increased hypothalamic serotonin (5-HT) concentrations i...

journal_title：Brain research

authors： Arias P,Szwarcfarb B,de Rondina DC,Carbone S,Sverdlik R,Moguilevsky JA

更新日期：1990-07-16 00:00:00

abstract：:During functional spinal neural network activity motoneurons receive massive synaptic excitation and inhibition, and their membrane conductance increases considerably - they are switched to a high-conductance state. High-conductance states can substantially alter response properties of motoneurons. In the present stud...

journal_title：Brain research

authors： Grigonis R,Guzulaitis R,Buisas R,Alaburda A

更新日期：2016-10-01 00:00:00

abstract：:The current study revisited the question of whether there are brain mechanisms specific to divided attention that differ from those used in selective attention. Increased neuronal activity required to simultaneously process two stimulus dimensions as compared with each separate dimension has often been observed, but r...

journal_title：Brain research

authors： Hahn B,Wolkenberg FA,Ross TJ,Myers CS,Heishman SJ,Stein DJ,Kurup PK,Stein EA

更新日期：2008-06-18 00:00:00

abstract：:Electrolytic lesions were placed in the medial cerebellar nucleus in tree shrews (Tupaia glis) or in fibers issuing from this nucleus. Brains and spinal cords were processed according to Fink-Heimer procedure following survival times of 2-7 days. In control animals lesions were placed in the cerebellar cortex and, in ...

journal_title：Brain research

authors： Ware CB,Mufson EJ

更新日期：1979-08-10 00:00:00

abstract：:The visual Wulst (VW) in the avian telencephalon is thought to be an avian equivalent of the mammalian striate cortex. Effects of electrical stimulation of VW were studied in the isthmo-optic nucleus (ION) of the Japanese quail by extracellular recording. Most ION neurons examined were activated by VW stimulation, and...

journal_title：Brain research

authors： Uchiyama H,Matsutani S,Watanabe M

更新日期：1987-03-17 00:00:00