Interferon-associated retinopathy in a patient with metastatic melanoma.

Abstract:

:We present the unusual case of a 35 year-old woman with stage IV melanoma and widespread metastases, who was undergoing treatment with interferon alpha-2b and who presented with interferon-associated retinopathy. The patient, who had been taking interferon treatment for three months, complained of a sudden loss of visual acuity in the left eye. An ocular examination revealed multiple cotton wool spots along the retina and macular involvement. Interferon treatment was suspended. Although rare, retinopathy represents a potentially serious adverse effect of interferon treatment. Although normally patients are asymptomatic, complications derived of its use may arise, which can lead to significant visual impairment. We therefore suggest that before initiating treatment with this drug, patients should be informed of its potential ocular risks, and that regular eye examinations are conducted along with the treatment.

journal_name

Arq Bras Oftalmol

authors

Borrego-Sanz L,Sáenz-Francés F,Fernández-Tresguerres MF,Jiménez-Santos M,Donate-López J

doi

10.5935/0004-2749.20140080

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

321-323

issue

5

eissn

0004-2749

issn

1678-2925

pii

S0004-27492014000500321

journal_volume

77

pub_type

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