Abstract:
:We present the unusual case of a 35 year-old woman with stage IV melanoma and widespread metastases, who was undergoing treatment with interferon alpha-2b and who presented with interferon-associated retinopathy. The patient, who had been taking interferon treatment for three months, complained of a sudden loss of visual acuity in the left eye. An ocular examination revealed multiple cotton wool spots along the retina and macular involvement. Interferon treatment was suspended. Although rare, retinopathy represents a potentially serious adverse effect of interferon treatment. Although normally patients are asymptomatic, complications derived of its use may arise, which can lead to significant visual impairment. We therefore suggest that before initiating treatment with this drug, patients should be informed of its potential ocular risks, and that regular eye examinations are conducted along with the treatment.
journal_name
Arq Bras Oftalmoljournal_title
Arquivos brasileiros de oftalmologiaauthors
Borrego-Sanz L,Sáenz-Francés F,Fernández-Tresguerres MF,Jiménez-Santos M,Donate-López Jdoi
10.5935/0004-2749.20140080subject
Has Abstractpub_date
2014-10-01 00:00:00pages
321-323issue
5eissn
0004-2749issn
1678-2925pii
S0004-27492014000500321journal_volume
77pub_type
杂志文章abstract::Fungal endophthalmitis is a rare condition often associated with poor prognosis. We present a case of postoperative acute fungal endophthalmitis caused by the yeast-like fungus Stephanoascus ciferrii (Candida ciferrii). The fungus was resistant to fluconazole, voriconazole, and amphotericin B but susceptible to caspof...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20170048
更新日期:2017-06-01 00:00:00
abstract::We report the case of an 11-year-old girl with sickle cell disease who presented to the emergency room after being hit by a mud pie in the left frontal region. Examination evidenced left eye proptosis, eyelid swelling, reduced visual acuity and afferent pupillary defect, without any inflammatory signs such as fever, h...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492008000200024
更新日期:2008-03-01 00:00:00
abstract:PURPOSE:To evaluate whether any topical anti-glaucoma medications increase the risk of lacrimal drainage system obstruction or whether the presence of preservatives alone is sufficient to generate obstruction. METHODS:This nested case-control study compared a group of patients with lacrimal duct obstruction who receiv...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20180095
更新日期:2018-11-01 00:00:00
abstract:PURPOSE:To evaluate the effectiveness in in-traocular pressure reduction and safety of micropulse trans-scleral diode cyclophotocoagulation in refractory glaucoma. METHODS:We prospectively evaluated a case series of 21 eyes of 21 consecutive patients with refractory glaucoma treated with micropulse transscleral diode ...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20190076
更新日期:2019-06-27 00:00:00
abstract:PURPOSE:Analysis of the relevance of preoperative evaluation to prevent adverse clinical events, pre- and postoperative, on cataract surgery. METHODS:The study includes 1254 patients submitted to cataract surgery at the Instituto da Catarata do Departamento de Oftalmologia da UNIFESP - EPM, in the period of Jan - Dec ...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492007000400014
更新日期:2007-07-01 00:00:00
abstract:PURPOSE:To investigate the distribution of axial length, anterior chamber depth, lens thickness, vitreous chamber depth, and central corneal thickness in children at different age groups. METHODS:We studied 364 eyes in 182 children with ages between 1 and 12 years. Axial length, anterior chamber depth, lens thickness,...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20140039
更新日期:2014-05-01 00:00:00
abstract::A 26 years old female patient was examined twenty-four hours after observing laser-induced plasma formation in a process of nanoparticle production complaining of bilateral central scotoma. The ophthalmologic evaluation included dilated fundus observation, fluorescein angiography, and optical coherence tomography (OCT...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492013000500015
更新日期:2013-10-01 00:00:00
abstract::To report a case of aberrant regeneration followed by acute palsy of the oculomotor nerve caused by intracranial aneurysm. A 59-year-old patient was attended in February 2006 complaining of headache with diplopia and blepharoptosis in the right eye. At the external ocular motility exam. Aduction, supraduction and infr...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492008000300028
更新日期:2008-05-01 00:00:00
abstract::We describe a case of keratomycosis caused by Arthographis kalrae after excimer laser keratomileusis. A 38-year-old female developed stromal keratitis eight weeks after refractive surgery. She developed severe corneal stromal infiltration and mild anterior segment inflammation, which could not be treated with topical ...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 信件
doi:10.5935/0004-2749.20200004
更新日期:2020-01-01 00:00:00
abstract:PURPOSE:To investigate whether the time interval between type 2 diabetes mellitus (DM) diagnosis and the first fundoscopic examination is related with the presence and the severity of diabetic retinopathy (DR) observed. METHODS:A survey of 105 type 2 DM patients referred to ophthalmologic evaluation in the "Hospital d...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492010000300006
更新日期:2010-05-01 00:00:00
abstract:Purpose::To compare central corneal thickness (CCT) measurements of healthy individuals obtained with ultrasonic pachymetry (UP) and non-contact specular microscopy (NCSM). Method::In total, 148 eyes of 74 subjects with no ocular or systemic diseases were included in the study. Central corneal thickness measurements o...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20160089
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:The purpose of this study was to identify, according to an systematic review, the best treatment for acute retinal necrosis. METHODS:Following the methodologic guidance of the Cochrane Collaboration and its editorial subgroup "Eye and Vision Group", using search strategy for study identification, articles abou...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章,评审
doi:10.1590/s0004-27492005000400009
更新日期:2005-07-01 00:00:00
abstract:PURPOSES:To evaluate the retina nerve fiber layer by laser polarimetry in patients in chronic use of chloroquine. METHODS:Forty-four eyes of twenty-two patients were studied. These were in use of chloroquine due to rheumatic diseases during at least one year. As a control group, twenty patients without use of chloroqu...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492005000200008
更新日期:2005-03-01 00:00:00
abstract:PURPOSE:To describe an outbreak of Pseudomonas aeruginosa endophthalmitis post cataract surgery. Clinical findings, treatment and outcome are discussed. METHODS:Clinical charts review of forty-five patients treated for endophthalmitis in a two-day period. The patients underwent primary vitrectomy, anterior chamber irr...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492012000500010
更新日期:2012-10-01 00:00:00
abstract:PURPOSE:To evaluate the first three years of The Amazon Ocular Oncology Center, the first ocular cancer center in the North of Brazil. METHODS:Here, we report patient information including patients' age, gender, diagnosis, treatment, and city of origin. RESULTS:Two hundred and twenty-one patients were included on thi...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20190024
更新日期:2019-03-01 00:00:00
abstract::Ocular inflammation is one of the leading causes of blindness and loss of vision. Human uveitis is a complex and heterogeneous group of diseases characterized by inflammation of intraocular tissues. The eye may be the only organ involved, or uveitis may be part of a systemic disease. A significant number of cases are ...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章,评审
doi:10.1590/s0004-27492012000200016
更新日期:2012-03-01 00:00:00
abstract::Abnormalities in visual processing caused by visual deprivation or abnormal binocular interaction may induce amblyopia, which is characterized by reduced visual acuity. Occlusion therapy, the conventional treatment, requires special attention as occlusion of the fellow normal eye may reduce its visual acuity and impai...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章,评审
doi:10.5935/0004-2749.20160099
更新日期:2016-09-01 00:00:00
abstract:PURPOSE:To describe costs and outcomes of phacoemulsification for cataracts performed by ophthalmology residents. METHODS:We obtained medical records from patients operated on in 2011 by third year residents (R3) using phacoemulsification (n=576). Our expenses estimation included professionals' and hospital costs (fee...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20200059
更新日期:2020-06-01 00:00:00
abstract::Ichthyosis follicular, alopecia, and photophobia (IFAP) syndrome is a rare disease, with possible X-linked mode of inheritance. The patient presented with ocular findings of photophobia, corneal scarring and erosions, superficial and deep corneal vascularization and myopia. He was treated with artificial tears and pun...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492011000100013
更新日期:2011-01-01 00:00:00
abstract:Purpose::To analyze the indications and types of eye removal at Latin America's highest-volume ophthalmic reference center in São Paulo, Brazil. Methods::A retrospective analysis was conducted of surgical pathological reports in the electronic database of the Ophthalmology Department of the Universidade Federal de São...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20170054
更新日期:2017-07-01 00:00:00
abstract::The practical advantages of quantifying an angle by a ratio of linear lengths instead of arcs of circles has led to the definition of the prism-diopter, a conventional unity for numbering prisms and measuring strabismic deviations. However, a major inconvenience of using prism-diopter unities to express angular measur...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.5935/0004-2749.20140070
更新日期:2014-10-01 00:00:00
abstract::Orbital emphysema is the abnormal presence of air in the orbit. Occurrence in the absence of orbital fracture is rare. We report a case of a 40-year-old female presenting unilateral orbital emphysema after vigorous nose blowing. She developed sudden visual loss as a result of elevated intraocular pressure and urgent t...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492009000200024
更新日期:2009-03-01 00:00:00
abstract:PURPOSE:To study the deformation response of three distinct contact lenses with known structures, which served as corneal models, under different chamber pressures using ultra-high-speed (UHS) Scheimpflug imaging. METHODS:Three hydrophilic contact lenses were mounted on a sealed water chamber with precisely adjustable...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492013000500005
更新日期:2013-10-01 00:00:00
abstract:PURPOSE:To estimate the occurrence of adverse effects associated with the use of botulinum toxin by performing a systematic review and meta-analysis. METHODS:A systematic literature search of MEDLINE and Cochrane Library was conducted until September 2007. The occurrence of the adverse effects was estimated of the rel...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章,meta分析,评审
doi:10.1590/s0004-27492008000600027
更新日期:2008-11-01 00:00:00
abstract:PURPOSE:To evaluate dacrycystographic examination in patients with suspicion of lacrimal apparatus obstruction. METHODS:A retrospective study was performed to evaluate dacryocystographies of 100 adults suspected of nasolacrimal duct obstruction at the "Faculdade de Medicina de Botucatu-UNESP". The data were submitted ...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492005000100016
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To evaluate the ophthalmic artery hemodynamics in patients with chronic heart failure. METHODS:Doppler parameters of ophthalmic artery of 18 patients with chronic heart failure in different stages of the disease were compared with 21 healthy volunteers (control group). These parameters were also correlated wit...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492011000500003
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:To evaluate the epidemiology of superficial corneal foreign body. METHODS:Patients who were seen at the Emergency Service of the Federal University of São Paulo, from April/05 to June/05, were screened and those with superficial corneal foreign body were interviewed. Data regarding gender, age, occupation, emp...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492008000200004
更新日期:2008-03-01 00:00:00
abstract::The optical coherence tomography (OCT) and indocyanine green angiography (ICGA) findings of a 58-year-old male with acute syphilitic posterior placoid chorioretinitis are reported herein. Best-corrected visual acuity was 20/150 in the right eye (OD) and 20/30 in the left eye (OS) at presentation. On funduscopy, there ...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492009000600019
更新日期:2009-11-01 00:00:00
abstract::We report the case of a seven year-old male patient, born at term without any perinatal complications, referred to the Retina/Vitreous Service for diagnostic elucidation. He had a history of progressive visual acuity loss on his left eye that started four years ago. On examination, he had decreased corneal diameter an...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章
doi:10.1590/s0004-27492011000400014
更新日期:2011-07-01 00:00:00
abstract::In this systematic review, we evaluated studies involving adjuvant and primary topical treatment for ocular surface squamous neoplasia (OSSN). The findings were: (i) adjuvant 5-fluorouracil (5-FU) reduces the risk of relapse after surgical excision with mild side effects [level Ib, grade of recommendation (GR) A]. (ii...
journal_title:Arquivos brasileiros de oftalmologia
pub_type: 杂志文章,评审
doi:10.5935/0004-2749.20170032
更新日期:2017-03-01 00:00:00