A case of recurrent keratitis caused by Paecilomyces lilacinus and treated by voriconazole.

Abstract:

:We describe here a case of a 21-year-old woman who presented with low visual acuity, pain, and hyperemia in the left eye for 45 days. Her eye had extensive corneal infiltrate, with melting and a central perforation that was glued with cyanoacrylate, but with Seidel (+). She underwent tectonic corneal transplantation, and anterior chamber lavage with subconjunctival infiltration with voriconazole, as well as intracameral injections of amphotericin B. Laboratory tests revealed Paecilomyces lilacinus as the infectious agent. The patient was then maintained with oral voriconazole and eye drops for three months, after which the infection was considered cured. However, in the sixth postoperative month she presented with endothelial rejection, and two weeks later signs of recurrence of the fungal infection. She was treated with two further washes of the anterior chamber and subconjunctival injection of voriconazole, followed by intravenous voriconazole that was replaced with drops after ten days. The infection initially worsened, but then regressed, and at last follow-up, the patient was still infection-free.

journal_name

Arq Bras Oftalmol

authors

Gracitelli CPB,Ferrar PV,Pereira CAP,Hirai FE,de Freitas D

doi

10.5935/0004-2749.20190031

subject

Has Abstract

pub_date

2019-03-01 00:00:00

pages

152-154

issue

2

eissn

0004-2749

issn

1678-2925

pii

S0004-27492019000200152

journal_volume

82

pub_type

信件
  • Clinical and epidemiological characteristics of patients with uveitis in an emergency eye care center in Brazil.

    abstract:PURPOSE:To analyze the clinical and epidemiological characteristics of patients with uveitis in an emergency eye care center. METHODS:We conducted a prospective, observational study of patients with active uveitis admitted between May 2012 and July 2012 to an emergency eye care center. RESULTS:The majority of patient...

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  • [Refractional astigmatism prevalence and its relationship with grating acuity in children 2 to 36 months of age].

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  • [Noncompliance with drug therapy for glaucoma].

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    authors: Castro AN,Mesquita WA

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  • [Optical coherence tomography to evaluate peripapillary retinal nerve fiber layer in chloroquine patients].

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    doi:10.5935/0004-2749.20150014

    authors: Suzuki AC,Zacharias LC,Tanaka T,Rocha DN,Takahashi WY

    更新日期:2015-01-01 00:00:00

  • [Adverse effects associated with facial application of botulinum toxin: a systematic review with meta-analysis].

    abstract:PURPOSE:To estimate the occurrence of adverse effects associated with the use of botulinum toxin by performing a systematic review and meta-analysis. METHODS:A systematic literature search of MEDLINE and Cochrane Library was conducted until September 2007. The occurrence of the adverse effects was estimated of the rel...

    journal_title:Arquivos brasileiros de oftalmologia

    pub_type: 杂志文章,meta分析,评审

    doi:10.1590/s0004-27492008000600027

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  • [Comparison between the postoperative results of triple procedure and combined penetrating keratoplasty/transsclerally sutured posterior chamber lens implantation].

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    journal_title:Arquivos brasileiros de oftalmologia

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    authors: Leão DM,de Sousa LB

    更新日期:2006-07-01 00:00:00

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    pub_type: 杂志文章

    doi:10.5935/0004-2749.20140099

    authors: Geraissate JC,Yamamoto RE,Isaac DL,Ávila MP

    更新日期:2014-11-01 00:00:00

  • Impact of chamber pressure and material properties on the deformation response of corneal models measured by dynamic ultra-high-speed Scheimpflug imaging.

    abstract:PURPOSE:To study the deformation response of three distinct contact lenses with known structures, which served as corneal models, under different chamber pressures using ultra-high-speed (UHS) Scheimpflug imaging. METHODS:Three hydrophilic contact lenses were mounted on a sealed water chamber with precisely adjustable...

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    authors: Correia FF,Ramos I,Roberts CJ,Steinmueller A,Krug M,Ambrósio R Jr

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    abstract::Nature has always provided an unlimited source of biologically-active compounds. Since the beginning of mankind, humans have sought resources in fauna and flora to treat eye diseases. However, it was only after the Industrial Revolution that extracts of plants and substances of animal origin could be used safely, as h...

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    更新日期:2005-07-01 00:00:00

  • [Avulsed retinal vessels].

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  • [Eyelid ectropium prevalence and carriers characteristics in a population from the Center-Western region of São Paulo State].

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    doi:

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    更新日期:2009-01-01 00:00:00

  • [Posterior scleritis: clinical features, systemic association, treatment and evolution of 23 patients].

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  • [Correction factor for individuals with accommodative capacity based on automated refractor].

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