Clinical application of remifentanil in local anesthesia for tumor resection in functional brain area.

Abstract:

OBJECTIVE:The aim of this study was to investigate clinical application of remifentanil in local anesthesia for resection of tumors in functional brain area. PATIENTS AND METHODS:Twenty-four patients were randomly divided into two groups: control group and remifentanil group. In remifentanil group remifentanil was infused intravenously with micro pump in 0.05-0.1 µg·kg-1·min-1. The hemodynamic changes and complications during operation were monitored. RESULTS:The satisfactory degree for surgical procedure was evaluated. The surgery of two groups could be completed in a conscious state. Mean artery pressure (MAP), heart rate (HR) in remifentanil group during opening or closing skull or intra- cranial period were significantly lower than control group (p < 0.05). There were no conspicuous complications in two groups such as respiratory depression, nausea, vomitting and dysphoria. Satisfaction rate of remifentanyl group was significantly higher than control group (p < 0.05). CONCLUSIONS:Awake brain tumor surgery could be completed in rational use of remifentanil on the base of good local anesthesia, and hemodynamics were stable and the patients were well tolerated.

authors

Cao SE,Gao BQ,Zhang YQ,Yang SM,Liu GZ,Zhang XR

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

3212-6

issue

21

eissn

1128-3602

issn

2284-0729

journal_volume

18

pub_type

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