Abstract:
:Myocardial thallium-201 scintigraphy is being increasingly employed as a method for assessing the efficacy of coronary reperfusion in acute myocardial infarction. New thallium uptake after intracoronary tracer administration after successful recanalization indicates that nutrient blood flow has been successfully restored. One may also presume that some myocardial salvage occurred if thallium administered in this manner is transported intracellularly by myocytes with intact sarcolemmal membranes. However, if one injects thallium by way of the intracoronary route immediately after reperfusion, the initial uptake of thallium in reperfused myocardium may predominantly represent hyperemic flow and regional thallium counts measured may not be proportional to the mass of viable myocytes. When thallium is injected intravenously during the occlusion phase the degree of redistribution after thrombolysis is proportional to the degree of flow restoration and myocardial viability. When thallium is injected for the first time intravenously immediately after reperfusion, an overestimation of myocardial salvage may occur because of "excess" thallium uptake in the infarct zone consequent to significant hyperemia. Another approach to myocardial thallium scintigraphy in patients undergoing thrombolytic therapy is to administer two separate intravenous injections before and 24 hours or later after treatment. Clinical studies have demonstrated that the improvement in defect size on serial images predicts improvement in regional function and patency of the infarct-related vessel. Finally, patients with acute myocardial infarction who receive intravenous thrombolytic therapy are candidates for predischarge exercise thallium-201 scintigraphy for risk stratification and detection of residual ischemia.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
J Am Coll Cardioljournal_title
Journal of the American College of Cardiologyauthors
Beller GAdoi
10.1016/s0735-1097(87)80062-1subject
Has Abstractpub_date
1987-03-01 00:00:00pages
661-8issue
3eissn
0735-1097issn
1558-3597pii
S0735-1097(87)80062-1journal_volume
9pub_type
杂志文章abstract:OBJECTIVES:The purpose of this study was to investigate the impact of the chordae tendineae force distribution on systolic mitral leaflet geometry and mitral valve competence in vitro. BACKGROUND:Functional mitral regurgitation is caused by changes in several elements of the valve apparatus. Interaction among these ha...
journal_title:Journal of the American College of Cardiology
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doi:10.1016/s0735-1097(98)00627-5
更新日期:1999-03-01 00:00:00
abstract:OBJECTIVES:This study was designed to ascertain whether cardiodepressive mediators released after ischemia originate from coronary endothelial cells. BACKGROUND:Endothelial cells modulate myocardial contractility under physiologic conditions. Few data are available describing the role of coronary endothelial cells on ...
journal_title:Journal of the American College of Cardiology
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doi:10.1016/s0735-1097(97)82760-x
更新日期:1997-05-01 00:00:00
abstract:OBJECTIVES:This study was designed to determine whether imaging myocardial edema would identify acute myocardial ischemia before irreversible injury takes place. BACKGROUND:Early identification of acute myocardial ischemia is a diagnostic challenge. METHODS:We studied 15 dogs with serial T(2)-weighted and cine imagin...
journal_title:Journal of the American College of Cardiology
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doi:10.1016/j.jacc.2008.10.065
更新日期:2009-04-07 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/j.jacc.2008.08.024
更新日期:2008-11-11 00:00:00
abstract:OBJECTIVES:We developed an automatic quantitative algorithm for the measurement of regional myocardial wall motion and wall thickening from three-dimensional gated technetium-99m sestamibi myocardial perfusion single-photon emission computed tomographic images. BACKGROUND:The algorithm measures the motion of the three...
journal_title:Journal of the American College of Cardiology
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更新日期:1997-11-01 00:00:00
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journal_title:Journal of the American College of Cardiology
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doi:10.1016/j.jacc.2005.11.083
更新日期:2006-05-16 00:00:00
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journal_title:Journal of the American College of Cardiology
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更新日期:2020-12-15 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/j.jacc.2015.08.862
更新日期:2015-11-03 00:00:00
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journal_title:Journal of the American College of Cardiology
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更新日期:1999-07-01 00:00:00
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journal_title:Journal of the American College of Cardiology
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更新日期:2000-02-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,meta分析
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更新日期:2018-06-05 00:00:00
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更新日期:1993-04-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2014-04-01 00:00:00
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journal_title:Journal of the American College of Cardiology
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doi:10.1016/j.jacc.2007.03.069
更新日期:2007-10-02 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jacc.2018.05.075
更新日期:2018-09-11 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/s0735-1097(83)80114-4
更新日期:1983-04-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2013-07-30 00:00:00
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journal_title:Journal of the American College of Cardiology
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更新日期:2020-12-22 00:00:00
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更新日期:2002-01-16 00:00:00
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更新日期:1991-02-01 00:00:00
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journal_title:Journal of the American College of Cardiology
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更新日期:2000-04-01 00:00:00
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更新日期:2016-07-19 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
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更新日期:2012-11-20 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
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更新日期:1999-05-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1992-02-01 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0735-1097(00)00888-3
更新日期:2000-09-01 00:00:00
abstract::Both obesity and atrial fibrillation (AF) are increasing in epidemic proportions, and both increase the prevalence of cardiovascular disease events. Obesity has adverse effects on cardiovascular hemodynamics and cardiac structure and function, and increases the prevalence of AF, partly related to electroanatomic remod...
journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,评审
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更新日期:2017-10-17 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.jacc.2009.01.046
更新日期:2009-04-28 00:00:00
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journal_title:Journal of the American College of Cardiology
pub_type: 杂志文章
doi:10.1016/0735-1097(94)90144-9
更新日期:1994-11-15 00:00:00