Abstract:
PURPOSE:To evaluate whether cost, insurance prior authorization, pregnancy considerations, and subspecialty practice lead to changes in therapeutic decisions among uveitis and retina specialists in the treatment of intermediate and posterior uveitis. DESIGN:Prospective cross-sectional study. METHODS:A total of 934 uveitis and retina specialists across the United States were surveyed via e-mail regarding their choice in long-term therapy for 3 hypothetical patients with uveitic conditions (Behçet disease, birdshot retinochoroiditis, and intermediate uveitis). Respondents were asked to select first- and second-choice therapies and then reselect first and second choices assuming cost of all options was equal to the patient and there would be no issues with insurance prior authorization. In 1 case, they were additionally asked for their treatment preferences if the patient desired a pregnancy. Outcomes of interest were differences in therapy choice based on cost/prior authorization, pregnancy, and subspecialty practice. RESULTS:One hundred and six respondents (11.3%) completed the survey; 44 were uveitis specialists and 62 retina specialists. Cost and prior authorization affected the therapy choices of uveitis specialists treating ocular Behçet disease (P = .008). Uveitis specialists and retina specialists differed in their first choice in therapy for each vignette when cost and prior authorization were equalized (P = .0018, P = .0049, and P = .0156). Both uveitis specialists and retina specialists changed their therapeutic choices for intermediate uveitis when pregnancy was a consideration (P = .00001 for uveitis specialists, P = .0044 for retina specialists). CONCLUSIONS:Physician decision making in intermediate and posterior uveitis is affected by cost and prior authorization concerns, pregnancy considerations, and subspecialty practice.
journal_name
Am J Ophthalmoljournal_title
American journal of ophthalmologyauthors
Ozzello DJ,Palestine AGdoi
10.1016/j.ajo.2014.10.015subject
Has Abstractpub_date
2015-02-01 00:00:00pages
213-20.e3issue
2eissn
0002-9394issn
1879-1891pii
S0002-9394(14)00663-1journal_volume
159pub_type
杂志文章abstract:PURPOSE:To examine changes in the outer layer of the detached retina in rhegmatogenous retinal detachment (RRD) and central serous chorioretinopathy (CSC) with optical coherence tomography (OCT). DESIGN:Retrospective, observational case series. METHODS:Fifteen eyes (15 patients) with RRD and 16 eyes (16 patients) wit...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2008.09.030
更新日期:2009-03-01 00:00:00
abstract::We used specular microscopy to investigate corneal endothelial changes after excimer laser photorefractive keratectomy. Twenty patients (26 eyes) underwent photorefractive keratectomy for the correction of myopia. The central cornea endothelium of each eye was observed preoperatively and one month postoperatively. Six...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)73467-1
更新日期:1993-12-15 00:00:00
abstract::We studied the bilateral intraocular pressure lowering effect of long-term unilateral timolol maleate 0.5% in 30 patients in whom early primary open-angle glaucoma had recently been diagnosed. A significant intraocular pressure reduction was found in the untreated fellow eyes (21.9 mm Hg from 26.4 mm Hg at baseline) (...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(87)90169-3
更新日期:1987-12-15 00:00:00
abstract:PURPOSE:To determine whether the frequency doubling perimeter (FDP) can grade glaucomatous visual function loss in a clinically relevant manner. Sinusoidal gratings < 1 cpd that undergo counterphase flicker > 15 Hz appear to have twice as many bands of light, a phenomenon referred to as the "frequency doubling illusion...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(98)00047-6
更新日期:1998-06-01 00:00:00
abstract::Vitreous surgery techniques can be used to remove epiretinal tissue associated with various ocular conditions when this tissue covers, distorts, or detaches the macula and causes visual loss. Because the postoperative visual acuity is often between 6/9 (20/30) and 6/30 (20/100), we usually operate on eyes with preoper...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)74654-9
更新日期:1981-11-01 00:00:00
abstract::Six patients with retinal detachment associated with the acute retinal necrosis syndrome were treated by the combination of vitrectomy, gas injection, and laser photocoagulation. The retinas were successfully reattached in each patient with one operation. Five of the patients achieved a visual acuity of 20/200 or bett...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(88)90878-1
更新日期:1988-10-15 00:00:00
abstract:PURPOSE:To investigate the effect of posterior subtenon injections of corticosteroids on intraocular pressure in a variety of ocular diseases. METHODS:We retrospectively analyzed 202 consecutive posterior subtenon corticosteroid injections (148 of methylprednisolone acetate, 80 mg, and 54 of triamcinolone acetonide, 4...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(99)80085-3
更新日期:1998-02-01 00:00:00
abstract:PURPOSE:To evaluate the effect of contact lens (CL) wear and visual display terminal (VDT) work on the ocular surface and tear functions. DESIGN:Prospective case-control study. METHODS:Sixty-nine CL wearers (45 women and 24 men; mean age, 35.2 ± 7.3 years), and 102 age- and sex-matched non-CL wearers were enrolled in...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2011.05.025
更新日期:2011-12-01 00:00:00
abstract::An ultrastructural study of Bruch's membrane in 68 human eyes including at least five individuals from each of ten decades of life showed that changes began in the second decade in macular specimens but were delayed in nonmacular specimens. All specimens from 20-year-old donors had altered macular Bruch's membranes. T...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(85)90625-7
更新日期:1985-11-15 00:00:00
abstract:PURPOSE:Congenital macular lesions attributed to toxoplasmosis may limit potential visual acuity. The appearance and location of these scars may cause physicians to overlook associated amblyopia. This study reviews the visual outcomes and benefits of amblyopia therapy in children with foveal toxoplasmosis scars. DESIG...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2020.01.034
更新日期:2020-06-01 00:00:00
abstract:PURPOSE:To examine surgical and refractive outcomes of phacoemulsification with intraocular lens (IOL) implant in eyes with prior trabeculectomy. DESIGN:Retrospective observational case-control study. METHODS:The study compared eyes that underwent phacoemulsification with IOL implant at least 3 months post-trabeculec...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2012.11.023
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:To describe the motivations, expectations, and other factors men with X-linked retinoschisis (XLRS) consider when making decisions to participate in an early phase ocular gene therapy clinical trial. DESIGN:Qualitative interview study. METHODS:Men with XLRS who were considering participation in a phase I/IIa ...
journal_title:American journal of ophthalmology
pub_type: 临床试验,杂志文章
doi:10.1016/j.ajo.2019.03.009
更新日期:2019-08-01 00:00:00
abstract:PURPOSE:To study the clinical characteristics of microrips of the retinal pigment epithelium (RPE) in polypoidal choroidal vasculopathy (PCV). DESIGN:Retrospective case series. METHODS:For this study, we retrospectively reviewed 156 consecutive eyes of 136 patients with PCV. The lesions were examined with fluorescein...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2006.12.024
更新日期:2007-05-01 00:00:00
abstract::Four patients, two men 25 and 43 years old and two women 20 and 40 years old, had complete monocular temporal hemianopsias, suggesting that it may be a more common functional deficit than has been recognized. The initial symptoms were visual loss and headache, and eye pain also occurred. Correct diagnosis is possible ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/0002-9394(86)90600-8
更新日期:1986-02-15 00:00:00
abstract:PURPOSE:To evaluate the effect of vitrectomy timing on outcomes for patients with crystalline retained lens fragments receiving vitrectomy 3+ days after cataract surgery. DESIGN:Systematic review and meta-analysis of retrospective interventional cases series. METHODS:Searches of MEDLINE (English, 1/1/85 through 7/30/...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.ajo.2011.02.010
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:To report a Serratia marcescens infection that clinically simulated a conjunctival neoplasm. METHOD:Case report. RESULTS:A healthy 80-year-old man without contact lenses presented with a pink-yellow conjunctival mass that resembled a solid neoplasm. Stains and cultures of material that exuded from the mass du...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(99)00422-5
更新日期:2000-02-01 00:00:00
abstract::We studied a new method for photographing cataractous lens opacaities by retroillumination. The slit-lamp microscope was modified with an adaptor to eliminate the specular reflection from the corneal surface. We construcated two kinds of adaptors for the Zeiss and Goldmann-type slit-lamp microscopes. The cataractous l...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)74852-4
更新日期:1980-08-01 00:00:00
abstract::Study of a father and son who had helicoid peripapillary chorioretinal degeneration suggests that a progressive tearing and retraction of the retinal pigment epithelium or of Bruch's membrane around the optic disk may be involved in the disorder's pathogenesis. We presume that this tearing results primarily from dyspl...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)74552-0
更新日期:1990-03-15 00:00:00
abstract::Eikenella corrodens is a gram-negative, facultative anaerobic bacillus with specific culture and growth requirements and unusual antibacterial susceptibilities. It has only recently been recognized as a human pathogen. Ocular and adnexal infections with this organism are rare especially in children. We treated two chi...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)74487-3
更新日期:1992-11-15 00:00:00
abstract:PURPOSE:To report a case of small cell carcinoma of the thymus metastatic to the orbit. METHODS:At age 37 years, a man who had been previously diagnosed and treated for small cell carcinoma of the thymus was initially examined for vertical diplopia and left proptosis. Computed tomographic scan disclosed a soft tissue ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70836-0
更新日期:1997-09-01 00:00:00
abstract::In an 8-year-old girl with asymptomatic proptosis, computed tomographic scans showed a large medial orbital mass that contoured the globe anteriorly, bowed the optic nerve laterally, and extended posteriorly to the orbital apex. T1-weighted coronal magnetic resonance images showed the mass to be a diffusely enlarged m...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)77878-x
更新日期:1990-11-15 00:00:00
abstract::We implanted nine intraocular lenses for the aphakic correction of congenital monocular cataracts in eight children (eight eyes). During follow-up periods ranging from 18 to 50 months in six children, there were no major complications connected to the surgery. Parental cooperation with treatment for amblyopia was sati...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)77820-1
更新日期:1983-09-01 00:00:00
abstract:PURPOSE:To report a rare complication, delayed suprachoroidal hemorrhage, of needle revision of a nonfunctioning trabeculectomy bleb in a patient with previously undetected hairy cell leukemia. DESIGN:Interventional case report. METHODS; An 89-year-old man presented with massive delayed suprachoroidal hemorrhage after...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(03)00574-9
更新日期:2003-12-01 00:00:00
abstract:PURPOSE:To assess the risks of vitrectomy for the removal of primary and secondary vitreous opacities. DESIGN:Retrospective, nonrandomized, interventional case series. METHODS:We reviewed the results of 116 consecutive cases of vitrectomy for vitreous floaters. Eighty-six cases were primary and 30 cases were secondar...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2011.01.005
更新日期:2011-06-01 00:00:00
abstract:PURPOSE:To report the cases of four patients with hepatitis C virus infection who experienced clinical features that are virtually identical to Vogt-Koyanagi-Harada disease (VKH). DESIGN:Retrospective observational case series. METHODS:Medical records of patients who were referred between January and December 2003 we...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2005.06.020
更新日期:2005-11-01 00:00:00
abstract:PURPOSE:To report the outcome of a new keratoplasty technique aimed at treating full-thickness opacities with minimal removal of recipient endothelium. DESIGN:Interventional case report. METHODS:A deep central scar was removed using microkeratome-assisted mushroom-shaped keratoplasty, consisting of a large anterior s...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2004.12.024
更新日期:2005-07-01 00:00:00
abstract::The location of repository corticosteroid after subtenon injection was determined in 24 patients with macular edema associated with uveitis or anterior segment surgery. Standardized A-scan and B-scan echography were performed immediately before and after each injection. Localization was compared after subtenon injecti...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:
更新日期:1987-03-15 00:00:00
abstract:UNLABELLED:To examine prospectively the efficacy and safety of photorefractive keratectomy and photoastigmatic refractive keratectomy. METHODS:We treated 645 eyes (440 patients) with a VisX Twenty/Twenty excimer laser and followed them up for 12 months. RESULTS:The percentage of eyes with myopia between -5.01 and -10...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/s0002-9394(14)70433-7
更新日期:1996-04-01 00:00:00
abstract:PURPOSE:To evaluate the outcome of intravitreal injection of aflibercept in cases with exudative age-related macular degeneration, (AMD) resistant to injections of bevacizumab or ranibizumab. DESIGN:Retrospective observational case series. METHODS:A retrospective chart review at a single institution was conducted to ...
journal_title:American journal of ophthalmology
pub_type: 杂志文章
doi:10.1016/j.ajo.2013.02.017
更新日期:2013-07-01 00:00:00
abstract:PURPOSE:To report outcomes of Vogt-Koyanagi-Harada (VKH) disease from a clinical trial of antimetabolite therapies. DESIGN:Subanalysis from an observer-masked randomized clinical trial for noninfectious intermediate, posterior, and panuveitis. METHODS:setting: Clinical practice at Aravind Eye Hospitals, India. PATIE...
journal_title:American journal of ophthalmology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ajo.2016.06.004
更新日期:2016-08-01 00:00:00