Infant feeding in relation to islet autoimmunity and type 1 diabetes in genetically susceptible children: the MIDIA Study.

abstract：OBJECTIVE:Advanced glycation end products (AGEs) are thought to have a role in the pathogenesis of diabetes complications. We recently reported the association between skin autofluorescence, as a measure of tissue AGE accumulation, and diabetic neuropathy in a selected diabetic population. In this study, we investigate...

journal_title：Diabetes care

authors： Lutgers HL,Graaff R,Links TP,Ubink-Veltmaat LJ,Bilo HJ,Gans RO,Smit AJ

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:The role of fibrosis in early progressive renal decline in type 2 diabetes is unknown. Circulating WFDC2 (WAP four-disulfide core domain protein 2) and matrix metalloproteinase 7 (MMP-7; Matrilysin) are postulated to be biomarkers of renal fibrosis. This study examined an association of circulating levels of ...

journal_title：Diabetes care

authors： Ihara K,Skupien J,Kobayashi H,Md Dom ZI,Wilson JM,O'Neil K,Badger HS,Bowsman LM,Satake E,Breyer MD,Duffin KL,Krolewski AS

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:To determine maternal parameters with the strongest influence on fetal growth in different periods of pregnancies complicated by an abnormal glucose tolerance test (GTT). RESEARCH DESIGN AND METHODS:Retrospective study of 368 women with gestational diabetes mellitus (GDM; > or = 2 abnormal GTT values, n = 28...

journal_title：Diabetes care

authors： Schaefer-Graf UM,Kjos SL,Kilavuz O,Plagemann A,Brauer M,Dudenhausen JW,Vetter K

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To describe the extent to which hyperglycemia, hypertension, and dyslipidemia are currently detected, treated, and controlled in U.S. veterans with diabetes with and without ischemic heart disease (IHD). RESEARCH DESIGN AND METHODS:A cohort of 3,769 veterans who self-reported diabetes and who received all he...

journal_title：Diabetes care

authors： Smith NL,Chen L,Au DH,McDonell M,Fihn SD

更新日期：2004-05-01 00:00:00

abstract：:Seventeen pregnant diabetic women participated in a special outpatient program during which they learned to self-monitor blood glucose (BG) and to vary insulin dosage on the basis of the results. The Ames Eyetone reflectance meter and the Boehringer Reflomat were used for BG analysis. BG was self-monitored at least tw...

journal_title：Diabetes care

authors： Irsigler K,Bali-Taubald C

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVE:β-Cell autoantibodies are a feature of the preclinical phase of type 1 diabetes. Here, we asked how frequently they revert in a cohort of children at risk for type 1 diabetes and whether reversion has any effect on type 1 diabetes risk. RESEARCH DESIGN AND METHODS:Children were up to 10 years of age and scre...

journal_title：Diabetes care

authors： Vehik K,Lynch KF,Schatz DA,Akolkar B,Hagopian W,Rewers M,She JX,Simell O,Toppari J,Ziegler AG,Lernmark Å,Bonifacio E,Krischer JP,TEDDY Study Group.

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:Impaired awareness of hypoglycemia (IAH) and recurrent severe hypoglycemia (RSH) remain problematic for people with type 1 diabetes (T1D), despite major therapeutic advances. We explored beliefs around hypo- and hyperglycemia in adults with T1D with, and without, IAH and RSH. RESEARCH DESIGN AND METHODS:A cr...

journal_title：Diabetes care

authors： Cook AJ,DuBose SN,Foster N,Smith EL,Wu M,Margiotta G,Rickels MR,Speight J,de Zoysa N,Amiel SA

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:Ipragliflozin, a sodium-glucose cotransporter 2 inhibitor, stimulates glycosuria and lowers glycemia in patients with type 2 diabetes (T2DM). The objective of this study was to assess the pharmacodynamics of ipragliflozin in T2DM patients with impaired renal function. RESEARCH DESIGN AND METHODS:Glycosuria w...

journal_title：Diabetes care

authors： Ferrannini E,Veltkamp SA,Smulders RA,Kadokura T

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:To clarify the contribution of the Asp905Tyr polymorphism of the muscle-specific glycogen-targeting subunit of protein phosphatase 1 (PP1G) to insulin resistance and related diseases. RESEARCH DESIGN AND METHODS:We investigated the Asp905Tyr polymorphism of the PPP1R3 gene, which encodes the muscle-specific ...

journal_title：Diabetes care

authors： Shen GQ,Ikegami H,Kawaguchi Y,Fujisawa T,Hamada Y,Ueda H,Shintani M,Nojima K,Kawabata Y,Yamada K,Babaya N,Ogihara T

更新日期：1998-07-01 00:00:00

abstract：:In order to assess the actual and theoretical limitations of using the traditional urinary glucose determinations as an indicator of plasma glucose concentration, we have measured plasma and urine glucose concentrations in 37 children with diabetes mellitus. A constant blood withdrawal system enabled an accurate estim...

journal_title：Diabetes care

authors： Winter RJ,Traisman HS,Green OC

更新日期：1979-07-01 00:00:00

abstract：OBJECTIVE:To study how type 2 diabetes adversely affects brain volumes, changes in volume, and cognitive function. RESEARCH DESIGN AND METHODS:Regional brain volumes and ischemic lesion volumes in 1,366 women, aged 72-89 years, were measured with structural brain magnetic resonance imaging (MRI). Repeat scans were col...

journal_title：Diabetes care

authors： Espeland MA,Bryan RN,Goveas JS,Robinson JG,Siddiqui MS,Liu S,Hogan PE,Casanova R,Coker LH,Yaffe K,Masaki K,Rossom R,Resnick SM,WHIMS-MRI Study Group.

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:To longitudinally characterize changes in insulin sensitivity in obese women during and after pregnancy. RESEARCH DESIGN AND METHODS:Six glucose-tolerant obese women underwent a 4-h euglycemic-hyperinsulinemic (500-600 pmol/l) clamping during the second (22.5 +/- 2 weeks [mean +/- SD]) and third trimester (3...

journal_title：Diabetes care

authors： Sivan E,Chen X,Homko CJ,Reece EA,Boden G

更新日期：1997-09-01 00:00:00

abstract：:Metformin is and has been considered as first-line therapy for type 2 diabetes for over a quarter of a century. Like other biguanides, metformin can cause a lactic acidosis that is exceptionally rare but fatal. The likelihood of metformin-associated lactic acidosis is substantially higher in patients with kidney impai...

journal_title：Diabetes care

authors： Bakris GL,Molitch ME

更新日期：2016-07-01 00:00:00

abstract：:Diabetic retinopathy is the leading cause of visual impairment and preventable blindness, and represents a significant socioeconomic cost for health care systems worldwide. Therefore, new approaches beyond current standards of diabetes care are needed. Based on the crucial pathogenic role of vascular endothelial growt...

journal_title：Diabetes care

authors： Simó R,Sundstrom JM,Antonetti DA

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:Severe hyperglycemia and hypoglycemia ("severe dysglycemia") are serious complications of type 1 diabetes (T1D). Depression has been associated with severe dysglycemia in type 2 diabetes but has not been thoroughly examined specifically in T1D. We evaluated bidirectional associations between depression and se...

journal_title：Diabetes care

authors： Gilsanz P,Karter AJ,Beeri MS,Quesenberry CP Jr,Whitmer RA

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:Hyperinsulinemia is often associated with several metabolic abnormalities and increased blood pressure, which are risk factors for cardiovascular disease. It has been hypothesized that insulin resistance may underlie all these features. However, recent data suggest that some links between insulin resistance a...

journal_title：Diabetes care

authors： Zanolin ME,Tosi F,Zoppini G,Castello R,Spiazzi G,Dorizzi R,Muggeo M,Moghetti P

更新日期：2006-02-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy and safety of once-weekly semaglutide 1.0 mg s.c. with exenatide extended release (ER) 2.0 mg s.c. in subjects with type 2 diabetes. RESEARCH DESIGN AND METHODS:In this phase 3a, open-label, parallel-group, randomized controlled trial, 813 subjects with type 2 diabetes taking oral ant...

journal_title：Diabetes care

authors： Ahmann AJ,Capehorn M,Charpentier G,Dotta F,Henkel E,Lingvay I,Holst AG,Annett MP,Aroda VR

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:Our objective was to compare the performance of oral glucose tolerance tests (OGTTs) and multivariate models incorporating commonly available clinical variables in their ability to predict future cardiovascular disease (CVD). RESEARCH DESIGN AND METHODS:We randomly selected 2,662 Mexican-Americans and 1,595 ...

journal_title：Diabetes care

authors： Stern MP,Fatehi P,Williams K,Haffner SM

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:We investigated the efficacy and safety of the sodium glucose cotransporter 2 inhibitor, empagliflozin, added to multiple daily injections of insulin (MDI insulin) in obese patients with type 2 diabetes mellitus (T2DM). RESEARCH DESIGN AND METHODS:Patients inadequately controlled on MDI insulin ± metformin (...

journal_title：Diabetes care

authors： Rosenstock J,Jelaska A,Frappin G,Salsali A,Kim G,Woerle HJ,Broedl UC,EMPA-REG MDI Trial Investigators.

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:To investigate the association of carotid atherosclerosis and serum lipoprotein(a) [Lp(a)] concentrations in subjects with NIDDM. RESEARCH DESIGN AND METHODS:We measured carotid intima-media thickness (IMT) and Lp(a) concentrations in 117 NIDDM subjects. Subjects were divided into tertiles according to IMT v...

journal_title：Diabetes care

authors： Yamamoto M,Egusa G,Yamakido M

更新日期：1997-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the presence and correlates of clinically relevant cognitive impairment in middle-aged adults with childhood-onset type 1 diabetes (T1D). RESEARCH DESIGN AND METHODS:During 2010-2013, 97 adults diagnosed with T1D and aged <18 years (age and duration 49 ± 7 and 41 ± 6 ...

journal_title：Diabetes care

authors： Nunley KA,Rosano C,Ryan CM,Jennings JR,Aizenstein HJ,Zgibor JC,Costacou T,Boudreau RM,Miller R,Orchard TJ,Saxton JA

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:To examine the impact of Hurricane Katrina on the health of individuals with diabetes. RESEARCH DESIGN AND METHODS:This was an observational study in 1,795 adults with an A1C measurement 6 months before and 6-16 months after Hurricane Katrina in three health care systems: private (Tulane University Hospital ...

journal_title：Diabetes care

authors： Fonseca VA,Smith H,Kuhadiya N,Leger SM,Yau CL,Reynolds K,Shi L,McDuffie RH,Thethi T,John-Kalarickal J

更新日期：2009-09-01 00:00:00

abstract：:Two-thirds of all deaths in developed countries are caused by the major noncommunicable diseases, e.g., cardiovascular disease, cancer, and non-insulin-dependent diabetes mellitus (NIDDM). There is increasing evidence that these diseases are a consequence of life-style change, and they have a number of risk factors in...

journal_title：Diabetes care

authors： Zimmet PZ

更新日期：1988-03-01 00:00:00

abstract：:The objective of this study was to define the workforce needs for the specialty of Endocrinology, Diabetes, and Metabolism in the United States between 1999 and 2020. An interactive model of factors likely to influence the balance between the supply and demand of endocrinologists during the next 20 years was construct...

journal_title：Diabetes care

authors： Rizza RA,Vigersky RA,Rodbard HW,Ladenson PW,Young WF Jr,Surks MI,Kahn R,Hogan PF

更新日期：2003-05-01 00:00:00

abstract：:Medications may contain significant amounts of various sugars. Data provided by 67 manufacturers have been tabulated to provide specific qualitative and quantitative information on sugar content of selected drug products. Since diabetic individuals may tolerate various sugar forms differently, it is useful to know spe...

journal_title：Diabetes care

authors： Souney PF,Cyr DA,Chang JT,Kaul AF

更新日期：1983-05-01 00:00:00

abstract：:The American Diabetes Association (ADA) "Standards of Medical Care in Diabetes" includes ADA's current clinical practice recommendations and is intended to provide the components of diabetes care, general treatment goals and guidelines, and tools to evaluate quality of care. Members of the ADA Professional Practice Co...

journal_title：Diabetes care

authors： American Diabetes Association.

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Little evidence exists regarding long-term diet quality and the risk of type 2 diabetes among Asian populations, who have undergone a nutrition transition and a diabetes epidemic. RESEARCH DESIGN AND METHODS:A total of 117,919 Chinese men and women, 40-74 years old, free of diabetes, cardiovascular disease, ...

journal_title：Diabetes care

authors： Yu D,Zheng W,Cai H,Xiang YB,Li H,Gao YT,Shu XO

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:Thiazolidinediones (TZDs) and metformin are insulin-sensitizing antihyperglycemic agents with reported benefits on atherosclerosis. Despite extensive use in patients with diabetes and cardiovascular disease, there is a paucity of outcomes data with metformin and none yet with TZDs. We sought to determine the ...

journal_title：Diabetes care

authors： Inzucchi SE,Masoudi FA,Wang Y,Kosiborod M,Foody JM,Setaro JF,Havranek EP,Krumholz HM

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:Adopt a multidisciplinary approach to evaluate a virtually supervised home-based high-intensity interval training (Home-HIT) intervention in people with type 1 diabetes. RESEARCH DESIGN AND METHODS:Eleven individuals with type 1 diabetes (seven women; age 30 ± 3 years; [Formula: see text] 2.5 ± 0.2 L/min; du...

journal_title：Diabetes care

authors： Scott SN,Shepherd SO,Andrews RC,Narendran P,Purewal TS,Kinnafick F,Cuthbertson DJ,Atkinson-Goulding S,Noon T,Wagenmakers AJM,Cocks M

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:To examine the effect of pioglitazone on myocardial insulin sensitivity and left ventricular (LV) function in patients with type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS:Twelve subjects with T2D and 12 with normal glucose tolerance received a euglycemic insulin clamp. Myocardial glucose uptake (MGU) and...

journal_title：Diabetes care

authors： Clarke GD,Solis-Herrera C,Molina-Wilkins M,Martinez S,Merovci A,Cersosimo E,Chilton RJ,Iozzo P,Gastaldelli A,Abdul-Ghani M,DeFronzo RA

更新日期：2017-11-01 00:00:00