Sugar content of selected pharmaceuticals.

abstract：OBJECTIVE:Comparative effectiveness research methods are used to compare the effect of four distinct glucose-control strategies on subsequent myocardial infarction and nephropathy in type 2 diabetes. RESEARCH DESIGN AND METHODS:A total of 58,000 adults with type 2 diabetes and A1C <7% (53 mmol/mol) while taking two or...

journal_title：Diabetes care

authors： Neugebauer R,Fireman B,Roy JA,O'Connor PJ

更新日期：2013-11-01 00:00:00

abstract：:NIDDM in Pima Indians is characterized by obesity, abnormal insulin secretion, insulin resistance, and excess hepatic glucose output. Cross-sectional studies, and, as yet incomplete longitudinal studies of nondiabetic and diabetic Pima Indians suggest that the natural history of the disease begins with insulin resista...

journal_title：Diabetes care

authors： Bogardus C

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVE:We assessed whether type 2 diabetes is associated with renal cell carcinoma (RCC), independent of key potential confounders, in two large prospective cohorts with biennially updated covariate data. RESEARCH DESIGN AND METHODS:A total of 117,570 women from the Nurses' Health Study (NHS) and 48,866 men from th...

journal_title：Diabetes care

authors： Graff RE,Sanchez A,Tobias DK,Rodríguez D,Barrisford GW,Blute ML,Li Y,Sun Q,Preston MA,Wilson KM,Cho E

更新日期：2018-07-01 00:00:00

abstract：:Metformin is and has been considered as first-line therapy for type 2 diabetes for over a quarter of a century. Like other biguanides, metformin can cause a lactic acidosis that is exceptionally rare but fatal. The likelihood of metformin-associated lactic acidosis is substantially higher in patients with kidney impai...

journal_title：Diabetes care

authors： Bakris GL,Molitch ME

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:No prospective, community-based cohort studies have investigated the association between blood pressure and diabetes in Asian ethnicity. We investigated this issue in a 10-year prospective, community-based study of Koreans. RESEARCH DESIGN AND METHODS:We studied whether high blood pressure was associated wit...

journal_title：Diabetes care

authors： Cho NH,Kim KM,Choi SH,Park KS,Jang HC,Kim SS,Sattar N,Lim S

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:The study aim was to determine if multisystemic therapy (MST), an intensive home-based psychotherapy, could reduce hospital admissions for diabetic ketoacidosis (DKA) in youth with poorly controlled type 1 diabetes over 24 months. Potential cost savings from reductions in admissions were also evaluated. RESE...

journal_title：Diabetes care

authors： Ellis D,Naar-King S,Templin T,Frey M,Cunningham P,Sheidow A,Cakan N,Idalski A

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:Some evidence suggests an inverse association between type 2 diabetes and androgens in men and a positive association between type 2 diabetes and androgens in women. The purpose of this community-based study was to evaluate sex differences in the association between endogenous total and bioavailable estrogen ...

journal_title：Diabetes care

authors： Goodman-Gruen D,Barrett-Connor E

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:An artificial pancreas (AP) that automatically regulates blood glucose would greatly improve the lives of individuals with diabetes. Such a device would prevent hypo- and hyperglycemia along with associated long- and short-term complications as well as ease some of the day-to-day burden of frequent blood gluc...

journal_title：Diabetes care

authors： Dassau E,Zisser H,Harvey RA,Percival MW,Grosman B,Bevier W,Atlas E,Miller S,Nimri R,Jovanovic L,Doyle FJ 3rd

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:We aimed to investigate the rate of progression of nonalbuminuric chronic kidney disease (CKD) to end-stage kidney disease (ESKD) or death or major cardiovascular events (MACE) compared with albuminuric and nonalbuminuric phenotypes. RESEARCH DESIGN AND METHODS:We included 10,185 participants with type 2 dia...

journal_title：Diabetes care

authors： Buyadaa O,Magliano DJ,Salim A,Koye DN,Shaw JE

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:We aimed to explore whether frailty was associated with fracture risk and whether frailty could modify the propensity of type 2 diabetes toward increased risk of fractures. RESEARCH DESIGN AND METHODS:Data were from a prospective cohort study. Our primary outcome was time to the first incident clinical fragi...

journal_title：Diabetes care

authors： Li G,Prior JC,Leslie WD,Thabane L,Papaioannou A,Josse RG,Kaiser SM,Kovacs CS,Anastassiades T,Towheed T,Davison KS,Levine M,Goltzman D,Adachi JD,CaMos Research Group.

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:This study tested the hypothesis that genetically raised hyperglycemia increases coronary artery disease (CAD) risk separately from the risk conferred by type 2 diabetes as a whole. RESEARCH DESIGN AND METHODS:We conducted a Mendelian randomization (MR) analysis using summary-level statistics from the larges...

journal_title：Diabetes care

authors： Merino J,Leong A,Posner DC,Porneala B,Masana L,Dupuis J,Florez JC

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:Gestational diabetes mellitus (GDM) may cause obesity in the offspring. The objective was to assess the effect of treatment for mild GDM on the BMI of 4- to 5-year-old children. RESEARCH DESIGN AND METHODS:Participants were 199 mothers who participated in a randomized controlled trial of the treatment of mil...

journal_title：Diabetes care

authors： Gillman MW,Oakey H,Baghurst PA,Volkmer RE,Robinson JS,Crowther CA

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:Plasma copeptin, a surrogate for vasopressin, was associated with albuminuria in population-based studies. These associations are consistent with the effect of vasopressin on albuminuria observed in humans and rodents. The objective of this study was to determine whether plasma copeptin is an independent mark...

journal_title：Diabetes care

authors： Velho G,Bouby N,Hadjadj S,Matallah N,Mohammedi K,Fumeron F,Potier L,Bellili-Munoz N,Taveau C,Alhenc-Gelas F,Bankir L,Marre M,Roussel R

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:Dietary protein is an important modulator of glucose metabolism. However, studies regarding the association between dietary protein intake and gestational diabetes mellitus (GDM) risk are sparse. This study was to examine the association. RESEARCH DESIGN AND METHODS:Our study included 21,457 singleton pregna...

journal_title：Diabetes care

authors： Bao W,Bowers K,Tobias DK,Hu FB,Zhang C

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:To assess the mechanistic effects of the glucagon-like peptide 1 (GLP-1) receptor agonist liraglutide and the dipeptidyl peptidase 4 (DPP-4) inhibitor sitagliptin on (exocrine) pancreatic physiology and morphology. RESEARCH DESIGN AND METHODS:For this randomized, double-blind, parallel-group trial, 55 patien...

journal_title：Diabetes care

authors： Smits MM,Tonneijck L,Muskiet MH,Kramer MH,Pieters-van den Bos IC,Vendrik KE,Hoekstra T,Bruno MJ,Diamant M,van Raalte DH,Cahen DL

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:To study the metabolic effect and the variability of the effect elicited by inhalation of 87.2 U insulin powder combined with an absorption enhancer. The metabolic effect was compared with that of 10.2 U regular insulin injected subcutaneously and of 5.5 U regular insulin given intravenously RESEARCH DESIGN ...

journal_title：Diabetes care

authors： Heinemann L,Klappoth W,Rave K,Hompesch B,Linkeschowa R,Heise T

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:Acarbose inhibits alpha-glucosidases of the small intestine and thus delays glucose release from complex carbohydrates. Therefore, its efficacy and acceptability as a first-line drug in non-insulin-dependent diabetes mellitus (NIDDM) insufficiently treated with diet alone was tested in a randomized double-bli...

journal_title：Diabetes care

authors： Hanefeld M,Fischer S,Schulze J,Spengler M,Wargenau M,Schollberg K,Fücker K

更新日期：1991-08-01 00:00:00

abstract：OBJECTIVE:Foot ulceration is a serious complication of diabetes, and new techniques that can predict wound healing may prove very helpful. We tested the ability of medical hyperspectral technology (HT), a novel diagnostic scanning technique that can quantify tissue oxy- and deoxyhemoglobin to predict diabetic foot ulce...

journal_title：Diabetes care

authors： Khaodhiar L,Dinh T,Schomacker KT,Panasyuk SV,Freeman JE,Lew R,Vo T,Panasyuk AA,Lima C,Giurini JM,Lyons TE,Veves A

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVE:To examine the comparative effectiveness of the sodium-glucose cotransporter 2 inhibitor (SGLT2i) empagliflozin and other non-SGLT2i antihyperglycemics on the risk of major adverse kidney events (MAKE) of estimated glomerular filtration rate (eGFR) decline >50%, end-stage kidney disease, or all-cause mortalit...

journal_title：Diabetes care

authors： Xie Y,Bowe B,Gibson AK,McGill JB,Yan Y,Maddukuri G,Al-Aly Z

更新日期：2020-11-01 00:00:00

abstract：OBJECTIVE:Blood pressure control can reduce the risk of coronary heart disease (CHD) among diabetic patients; however, it is not known whether the lowest risk of CHD is among diabetic patients with the lowest blood pressure level. RESEARCH DESIGN AND METHODS:We performed a prospective cohort study (2000-2009) on diabe...

journal_title：Diabetes care

authors： Zhao W,Katzmarzyk PT,Horswell R,Wang Y,Li W,Johnson J,Heymsfield SB,Cefalu WT,Ryan DH,Hu G

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:To determine the association between serum 25-hydroxyvitamin D (25OHD) and diabetes risk and whether it varies by ethnicity. RESEARCH DESIGN AND METHODS:We performed an analysis of data from participants who attended the morning examination of the Third National Health and Nutrition Examination Survey (1988-...

journal_title：Diabetes care

authors： Scragg R,Sowers M,Bell C,Third National Health and Nutrition Examination Survey.

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:To determine the safety and efficacy of the long-acting insulin analog, insulin glargine, as a component of basal bolus therapy in patients with type 1 diabetes. RESEARCH DESIGN AND METHODS:Patients with type 1 diabetes receiving basal-bolus insulin treatment with NPH human insulin and insulin lispro were ra...

journal_title：Diabetes care

authors： Raskin P,Klaff L,Bergenstal R,Hallé JP,Donley D,Mecca T

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVE:Defects in insulin secretion and insulin action are the major abnormalities in the development of type 2 diabetes. In middle-aged subjects, elevated plasma proinsulin has been found to predict type 2 diabetes. Therefore, our aim was to study the longitudinal relationships between baseline determinations of in...

journal_title：Diabetes care

authors： Zethelius B,Hales CN,Lithell HO,Berne C

更新日期：2004-06-01 00:00:00

abstract：OBJECTIVE:Assessing updated incidence of type 1 diabetes in 0- to 14-year-old children in Liguria, a Northwest region of Italy. RESEARCH DESIGN AND METHODS:Incident cases were recorded prospectively from 1989 to 1998. Incidence rates (IRs) were standardized to the 1999 world population using the direct method. The ind...

journal_title：Diabetes care

authors： Cotellessa M,Barbieri P,Mazzella M,Bonassi S,Minicucci L,Lorini R

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVE:To investigate the role of hyperglycemia in mediating the clinical association of NIDDM with hypertension and left ventricular dysfunction and hypertrophy. RESEARCH DESIGN AND METHODS:Since hyperglycemia elevates cytosolic free calcium (Cai) both in myocardial and vascular smooth muscle cells, we utilized nu...

journal_title：Diabetes care

authors： Barbagallo M,Gupta RK,Resnick LM

更新日期：1996-12-01 00:00:00

abstract：OBJECTIVE:Little evidence exists regarding long-term diet quality and the risk of type 2 diabetes among Asian populations, who have undergone a nutrition transition and a diabetes epidemic. RESEARCH DESIGN AND METHODS:A total of 117,919 Chinese men and women, 40-74 years old, free of diabetes, cardiovascular disease, ...

journal_title：Diabetes care

authors： Yu D,Zheng W,Cai H,Xiang YB,Li H,Gao YT,Shu XO

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVE:We prospectively investigated in hypertensive patients with type 2 diabetes if bedtime treatment with ≥1 hypertension medications exerts better blood pressure control and cardiovascular risk reduction than conventional therapy, in which all medications are ingested in the morning. RESEARCH DESIGN AND METHODS...

journal_title：Diabetes care

authors： Hermida RC,Ayala DE,Mojón A,Fernández JR

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:Sulfonylureas block the activation of vascular potassium-dependent ATP channels and impair the vasodilating response to ischcmia in nondiabetic individuals, but it is not know whether this occurs in type 2 diabetic patients under chronic treatment with these drugs. Glimepiride, a new sulfonylurea, apparently ...

journal_title：Diabetes care

authors： Spallarossa P,Schiavo M,Rossettin P,Cordone S,Olivotti L,Cordera R,Brunelli C

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:Type 2 diabetes is frequently complicated with atherogenic dyslipidemia. This study aimed to evaluate the efficacy and safety of pemafibrate (K-877) in patients with type 2 diabetes comorbid with hypertriglyceridemia. RESEARCH DESIGN AND METHODS:Patients were randomly assigned to three groups and received pl...

journal_title：Diabetes care

authors： Araki E,Yamashita S,Arai H,Yokote K,Satoh J,Inoguchi T,Nakamura J,Maegawa H,Yoshioka N,Tanizawa Y,Watada H,Suganami H,Ishibashi S

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVE:To assess the effects of empagliflozin, a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor, on broad biological systems through proteomics. RESEARCH DESIGN AND METHODS:Aptamer-based proteomics was used to quantify 3,713 proteins in 144 paired plasma samples obtained from 72 participants across the ...

journal_title：Diabetes care

authors： Ferrannini E,Murthy AC,Lee YH,Muscelli E,Weiss S,Ostroff RM,Sattar N,Williams SA,Ganz P

更新日期：2020-09-01 00:00:00