Abstract:
:Seven cases of subacute central and peripheral neurologic dysfunction developed in 18 workers employed in the manufacture of reinforced plastic bathtubs. Cases were characterized by weight loss, dizziness, paresthesias, muscle weakness, incontinence, memory loss, and loss of peripheral, color, and night vision. Neuropathies began distally, involved both sensory and motor function, and were associated with prolonged sensory latency, muscle fibrillation, and reduced numbers of functioning motor units. One patient developed posterior lenticular cataracts. Slow improvement occurred on removal from exposure, but residual neuropathies persisted for as long as two years. Epidemiologic investigation disclosed that the first case developed approximately two weeks after introduction of a new plastic foaming agent, 2-t-butylazo-2-hydroxy-5-methylhexane (BHMH). All cases occurred in workers exposed directly to BHMH. No new cases developed after use of BHMH was discontinued. A survey of the firm which produced BHMH and of 68 user firms found two additional clusters of mild neuropathy which may have been caused by BHMH. BHMH was withdrawn from distribution following discovery of these cases. Subsequently, BHMH has been shown in rats to be a potent neurotoxin. Adequate premarket testing could have averted this outbreak.
journal_name
Am J Public Healthjournal_title
American journal of public healthauthors
Horan JM,Kurt TL,Landrigan PJ,Melius JM,Singal Mdoi
10.2105/ajph.75.5.513subject
Has Abstractpub_date
1985-05-01 00:00:00pages
513-7issue
5eissn
0090-0036issn
1541-0048journal_volume
75pub_type
杂志文章abstract:OBJECTIVES:We examined the association between neighborhood convenience stores and diet outcomes for 20 years of the Coronary Artery Risk Development in Young Adults study. METHODS:We used dietary data from the Coronary Artery Risk Development in Young Adults study years 1985-1986, 1992-1993, and 2005-2006 (n = 3299; ...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2014.302435
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVES:We explored an innovative strategy for targeted testing and disease management among immigrant communities at risk for tuberculosis. METHODS:Taxi drivers were recruited at an airport holding lot to undergo tuberculin skin testing (Mantoux). After receiving their test results in a location convenient for the...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2003.019620
更新日期:2005-01-01 00:00:00
abstract:OBJECTIVES: To determine if the Teen Outreach Program (TOP), a youth development and service learning program, can reduce sexual risk-taking behaviors compared with a business as usual or benign counterfactual. METHODS: We synthesized results of 5 independent studies conducted in 5 geographically and ethnically divers...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2016.303307
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVES:Overall and cause-specific mortality among persons with diabetes in North Dakota was estimated and compared with estimates from previous population-based studies. METHODS:Data were derived from North Dakota death certificate data, which included unique information on decedents' diabetes status and Behaviora...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.91.1.84
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVES:We assessed the impact of changes in dimensions of the psychosocial work environment on risk of depression in a longitudinal cohort of Canadian workers who were free of depression when work conditions were initially reported. METHODS:Using a sample (n = 3735) from the Canadian National Population Health Sur...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2011.300376
更新日期:2012-02-01 00:00:00
abstract::Affirmative action programs of all types are under attack legally and politically. Although medical schools have not been specifically targeted, their affirmative action programs, like others in higher education, are potentially in danger. This article examines the current legal status of affirmative action in medical...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.89.8.1256
更新日期:1999-08-01 00:00:00
abstract::We have summarized the evolution of the Nurses' Health Study (NHS), a prospective cohort study of 121 700 married registered nurses launched in 1976; NHS II, which began in 1989 and enrolled 116 430 nurses; and NHS3, which began in 2010 and has ongoing enrollment. Over 40 years, these studies have generated long-term,...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2016.303338
更新日期:2016-09-01 00:00:00
abstract::The Centers for Disease Control (CDC) has proposed revising the AIDS surveillance definition to include any HIV-seropositive person with a CD4 cell count of less than 200 cells per microliter. Based on a study of persons receiving treatment for HIV infection, this new definition would lead to an estimated 50% increase...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.82.11.1531
更新日期:1992-11-01 00:00:00
abstract::Public health, like politics, is the art of the possible. To maximize effectiveness, public health officers in any jurisdiction should (1) get good data and ensure timely and effective dissemination; (2) prioritize and tackle more difficult initiatives first; (3) find, fight, and win winnable battles in areas where pr...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2016.303204
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVES:This analysis was conducted to determine whether atopic disorders were related to social class in a pediatric population of a former socialist country. METHODS:A cross-sectional study of 2471 schoolchildren was carried out in 1992 and 1993 in 3 towns in the former East Germany. Parents completed a standardi...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.88.9.1319
更新日期:1998-09-01 00:00:00
abstract::Sexual and reproductive health remains the contentious concept it was at the 1994 United Nations International Conference on Population and Development (ICPD), held in Cairo, Egypt. In light of the recent 15-year review of ICPD, we suggest several areas where advocates, practitioners, and researchers can inform future...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2009.177873
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVES:We examined the effects of changes in Rhode Island's Lead Hazard Mitigation Law in 2005 on children's blood lead levels. METHODS:We used 2005 to 2009 data from Rhode Island's Lead Elimination Surveillance System; city tax assessor records in Central Falls, Pawtucket, Providence, and Woonsocket, Rhode Island...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2014.301908
更新日期:2014-08-01 00:00:00
abstract:OBJECTIVES:To describe salient epidemiological characteristics of Zika virus outbreaks across the world and to examine the clinical presentations, complications, and atypical manifestations related to their occurrence in recent history. METHODS:We conducted a systematic review of the literature by searching through ME...
journal_title:American journal of public health
pub_type: 历史文章,杂志文章,评审
doi:10.2105/AJPH.2016.303112
更新日期:2016-04-01 00:00:00
abstract::Members of the Reorganized Church of Jesus Christ of Latter-Day Saints (RLDS) are dissuaded from the use of tobacco, alcohol, and hot drinks. A well-balanced diet is also stressed. This study compares the 1972-78 mortality experience of the Missouri RLDS with three other population groups. The findings show Missouri R...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.71.12.1350
更新日期:1981-12-01 00:00:00
abstract::During the 1980-81 academic year, 249 academic institutions were surveyed concerning professional preparation in patient education. Various degrees of involvement were reported by 39 institutions. Findings indicate that such programs are relatively new, and enrollment in degree programs and courses is limited. Placeme...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.72.2.180
更新日期:1982-02-01 00:00:00
abstract::A random sample of employees was surveyed 20 months after a non-smoking policy was implemented at the New England Telephone Company in 1986. Overall, 21 percent of respondents who were smoking at the time they heard about the policy had quit smoking; 42 percent of quitters said they stopped smoking because of the poli...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.81.2.202
更新日期:1991-02-01 00:00:00
abstract::We describe the behavioral characteristics and sexually transmitted disease (STD) prevalence of Chinese men who have sex with men (MSM) (n = 41) from a national probability sample of men (n = 1861). Most MSM were partnered with females (97%) and had a low rate of consistent condom use (7%). More MSM than heterosexual ...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2008.150037
更新日期:2009-11-01 00:00:00
abstract::Academic occupational health centers can support state-based occupational disease surveillance by playing a role in case identification and management, physician education, workplace investigation, and surveillance case criteria development. The existing centers can also serve as models for developing new clinics. As ...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.79.suppl.58
更新日期:1989-12-01 00:00:00
abstract:OBJECTIVES:This study assessed changes in the prevalence of hearing impairment in persons aged 50 years and older over the past 30 years and identified risk factors. METHODS:Age-adjusted hearing impairment prevalence rates at four time intervals were calculated from the Alameda County Study (n = 5108). Logistic regres...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.87.3.440
更新日期:1997-03-01 00:00:00
abstract:OBJECTIVES:We evaluated emergency department (ED)-based outreach for the State Children's Health Insurance Program (SCHIP). METHODS:We conducted a multicenter trial among uninsured children (< or = 18 years) who presented to 5 EDs in 2001 and 2002. On-site staff enrolled consecutive subjects for a control period follo...
journal_title:American journal of public health
pub_type: 杂志文章,多中心研究
doi:10.2105/AJPH.2003.037242
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVES:Whether or not spermicides can reduce the risk of human immunodeficiency virus (HIV) transmission remains an important question for the control of heterosexual HIV transmission. The authors provide estimates from a reanalysis of one of the few observational studies on the efficacy of condoms and spermicides,...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.88.4.590
更新日期:1998-04-01 00:00:00
abstract:OBJECTIVES:This study investigated whether low concentrations of ambient air pollutants are associated with hospital admissions for ischemic cardiac and cerebrovascular diseases. METHODS:Associations between daily concentrations of sulfur dioxide, nitric oxide, nitrogen dioxide, ozone, and particulates and daily hospi...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.86.9.1273
更新日期:1996-09-01 00:00:00
abstract::This study was designed to evaluate the effectiveness of a large scale program to improve health care for high-risk adolescents. Seven clinics, funded to provide comprehensive primary care to adolescents, were compared to three non-funded clinics. The majority of the 2,788 adolescent patients sampled in these clinics ...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.79.8.999
更新日期:1989-08-01 00:00:00
abstract::Four years have passed since the institution of the cease-fire in Yugoslavia, and questions remain as to how Kosovar women are faring in the country's postwar reconstruction. Reports, albeit fragmented, suggest that violence against women began to increase in 1998 and 1999. This trend continued through 2001, even whil...
journal_title:American journal of public health
pub_type: 杂志文章,评审
doi:10.2105/ajph.94.8.1304
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVES:We examined the effectiveness of community-level HIV prevention programming for men who have sex with men. METHODS:We used multilevel methods to examine unprotected intercourse by bisexual men (n = 1016) with male and female partners in geographic regions with and without HIV prevention programming. RESULT...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.94.7.1181
更新日期:2004-07-01 00:00:00
abstract::Cancer mortality in Texas 1969-80 was 25 per cent lower among Mexican American males compared to other Whites; among females, rates were only 4 per cent lower. Reduced mortality was primarily a result of lower rates for cancers of the most common sites: lung, colon, breast and prostate. However, for cancers of the sto...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.77.7.851
更新日期:1987-07-01 00:00:00
abstract::We administered the Center for Epidemiological Studies Depression (CES-D) Scale to 547 San Francisco Latinos as part of a random digit dialing telephone survey to evaluate smoking behavior. Both men and women current smokers had the highest mean CES-D levels (9.7 and 14.3, respectively). Logistic regression analysis a...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.80.12.1500
更新日期:1990-12-01 00:00:00
abstract::Social work education plays a critical role in preparing social workers to lead efforts that improve health. Because of the dynamic health care landscape, schools of social work must educate students to facilitate health care system improvements, enhance population health, and reduce medical costs. We reviewed the exi...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/AJPH.2017.304054
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVES:How do health care professionals assess the care of hospital patients near the end of life? Are physicians and nurses aware of and in agreement with national recommendations regarding patients' rights to forgo life-sustaining medical treatments and to receive adequate pain control? METHODS:We surveyed 687 p...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.83.1.14
更新日期:1993-01-01 00:00:00
abstract::A nationwide evaluation of 49 Veterans Administration drug dependence treatment programs was conducted using a sample of 1,655 patients. Their status with reference to seven treatment goals was assessed at admission and again 11 months later to determine change. The following changes were observed: a large decrease in...
journal_title:American journal of public health
pub_type: 杂志文章
doi:10.2105/ajph.68.1.39
更新日期:1978-01-01 00:00:00