Gastrointestinal blood flow and O2 uptake in piglets: recovery from hypoxemia.

abstract：:Up to 20% of pregnant women smoke and there is indirect evidence that certain tobacco-specific metabolites can cross the placental barrier and are genotoxic to the fetus. The presence of micronuclei results from chromosome damage and reflects the degree of underlying genetic instability. Fetal blood was obtained from ...

journal_title：Pediatric research

authors： Zalacain M,Sierrasesumaga L,Larrañnaga C,Patiñno-García A

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:This study aimed to determine the prevalence of respiratory pathogens among newborns admitted to a neonatal medium care unit (NMCU) and to identify clinical predictors. METHODS:A 1-y observational study was performed of neonates admitted to an NMCU in Amsterdam, The Netherlands. Nasopharyngeal samples were ...

journal_title：Pediatric research

authors： Smit PM,Pronk SM,Kaandorp JC,Weijer O,Lauw FN,Smits PH,Claas EC,Mulder JW,Beijnen JH,Brandjes DP

更新日期：2013-03-01 00:00:00

abstract：:Plasma selenium concentration and glutathione peroxidase activity in red blood cells were determined in subjects from different age groups. The selenium level (mean +/- SD) found in infancy (0 to 6 months) was 2 +/- 0.6 micrograms/dl, with the lowest value of 1 microgram/dl observed in a 4-month-old infant. These leve...

journal_title：Pediatric research

authors： van Caillie-Bertrand M,Degenhart HJ,Fernandes J

更新日期：1986-06-01 00:00:00

abstract：:Evaluation of nonlinear heart rate (HR) dynamics has received considerable attention in the pediatric literature because such analyses not only provide insight into underlying control mechanisms, but may also help to differentiate between normal and abnormal infants. The purpose of this study was to determine, in eigh...

journal_title：Pediatric research

authors： Mooney DM,Groome LJ,Holland SB,Smith YD

更新日期：1998-07-01 00:00:00

abstract：:We used quin2, a high affinity fluorescent calcium indicator to measure free cytosolic Ca++ in neutrophils isolated from fresh heparinized blood of 13 cystic fibrosis (CF) patients (age range 6-32 yr) and 11 healthy individuals (age range 25-41 yr) as controls. The mean value of free cytosolic Ca++ for CF patients was...

journal_title：Pediatric research

authors： Suter S,Lew PD,Ballaman J,Waldvogel FA

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:Exposure to inflammation exacerbates injury in neonatal encephalopathy (NE). We hypothesized that brain biomarker mRNA, cytokine mRNA and microRNA differentiate inflammation (E. coli LPS), hypoxia (Hypoxia), and inflammation-sensitized hypoxia (LPS+Hypoxia) in an NE piglet model. METHODS:Sixteen piglets wer...

journal_title：Pediatric research

authors： Lingam I,Avdic-Belltheus A,Meehan C,Martinello K,Ragab S,Peebles D,Barkhuizen M,Tann CJ,Tachtsidis I,Wolfs TGAM,Hagberg H,Klein N,Fleiss B,Gressens P,Golay X,Kramer BW,Robertson NJ

更新日期：2020-06-10 00:00:00

abstract：:To clarify the prevalence of Japanese children thought to be at a risk for infection with GB virus-C (GBV-C)/hepatitis G virus (HGV), we investigated the detection rates of serum GBV-C/ HGV ribonucleic acid (RNA) by reverse transcription-seminested PCR and serum anti-HGV-E2 antibody by ELISA in 162 children with histo...

journal_title：Pediatric research

authors： Goto K,Sugiyama K,Li R,Miyake Y,Ando T,Mizutani F,Terabe K,Mizuno K,Wada Y

更新日期：1999-01-01 00:00:00

abstract：:Several hours after an hypoxic-ischemic injury to the developing brain, hyperemia, then seizures, edema, and infarction can develop. The roles of nitric oxide (NO) synthesis and excitotoxin accumulation during these later phases of injury are not known. The time course of extracellular levels of amino acids within the...

journal_title：Pediatric research

authors： Tan WK,Williams CE,During MJ,Mallard CE,Gunning MI,Gunn AJ,Gluckman PD

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Bicuspid aortic valve (BAV) is the most common type of congenital heart disease (CHD) and has a proposed genetic etiology. BAV is categorized by cusp fusion, with right-left (R-L) cusp fusion being associated with additional CHD, and right-noncoronary cusp (R-NC) fusion being associated with aortic valve dys...

journal_title：Pediatric research

authors： Bonachea EM,Chang SW,Zender G,LaHaye S,Fitzgerald-Butt S,McBride KL,Garg V

更新日期：2014-08-01 00:00:00

abstract：:This study was carried out to determine the influence and site of action of N omega-nitro-L-arginine methylester, an L-arginine analogue, on basal pulmonary vascular tone and hypoxic vasoconstriction in neonatal pig lungs. We studied isolated lungs from pigs, age 14.5 +/- 0.5 (SD) d and weight 3.6 +/- 0.7 kg, perfused...

journal_title：Pediatric research

authors： Nelin LD,Dawson CA

更新日期：1993-09-01 00:00:00

abstract：:Cerebral concentrations of phenylalanine (PHE) were measured by means of quantitative in vivo 1H MR spectroscopy in 8 adult patients treated early for phenylketonuria type I. A 1.5-Tesla routine magnetic resonance scanner, localization sequence with short echo time (20 ms), and a fully automated data processing scheme...

journal_title：Pediatric research

authors： Pietz J,Kreis R,Boesch C,Penzien J,Rating D,Herschkowitz N

更新日期：1995-11-01 00:00:00

abstract：:Three members of a Virginia family with a bleeding disorder were found to have a serum defect in thromboplastin generation similar to the previously reported "Car. factor" deficiency. Sera from three members of the original Car. family did not correct the defect of affected members of the Virginia family. Partial thro...

journal_title：Pediatric research

authors： Komp DM

更新日期：1975-04-01 00:00:00

abstract：:Preterm infants are prone to abnormal bacterial colonization of the intestine with ensuing adverse health effects. To examine whether the oral application of Bifidobacterium lactis Bb12 (probiotic) may improve selected indicators of health status in preterm infants, a double blind, placebo controlled randomized clinic...

journal_title：Pediatric research

authors： Mohan R,Koebnick C,Schildt J,Mueller M,Radke M,Blaut M

更新日期：2008-10-01 00:00:00

abstract：:Exposure of neonatal rats to > or = 95% O2 for 2 wk, a widely used model of oxidant/antioxidant interactions in neonatal lung injury, results in arrested lung growth without the dysplastic lesions observed in chronic human neonatal lung injury. To determine whether dysplastic lung cell growth would be seen at lesser O...

journal_title：Pediatric research

authors： Han RN,Buch S,Tseu I,Young J,Christie NA,Frndova H,Lye SJ,Post M,Tanswell AK

更新日期：1996-06-01 00:00:00

abstract：:The in vitro incorporation and transport of plasma nonesterified fatty acids into phospholipids of red cell membranes have been studied in cystic fibrosis and healthy children. Red blood cells were labeled in vitro by an active "acyltransferase"-dependent incorporation of radioactively labeled nonesterified fatty acid...

journal_title：Pediatric research

authors： Rogiers V,Mandelbaum I,Mozes N,Vertongen F,Dab I,Crokaert R,Vis HL

更新日期：1982-09-01 00:00:00

abstract：:Hypoxic-ischemic injuries can evolve over several days, and recent studies suggest that further neuronal death may occur 6 to 72 h later. Because cerebral temperature is an important determinant of outcome during the primary injury, we investigated the effect of temperature, on outcome, during the later phases of inju...

journal_title：Pediatric research

authors： Sirimanne ES,Blumberg RM,Bossano D,Gunning M,Edwards AD,Gluckman PD,Williams CE

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:The aim was to identify susceptibility alleles for infantile hypertrophic pyloric stenosis (IHPS) in a pedigree previously linked to IHPS5 on chromosome 16q24. METHODS:We screened the positional and functional candidate gene FOXF1 by Sanger sequencing in a single affected individual. All family members for ...

journal_title：Pediatric research

authors： Everett KV,Ataliotis P,Chioza BA,Shaw-Smith C,Chung EMK

更新日期：2017-04-01 00:00:00

abstract：:Hemophagocytic lymphohistiocytosis (HLH) and Langerhans cell histiocytosis (LCH) are members of a group of rare heterogenous disorders, the histiocytoses, characterized by uncontrolled accumulation of pleomorphic infiltrates of leukocytes. The etiology of these diseases is mainly unknown. CD45 is a hemopoietic cell sp...

journal_title：Pediatric research

authors： Boxall S,McCormick J,Beverley P,Strobel S,De Filippi P,Dawes R,Klersy C,Clementi R,De Juli E,Ferster A,Wallace D,Aricò M,Danesino C,Tchilian E

更新日期：2004-03-01 00:00:00

abstract：:Naloxone has been shown to reverse the hemodynamic sequelae of experimental septic shock in adult animal models. Its effectiveness in the newborn has not been studied. To further investigate the efficacy of naloxone, we instrumented 18 piglets for continuous measurement of mean arterial pressure, mean pulmonary arteri...

journal_title：Pediatric research

authors： Miller RR,Menke JA,Hansen NB,Zwick DL,Bickers RG,Nowicki PT

更新日期：1986-08-01 00:00:00

abstract：:The mitochondria play a major role in the regulation of intracellular calcium. Despite the fact that the enterocytes receive the majority of absorbed calcium, the role of the intestinal mitochondria in calcium transport during maturation is not known. Therefore, the current studies were designed to characterize calciu...

journal_title：Pediatric research

authors： Kikuchi T,Kikuchi K,Arab N,Ghishan FK

更新日期：1989-01-01 00:00:00

abstract：:Hyperprostaglandin E syndrome (HPS), the prenatal variant of Bartter's syndrome, is characterized by a marked and selective stimulation of prostaglandin E (PGE2) synthesis. In the study group HPS patients showed increased urinary levels of PGE2, an index of renal, and of 11 alpha-hydroxy-9,15-dioxo-2,3,4,5,20-pentanor...

journal_title：Pediatric research

authors： Nüsing RM,Schaub TP,Klein T,Schweer H,Seyberth HW

更新日期：1997-08-01 00:00:00

abstract：:Carbonic anhydrase II (CA II) is the only soluble isozyme of CA which is known to be expressed in kidney. We recently identified a deficiency of this enzyme as the basis for the autosomal recessive syndrome of osteopetrosis with renal tubular acidosis and cerebral calcification. In order to explore the physiological i...

journal_title：Pediatric research

authors： Sly WS,Whyte MP,Krupin T,Sundaram V

更新日期：1985-10-01 00:00:00

abstract：:Astrocyte end-feet ensheathe blood vessels in the brain and are believed to provide structural integrity to the cerebral vasculature. We sought to determine in developing infants whether the coverage of blood vessels by astrocyte end-feet is decreased in germinal matrix (GM) compared with cerebral cortex and white mat...

journal_title：Pediatric research

authors： El-Khoury N,Braun A,Hu F,Pandey M,Nedergaard M,Lagamma EF,Ballabh P

更新日期：2006-05-01 00:00:00

abstract：:The transport of phosphate into jejunal brush border membrane vesicles isolated from 14- to 42-day-old rats was investigated using a rapid filtration technique. The presence of a sodium gradient enhanced phosphate uptake at all ages. Both sodium-dependent phosphate uptake and passive phosphate uptake declined with inc...

journal_title：Pediatric research

authors： Borowitz SM,Ghishan FK

更新日期：1985-12-01 00:00:00

abstract：:Sequential magnitude and the rate of change in tracheal mechanics after application of intermittent positive pressure (IPP), and the time constant, tau, of this deformation were determined in fetal (21 and 27 days gestation), neonatal (term, 31 days gestation) and adult rabbits. In vitro tracheal mechanics were determ...

journal_title：Pediatric research

authors： Bhutani VK,Shaffer TH

更新日期：1982-10-01 00:00:00

abstract：:Although cisapride is widely used to treat gastrointestinal motility disorders, it has been associated with QT prolongation, torsades de pointes, and cardiac arrest. Only in children, however, has atrioventricular (AV) block after cisapride been reported. This study used Langendorff perfusion to determine the direct e...

journal_title：Pediatric research

authors： Wu MH,Su MJ,Sun SS

更新日期：2003-03-01 00:00:00

abstract：:The factors that mediate the postnatal fall in pulmonary vascular resistance, which is crucial for normal gas exchange, are not fully understood. The endothelium has been implicated in this phenomenon, through the release of vasorelaxant factors such as nitric oxide (NO). Human pulmonary expression of endothelial NO s...

journal_title：Pediatric research

authors： Lévy M,Maurey C,Dinh-Xuan AT,Vouhé P,Israël-Biet D

更新日期：2005-05-01 00:00:00

abstract：:Twenty-two reported cases of neuroblastoma missed by the mass screening programs were reviewed (six cases in Sapporo City where a quantitative measurement for both vanillylmandelic acid (VMA) and homovanillic acid (HVA) is used and 16 cases in the districts of qualitative judgment only for VMA), and some potential fac...

journal_title：Pediatric research

authors： Nishi M,Miyake H,Takeda T,Takasugi N,Sato Y,Hanai J,Kawai T

更新日期：1989-12-01 00:00:00

abstract：:Dietary n-3 polyunsaturated fatty acids (PUFA) may represent a mode of allergy prevention. Cord blood (CB) CD34+ hemopoietic progenitors are altered in infants at risk of atopy. We therefore studied the effects of dietary n-3 PUFA supplementation during pregnancy on numbers and function of progenitors in neonates at h...

journal_title：Pediatric research

authors： Denburg JA,Hatfield HM,Cyr MM,Hayes L,Holt PG,Sehmi R,Dunstan JA,Prescott SL

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Appearance of sleep cycling has been associated with good outcome in term and preterm infants, but the normal time of its appearance has not been determined. The objectives of this study were, to correlate the time of sleep cycling appearance and the length of quiet sleep in neonates with different degrees o...

journal_title：Pediatric research

authors： Abramsky R,Stavsky M,Novack V,Shany E

更新日期：2020-03-01 00:00:00