Serum estradiol level during withdrawal bleeding as a predictive factor for intermittent ovarian function in women with primary ovarian insufficiency.

abstract：:We describe a case of diabetes insipidus (DI) due to a pituitary tumor in a 33-year-old pregnant woman who developed a sudden onset of polyuria (over 8 l/day) and polydipsia at 30 weeks of gestation. Her plasma concentration of vasopressin (AVP) was low compared with high serum osmolality (298 mOsm/kg), and her urine ...

journal_title：Endocrine journal

authors： Hashimoto M,Ogura T,Otsuka F,Yamauchi T,Mimura Y,Hayakawa N,Makino H,Ota Z,Seki N,Hiramatsu Y,Kudo N

更新日期：1996-10-01 00:00:00

abstract：:Reactive oxygen species (ROS) are induced under diabetic conditions and are likely associated with the development of type 2 diabetes. It is also known that ROS production is facilitated in the presence of copper ion through the Fenton reaction. The aim of this study was to examine the involvement of copper ion in the...

journal_title：Endocrine journal

authors： Tanaka A,Kaneto H,Miyatsuka T,Yamamoto K,Yoshiuchi K,Yamasaki Y,Shimomura I,Matsuoka TA,Matsuhisa M

更新日期：2009-01-01 00:00:00

abstract：:We studied the cross-sectional relationship between GA and HbA1c in 142 type 2 diabetic patients who had an HbA1c level < 7.5% for at least one year without fluctuation by more than 0.5%. We also followed the changes of GA and HbA1c in 18 type 2 diabetic patients for 16 weeks as they progressed from untreated severe h...

journal_title：Endocrine journal

authors： Takahashi S,Uchino H,Shimizu T,Kanazawa A,Tamura Y,Sakai K,Watada H,Hirose T,Kawamori R,Tanaka Y

更新日期：2007-02-01 00:00:00

abstract：:Pregnancy in acromegalic patients is a rare event, but is usually uneventful, with stable GH and IGF-I levels and no tumor enlargement. Medical treatment can usually be withdrawn without problems and although no major adverse event has been reported, the suspension of drug treatments is generally recommended. No cas...

journal_title：Endocrine journal

authors： Kasuki L,Neto LV,Takiya CM,Gadelha MR

更新日期：2012-01-01 00:00:00

abstract：:Triple A syndrome, also known as Allgrove syndrome, is a rare autosomal recessive disorder characterized by adrenal insufficiency, achalasia and alacrima. It has recently been reported that this syndrome is caused by mutations in the AAAS gene. In the present study, we analyzed the AAAS gene in a Japanese patient with...

journal_title：Endocrine journal

authors： Katsumata N,Hirose H,Kagami M,Tanaka T

更新日期：2002-02-01 00:00:00

abstract：:The purpose of this study was to review the phenotypic and endocrine features or a series of patients with ambiguous genitalia or sex-reversal due to gonadal dysgenesis (GD) and to analyse the impact of these on the decision about sex of rearing. This study is a retrospective analysis of 22 patients with GD treated be...

journal_title：Endocrine journal

authors： Cameron FJ,Montalto J,Byrt EA,Sinclair AH,Warne GL

更新日期：1997-02-01 00:00:00

abstract：:Cushing's disease rarely appears as a consequence of hereditary disease. However, familial diseases with diminished glucocorticoid feedback are associated with secondary hypercorticotropinism and have been shown to give rise to pituitary adenomas. We here describe the rare case of a 30-year old female patient with con...

journal_title：Endocrine journal

authors： Haase M,Schott M,Kaminsky E,Lüdecke DK,Saeger W,Fritzen R,Schinner S,Scherbaum WA,Willenberg HS

更新日期：2011-01-01 00:00:00

abstract：:Several studies have shown the correlation between vitamin D [25(OH)D] deficiency and thyroid autoimmunity and reducing of thyroid autoantibodies in patients with normal levels of vitamin D combining with thyroid hormone replacement. However, other authors not agree with this association. It is still unclear whether t...

journal_title：Endocrine journal

authors： Botelho IMB,Moura Neto A,Silva CA,Tambascia MA,Alegre SM,Zantut-Wittmann DE

更新日期：2018-10-29 00:00:00

abstract：:The serum T3 to T4 ratio is a useful indicator for differentiating destruction-induced thyrotoxicosis from Graves' thyrotoxicosis. However, the usefulness of the serum free T3 (FT3) to free T4 (FT4) ratio is controversial. We therefore systematically evaluated the usefulness of this ratio, based on measurements made u...

journal_title：Endocrine journal

authors： Yoshimura Noh J,Momotani N,Fukada S,Ito K,Miyauchi A,Amino N

更新日期：2005-10-01 00:00:00

abstract：:To determine whether patients with medullary thyroid carcinoma (MTC) develop other endocrine neoplasms or their relatives develop MTC, we investigated the mutations in the RET proto-oncogene in patients with multiple endocrine neoplasia type 2B (MEN 2B, N = 1) and sporadic MTC (N = 6). DNA from MTC tissue and the peri...

journal_title：Endocrine journal

authors： Migita M,Hiromatsu Y,Sato M,Yang D,Kameo J,Jimi A,Nonaka K

更新日期：1997-08-01 00:00:00

abstract：:In an attempt to define the hypothalamic-pituitary-adrenal (HPA) axis in non-insulin dependent diabetic rats (WBN/Kob), we measured plasma corticotropin releasing factor (CRF), as well as arginine vasopressin (AVP), ACTH, and corticosterone (B), CRF concentrations in the median eminence (ME), the remainder of the hypo...

journal_title：Endocrine journal

authors： Tojo C,Takao T,Nishioka T,Numata Y,Suemaru S,Hashimoto K

更新日期：1996-04-01 00:00:00

abstract：:Tumor necrosis factor-alpha (TNF-alpha) in placenta is believed to be involved in pathogenesis of intrauterine growth restriction. In contrast, insulin-like growth factors (IGFs) are believed to be important for stimulation of fetal and placental growth. IGF-I stimulates metabolic and growth-promoting actions directly...

journal_title：Endocrine journal

authors： Hashimoto R,Sakai K,Matsumoto H,Iwashita M

更新日期：2010-01-01 00:00:00

abstract：:Insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) are important for fetal and postnatal development, but the regulation of circulating IGFs and IGFBPs has not been as thoroughly investigated in the maternal/fetal unit as in the adult animal where nutrition status plays a regulatory role. We used t...

journal_title：Endocrine journal

authors： Lee WH,Gaylord TD,Bowsher RR,Hlaing M,Moorehead H,Liechty EA

更新日期：1997-02-01 00:00:00

abstract：:Gitelman syndrome (GS) is a salt-wasting tubulointerstitial disease of autosomal recessive inheritance (OMIM613395) caused by genic mutation of SLC12A3, which codes thiazide-sensitive Na-Cl cotransporter (NCCT) gene. The gene mutation of the majority of GS patients is compound heterozygous. This study analyzes two cas...

journal_title：Endocrine journal

authors： Luo J,Yang X,Liang J,Li W

更新日期：2015-01-01 00:00:00

abstract：:Fructose 2,6-bisphosphate (F2,6BP) is a powerful allosteric activator of 6-phosphofructo-1-kinase, which is the rate-limiting enzyme for glycolysis. Mitogenic stimulation of lymphocytes is related to an enhanced rate of glucose utilization and F2,6BP mediated activation of glycolysis. To determine the effect of hyperg...

journal_title：Endocrine journal

authors： Atsumi T,Chiba H,Yoshioka N,Bucala R,Koike T

更新日期：2007-08-01 00:00:00

abstract：:This is a case report of an 18-year-old man with central diabetes incipidus (DI). An MRI done three months after the onset of the DI did not disclose a responsible lesion. Four months later, a second MRI showed the location of the tumor origin at the upper pituitary stalk and median eminence. Eight months later, the t...

journal_title：Endocrine journal

authors： Saeki N,Uchida D,Tatsuno I,Saito Y,Yamaura A

更新日期：1999-04-01 00:00:00

abstract：:The extent of thyroidectomy in Graves' disease remains controversial. In our institution, long-term euthyroidism without thyroxin replacement therapy has been the aim, and it has long been the standard surgical procedure used to treat Graves' disease in many institutions, including our hospital. Based our several clin...

journal_title：Endocrine journal

authors： Sugino K,Nagahama M,Kitagawa W,Ohkuwa K,Uruno T,Matsuzu K,Suzuki A,Tomoda C,Y Hames K,Akaishi J,Masaki C,Ogimi Y,Yabuta T,Ito K

更新日期：2019-02-28 00:00:00

abstract：:This study assessed the dose-dependent efficacy and safety of exenatide over 12 weeks in Japanese patients with type 2 diabetes suboptimally controlled despite therapeutic doses of sulfonylurea (SU), SU plus biguanide, or SU plus thiazolidinedione. Patients were randomly assigned to placebo (N = 40), 2.5 microg (N = 3...

journal_title：Endocrine journal

authors： Kadowaki T,Namba M,Yamamura A,Sowa H,Wolka AM,Brodows RG

更新日期：2009-01-01 00:00:00

abstract：:Circulating anti-islet autoantibodies in sera are used as a predictive marker for type 1 diabetes (T1D). We here report two Japanese patients with autoimmune thyroid disease complicated with T1D in whom the time course of anti-islet autoantibodies were observed before the clinical onset of diabetes. Case 1: A woman wh...

journal_title：Endocrine journal

authors： Horie I,Kawasaki E,Shimomura A,Satoh T,Ueki I,Kuwahara H,Ando T,Abiru N,Usa T,Eguchi K

更新日期：2010-01-01 00:00:00

abstract：:In this study, we evaluated the association between bone mineral density (BMD) and 10 single-nucleotide polymorphisms (SNPs) within eight osteoporosis susceptibility genes that were previously identified in genome-wide association studies (GWASs). A total of 494 men and 493 postmenopausal women participating in the Ch...

journal_title：Endocrine journal

authors： Park SE,Oh KW,Lee WY,Baek KH,Yoon KH,Son HY,Lee WC,Kang MI

更新日期：2014-01-01 00:00:00

abstract：:The synthesis of nitric oxide (NO) has been demonstrated in the vascular endothelial cells and other tissues including in rat and bovine adrenal gland. To determine whether NO mediates aldosterone production in the adrenals, we evaluated the basal production of aldosterone, and the ACTH or angiotensin II (A II)-stimul...

journal_title：Endocrine journal

authors： Nakayama T,Izumi Y,Soma M,Kanmatsuse K

更新日期：1996-04-01 00:00:00

abstract：:We demonstrated severe hyponatremia in a 68 year-old man who had pituitary tumor. He had poor appetite and was disoriented. Tests revealed hyponatremia of 110 mmol/l, and he was admitted to Jichi Medical School Omiya Medical Center to undergo further tests. Physical findings revealed disturbance of consciousness with ...

journal_title：Endocrine journal

authors： Kanda M,Omori Y,Shinoda S,Yamauchi T,Tamemoto H,Kawakami M,Ishikawa SE

更新日期：2004-08-01 00:00:00

abstract：:Continuous subcutaneous insulin infusion (CSII) therapy using insulin pumps has become widely used in the treatment of type 1 diabetes mellitus (T1DM). This retrospective study aimed to assess the efficacy and safety of long-term insulin pump treatment in patients with T1DM aged ≥50 years. The study included patients ...

journal_title：Endocrine journal

authors： Matejko B,Krzyżowska S,Kieć-Wilk B,Malecki MT,Klupa T

更新日期：2020-03-28 00:00:00

abstract：:Endothelial dysfunction is considered to be an early event in the development of atherosclerosis. The present study was undertaken to evaluate endothelial function and biochemical markers in type 2 diabetes mellitus (T2DM) patients before and after treatment with or without pioglitazone (PIO). Forty-one T2DM patients ...

journal_title：Endocrine journal

authors： Tsuchiya K,Akaza I,Yoshimoto T,Hirata Y

更新日期：2009-01-01 00:00:00

abstract：:The inflammatory biomarkers that fully characterize the metabolically unhealthy (MU) state-which is a risk factor for cardiovascular disease (CVD)-remain unclear. Recent studies suggest follistatin-like protein 1 (FSTL1) could be used as a biomarker for inflammation and CVD, however there is little information on FSTL...

journal_title：Endocrine journal

authors： Lee SY,Kim DY,Kyung Kwak M,Hee Ahn S,Kim H,Kim BJ,Koh JM,Rhee Y,Hwa Kim C,Hyun Baek K,Min YK,Hun Lee S,Kang MI

更新日期：2019-03-28 00:00:00

abstract：:As a rare condition characterized by inflammation of the pituitary gland, hypophysitis usually results in hypopituitarism and pituitary enlargement. The most critical outcome of hypopituitarism is caused by secondary adrenal insufficiency. Glucocorticoid deficiency is a life-threatening condition, and patients who dev...

journal_title：Endocrine journal

authors： Aikawa E,Horie I,Naganobu K,Nozaki A,Kamada A,Abiru N,Kawakami A

更新日期：2020-11-28 00:00:00

abstract：:We describe here a patient with primary hyperparathyroidism who had high serum intact PTH levels for over 16 months after parathyroidectomy without signs of recurrence or persistence of the disease. The patient was a 48-year-old female who appeared well nourished (body mass index, 23.7). She was received subtotal gast...

journal_title：Endocrine journal

authors： Mimura Y,Kanauchi H,Ogawa T,Ohkura F,Kaminishi M

更新日期：1998-10-01 00:00:00

abstract：:In this study, we investigated the difference in lymph node-recurrence free survival (LN-RFS), distant recurrence-free survival (DRFS), and cause-specific survival (CSS) between patients with papillary thyroid carcinoma (PTC) in the entire group (Group I) and those with lymph node- and distant-recurrence-free survival...

journal_title：Endocrine journal

authors： Ito Y,Kudo T,Kihara M,Takamura Y,Kobayashi K,Miya A,Miyauchi A

更新日期：2012-01-01 00:00:00

abstract：:Nesfatin-1 is a polypeptide derived from the posttranslational processing of the N-terminal fragment of nucleobindin 2 (NUCB2), that was originally identified as an anorexigenic hypothalamic neuropeptide. A number of reports have recently shown that NUCB2/nesfatin-1 is widely expressed in various peripheral tissues, i...

journal_title：Endocrine journal

authors： Cao X,Liu XM,Zhou LH

更新日期：2013-01-01 00:00:00

abstract：:In this review, we focused on the patient age as an indicator of tumor growth and prognostic significance in both clinical papillary thyroid carcinoma (PTC) and subclinical papillary microcarcinoma (PMC: PTC ≤ 1 cm). In clinical PTC, young age (< 30 years) and old age (≥ 60 years) significantly affected the disease-fr...

journal_title：Endocrine journal

authors： Ito Y,Miyauchi A,Kobayashi K,Miya A

更新日期：2014-01-01 00:00:00