Abstract:
:Since the appearance of DDT-resistance in houseflies in 1947, over 30 mosquito species have developed resistance to this and other commonly used insecticides. Much knowledge has been gained concerning the mechanism of resistance in insects but, in general, this phenomenon cannot be explained in terms of a single factor common to all resistant species.Enzymic detoxication of DDT to DDE has been found in the study reported to be a major factor in the resistance of several mosquito species, particularly Aedes aegypti. However, such correlation could not be established in a highly DDT-resistant strain of Culex pipiens fatigans originating in Delhi, India. Furthermore, resistance of the latter strain to o-chloro-DDT and o,p-DDT cannot be attributed to a detoxication process since these compounds are refractory to dehydrochlorination both in vivo and in vitro. Quantitative data on metabolism of DDT derivatives are given and other possible mechanisms of resistance are discussed.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
Kalra RL,Perry AS,Miles JWsubject
Has Abstractpub_date
1967-01-01 00:00:00pages
651-6issue
4eissn
0042-9686issn
1564-0604journal_volume
37pub_type
杂志文章abstract::An attempt was made to assess the protective influence of killed intranasal influenza B vaccine against a homologous virus challenge. Two types of trial were performed. In the first of these, the vaccine was compared with an inert placebo and, in the second, with conventional homologous and heterologous parenteral vac...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1969-01-01 00:00:00
abstract::The author examines in detail the symptomatology, diagnosis, and treatment of plague, and outlines the problem of the length of the incubation period.The clinical features commonly met with in all severely-affected plague patients, regardless of the primary localization of the infection, are described. The author then...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1953-01-01 00:00:00
abstract:PROBLEM:Indoor residual spraying and long-lasting insecticidal nets (LLINs) are key tools for malaria vector control. Malawi has struggled to scale up indoor residual spraying and to improve LLIN coverage and usage. APPROACH:In 2002, the Malawian National Malaria Control Programme developed guidelines for insecticide ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.15.154245
更新日期:2016-06-01 00:00:00
abstract::The addition of Tween 80 to tuberculin dilutions as a stabilizer is known to increase the size of moderate and strong reactions but to reduce that of weak reactions. In order to find out whether this effect on reaction size is connected with the stabilizing action, a study was carried out to compare the reactions to t...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1965-01-01 00:00:00
abstract::Contributions made by five groups of investigators to the knowledge of the stability of different iodine compounds in salt, and of the extent of the losses of iodine which may occur when iodized salt is exposed to different conditions of storage and use, are discussed by the author.STABILITY OF THE IODINE COMPONENT IN...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1953-01-01 00:00:00
abstract::Catalina Devandas Aguilar talks to Stephanie Cheng about the impact of the 2008 Convention on the Rights of Persons with Disabilities, the importance of listening to people living with disabilities and what United Nations agencies can do to support their further empowerment. ...
journal_title:Bulletin of the World Health Organization
pub_type: 面试,新闻
doi:10.2471/BLT.19.030119
更新日期:2019-01-01 00:00:00
abstract::Previous work on monkeys and on human volunteers led to the development of a schedule of diethylcarbamazine dosage suitable for the chemoprophylaxis of loiasis. In several parts of Africa where this chemoprophylaxis is practised against Loa loa, infections with Onchocerca volvulus are also common. Attempts were theref...
journal_title:Bulletin of the World Health Organization
pub_type: 临床试验,杂志文章
doi:
更新日期:1968-01-01 00:00:00
abstract:OBJECTIVE:To assess the effect of tobacco smoking on the outcome of tuberculosis treatment in Tbilisi, Georgia. METHODS:We conducted a prospective cohort study of adults with laboratory-confirmed tuberculosis from May 2011 to November 2013. History of tobacco smoking was collected using a standardized questionnaire ad...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.14.147439
更新日期:2015-06-01 00:00:00
abstract::Highly sensitive case definitions were first introduced by national poliomyelitis eradication programmes to avoid missing true cases of the disease, though false-positive diagnostic errors could still occur owing to low specificity. Extensive data from all 1620 cases of acute, flaccid paralysis reported in Brazil duri...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::In order to study the role of genetic factors in susceptibility to leprosy infection, the prevalence of leprosy in 118 pairs of Burmese villages different distances apart was investigated. The distribution pattern of the correlation coefficients for leprosy rates was compared with that known to occur for genetic marke...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1973-01-01 00:00:00
abstract::In developing countries, chronic respiratory diseases represent a challenge to public health because of their frequency, severity, projected trends, and economic impact. Health care planners, for example, are faced with a dramatic increase in tobacco use and must establish priorities for the allocation of limited reso...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:To determine the fraction of individuals with high total serum cholesterol who get diagnosed and effectively treated in eight high- and middle-income countries. METHODS:Using data from nationally representative health examination surveys conducted in 1998-2007, we studied a probability sample of 79 039 adult...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.10.079947
更新日期:2011-02-01 00:00:00
abstract::Enzyme immunoassays represent in many cases the preferred procedure for the detection of antigens or corresponding antibodies. However, many of the current procedures are performed suboptimally. This article reviews the available designs, auxiliary recognition systems, production and purification of antibodies, conjug...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,评审
doi:
更新日期:1985-01-01 00:00:00
abstract::Individual patient care and programme evaluation are pivotal for the success of antiretroviral treatment programmes in resource-limited countries. While computer-aided documentation and data storage are indispensable for any large programme, several important issues need to be addressed including which data are to be ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/blt.04.019307
更新日期:2006-02-01 00:00:00
abstract::The basic problem in the study of tick-borne virus diseases is to establish where the virus is maintained in nature. In general, this focus will be found where there are large and relatively stable populations of ticks, small rodents and insectivores. In the Tribec region the principal vector of tick-borne encephaliti...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1967-01-01 00:00:00
abstract::In Iran, microscopic examination of skin scrapings from 2202 individuals with clinically diagnosed cutaneous leishmaniasis (CL) lesions revealed the presence of amastigotes in 1123 cases (51.0%). Bacteriological examinations of the lesions indicated that 788 individuals (35.7%) were also infected with one or more path...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::The treatment of cholera with bacteriophage has, in the past, been unsuccessful, owing to the fact that the phages prepared by the usual method (multiplication on cholera vibrios in broth) proved incapable of parasitizing cholera vibrios in vivo. In this paper, the author presents the results of therapeutic and prophy...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1963-01-01 00:00:00
abstract::Pacific islanders face up to the dire health effects of global warming. Atasa Moceituba and Monique Tsang report. ...
journal_title:Bulletin of the World Health Organization
pub_type: 新闻
doi:10.2471/BLT.15.021115
更新日期:2015-11-01 00:00:00
abstract::Bringing together various disease-specific guidelines for sick children, WHO and UNICEF have developed an Integrated Management of Childhood Illness (IMCI) algorithm, one component of which (assess and classify) was tested in the outpatient department of a rural district hospital in western Uganda. Children aged 2-59 ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::Recent investigations have revealed that monkeypox virus infections occur with a high prevalence in several species of squirrels belonging to the genus Funisciurus, less frequently in squirrels of the genus Heliosciurus, and rarely in forest-dwelling primates. These squirrels commonly inhabit the secondary forests aro...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1988-01-01 00:00:00
abstract::The association between oral leukoplakia and possible etiological factors in patients at a Bombay hospital was analysed by a new multivariate computer analysis based on information theory. It was found that the most important etiological factors were bidi smoking and age. The well known sex-leukoplakia relationship wa...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1972-01-01 00:00:00
abstract::Cardiomyopathies are certain heart diseases of unknown etiology and pathogenesis, occurring mostly in tropical and subtropical areas, where they constitute a major clinical problem and sometimes a public health problem. The need for international co-operation in the study of such forms of heart disease has long been r...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1968-01-01 00:00:00
abstract:Objective:To estimate the use of hospitals for four essential primary care services offered in health centres in low- and middle-income countries and to explore differences in quality between hospitals and health centres. Methods:We extracted data from all demographic and health surveys conducted since 2010 on the typ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.19.245563
更新日期:2020-11-01 00:00:00
abstract::A number of drugs and drug combinations were tested both in vitro and in vivo against pathogens causing actinomycetoma and maduromycetoma. Of 144 patients with actinomycetoma treated, 63.2% were cured, 21.5% showed great improvement in their condition, and 11.1% showed some improvement. Treatment was successful even w...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::In this paper an analysis of genetic recombinants derived from crosses between two mutant stocks of Vibrio cholerae, strain 162, differing from one another in nutritional requirements and other characters, is presented. It is shown that parent strains possessing a fertility factor (designated as the P factor) function...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1964-01-01 00:00:00
abstract:OBJECTIVE:To estimate the prevalence of diabetes and prediabetes in Bangladesh using national survey data and to identify risk factors. METHODS:Sociodemographic and anthropometric data and data on blood pressure and blood glucose levels were obtained for 7541 adults aged 35 years or more from the biomarker sample of t...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.13.128371
更新日期:2014-03-01 00:00:00
abstract::Haematological surveys of adult population samples were conducted simultaneously in 12 countries, all but one of which are in Europe. Haematological estimations on samples from nine of the countries were made in one central laboratory. Differences between countries in the mean levels of haemoglobin (and haematocrit an...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::Sera were collected from 320 shearwaters (Puffinus pacificus chlororhynchus) nesting on two islands off the east coast of northern Australia in December 1969. About 10% of these sera specifically inhibited the neuraminidase of the 1957 strain of human influenza (A2/Asian/57), some to high titre.The neuraminidase of A2...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1970-01-01 00:00:00
abstract::The HemoCue system utilizes the principle of oxidation of haemoglobin to hemiglobin by sodium nitrite and the subsequent conversion of hemiglobin to hemiglobinazide by sodium azide. The reagents for these reactions are contained within a small disposable microcuvette of approximately 10 microliters in volume. A venous...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::Kenya's Constitution of 2010 triggered a cascade of reforms across all sectors to align with new constitutional standards, including devolution and a comprehensive bill of rights. The constitution acts as a platform to advance health rights and to restructure policy, legal, institutional and regulatory frameworks towa...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.19.237297
更新日期:2020-10-01 00:00:00