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Measuring and optimizing results in multipolar RFA: Techniques and early findings in an experimental setting.

Abstract：

:Radiofrequency ablation (RFA) has shown to be a reasonable alternative for the treatment of hepatic tumors and metastases although multiple limitations remain. Cooling effects due to larger vessels can prevent complete coverage and may lead to early tumor relapse. This preliminary in vivo pig study combines the use of multipolar RFA with three applicators (six electrodes) and interrupted liver perfusion using Pringle's maneuver to overcome the most serious limitations. Furthermore, immediate detection of incomplete RFA is important to revise ablation. We used contrast enhanced computed tomography (CECT) to evaluate post ablation results in comparison to macroscopic images in healthy pig liver. We found significantly (p = 0.001) larger ablation zones and no affection by larger vessels with interrupted liver perfusion. This allows effective RFA for larger tumors. Immediate postinterventional CECT provided comparable results (r = 0.985) to macroscopic evaluation.

journal_name

Clin Hemorheol Microcirc

journal_title

Clinical hemorheology and microcirculation

authors

Vahldiek JL,Lehmann KS,Poch F,Zurbuchen U,Kreis ME,Gemeinhardt O,Hamm B,Niehues SM

doi

10.3233/CH-141886

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

77-87

issue

1

eissn

1386-0291

issn

1875-8622

pii

9666234V0796K214

journal_volume

58

pub_type

杂志文章

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