Antileukocyte antibody in postpartum and renal transplant subjects. A comparison of capillary agglutination and lymphocytotoxicity reactions.

abstract：:There is considerable current interest in the possibility that long-term graft acceptance in clinical solid-organ transplantation might be dependent upon the development of a microchimeric state between the donor and recipient. This possibility has been prompted by the observation that in some transplant patients cell...

journal_title：Transplantation

authors： Bushell A,Pearson TC,Morris PJ,Wood KJ

更新日期：1995-05-27 00:00:00

abstract：BACKGROUND:The current shortage of organ donors has led many centers to use marginal and nonheart-beating donors (NHBDs). Recent research has implicated the infiltration of lymphocytes as an important mediator of ischemia-reperfusion injury (IRI). FTY720 is an immunosuppressant that promotes lymphocyte sequestration in...

journal_title：Transplantation

authors： Delbridge MS,Shrestha BM,Raftery AT,El Nahas AM,Haylor JL

更新日期：2007-07-27 00:00:00

abstract：:A technique for orthotopic bone transplantation in mice has been developed. A section of recipient tibia was removed and replaced by a similar section from the donor animal. The graft was held in place by internal fixation. Bone healing was assessed clinically, histologically, radiologically, and by torsion testing. T...

journal_title：Transplantation

authors： Halloran PF,Ziv I,Lee EH,Langer F,Pritzker KP,Gross AE

更新日期：1979-06-01 00:00:00

abstract：:This study investigates the possibility that the active enhancing properties of bone marrow (BM) cells may be related to Ia-like determinants on their surface membranes. Less chromium was released on a cell per cell basis from nucleated baboon BM cells used as targets in complement-dependent cytotoxicity than from lab...

journal_title：Transplantation

authors： Smit JA,Myburgh JA,Gaillard VJ

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:Alcoholic liver disease has emerged as a leading indication for hepatic transplantation, although it is a controversial use of resources. We aimed to examine all aspects of liver transplantation associated with alcohol abuse. METHODS:Retrospective cohort analysis of 123 alcoholic patients with a median of 7...

journal_title：Transplantation

authors： Bellamy CO,DiMartini AM,Ruppert K,Jain A,Dodson F,Torbenson M,Starzl TE,Fung JJ,Demetris AJ

更新日期：2001-08-27 00:00:00

abstract：:To gain insight into the contribution of immunologic and hemodynamic factors in the progressive demise of structure and function in chronic renal allograft dysfunction, we studied the histological changes, the immunostainable glomerular anionic sites, and glomerular capillary hydrostatic pressures of rat renal allogra...

journal_title：Transplantation

authors： Benediktsson H,Chea R,Davidoff A,Paul LC

更新日期：1996-12-15 00:00:00

abstract：:The mortality rates for CVDs in transplant recipients are greater than those in the general population (13). CVDs are a major cause of both patient and graft loss in renal transplant recipients, and improving cardiovascular health may help to extend both patient and graft survival. A complication of chronic renal fail...

journal_title：Transplantation

authors： Wheeler DC,Steiger J

更新日期：2000-12-15 00:00:00

abstract：:Solid organ and allogeneic hematopoietic cell transplantation have become standard therapeutic interventions that save patient lives and improve quality of life. Our enhanced understanding of transplantation immunobiology has refined clinical management and improved outcomes. However, organ rejection and graft-versus-...

journal_title：Transplantation

authors： Radojcic V,Maillard I

更新日期：2016-12-01 00:00:00

abstract：:Patient entry is now complete in a prospective trial of anti-Tac, a murine IgG2a monoclonal antibody directed against the p55 chain of the human IL-2 receptor, for the prevention of renal allograft rejection. Recipients of primary cadaver allografts were randomized to receive either anti-Tac (20 mg q.d. x 10 days begi...

journal_title：Transplantation

authors： Kirkman RL,Shapiro ME,Carpenter CB,McKay DB,Milford EL,Ramos EL,Tilney NL,Waldmann TA,Zimmerman CE,Strom TB

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Registry databases offer the statistical power to analyze differences in graft survival rates that may not be detected in randomized clinical trials. This study analyses 2-year graft survival using tacrolimus (tac) or cyclosporine (CsA) with mycophenolate mofetil (MMF) and steroids. METHODS:Data reported to...

journal_title：Transplantation

authors： Bunnapradist S,Daswani A,Takemoto SK

更新日期：2003-07-15 00:00:00

abstract：:Lethally irradiated (850 rads) DBA/2 mice which had been transplanted 10 months previously with 2 times 10-6 bone marrow cells from 3-week-old donors of the H-2-histocompatible NZB, BALB/c and DBA/2 strains were examined for manifestations of autoimmune disease. Also studied were lethally irradiated (950 rads) NZB mic...

journal_title：Transplantation

authors： Morton JI,Siegel BV,Moore RD

更新日期：1975-06-01 00:00:00

abstract：:In light of the transplant community's efforts to increase living donation, preserving donor autonomy is essential. Understanding how often and the reasons why potential living kidney donors opt out of the donor evaluation process for nonmedical reasons is important for assessing donor voluntariness. The experiences o...

journal_title：Transplantation

authors： Thiessen C,Kulkarni S,Reese PP,Gordon EJ

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Combined treatments of mycophenolate mofetil (MMF) and losartan (LSRT) have synergistic effects on various renal diseases through their hemodynamic and anti-inflammatory effects. This study investigated whether MMF treatment is effective in inhibiting inflammatory processes in chronic cyclosporine A (CsA) ne...

journal_title：Transplantation

authors： Yang CW,Ahn HJ,Kim WY,Li C,Jung JY,Yoon SA,Kim YS,Cha JH,Kim J,Bang BK

更新日期：2003-02-15 00:00:00

abstract：:The aim of this study was to investigate the combined effect of DLA matching and immunosuppressive therapy on the survival of segmental small-bowel allografts in dogs. Orthotopic segmental small-bowel transplantations (25 to 30% of total small bowel length) were performed in two stages: first a heterotopic segmental s...

journal_title：Transplantation

authors： Meijssen MA,Heineman E,de Bruin RW,Wolvekamp MC,Marquet RL,Molenaar JC

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:An elevated terminal creatinine is frequently used as a reason for organ refusal in pediatric kidney transplantation. There is increasing evidence that adults who receive kidneys from donors with moderate to severe acute kidney injury (AKI) have similar outcomes to recipients who receive kidneys from donors ...

journal_title：Transplantation

authors： Solomon S,Hayde N

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Remote ischemic preconditioning (RIPC) protects against liver ischemia reperfusion (IR) injury. An essential circulating mediator of this protection is nitric oxide (NO) induced by lower limb RIPC. One of the mechanisms through which NO generally acts is the soluble guanylyl cyclase-cyclic GMP (sGC-cGMP) pat...

journal_title：Transplantation

authors： Abu-Amara M,Yang SY,Quaglia A,Rowley P,Tapuria N,Fuller B,Davidson B,Seifalian A

更新日期：2012-05-15 00:00:00

abstract：BACKGROUND:The authors studied the relationship between the dynamics of Epstein-Barr virus (EBV) load, CD8 T-cell activation and differentiation, and EBV-associated symptoms in 25 children after kidney transplantation (Tx). METHODS:Twenty-two patients were enrolled at the time of Tx and three at diagnosis of EBV-induc...

journal_title：Transplantation

authors： Baudouin V,Dehée A,Pédron-Grossetete B,Ansart-Pirenne H,Haddad E,Maisin A,Loirat C,Sterkers G

更新日期：2004-06-15 00:00:00

abstract：BACKGROUND:Transplant medicine's impact on America's public health is seriously limited by acute shortage of transplantable organs. Consequently, the United Sates has witnessed considerable investment in the promotion of organ donor registries. Although there is no evidence to support that donor registry promotion alle...

journal_title：Transplantation

authors： Razdan M,Smith KJ,Bryce CL,Degenholtz HB

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Diarrhea is a frequent complication of solid organ transplantation. Cryptosporidiosis is classically reported in patients with acquired immunodeficiency syndrome and emerged as a cause of persistent diarrhea in solid organ transplant patients. METHODS:Through the ANOFEL Cryptosporidium National Network and ...

journal_title：Transplantation

authors： Lanternier F,Amazzough K,Favennec L,Mamzer-Bruneel MF,Abdoul H,Tourret J,Decramer S,Zuber J,Scemla A,Legendre C,Lortholary O,Bougnoux ME,ANOFEL Cryptosporidium National Network and Transplant Cryptosporidium Study Group.

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:As T-cell receptor-major histocompatibility complex (MHC) class I/self peptide interaction regulates T-cell development in the thymus, we reasoned that presentation of peptides by self dendritic cells (DC) to developing T cells in the thymus might induce acquired thymic tolerance. This hypothesis is based on...

journal_title：Transplantation

authors： Ali A,Garrovillo M,Jin MX,Hardy MA,Oluwole SF

更新日期：2000-01-27 00:00:00

abstract：:Pulmonary thrombus formation in the region of atrial anastomosis following lung transplantation has been reported by several authors. Such patients typically present immediately after surgery with significant hemodynamic compromise causing pulmonary edema and hypoxemia. We describe a patient who presented with bilater...

journal_title：Transplantation

authors： Stang MR,Hinderliter AL,Gott KK,Paradowski LJ,Aris RM

更新日期：1996-09-15 00:00:00

abstract：BACKGROUND:The incidence of stroke and risk factors for different subtypes of cerebrovascular (CBV) events in renal transplant recipients have not been examined in any large prospective controlled trial. METHODS:The Assessment of Lescol in Renal Transplantation was a randomized, double-blind, placebo-controlled study ...

journal_title：Transplantation

authors： Abedini S,Holme I,Fellström B,Jardine A,Cole E,Maes B,Holdaas H,ALERT Study Group.

更新日期：2009-01-15 00:00:00

abstract：:Transient pure red cell aplasia (PRCA) in three consecutive patients receiving ATG for management of kidney graft rejection prompted a systematic study of the effects on erythropoiesis of the ATG preparation used at our institution. We found that 90% of patients treated with rabbit anti-T lymphoblast globulin develope...

journal_title：Transplantation

authors： Schaffner A,Thomann B,Zala GF,Rüegg R,Keusch G,Fehr J,Gmür J

更新日期：1991-05-01 00:00:00

abstract：:Multiple pretransplant sera obtained from alloimmunized renal transplant recipients were tested for the presence of antiidiotypic-like antibodies (AB2) that inhibit donor-specific HLA antibodies in the microlymphocytotoxicity assay. Fourteen patients received repetitive single-donor blood transfusions (SDT). In this p...

journal_title：Transplantation

authors： Phelan DL,Rodey GE,Anderson CB

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:In the hamster to rat xenogeneic combination, antibodies, T cells, and natural killer (NK) cells have all been implicated in the process of rejection. 3.2.3 is a mouse IgG1kappa monoclonal antibody (mAb) directed against NKR-P1A on rat NK cells. The purpose of this study was to evaluate the effect of this mA...

journal_title：Transplantation

authors： Gourlay WA,Chambers WH,Monaco AP,Maki T

更新日期：1998-03-15 00:00:00

abstract：BACKGROUND:Motexafin lutetium (Lu-Tex) is a photodynamic therapy (PDT) agent that localizes in atheromatous plaque in which it can be activated by far-red light. Lu-Tex biolocalization was examined in graft coronary artery disease (GCAD) with a rodent allograft model. After photoactivation, the effect on intimal prolif...

journal_title：Transplantation

authors： Yamaguchi A,Woodburn KW,Hayase M,Hoyt G,Robbins RC

更新日期：2001-06-15 00:00:00

abstract：BACKGROUND:The risk associated with transplantation of renal allografts from hepatitis B virus core antibody-positive (HBcAb(+)), hepatitis B virus surface antigen-negative (HBsAg(-)) donors is not well defined. METHODS:Over 4 years, we performed 45 kidney transplants from IgG HBcAb(+), IgM HBcAb(-), HBsAg(-) donors i...

journal_title：Transplantation

authors： Madayag RM,Johnson LB,Bartlett ST,Schweitzer EJ,Constantine NT,McCarter RJ Jr,Kuo PC,Keay S,Oldach DW

更新日期：1997-12-27 00:00:00

abstract：BACKGROUND:Bone marrow cells (BMCs) are believed to have the ability to generate functional hepatocytes and have some merits as a therapeutic modality for metabolic liver diseases. However, the appearance of BMC-derived hepatocytes (BMDHs) is low. We hypothesized that early BMC injection would be feasible for creating ...

journal_title：Transplantation

authors： Misawa R,Soeda J,Ise H,Takahashi M,Kubota K,Mita A,Nakata T,Miyagawa S

更新日期：2009-04-27 00:00:00

abstract：:It has been reported that the response to alloantigens presented by the direct and indirect pathway may be of differential relevance after human kidney transplantation. Accordingly, we monitored these routes in peripheral blood mononuclear cells (PBMC) of heart transplant patients from before transplantation and up to...

journal_title：Transplantation

authors： van Besouw NM,Vaessen LM,Daane CR,Jutte NH,Balk AH,Claas FH,Weimar W

更新日期：1996-01-15 00:00:00

abstract：BACKGROUND:Sotrastaurin (STN), a novel oral protein kinase C inhibitor that inhibits early T-cell activation, was assessed in non-human primate recipients of life-supporting kidney allografts. METHODS:Cynomolgus monkey recipients of life-supporting kidney allografts were treated orally with STN alone or in combination...

journal_title：Transplantation

authors： Bigaud M,Wieczorek G,Beerli C,Audet M,Blancher A,Heusser C,Morris RE,Wagner J

更新日期：2012-01-27 00:00:00