Muscle enzymatic changes induced by blockage of axoplasmic transport.

abstract：:Humans and animals value the opportunity to choose by preferring alternatives that offer more rather than fewer choices. This preference for choice may arise not only from an increased probability of obtaining preferred outcomes but also from the freedom it provides. We used human neuroimaging to investigate the neura...

journal_title：Journal of neurophysiology

authors： Fujiwara J,Usui N,Park SQ,Williams T,Iijima T,Taira M,Tsutsui K,Tobler PN

更新日期：2013-10-01 00:00:00

abstract：:Motor-unit synchronization, which is a measure of the near simultaneous discharge of action potentials by motor units, has the potential to influence spike-triggered average force and the steadiness of a low-force isometric contraction. The purpose of the study was to estimate the contribution of motor-unit synchroniz...

journal_title：Journal of neurophysiology

authors： Semmler JG,Steege JW,Kornatz KW,Enoka RM

更新日期：2000-07-01 00:00:00

abstract：:1. The effects of inhibitory postsynaptic potential (IPSP) barrages on coding of sinusoidal length inputs were investigated in slowly and rapidly adapting stretch receptors of crayfish (RM1 and RM2, respectively). To examine the contribution of postsynaptic firings, a description was obtained of the temporal correlati...

journal_title：Journal of neurophysiology

authors： Barrio LC,Buño W

更新日期：1990-06-01 00:00:00

abstract：:The spike-triggered averaging technique (26) was used to determine whether the synaptic input from medial gastrocnemius (MG) Ia-afferent fibers to homonymous motoneurons is "topographically weighted" (22) by means of differences in projection frequency, excitatory postsynaptic potential (EPSP) amplitude, or a combinat...

journal_title：Journal of neurophysiology

authors： Lucas SM,Cope TC,Binder MD

更新日期：1984-01-01 00:00:00

abstract：:The contributions of the hyperpolarization-activated current, I(h), to generation of rhythmic activities are well described for various central neurons, particularly in thalamocortical circuits. In the present study, we investigated effects of a general anesthetic, propofol, on native I(h) in neurons of thalamus and c...

journal_title：Journal of neurophysiology

authors： Chen X,Shu S,Bayliss DA

更新日期：2005-12-01 00:00:00

abstract：:1. A quantal analysis of transmission at the identified molluscan synapse, V2-RPr1, was performed during development. The study was intended to determine the pre- and postsynaptic contributions to the marked changes in transmitter release described in the previous report. 2. The success of the quantal analysis was pre...

journal_title：Journal of neurophysiology

authors： Pawson PA,Chase R

更新日期：1988-12-01 00:00:00

abstract：:The characteristics of the primary afferent depolarization (PAD) of Ia- and Ib-fibers generated by segmental and descending inputs have been analyzed in the spinal cord of anesthetized cats. The PAD was inferred from the changes produced by conditioning inputs on the intraspinal stimulus current required to produce a ...

journal_title：Journal of neurophysiology

authors： Rudomin P,Solodkin M,Jiménez I

更新日期：1986-10-01 00:00:00

abstract：:Rod signals traverse several synapses en route to cone bipolar cells. In one pathway, rods communicate directly with cones via gap junctions. In a second pathway, signals flow rods-rod bipolars-AII amacrines-cone bipolars. The relative contribution of each pathway to retinal function is not well understood. Here we ha...

journal_title：Journal of neurophysiology

authors： Trexler EB,Li W,Massey SC

更新日期：2005-03-01 00:00:00

abstract：:1. Action potentials of crayfish claw motor neurons were recorded during both imposed constant-velocity displacements and imposed alternating sequences of opening and closing step movements of the dactyl. 2. Peristimulus time (PST) histograms show that the firing probabilities of two neurons, the opener inhibitor (OI)...

journal_title：Journal of neurophysiology

authors： Lindsey BG,Gerstein GL

更新日期：1979-03-01 00:00:00

abstract：:Apical dendrites of layer 5 pyramidal cells in a slice preparation of rat sensorimotor cortex were depolarized focally by long-lasting glutamate iontophoresis while recording intracellularly from their soma. In most cells the firing pattern evoked by the smallest dendritic depolarization that evoked spikes consisted o...

journal_title：Journal of neurophysiology

authors： Schwindt P,Crill W

更新日期：1999-03-01 00:00:00

abstract：:In mesial temporal lobe (MTL) epilepsy, which typically involves the hippocampus (HPC), epileptiform events are enhanced during slow wave sleep (SWS). It remains unclear how and why the electroencephalographic (EEG) states that constitute SWS might predispose the HPC to this type of pathological activity. Recently our...

journal_title：Journal of neurophysiology

authors： Nazer F,Dickson CT

更新日期：2009-09-01 00:00:00

abstract：:The whisker region in the rodent primary motor (MI) cortex receives dense projections from neurons aligned with the layer IV septa in the whisker region of the primary somatosensory (SI) cortex. To compare whisker-induced responses in MI with respect to the SI responses in the septa and adjoining barrel regions, we us...

journal_title：Journal of neurophysiology

authors： Chakrabarti S,Zhang M,Alloway KD

更新日期：2008-07-01 00:00:00

abstract：:The capabilities of any sensory system are ultimately constrained by the properties of the sensory neurons: the ability to detect and represent stimuli is limited by noise due to spontaneous activity, and optimal decoding in downstream circuitry must be matched to the nature of the encoding performed at the input. Her...

journal_title：Journal of neurophysiology

authors： Arnson HA,Holy TE

更新日期：2011-07-01 00:00:00

abstract：:Using extra- and intracellular recording techniques, we investigated the epileptiform activity induced by low concentrations (5 and 10 microM) of bath-applied 4-aminopyridine (4-AP) in the CA3 subfield of rat hippocampal slices. We also studied the effects of 4-AP on the excitatory and inhibitory synaptic conductance ...

journal_title：Journal of neurophysiology

authors： Rutecki PA,Lebeda FJ,Johnston D

更新日期：1987-06-01 00:00:00

abstract：:1. The simplicity of the jellyfish nervous system makes it an ideal preparation to assess the contributions of different ion channels to behavior. In the giant motor axons of the jellyfish Aglantha digitale, low-threshold spikes elicit slow swimming, whereas escape swimming depends on a higher-threshold, overshooting ...

journal_title：Journal of neurophysiology

authors： Meech RW,Mackie GO

更新日期：1993-03-01 00:00:00

abstract：:Divergence of the Shaker superfamily of voltage-gated (Kv) ion channels early in metazoan evolution created numerous electrical phenotypes that were presumably selected to produce a wide range of excitability characteristics in neurons, myocytes, and other cells. A comparative approach that emphasizes this early radia...

journal_title：Journal of neurophysiology

authors： Klassen TL,Buckingham SD,Atherton DM,Dacks JB,Gallin WJ,Spencer AN

更新日期：2006-05-01 00:00:00

abstract：:Attention is known to affect the response properties of sensory neurons in visual cortex. These effects have been traditionally classified into two categories: 1) changes in the gain (overall amplitude) of the response; and 2) changes in the tuning (selectivity) of the response. We performed an extensive series of beh...

journal_title：Journal of neurophysiology

authors： Paltoglou AE,Neri P

更新日期：2012-03-01 00:00:00

abstract：:Proteinase-activated receptors (PARs) have a unique activation mechanism in that a proteolytically exposed N-terminal region acts as a tethered ligand. A potential impact of PAR on sensory processing has not been fully examined yet. Here we report that synthetic peptides with sequences corresponding to PAR ligands enh...

journal_title：Journal of neurophysiology

authors： Fujita T,Liu T,Nakatsuka T,Kumamoto E

更新日期：2009-07-01 00:00:00

abstract：:Abductor hallucis is the largest muscle in the arch of the human foot and comprises few motor units relative to its physiological cross-sectional area. It has been described as a postural muscle, aiding in the stabilization of the longitudinal arch during stance and gait. The purpose of this study was to describe the ...

journal_title：Journal of neurophysiology

authors： Kelly LA,Racinais S,Cresswell AG

更新日期：2013-08-01 00:00:00

abstract：:The primate superior colliculus (SC) is causally involved in microsaccade generation. Moreover, visually responsive SC neurons across this structure's topographic map, even at peripheral eccentricities much larger than the tiny microsaccade amplitudes, exhibit significant modulations of evoked response sensitivity whe...

journal_title：Journal of neurophysiology

authors： Khademi F,Chen CY,Hafed ZM

更新日期：2020-06-01 00:00:00

abstract：:1. A method is described for measuring contractile properties of single human motor units. Conventional human microneurographic techniques were adapted to stimulate individual motor axons in the median nerve, with the use of negative current pulses and a tungsten microelectrode, while recording motor-unit electromyogr...

journal_title：Journal of neurophysiology

authors： Westling G,Johansson RS,Thomas CK,Bigland-Ritchie B

更新日期：1990-10-01 00:00:00

abstract：:There is considerable research on the neurobiological mechanisms within the hippocampal system that support spatial navigation. In this article I review the literature on navigational strategies in humans and animals, observations on hippocampal function in navigation, and studies of hippocampal neural activity in ani...

journal_title：Journal of neurophysiology

authors： Eichenbaum H

更新日期：2017-04-01 00:00:00

abstract：:GSG1L is an AMPA receptor (AMPAR) auxiliary subunit that regulates AMPAR trafficking and function in hippocampal CA1 pyramidal neurons. However, its physiological roles in other types of neurons remain to be characterized. Here, we investigated the role of GSG1L in hippocampal dentate granule cells and found that GSG1...

journal_title：Journal of neurophysiology

authors： Mao X,Gu X,Lu W

更新日期：2017-01-01 00:00:00

abstract：:Primary afferent fibers from the electroreceptors of mormyrid electric fish use a latency code to signal the intensity of electrical current evoked by the fish's own electric organ discharge (EOD). The afferent fibers terminate centrally in the deep and superficial granular layers of the electrosensory lobe with morph...

journal_title：Journal of neurophysiology

authors： Zhang J,Han VZ,Meek J,Bell CC

更新日期：2007-03-01 00:00:00

abstract：:1. We studied the effect of temporarily inhibiting neurons in the caudal fastigial nucleus in two rhesus macaques trained to make saccades to jumping targets. We placed injections of the gamma-aminobutyric acid (GABA) agonist muscimol unilaterally or bilaterally at sites in the caudal fastigial nucleus where we had re...

journal_title：Journal of neurophysiology

authors： Robinson FR,Straube A,Fuchs AF

更新日期：1993-11-01 00:00:00

abstract：:The human auditory system has an exceptional ability to separate competing sounds, but the neural mechanisms that underlie this ability are not understood. Responses of inferior colliculus (IC) neurons to "mistuned" complex tones were measured to investigate possible neural mechanisms for spectral segregation. A mistu...

journal_title：Journal of neurophysiology

authors： Sinex DG,Li H,Velenovsky DS

更新日期：2005-11-01 00:00:00

abstract：:Cross-orientation suppression was measured in human primary visual cortex (V1) to test the normalization model. Subjects viewed vertical target gratings (of varying contrasts) with or without a superimposed horizontal mask grating (fixed contrast). We used functional magnetic resonance imaging (fMRI) to measure the ac...

journal_title：Journal of neurophysiology

authors： Brouwer GJ,Heeger DJ

更新日期：2011-11-01 00:00:00

abstract：:The ventromedial medulla is implicated in a variety of functions including nociceptive and cardiovascular modulation and the control of thermoregulation. To determine whether single microinjections into the ventromedial medulla elicit changes in one or multiple functional systems, the GABA(A) receptor antagonist bicuc...

journal_title：Journal of neurophysiology

authors： Nason MW Jr,Mason P

更新日期：2004-07-01 00:00:00

abstract：:Action potential firing rates are generally limited by the refractory period, which depends on the recovery from inactivation of voltage-gated Na channels. In cerebellar Purkinje neurons, the kinetics of Na channels appear specialized for rapid firing. Upon depolarization, an endogenous open-channel blocker rapidly te...

journal_title：Journal of neurophysiology

authors： Afshari FS,Ptak K,Khaliq ZM,Grieco TM,Slater NT,McCrimmon DR,Raman IM

更新日期：2004-11-01 00:00:00

abstract：:Cortical neurons display two fundamental nonlinear response characteristics: contrast-set gain control (also termed contrast normalization) and response expansion (also termed half-squaring). These nonlinearities could play an important role in forming and maintaining stimulus selectivity during natural viewing, but o...

journal_title：Journal of neurophysiology

authors： Albrecht DG,Geisler WS,Frazor RA,Crane AM

更新日期：2002-08-01 00:00:00