The role of the hippocampus in navigation is memory.

abstract：:Electrophysiological analysis has revealed much about the broad coding and neural ensemble dynamics that characterize gustatory cortical (GC) taste processing in awake rats and about how these dynamics relate to behavior. With regard to mice, however, data concerning cortical taste coding have largely been restricted ...

journal_title：Journal of neurophysiology

authors： Levitan D,Lin JY,Wachutka J,Mukherjee N,Nelson SB,Katz DB

更新日期：2019-10-01 00:00:00

abstract：:The discharge patterns of single units in the ventral cochlear nucleus (VCN) of anesthetized guinea pigs were examined in response to iterated rippled noise (IRN) as a function of the IRN delay (which determines the IRN pitch) and the IRN sound level. Delays were varied over five octaves in half-octave steps, and soun...

journal_title：Journal of neurophysiology

authors： Wiegrebe L,Winter IM

更新日期：2001-03-01 00:00:00

abstract：:The R6/2 mouse is the most frequently used model for experimental and preclinical drug trials in Huntington's disease (HD). When the R6/2 mouse was first developed, it carried exon 1 of the huntingtin gene with ~150 cytosine-adenine-guanine (CAG) repeats. The model presented with a rapid and aggressive phenotype that ...

journal_title：Journal of neurophysiology

authors： Cummings DM,Alaghband Y,Hickey MA,Joshi PR,Hong SC,Zhu C,Ando TK,André VM,Cepeda C,Watson JB,Levine MS

更新日期：2012-01-01 00:00:00

abstract：:We constantly make eye movements to bring objects of interest onto the fovea for more detailed processing. Activity in area V4, a prestriate visual area, is enhanced at the location corresponding to the target of an eye movement. However, the precise role of activity in V4 in relation to these saccades and the modulat...

journal_title：Journal of neurophysiology

authors： Gee AL,Ipata AE,Goldberg ME

更新日期：2010-10-01 00:00:00

abstract：:Basal ganglia circuits are organized as parallel loops that have been proposed to compete in a winner-take-all fashion to determine the appropriate behavioral outcome. However, limited experimental support for strong lateral inhibition mechanisms within striatal regions questions this model. Here, stimulation of the p...

journal_title：Journal of neurophysiology

authors： Gruber AJ,Powell EM,O'Donnell P

更新日期：2009-04-01 00:00:00

abstract：:1. It is widely believed that signals contributing to the receptive field surrounds of retinal bipolar cells pass from horizontal cells to bipolar cells via GABAergic synapses. To test this notion, we applied gamma-aminobutyric acid (GABA) agonists and antagonists to isolated, perfused retinas of the salamander Ambyst...

journal_title：Journal of neurophysiology

authors： Hare WA,Owen WG

更新日期：1996-09-01 00:00:00

abstract：:Cell-surface glutamate transporters are essential for the proper function of early cortical networks because their dysfunction induces seizures in the newborn rat in vivo. We have now analyzed the consequences of their inhibition by DL-TBOA on the activity of the developing CA1 rat hippocampal network in vitro. DL-TBO...

journal_title：Journal of neurophysiology

authors： Cattani AA,Bonfardin VD,Represa A,Ben-Ari Y,Aniksztejn L

更新日期：2007-10-01 00:00:00

abstract：:Long-term potentiation (LTP) in rat spinal dorsal horn neurons was induced by electrical high-frequency stimulation (HFS) of afferent C fibers. LTP is generally assumed to be a key mechanism of spinal sensitization. To determine the contribution of skin and muscle afferents to LTP induction, the sural nerve (SU, pure ...

journal_title：Journal of neurophysiology

authors： Zhang J,Hoheisel U,Klein T,Magerl W,Mense S,Treede RD

更新日期：2016-02-01 00:00:00

abstract：:We investigated adaptation to simple force field scaling to determine whether the same strategy is used as during adaptation to more complex changes in the mechanical environment. Subjects initially trained in a force field, consisting of a rightward lateral force with a parabolic spatial profile (PF). The field stren...

journal_title：Journal of neurophysiology

authors： Hinder MR,Milner TE

更新日期：2007-11-01 00:00:00

abstract：:The primate superior colliculus (SC) is causally involved in microsaccade generation. Moreover, visually responsive SC neurons across this structure's topographic map, even at peripheral eccentricities much larger than the tiny microsaccade amplitudes, exhibit significant modulations of evoked response sensitivity whe...

journal_title：Journal of neurophysiology

authors： Khademi F,Chen CY,Hafed ZM

更新日期：2020-06-01 00:00:00

abstract：:Somatic sensory neurons of the dorsal root ganglia are necessary for a large part of our mechanosensory experience. However, we only have a good knowledge of the molecules required for mechanotransduction in simple invertebrates such as the nematode Caenorhabiditis elegans. In C. elegans, a number of so-called mec gen...

journal_title：Journal of neurophysiology

authors： Martinez-Salgado C,Benckendorff AG,Chiang LY,Wang R,Milenkovic N,Wetzel C,Hu J,Stucky CL,Parra MG,Mohandas N,Lewin GR

更新日期：2007-12-01 00:00:00

abstract：:Action-potential propagation into the axon terminals of olfactory receptor cells was measured with the use of voltage-sensitive dye imaging in the isolated spiny lobster brain. Conditioning shocks to the olfactory nerve, known to cause long-lasting suppression of olfactory lobe neurons, allowed the selective imaging o...

journal_title：Journal of neurophysiology

authors： Wachowiak M,Cohen LB

更新日期：1998-08-01 00:00:00

abstract：:1. Spatiotemporal receptive fields (RFs) for left and right eyes were studied for simple cells in the cat's striate cortex to examine the idea that stereoscopic depth information is encoded via structural differences of RFs between the two eyes. Traditional models are based on neurons that possess matched RF profiles ...

journal_title：Journal of neurophysiology

authors： Ohzawa I,DeAngelis GC,Freeman RD

更新日期：1996-05-01 00:00:00

abstract：:A large body of data suggests that the pontine respiratory group (PRG) is involved in respiratory phase-switching and the reconfiguration of the brain stem respiratory network. However, connectivity between the PRG and ventral respiratory column (VRC) in computational models has been largely ad hoc. We developed a net...

journal_title：Journal of neurophysiology

authors： Rybak IA,O'Connor R,Ross A,Shevtsova NA,Nuding SC,Segers LS,Shannon R,Dick TE,Dunin-Barkowski WL,Orem JM,Solomon IC,Morris KF,Lindsey BG

更新日期：2008-10-01 00:00:00

abstract：:1. We studied the effect of temporarily inhibiting neurons in the caudal fastigial nucleus in two rhesus macaques trained to make saccades to jumping targets. We placed injections of the gamma-aminobutyric acid (GABA) agonist muscimol unilaterally or bilaterally at sites in the caudal fastigial nucleus where we had re...

journal_title：Journal of neurophysiology

authors： Robinson FR,Straube A,Fuchs AF

更新日期：1993-11-01 00:00:00

abstract：:This study investigated the organization of the dorsal lateral geniculate nucleus (LGN) of the tree shrew (Tupaia glis) using both microelectrode recording and anatomical techniques. The tree shrew LGN contains approximately 100,000 cells, of which 20% are in layers 2 and 6. These two layers receive input from the ips...

journal_title：Journal of neurophysiology

authors： Conway JL,Schiller PH

更新日期：1983-12-01 00:00:00

abstract：:Unitary pallido-nigral synaptic currents were measured using optogenetic stimulation, which activated up to three unitary synaptic inputs to each substantia nigra pars reticulata (SNr) cell. Episodic barrages of synaptic conductances were generated based on in vivo firing patterns of globus pallidus pars externa (GPe)...

journal_title：Journal of neurophysiology

authors： Simmons DV,Higgs MH,Lebby S,Wilson CJ

更新日期：2020-02-01 00:00:00

abstract：:Extracellular acidification induced by retinal horizontal cells has been hypothesized to underlie lateral feedback inhibition onto vertebrate photoreceptors. To test this hypothesis, the H(+)-sensitive fluorophore 5-hexadecanoylaminofluorescein (HAF) was used to measure changes in H(+) from horizontal cells isolated f...

journal_title：Journal of neurophysiology

authors： Jacoby J,Kreitzer MA,Alford S,Malchow RP

更新日期：2014-03-01 00:00:00

abstract：:The neurons in the intermediate layers of the monkey superior colliculus (SC) that discharge before saccadic eye movements can be divided into at least two types, burst and buildup neurons, and the differences in their characteristics are compatible with different functional contributions of the two cell types. It has...

journal_title：Journal of neurophysiology

authors： Aizawa H,Wurtz RH

更新日期：1998-04-01 00:00:00

abstract：:We have examined the role of dorsal horn cells that respond to Lissauer tract stimulation in regulating primary afferent depolarization (PAD). PAD was monitored by recording the dorsal root potential (DRP) in the roots of the lumbar cord. Recordings were made of the discharges of Lissauer tract-responsive cells, and t...

journal_title：Journal of neurophysiology

authors： Lidierth M,Wall PD

更新日期：1998-08-01 00:00:00

abstract：:In this study we attempted to identify the principles that govern the changes in neural control that occur during repeated performance of a multiarticular coordination task. Eight participants produced isometric flexion/extension and pronation/supination torques at the radiohumeral joint, either in isolation (e.g., fl...

journal_title：Journal of neurophysiology

authors： Shemmell J,Forner M,Tresilian JR,Riek S,Barry BK,Carson RG

更新日期：2005-11-01 00:00:00

abstract：:To clarify the role of cholinergic inputs to the intermediate layer of the superior colliculus (SC), we examined the effect of microinjection of nicotine into the SC on visually guided saccades in macaque monkeys. After injection of 0.4-2 microl of 1-100 mM nicotine into the SC, frequency of extremely short latency sa...

journal_title：Journal of neurophysiology

authors： Aizawa H,Kobayashi Y,Yamamoto M,Isa T

更新日期：1999-09-01 00:00:00

abstract：:1. Intracellular recordings were made from neurons of the basolateral amygdala (BLA) in in vitro slice preparations to determine long-term differences in metabotropic glutamate receptor (mGluR) agonist-induced membrane responses in control and amygdala-kindled rats. 2. (2S,3S,4S)-alpha-(carboxycyclopropyl)glycine-1 (L...

journal_title：Journal of neurophysiology

authors： Holmes KH,Keele NB,Shinnick-Gallagher P

更新日期：1996-10-01 00:00:00

abstract：:1. Here we study the variability in extracellular records of action potentials. Our work is motivated, in part, by the need to construct effective algorithms to classify single-unit waveforms from multiunit recordings. 2. We used microwire electrode pairs (stereotrodes) to record from primary somatosensory cortex of a...

journal_title：Journal of neurophysiology

authors： Fee MS,Mitra PP,Kleinfeld D

更新日期：1996-12-01 00:00:00

abstract：:Contrasting theories of visual attention have emphasized selection by spatial location, individual features, and whole objects. We used functional magnetic resonance imaging to ask whether and how attention to one feature of an object spreads to other features of the same object. Subjects viewed two spatially superimp...

journal_title：Journal of neurophysiology

authors： Ernst ZR,Boynton GM,Jazayeri M

更新日期：2013-11-01 00:00:00

abstract：:Pioneering studies demonstrated that novel degrees of freedom could be controlled individually by directly encoding the firing rate of single motor cortex neurons, without regard to each neuron's role in controlling movement of the native limb. In contrast, recent brain-computer interface work has emphasized decoding ...

journal_title：Journal of neurophysiology

authors： Law AJ,Rivlis G,Schieber MH

更新日期：2014-09-15 00:00:00

abstract：:Whereas the activation of Gαi/o-coupled receptors commonly results in postsynaptic responses that show acute desensitization, the presynaptic inhibition of transmitter release caused by many Gαi/o-coupled receptors is maintained during agonist exposure. However, an exception has been noted where GABAB receptor (GABABR...

journal_title：Journal of neurophysiology

authors： Pennock RL,Hentges ST

更新日期：2016-06-01 00:00:00

abstract：:While the cochlear implant has successfully restored hearing to many deaf patients, it cannot benefit those without a functional auditory nerve or an implantable cochlea. As an alternative, the auditory midbrain implant (AMI) has been developed and implanted into deaf patients. Consisting of a single-shank array, the ...

journal_title：Journal of neurophysiology

authors： Straka MM,Schendel D,Lim HH

更新日期：2013-08-01 00:00:00

abstract：:We studied gamma-aminobutyric acid (GABA)-mediated currents in short-term cultured dorsal unpaired median (DUM) neurons of cockroach Periplaneta americana using the whole cell patch-clamp technique in symmetrical chloride solutions. All DUM neurons voltage-clamped at -50 mV displayed inward currents (I(GABA)) when 10(...

journal_title：Journal of neurophysiology

authors： Alix P,Grolleau F,Hue B

更新日期：2002-06-01 00:00:00

abstract：:1. The question of whether active uptake limits the duration of action of the inhibitory transmitter glycine has been addressed in vivo at inhibitory synapses on the goldfish Mauthner (M) cell. The kinetics of inhibitory postsynaptic potentials and inhibitory postsynaptic currents (IPSCs) evoked antidromically and by ...

journal_title：Journal of neurophysiology

authors： Titmus MJ,Korn H,Faber DS

更新日期：1996-04-01 00:00:00