Abstract:
BACKGROUND:Patients in the neonatal intensive care unit (NICU) are at high risk for healthcare-associated infections. Variability in reported infection rates among NICUs exists, possibly related to differences in prevention strategies. A better understanding of current prevention practices may help identify prevention gaps and areas for further research. METHODS:We surveyed infection control staff in NICUs reporting to the National Healthcare Safety Network (NHSN) to assess strategies used to prevent methicillin-resistant Staphylococcus aureus (MRSA) transmission and central line-associated bloodstream infections in NICUs. RESULTS:Staff from 162 of 342 NICUs responded (response rate, 47.3%). Most (92.3%) NICUs use central line insertion and maintenance bundles, but maintenance practices varied, including agents used for antisepsis and frequency of dressing changes. Forty-two percent reported routine screening for MRSA colonization upon admission for all patients. Chlorhexidine gluconate (CHG) use for central line care for at least 1 indication (central line insertion, dressing changes, or port/cap antisepsis) was reported in 82 NICUs (51.3%). Among sixty-five NICUs responding to questions on CHG use restrictions, 46.2% reported no restrictions. CONCLUSIONS:Our survey illustrated heterogeneity of CLABSI and MRSA prevention practices and underscores the need for further research to define optimal strategies and evidence-based prevention recommendations for neonates.
journal_name
Infect Control Hosp Epidemioljournal_title
Infection control and hospital epidemiologyauthors
Hocevar SN,Lessa FC,Gallagher L,Conover C,Gorwitz R,Iwamoto Mdoi
10.1086/677636subject
Has Abstractpub_date
2014-09-01 00:00:00pages
1126-32issue
9eissn
0899-823Xissn
1559-6834journal_volume
35pub_type
杂志文章abstract::The cumulative risk of human immunodeficiency virus (HIV) infection over a healthcare career has rarely been estimated, but is more relevant to the description of an occupational hazard than the risk of seroconversion from a single exposure. We describe a model for assessing the individualized risk for HIV infection a...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646161
更新日期:1990-05-01 00:00:00
abstract:OBJECTIVE:To determine knowledge and attitudes about pertussis and pertussis vaccination among healthcare workers (HCWs). DESIGN:Self-administered, Web-based survey. SETTING:Tertiary-care academic medical center. PARTICIPANTS:Medical center employees who participated in direct patient care were recruited to complete...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/521654
更新日期:2007-11-01 00:00:00
abstract::Nine hundred sixteen cultures were obtained from homes of patients with cystic fibrosis, control homes, salad bars, and food markets, and analyzed for the presence of Pseudomonas cepacia and related bacteria. P cepacia was recovered from 5 (18%) of 27 homes, and from 20 (4%) of 509 cultures collected outside of homes....
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646999
更新日期:1995-01-01 00:00:00
abstract::Studies in the 1970s and 1980s suggested that environmental surface contamination played a negligible role in the endemic transmission of healthcare-associated infections. However, recent studies have demonstrated that several major nosocomial pathogens are shed by patients and contaminate hospital surfaces at concent...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,评审
doi:10.1086/660363
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of Centers for Disease Control and Prevention (CDC)-recommended infection control measures implemented in response to an outbreak of multidrug-resistant (MDR) tuberculosis (TB). DESIGN:Retrospective cohort studies of acquired immunodeficiency syndrome (AIDS) patients and healthcare w...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647075
更新日期:1995-03-01 00:00:00
abstract:OBJECTIVE:To determine the attributable (direct) mortality and morbidity caused by carbapenem-resistant Klebsiella pneumoniae bacteremia. DESIGN:A matched retrospective, historical cohort design, using a stepwise procedure to stringently match the best control subjects to the best case subjects. SETTING:A 1,000-bed t...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/605922
更新日期:2009-10-01 00:00:00
abstract:OBJECTIVE:To investigate whether rhinovirus infection leads to increased airborne dispersal of coagulase-negative staphylococci (CoNS). DESIGN:Prospective nonrandomized intervention trial. SETTING:Wake Forest University School of Medicine, Winston-Salem, North Carolina. PARTICIPANTS:Twelve nasal Staphylococcus aureu...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502430
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVES:To quantify specific factors believed to increase healthcare worker (HCW) risk for contaminated sharps injuries (eg, visibility, communication, and range of motion); to quantify the degree to which respirators of various designs impacted those same factors; and to assess HCW opinions about the suitability of...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647566
更新日期:1997-02-01 00:00:00
abstract:OBJECTIVE:To determine the efficacy of 2 types of antimicrobial privacy curtains in clinical settings and the costs involved in replacing standard curtains with antimicrobial curtains. DESIGN:A prospective, open-labeled, multicenter study with a follow-up duration of 6 months. SETTING:This study included 12 rooms of ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2018.315
更新日期:2018-12-18 00:00:00
abstract::More than 90% of Thai hospitals surveyed reported implementing environmental cleaning and disinfection (ECD) protocols. Hospital epidemiologist presence was associated with the existence of an ECD checklist (P=.01) and of ECD auditing (P=.001), while good and excellent hospital administrative support were associated w...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2017.171
更新日期:2017-10-01 00:00:00
abstract:OBJECTIVE:To evaluate the efficacy of detergent and friction on removal of traditional biofilm and cyclic-buildup biofilm (CBB) from polytetrafluoroethylene (PTFE) channels and to evaluate the efficacy of glutaraldehyde to kill residual bacteria after cleaning. METHODS:PTFE channels were exposed to artificial test soi...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2019.306
更新日期:2020-02-01 00:00:00
abstract::Aerobic gram-negative bacillus (AGNB) groin skin carriage was prospectively studied in ambulatory geriatric outpatients: 42 from three nursing homes and 44 from private homes. Initially, 12 (28.6%) Proteeae carriers were in the former group and 3 (6.8%) were in the latter (P = 0.01). At one year, 6 of 7 surviving nurs...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/645990
更新日期:1989-04-01 00:00:00
abstract::Among 300 advanced cancer patients with potential urinary tract infection (UTI), 19 had symptomatic UTI. Among remaining patients (n = 281), 21% had asymptomatic bacteriuria or candiduria, and 14% received inappropriate therapy for 279 antimicrobial days. Bacteriuria or candiduria predicted antimicrobial therapy. At 1...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2019.22
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVE:Develop a clinical decision support tool comprised of an electronic medical record alert and antimicrobial stewardship navigator to facilitate antimicrobial stewardship. DESIGN:We analyzed alerts targeting antimicrobial de-escalation to assess the effectiveness of the navigator as a stewardship tool. The ale...
journal_title:Infection control and hospital epidemiology
pub_type: 临床试验,杂志文章
doi:10.1086/673977
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:To evaluate the influence of matching on exposure time on estimates of attributable mortality of nosocomial bacteremia as assessed by matched cohort studies. DESIGN:Two retrospective, pairwise-matched (1:2) cohort studies. SETTING:A 54-bed intensive care unit (ICU) in a university hospital. PATIENTS:Patien...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502551
更新日期:2005-04-01 00:00:00
abstract:OBJECTIVES:Two pilot studies were conducted to produce efficacy data on an observational tool designed to assess the use of Universal Precautions (UP) in patient care settings. The instrument addresses barrier precautions, hand-washing, handling of sharps, and avoidance of unprotected mouth to mouth resuscitation. DES...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646248
更新日期:1991-10-01 00:00:00
abstract::In this prospective study, we monitored 4 epidemiologically important pathogens (EIPs): methicillin-resistane Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), Clostridium difficile, and multidrug-resistant (MDR) Acinetobacter to assess the effectiveness of 3 enhanced disinfection strategies for te...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1017/ice.2018.165
更新日期:2018-09-01 00:00:00
abstract::We describe the clinical, microbiologic, and molecular features of the first series of qacA/B-containing strains of methicillin-resistant Staphylococcus aureus from infected US patients. All qac-carrying strains were clonally diverse, and qacA strains exhibited increased tolerance to chlorhexidine as measured by minim...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/662380
更新日期:2011-11-01 00:00:00
abstract::Methodologies for evaluating the efficacy of antimicrobial agents in the bacterial flora of the hand involve variations of the "glove juice" or "sterile bag" procedures. In this study we demonstrate that the subungual flora contribute significantly to the recovery of bacteria in these procedures. Culturing hands that ...
journal_title:Infection control and hospital epidemiology
pub_type: 临床试验,杂志文章
doi:10.1086/645920
更新日期:1989-10-01 00:00:00
abstract:OBJECTIVE:The study was designed to compare the efficacies of bland soap handwash and isopropyl alcohol hand rinse in preventing transfer of aerobic gram-negative bacilli to urinary catheters via transient hand colonization acquired from direct patient contact. Glove juice recovery of gram-negative bacteria was conside...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646261
更新日期:1991-11-01 00:00:00
abstract:OBJECTIVE:To collect data about personal protective equipment (PPE) management and to provide indications for improving PPE policies in Europe. DESIGN:Descriptive, cross-sectional survey. SETTING AND PARTICIPANTS:Data were collected in 48 isolation facilities in 16 European countries nominated by National Health Auth...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/667729
更新日期:2012-10-01 00:00:00
abstract::We assessed the rate of recovery of fluoroquinolone-resistant and fluoroquinolone-susceptible Escherichia coli isolates from culture of frozen perirectal swab samples compared with the results for culture of the same specimen before freezing. Recovery rates for these 2 classes of E. coli were 91% and 83%, respectively...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/529590
更新日期:2008-04-01 00:00:00
abstract::A patient with no risk factors for malaria was hospitalized in New York City with Plasmodium falciparum infection. After investigating all potential sources of infection, we concluded the patient had been exposed to malaria while hospitalized less than 3 weeks earlier. Molecular genotyping implicated patient-to-patien...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2015.236
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVES:Describe an outbreak of surgical wound infections associated with total hip arthroplasty; identify risk factors for surgical wound infection during the pre-outbreak and outbreak periods. SETTING:A 100-bed hospital. From May 1 to September 30, 1988, 7 of 15 patients who underwent total hip arthroplasty devel...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646592
更新日期:1992-09-01 00:00:00
abstract::Intracavity ultrasound transducer handles are not routinely immersed in liquid high-level disinfectants. We show that residual bacteria, including pathogens, persist on more than 80% of handles that are not disinfected, whereas use of an automated device reduces contamination to background levels. Clinical staff shoul...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2015.12
更新日期:2015-05-01 00:00:00
abstract::We observed bacterial or fungal coinfections in COVID-19 patients admitted between March 1 and April 18, 2020 (152 of 4,267, 3.6%). Among these patients, mortality was 57%; 74% were intubated; 51% with bacteremia had central venous catheters. Time to culture positivity was 6-7 days, and 79% had received prior antibiot...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.368
更新日期:2021-01-01 00:00:00
abstract::Across 36 US pediatric oncology centers, 576 central line-associated bloodstream infections (CLABSIs) were reported over a 21-month period. Most infections occurred in those with leukemia and/or profound neutropenia. The contribution of viridans streptococci infections was striking. Study findings depict the contempor...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1086/669513
更新日期:2013-03-01 00:00:00
abstract::A series of handwashing experiments using a pigskin substrate and Serratia marcescens as the contaminant compared the residual activity of a chlorhexidine detergent handwash product alone and in combination with anionic and nonionic-based moisturizing products and surfactant systems. The anionic based moisturizing pro...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646124
更新日期:1990-02-01 00:00:00
abstract:BACKGROUND:Of the 13 US vancomycin-resistant Staphylococcus aureus (VRSA) cases, 8 were identified in southeastern Michigan, primarily in patients with chronic lower-extremity wounds. VRSA infections develop when the vanA gene from vancomycin-resistant enterococcus (VRE) transfers to S. aureus. Inc18-like plasmids in V...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/671735
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Despite contact isolation precautions for patients with methicillin-resistant Staphylococcus aureus (MRSA), MRSA infections are increasing in many countries. OBJECTIVE:To evaluate the role of a potential unrecognized reservoir of MRSA carried by patients in acute care wards, we determined the prevalence of ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502514
更新日期:2005-02-01 00:00:00