Abstract:
:Across 36 US pediatric oncology centers, 576 central line-associated bloodstream infections (CLABSIs) were reported over a 21-month period. Most infections occurred in those with leukemia and/or profound neutropenia. The contribution of viridans streptococci infections was striking. Study findings depict the contemporary epidemiology of CLABSIs in hospitalized pediatric cancer patients.
journal_name
Infect Control Hosp Epidemioljournal_title
Infection control and hospital epidemiologyauthors
Gaur AH,Bundy DG,Gao C,Werner EJ,Billett AL,Hord JD,Siegel JD,Dickens D,Winkle C,Miller MR,Children's Hospital Association Hematology-Oncology Quality Transformation Collaborative Project.doi
10.1086/669513subject
Has Abstractpub_date
2013-03-01 00:00:00pages
316-20issue
3eissn
0899-823Xissn
1559-6834journal_volume
34pub_type
杂志文章,多中心研究abstract::An organic load of 5%-10% fetal calf serum significantly reduced hypochlorite and UV radiation killing of Clostridium difficile spores, but organic material collected from hospital surfaces did not affect hypochlorite and only modestly affected UV killing of spores. Hypochlorite reduced aerobic microorganisms on uncle...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/673148
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:To elucidate behavioral determinants of handwashing among nurses. DESIGN:Statistical modeling using the Theory of Planned Behavior and relevant components to handwashing behavior by nurses that were derived from focus-group discussions and literature review. SETTING:The community and 3 tertiary care hospita...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/503335
更新日期:2006-05-01 00:00:00
abstract::A crossover trial was conducted to compare hand rub and hand scrub-brush methods for reducing bacterial loads when using propan-1-ol-60% according to European regulations. Both methods significantly reduced the bacterial load immediately after antisepsis, but only the hand rub method achieved significant bacterial loa...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.1388
更新日期:2021-01-22 00:00:00
abstract:OBJECTIVE:To describe the incidence of device-associated nosocomial infections in medical-surgical intensive care units (MS ICUs) in a university hospital in Turkey and compare it with National Nosocomial Infections Surveillance (NNIS) system rates. DESIGN:Prospective surveillance study during a period of 27 months. D...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/503344
更新日期:2006-04-01 00:00:00
abstract::OBJECTIVE Biofilm has been implicated in bacterial persistence and survival after endoscope reprocessing. In this study, we assessed the impact of different methods of reprocessing on organic residues and viable bacteria after repeated rounds of biofilm formation when each was followed by full reprocessing. METHODS AT...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2017.215
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:Viruses are more common than bacteria in patients hospitalized with community-acquired pneumonia. Little is known, however, about the frequency of respiratory viral testing and its associations with antimicrobial utilization. DESIGN:Retrospective cohort study. SETTING:The study included 179 US hospitals. P...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.1312
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:To determine the impact of the screening test, nursing workload, handwashing rates, and dependence of handwashing on risk level of patient visit on methicillin-resistant Staphylococcus aureus (MRSA) transmission among hospitalized patients. SETTING:General medical ward. METHODS:Monte Carlo simulation was us...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502589
更新日期:2005-07-01 00:00:00
abstract:OBJECTIVE:To evaluate the cost-effectiveness of a dual strategy of tuberculin skin test (TST) and QuantiFERON-TB Gold (QFT-G) for screening of latent tuberculosis infection (LTBI) in healthcare workers (HCWs) and, as a secondary objective, to study relationships between TST results, QFT-G results, and sociodemographic ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/668436
更新日期:2012-12-01 00:00:00
abstract::We evaluated vancomycin use in a hospital with endemic vancomycin-resistant enterococci and a vancomycin restriction program. Only 68% of vancomycin was prescribed appropriately. Inappropriate use was due primarily to empirical therapy. In the patients with a microbiological diagnosis following empirical therapy, 83% ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/501548
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:The study was designed to compare the efficacies of bland soap handwash and isopropyl alcohol hand rinse in preventing transfer of aerobic gram-negative bacilli to urinary catheters via transient hand colonization acquired from direct patient contact. Glove juice recovery of gram-negative bacteria was conside...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646261
更新日期:1991-11-01 00:00:00
abstract:BACKGROUND:Pathogens can survive for extended periods when incorporated into biofilm on dry hospital surfaces (ie, dry-surface biofilm, DSB). Bacteria within biofilm are protected from desiccation and have increased tolerance to cleaning agents and disinfectants. OBJECTIVE:We hypothesized that gloved hands of healthca...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2018.285
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:To confirm the vertical transmission of Citrobacter diversus from a mother to her infant and to evaluate the epidemiologic usefulness of a new automated procedure for analysis of polymerase chain reaction (PCR)-generated DNA fingerprints. DESIGN:Repetitive element-based PCR (rep-PCR) analysis of C diversus i...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647009
更新日期:1995-10-01 00:00:00
abstract::We created a 2013 combination antibiogram of healthcare-associated urinary tract infection. The 2013 antibiogram-determined regimen was evaluated in a 2014 cohort who had received empirical therapy. The regimen was statistically more likely to represent adequate treatment than actual prescriptions. A customized antibi...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2016.108
更新日期:2016-09-01 00:00:00
abstract:OBJECTIVE:To determine whether empiric isolation of patients with acute respiratory virus infection symptoms could be discontinued when preliminary shell vial cultures were negative, and the impact of this approach on hospital resources. DESIGN:In 1993, we retrospectively reviewed respiratory virus test results from 1...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647389
更新日期:1996-09-01 00:00:00
abstract::We analyzed antibiotic use data from 29 southeastern US hospitals over a 5-year period to determine changes in antibiotic use after the fluoroquinolone US Food and Drug Administration (FDA) advisory update in 2016. Fluoroquinolone use declined both before and after the FDA announcement, and the use of select, alternat...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2019.247
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVE:To identify environmentally safe, rapidly acting agents for killing spores of Clostridium difficile in the hospital environment. DESIGN:Three classic disinfectants (2% glutaraldehyde, 1.6% peracetyl ions, and 70% isopropanol) and acidified nitrite were compared for activity against C. difficile spores. Four ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502129
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Fluoroquinolones have not been frequently implicated as a cause of Clostridium difficile outbreaks. Nosocomial C. difficile infections increased from 2.7 to 6.8 cases per 1000 discharges (P < .001). During the first 2 years of the outbreak, there were 253 nosocomial C. difficile infections; of ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/502539
更新日期:2005-03-01 00:00:00
abstract::Hospital antibiotic use in Argentina has not been described. We present results of point prevalence surveys on antibiotic use conducted in 109 Argentinian hospitals in November 2018 and submitted to the National Program of Epidemiology and Control of Hospital-Acquired Infections, and we discuss potential areas for imp...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2019.243
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:To determine the predictors of 7-day mortality in older adult patients with Staphylococcus aureus bacteremia after controlling for comorbidity using the Charlson weighted index of comorbidity (WIC) and to identify the risk factors associated with bacteremia due to methicillin-resistant S. aureus (MRSA). DES...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/507924
更新日期:2006-11-01 00:00:00
abstract:OBJECTIVE:To investigate an outbreak in neonates of Enterobacter cloacae infection resistant to third-generation cephalosporins. DESIGN:A retrospective study of an outbreak in the neonatal intensive care unit (NICU) and review of E cloacae isolates in pediatric wards and other intensive care units from June 1992 throu...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646998
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the effectiveness of a positive deviance strategy for the improvement of hand hygiene compliance in 2 adult step-down units. DESIGN:A 9-month, controlled trial comparing the effect of positive deviance on compliance with hand hygiene. SETTING:Two 20-bed step-down units at a tertiary care private...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/649224
更新日期:2010-01-01 00:00:00
abstract:OBJECTIVE:Antibiotic time-outs (ATOs) have been advocated to improve antibiotic use without dedicated stewardship resources, but their utility is poorly defined. We sought to evaluate the effectiveness of an ATO led by a team-based pharmacist. DESIGN:Cluster randomized controlled trial. SETTING:Six medicine teams at ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2020.347
更新日期:2020-11-01 00:00:00
abstract::The in vitro activities of bacitracin and mupirocin were compared for seven different strains of methicillin-resistant Staphylococcus aureus. Six of seven strains showed bacitracin minimum inhibitory concentrations (MICs) of 0.5 to 1.0 units/mL, and all seven had mupirocin MICs of 0.5 to 2 micrograms/mL. Time-kill stu...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/647270
更新日期:1996-03-01 00:00:00
abstract::A point prevalence survey was conducted on May 11, 2017, among inpatients at 6 hospitals in Saudi Arabia. The overall point prevalence was 6.8% (114 of 1,666). The most common types of infections were pneumonia (27.2%), urinary tract infections (20.2%), and bloodstream infections (10.5%). Approximately 19.2% of health...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1017/ice.2018.338
更新日期:2019-03-01 00:00:00
abstract::Three different sequentially applied post-varicella zoster virus (VZV) exposure management strategies were employed over a 43-month period. We began by using a standard post-exposure protocol in which 50 susceptible healthcare workers (HCW) involved in hospital exposures were furloughed from work at a loss to the hosp...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/646176
更新日期:1990-06-01 00:00:00
abstract:OBJECTIVE:To study the molecular epidemiology of vancomycin-resistant Enterococcus (VRE) colonization and to identify modifiable risk factors among patients with hematologic malignancies. SETTING:A hematology-oncology unit with high prevalence of VRE colonization. PARTICIPANTS:Patients with hematologic malignancies a...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/659408
更新日期:2011-05-01 00:00:00
abstract::We investigated a cluster of methicillin-resistant Staphylococcus aureus infections in college football players. Risk factors included a history of recurrent skin infections and contact with the skin lesions of persons outside college. The infections were controlled through treatment of carriers with topical mupirocin...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/587971
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVE:To investigate relationships between rates of antimicrobial consumption and the incidence of antimicrobial resistance in Staphylococcus aureus and Pseudomonas aeruginosa isolates from hospitals. METHODS:We conducted an observational study that used retrospective data from 2002 and linear regression to model ...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章,多中心研究
doi:10.1086/523280
更新日期:2007-12-01 00:00:00
abstract:OBJECTIVE:To determine whether methodological differences explain divergent results in case-control studies examining surgery as a risk factor for Creutzfeldt-Jakob disease (CJD). METHODS:After case-control studies were systematically identified using PubMed, we performed a homogeneity analysis and applied models to e...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/527514
更新日期:2008-03-01 00:00:00
abstract:OBJECTIVE:To investigate the potential role of blood pressure (BP) cuffs in the spread of bacterial infections in hospitals. DESIGN:A comprehensive, prospective study quantitatively and qualitatively evaluating the bacterial contamination on BP cuffs of 203 sphygmomanometers in use in 18 hospital units from January th...
journal_title:Infection control and hospital epidemiology
pub_type: 杂志文章
doi:10.1086/507284
更新日期:2006-09-01 00:00:00