Histoautoradiographic detection of DNA repair synthesis in mouse liver following dimethylnitrosamine treatment using whole-body application of labeled thymidine.

abstract：UNLABELLED:Results of radiochemotherapy in 50 patients with squamous cell carcinoma of the anal canal, treated with radical radiochemotherapy between January 2003 and September 2007, at the Institute of Oncology Ljubljana are presented. The treatment schedule consisted of 3-D conformal external beam radiotherapy (45 Gy...

journal_title：Neoplasma

authors： Oblak I,Petric P,Anderluh F,Velenik V,Hudej R,Fras AP

更新日期：2009-01-01 00:00:00

abstract：UNLABELLED:Expression patterns of proteins involved in serine and glycine metabolism, and correlations of these patterns with clinicopathologic factors in phyllodes tumor were investigated. Tissue microarrays were prepared from 203 phyllodes tumors (PT) and stained with antibodies specific for glycine decarboxylase (GL...

journal_title：Neoplasma

authors： Kwon JE,Kim DH,Jung WH,Koo JS

更新日期：2014-01-01 00:00:00

abstract：:Analysis of new primary tumors following nonmelanoma skin cancers (NMSC) has a public health and risk assessment interest, as well as potential implications for etiologic inference. The aim of this study is to evaluate the risk of the second primary tumors occurrence after NMSC development. A cohort of 2620 cases (133...

journal_title：Neoplasma

authors： Troyanova P,Danon S,Ivanova T

更新日期：2002-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most common malignancies over the world. Alpha-fetoprotein (AFP) is an oncofetal protein during HCC development, which could generate weaker and less reproducible antitumor protection, and may serve as a target for immunotherapy. Therefore, it is imperative to enhance its i...

journal_title：Neoplasma

authors： Li Z,Wang XP,Lin HP,Xu B,Zhao Q,Qi BN,Yang YX,Wang ZR

更新日期：2015-01-01 00:00:00

abstract：:Few studies to date have reported on the development and application of a nanobiosensor based on localized surface plasmon resonance (LSPR) for detecting gene mutations. This study aimed to develop a novel LSPR biosensor used for detecting p53 mutation. Nanosphere lithography was used to fabricate the silver nanoparti...

journal_title：Neoplasma

authors： Duan RQ,Yuan JL,Yang H,Luo XG,Xi MR

更新日期：2012-01-01 00:00:00

abstract：:The work is aimed at the occurrence of secondary malignancies after therapy for primary testicular tumors. The target of the work was determination of the number and type of secondary tumors, their effect on the survival and comparison of relative risk of the origination of secondary tumors depending on particular tre...

journal_title：Neoplasma

authors： Siffnerova H,Kralova D

更新日期：2007-01-01 00:00:00

abstract：:Hepatocellular carcinoma is the most common primary malignancy of the liver. The chemotherapeutic drug cisplatin is widely used for advanced liver cancer. However, the development of cisplatin resistance in cancer cells, which is related with the decreased cellular susceptibility to apoptosis, results in a major limit...

journal_title：Neoplasma

authors： Zhang B,Cao K,Liu Z,Shan W,Wen Q,Wang R

更新日期：2019-05-11 00:00:00

abstract：:The aim is to present the technical feasibility and efficacy of multiple re-irradiation (re-EBRT) for local recurrence of prostate cancer (PCa) using retrospective analysis of an updated series of patients who received ablative re-EBRT with stereotactic image-guided technique for isolated local recurrence of PCa. Eigh...

journal_title：Neoplasma

authors： Volpe S,Jereczek-Fossa BA,Zerini D,Rojas DP,Fodor C,Vavassori A,Romanelli P,Vigorito S,Rondi E,Comi S,Cambria R,Cattani F,Dicuonzo S,De Marco P,Beltramo G,Musi G,De Cobelli O,Marvaso G,Orecchia R

更新日期：2019-03-05 00:00:00

abstract：:The distribution study of zinc phthalocyanine disulfonate (ZnPcS2) in nude mice bearing mammary carcinoma (T50/80) revealed a rapid uptake of the dye by tumor. In experimental photodynamic therapy (PDT), the tumors were exposed to laser radiation (670 nm, 100 mW/cm2, 150 J/ /cm2) after intravenous administration of Zn...

journal_title：Neoplasma

authors： Mosa M,Zitko M,Poucková P

更新日期：1997-01-01 00:00:00

abstract：:Bladder cancer remains a very challenging disease to treat with the high rates of recurrence and progression associated with current therapies. Although the association between bladder cancer pathology and circRNAs remains undetermined, circRNAs signatures may be useful as prognostic and predictive factors and clinica...

journal_title：Neoplasma

authors： Liu L,Wu SQ,Zhu X,Xu R,Ai K,Zhang L,Zhao XK

更新日期：2019-06-03 00:00:00

abstract：:Authors evaluated the prevalence of symptoms of the metabolic syndrome and insulin resistance in 25 patients with adrenal incidentalomas (10 men, 15 women) of the mean age 57.9+/-15 years. 15 patients had adrenal adenoma determined by CT or MR scan and 10 had unilateral or bilateral hyperplasia. The prevalence of obes...

journal_title：Neoplasma

authors： Lazúrová I,Dudásová D,Wagnerová H,Dravecká I,Petrásová D

更新日期：2006-01-01 00:00:00

abstract：:In vivo immunogenicity and in vitro species-specific membrane antigens in tumor cells treated or untreated with glutaraldehyde (GA) were studied. Two different syngeneic Syrian hamster transplantable tumor cell lines (spontaneous liver cancer and SV40-induced sarcoma) not only lost immunogenicity after GA treatment bu...

journal_title：Neoplasma

authors： Kluchareva TE,Matveeva VA,Deichman GI

更新日期：1978-01-01 00:00:00

abstract：:The incidence of malignant tumors in children is not as high as that in adults, though in Cuba and other countries they are the most frequent causes of death in this age group. Data of the fourth triennial of the Registro Nacional del Cáncer (Cuban Cancer Registry) in the period 1973-1975 are presented. In the age gro...

journal_title：Neoplasma

authors： Alert J,Jimenez J

更新日期：1980-01-01 00:00:00

abstract：:The purpose of the present paper was to demonstrate the antitumor activity of lymphocytes and antibodies in the antibody-dependent cell-mediated cytotoxicity test (ADCC) in relation to the tumor growth in adult and aging rats bearing a methylcholanthrene-induced sarcoma (MC-Sa). In the syngeneic system using the ADCC ...

journal_title：Neoplasma

authors： Nowak JJ,Ziółkowska M,Ryzewska A

更新日期：1987-01-01 00:00:00

abstract：:The cytostatic activity of 2-thio-4-hydrazinouracil (THU) on some transplantable tumors has been studied. A strong effect of this compound (between 60% and 100% suppression) has been found in the case of Myeloma P-8 (MOPC-21) and Sarcoma 180 (Crocker). A less pronounced effect has been observed on Yoshida sarcoma, whi...

journal_title：Neoplasma

authors： Golovinsky EV,Emanuilov EA,Spassovska NC,Spassov AV

更新日期：1975-01-01 00:00:00

abstract：:The plasminogen activator (PA) production and the capacity to inhibit embryonic neural retina (NR) cell aggregation by human normal and neoplastic cell lines have been studied. The PA production was detected by both iodinated fibrin and casein lysis assays, and by changes in cell morphology at the presence of activate...

journal_title：Neoplasma

authors： Phan Thu A,Popovic M

更新日期：1979-01-01 00:00:00

abstract：:A capture monoclonal antibody-based assay has been established for detecting the p24 core protein and the gp51 envelope glycoprotein of bovine leukemia virus (BLV). This assay is rapid, highly sensitive and specific. Viral antigens in test samples were identified using mouse monoclonal antibody-coated or microtiter pl...

journal_title：Neoplasma

authors： Bán J,Altanerová V,Orlík O,Altaner C

更新日期：1991-01-01 00:00:00

abstract：:Cysteine proteinases cathepsin (Cath) B and L and their endogenous inhibitors stefin (Stef) A and B concentrations were measured using a quantitative immunosorbent assay (ELISA; KRKA d.d., Novo mesto, Slovenia) in serum samples from 35 patients with primary and 7 patients with recurrent squamous cell carcinoma of the ...

journal_title：Neoplasma

authors： Strojan P,Budihna M,Smid L,Svetic B,Vrhovec I,Skrk J

更新日期：2001-01-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a rare malignancy in the Czech Republic and Slovakia, with the standardized incidence rate of < 1:100000 person-years. Viral status of NPC in these non-endemic Eastern European regions is currently unknown. In a retrospective study, we evaluated the presence of EBV and HPV in 62 NPC c...

journal_title：Neoplasma

authors： Svajdler M Jr,Kaspirkova J,Mezencev R,Laco J,Torday T,Dubinsky P,Straka L,Ondic O,Michal M,Skalova A

更新日期：2016-01-01 00:00:00

abstract：:Von Hippel-Lindau (VHL) disease is an autosomal dominantly inherited cancer predisposition syndrome due to germline mutations in the VHL tumor suppressor gene which is associated with virtually complete penetrance. The VHL syndrome has a highly variable phenotypic expressivity including retinal and CNS haemangioblasto...

journal_title：Neoplasma

authors： Stanojevic BR,Lohse P,Neskovic GG,Damjanovic SM,Novkovic TB,Jovanovic-Cupic SP,Dimitrijević BB

更新日期：2007-01-01 00:00:00

abstract：:Twenty eight patients with germ cell testicular cancer pulmonary metastases received primary chemotherapy including bleomycin, etoposide, and cisplatin (BEP). Complete response was achieved in 21 (75%) patients, in 11 of them CR was achieved following chemotherapy alone. Postchemotherapy surgery of residual mass was p...

journal_title：Neoplasma

authors： Schnorrer M,Ondrus D,Cársky S,Hornák M,Belan V,Kausitz J,Matośka J

更新日期：1996-01-01 00:00:00

abstract：:Electronic portal imaging (EPI) is commonly used to identify and correct for inter-fraction variability in tangential breast irradiation. Based on the institutional policy, EPI registration is performed by either radiation oncologist or therapist. Little data is available on the inter-observer agreement in EPI registr...

journal_title：Neoplasma

authors： Jereczek-Fossa BA,Santoro L,Colangione SP,Morselli L,Fodor C,Vischioni B,Rozza D,Leppa A,Cambria R,Leonardi MC,Morra A,Baroni G,Zurrida S,Orecchia R

更新日期：2013-01-01 00:00:00

abstract：:This study aimed to investigate the effects of RhoGDIα knockdown on apoptosis and the chemosensitivity of lung cancer cells to paclitaxel. The signaling proteins involved were also assessed. RhoGDIα expression was assessed by RT-PCR, Western blotting and immunohistochemistry. Apoptosis was determined by flow cytometri...

journal_title：Neoplasma

authors： Rong F,Li W,Chen K,Li DM,Duan WM,Feng YZ,Li F,Zhou XW,Fan SJ,Liu Y,Tao M

更新日期：2012-01-01 00:00:00

abstract：:MiR-34a acts as a tumor suppressor in various malignancies. In HNSCC, the role of miR-34a in proliferation has not been fully elaborated and the target genes are still bind. Here, we addressed that forced miR-34a expression induced cell cycle arrest and senescence. Hypoxia/HIF1α was found to negatively correlate to th...

journal_title：Neoplasma

authors： Wang Y,Chen J,Chen X,Jiang F,Sun Y,Pan Y,Zhang W,Zhang J

更新日期：2017-01-01 00:00:00

abstract：:It is generally believed that the existence of cancer stem cells (CSCs) is related to tumor recurrence and metastasis of hepatocellular carcinoma (HCC). Neuropilin1 (NRP1) is involved in numerous pathophysiological processes of tumor progression, however, whether NRP1 is involved in the regulation of liver CSCs and me...

journal_title：Neoplasma

authors： Li X,Zhou Y,Hu J,Bai Z,Meng W,Zhang L,Song X,Wei Y,Yan J,Zhou Y

更新日期：2020-12-23 00:00:00

abstract：:The associations of several clinical factors with general survival, percentage of relapse and survival in the group of patients who relapsed were analyzed in a series of 399 Stage II breast cancer patients operated and irradiated at the Institute of Oncology and Radiobiology in Havana. In another series of 187 patient...

journal_title：Neoplasma

authors： Lage A,Rodriguez M,Pascual MR,Diaz JW,Fernandez L

更新日期：1983-01-01 00:00:00

abstract：:Cytolytic activity of mineral oil elicited rat peritoneal macrophages activated by lipopolysaccharide (LPS) and/or rIFN-gamma, rIL-2, Zymosan and PMA (4-beta-phorbol-12-beta-myristate 13-alpha-acetate) was detected in the presence of various concentrations of L-arginine. This paralleled the NO2- production in the pres...

journal_title：Neoplasma

authors： Kusenda J,Kalafut F,Klobusická M,Novotná L

更新日期：1992-01-01 00:00:00

abstract：:The treatment of locally advanced head and neck cancer (LAHNC) requires a multimodality approach. Radiotherapy with combination of chemotherapy are demonstrated to be effective, however, the treatment intensification leads to increased toxicity at the same time. The implementation of three-dimensional conformal radiot...

journal_title：Neoplasma

authors： Jirkovska M,Novak T,Malinova B,Lohynska R

更新日期：2019-06-19 00:00:00

abstract：:The aim of the study was to evaluate the influence of the receptor status of primary breast cancer and of a number of selected clinical and morphological patient characteristics. The receptors were determined by biochemical radiocompetitive methods. Disease free survival (DFS) and overall survival (OS) were determined...

journal_title：Neoplasma

authors： Skasko E,Paszko Z,Mazur S

更新日期：2005-01-01 00:00:00

abstract：:Circular RNAs (circRNAs) are a class of newly-identified non-coding RNA molecules. CircRNAs are conserved across different species and display specific organization, sequence, and expression in disease. Moreover, circRNAs' closed ring structure, insensitivity to RNase, and stability are advantages over linear RNAs in ...

journal_title：Neoplasma

authors： Zheng XB,Zhang M,Xu MQ

更新日期：2017-01-01 00:00:00