Factors associated with prognosis in human breast cancer. I. Predictors for rate of evolution and relapse.

abstract：:Circular RNAs (circRNAs) are a class of newly-identified non-coding RNA molecules. CircRNAs are conserved across different species and display specific organization, sequence, and expression in disease. Moreover, circRNAs' closed ring structure, insensitivity to RNase, and stability are advantages over linear RNAs in ...

journal_title：Neoplasma

authors： Zheng XB,Zhang M,Xu MQ

更新日期：2017-01-01 00:00:00

abstract：:We report in this study that microRNA-584-3p (miR-584-3p) is related to the vasculogenic mimicry (VM) of human glioma cells. Unsurprisingly, the postoperative survival time was significantly prolonged in those glioma patients without VM phenomena compared with those with positive VM. miR-584-3p may function as a poten...

journal_title：Neoplasma

authors： Xu S,Zhang J,Xue H,Guo X,Han X,Li T,Guo X,Gao X,Liu Q,Li G

更新日期：2017-01-01 00:00:00

abstract：:A capture monoclonal antibody-based assay has been established for detecting the p24 core protein and the gp51 envelope glycoprotein of bovine leukemia virus (BLV). This assay is rapid, highly sensitive and specific. Viral antigens in test samples were identified using mouse monoclonal antibody-coated or microtiter pl...

journal_title：Neoplasma

authors： Bán J,Altanerová V,Orlík O,Altaner C

更新日期：1991-01-01 00:00:00

abstract：:Serial cytogenetic characteristics of four lymphoblastoid cell lines derived from the peripheral blood of four patients with acute leukemia are presented, including G and C banding techniques and the analysis of sister chromatid exchanges by means of FPG technique. One of these lines turned into predominantly diploid ...

journal_title：Neoplasma

authors： Michalová K,Málková J,Cinátl J,Placerová J

更新日期：1977-01-01 00:00:00

abstract：:HCC is one of the leading causes of death worldwide. Liver transplantation including living donor transplantation is the best available treatment. We have analyzed our experience with LDLT in patients with HCC and HCV in order to determine if alpha feto-protein (AFP) is a better predictor of recurrence than the tumor ...

journal_title：Neoplasma

authors： Komorowski AL,Hsu CC,Julka KD,Vasavada B,Lin CC,Wang CC,Chen CL

更新日期：2018-03-14 00:00:00

abstract：:The effect of heterologous antimacrophage serum (AMS) and normal rabbit serum (NRS) on the immune reaction against Rous virus-induced sarcoma (RSL) was studied in rats. The growth of RSL sarcoma transplanted against the H-1 barrier in AMS-treated rats was more progressive than in the untreated or NRS-treated control g...

journal_title：Neoplasma

authors： Holán V,Chutná J,Hasek M

更新日期：1977-01-01 00:00:00

abstract：:Hippurate had antitumor effects both in vitro and in vivo by killing dose-dependently the cells derived from Skalsky lymphoma, Németh-Kellner lymphoma, L-asparaginase sensitive 6C3HED Gardner lymphoma, and LP-2 plasmacytoma. There was no significant difference between the effect of hippurate and its maternal compound ...

journal_title：Neoplasma

authors： Spustová V,Oravec C

更新日期：1989-01-01 00:00:00

abstract：:The possible association between cigarette smoking and the risk of benign breast disease (BBD) was assessed in a case-control study conducted in Gdańsk, Poland, between 1990 and 1994. The study compared 160 women with newly diagnosed BBD admitted to the Gdańsk Cancer Outpatients Clinic and 160 controls, women from out...

journal_title：Neoplasma

authors： Dziewulska-Bokiniec A

更新日期：1995-01-01 00:00:00

abstract：:Forty-four cases of well documented progressive radiation myelopathy of thoracic spinal cord were analyzed in terms of the new DFT conception (Dose-Fraction-Time). The DFT conception is a new radiobiological cell tissue kinetic model comprising explicitly repopulation. The conception has been previously tested against...

journal_title：Neoplasma

authors： Vodvárka P,Kozubek S

更新日期：1986-01-01 00:00:00

abstract：:Occurrence of uveal metastases is higher, than the number of clinically diagnosed cases, furthermore all cases are not amenable to therapy. Treatment of primary cancer is permanently improving, as a result life prospective is better, with an increasing number of late distant metastases in an unusual location, as e.g. ...

journal_title：Neoplasma

authors： Bajcsay A,Kontra G,Récsán Z,Tóth J,Fodor J

更新日期：2003-01-01 00:00:00

abstract：:Increasing evidences have proved that circular RNAs (circRNAs), identified as a specific kind of non-coding RNAs, play a potential critical role in tumorigenesis including prostate cancer. However, the function of circRNAs in human prostate cancer remain largely unknown. In this study, we demonstrated that the express...

journal_title：Neoplasma

authors： Jiang H,Lv DJ,Song XL,Wang C,Yu YZ,Zhao SC

更新日期：2020-01-01 00:00:00

abstract：:Cisplatin-based chemotherapy is highly effective in advanced seminoma, but at the cost of a considerable toxicity. The response rate of carboplatin is comparable with cisplatin combinations but the relapse rate is higher. Our study assesses the efficacy and the toxicity of the combination of carboplatin and cyclophosp...

journal_title：Neoplasma

authors： Mardiak J,Sálek T,Sycova-Milá Z,Sufliarsky J,Baláz M,Koza I

更新日期：2000-01-01 00:00:00

abstract：:Sixty-five patients with Stage I and II endometrial carcinoma were investigated. After a short-time follow-up (17-24 months) significant differences in frequency of relapses were observed between patients with tumors containing low amounts of estrogen receptor (ER less than 60 fmol/mg DNA) in the nuclear pellet, and t...

journal_title：Neoplasma

authors： Horvath G,Johnsson JE,Tropé C,Samuelsson L,Alm P,Olsson H

更新日期：1990-01-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a rare malignancy in the Czech Republic and Slovakia, with the standardized incidence rate of < 1:100000 person-years. Viral status of NPC in these non-endemic Eastern European regions is currently unknown. In a retrospective study, we evaluated the presence of EBV and HPV in 62 NPC c...

journal_title：Neoplasma

authors： Svajdler M Jr,Kaspirkova J,Mezencev R,Laco J,Torday T,Dubinsky P,Straka L,Ondic O,Michal M,Skalova A

更新日期：2016-01-01 00:00:00

abstract：:Implantation of the RL-67 tumor in to the limb muscle of C57Bl strain mice resulted in the tumor growth at the site of implantation and the metastatic process became manifest predominantly in the lungs of all animals. A direct correlation was established between the primary tumor and its metastases. The number of meta...

journal_title：Neoplasma

authors： Karaivanova M,Getov H

更新日期：1978-01-01 00:00:00

abstract：:Hepatocellular carcinoma is the most common primary malignancy of the liver. The chemotherapeutic drug cisplatin is widely used for advanced liver cancer. However, the development of cisplatin resistance in cancer cells, which is related with the decreased cellular susceptibility to apoptosis, results in a major limit...

journal_title：Neoplasma

authors： Zhang B,Cao K,Liu Z,Shan W,Wen Q,Wang R

更新日期：2019-05-11 00:00:00

abstract：:Comparative studies on the presence and immunological reactivity of CEA and CEA-like antigens in lung and digestive tract cancers were performed. Specific goat and rabbit anti-CEA immune sera were used. Immunofluorescence studies revealed in histologically different types of the lung carcinomas the presence of the cro...

journal_title：Neoplasma

authors： Harłozińska A,Albert W,Rogalski E,Richter R,Albert Z

更新日期：1979-01-01 00:00:00

abstract：:In this work we tried to estimate the role of mitochondria in the ability of cells of two: melanotic and amelanotic transplantable melanoma lines to undergo spontaneous and camptothecin-induced apoptosis. We measured mitochondrial transmembrane potential (DeltaPsi) changes during culture without (spontaneous apoptosis...

journal_title：Neoplasma

authors： Cichorek M,Kozłowska K,Bryl E

更新日期：2007-01-01 00:00:00

abstract：:The development of distant metastases is the final stage in the progression of solid cancer and is responsible for the majority of cancer-related deaths. Epithelial-mesenchymal transition (EMT) is involved in cancer progression and metastasis. In the present study we used different types of intracellular bacteria isol...

journal_title：Neoplasma

authors： Wachsmannova L,Stevurkova V,Ciernikova S

更新日期：2019-02-06 00:00:00

abstract：:MSH-PE38KDEL is a chimeric molecule composed of MSH, and fused to a truncated mutant form of Pseudomonas exotoxin (PE38KDEL). Our study aims to evaluate the specific cytotoxicity of recombinant immunotoxin MSH-PE38KDEL on melanoma cells A875 and B16 in vitro, as well as its inhibition of metastatic melanoma in vivo. M...

journal_title：Neoplasma

authors： Hui Q,Ma J,Song J,Liu Z,Ren H,Jiang W,Wang Y,Xu Y,Guo D,Zhang X,Lu S

更新日期：2014-01-01 00:00:00

abstract：UNLABELLED:Oncolytic viruses are examined to serve as anticancer therapeutics. It is expected that in addition to direct oncolytic effect their action will also help eliciting a solid antitumor immunity. In presented series of experiments we have employed two HPV16-transformed mouse (strain C57/B6) cell lines, TC-1 and...

journal_title：Neoplasma

authors： Figova K,Sobotkova E,Duskova M,Ludvikova V,Vonka V,Eckschlager T

更新日期：2010-01-01 00:00:00

abstract：:High-dose chemotherapy (HDC) in high-risk breast cancer is one of the possible approaches how to improve therapeutic results, eventually, to overcome the incurability of the disease. In recent randomized studies superiority of HDC to conventional therapy has not been unambiguously established. Nevertheless, many oncol...

journal_title：Neoplasma

authors： Filip S,Petera J,Odrázka K,Bláha M

更新日期：2000-01-01 00:00:00

abstract：:This study was supposed to investigate the correlation between the functional single nucleotide polymorphisms (SNPs) (rs2516839 and rs3737787) in USF1 gene and the efficacy and safety of paclitaxel-based chemotherapy and prognosis in the treatment of ovarian cancer (OC). In total 100 OC patients were selected and divi...

journal_title：Neoplasma

authors： Ye H,Liu XJ,Hui Y,Liang YH,Li CH,Wan Q

更新日期：2018-01-01 00:00:00

abstract：:CD147, a widely expressed cell surface glycoprotein in cancer, is associated with tumor invasiveness and chemotherapy resistance. Recently, CD147 is also regarded as a potential therapeutic target for cancer therapy. The aim of the study was to investigate CD147 expression in non-small cell lung cancer (NSCLC), and ev...

journal_title：Neoplasma

authors： Zeng HZ,Qu YQ,Liang AB,Deng AM,Zhang WJ,Xiu B,Wang H,Wang H

更新日期：2011-01-01 00:00:00

abstract：:Mouse lymphosarcoma LS/BL cells growing in tissue culture were irradiated with 100, 316 and 1000 R respectively and fixed 5, 15 or 60 minutes later. Semithin sections were studied under a light and ultrathin under an electron microscopes. Under the light microscope, differences between the morphology of individual nuc...

journal_title：Neoplasma

authors： Tkadlecek L,Karpfel Z,Cibulka M,Viklická S,Spurná V

更新日期：1975-01-01 00:00:00

abstract：:Overexpressed Wilms tumor gene 1 (WT1) has been found in a majority of patients with acute myeloid leukemia (AML). The aim of this study was to confirm the applicability of WT1 expression measurement as a marker of minimal residual disease (MRD). The expression of WT1 gene was measured by real-time polymerase chain re...

journal_title：Neoplasma

authors： Polak J,Hajkova H,Haskovec C,Cechova H,Marinov I,Mikulenkova D,Markova J,Markova M,Vitek A,Valkova V

更新日期：2013-01-01 00:00:00

abstract：:The analysis of DNA methylation patterns in circulating cell-free DNA in body fluids is an analyte of great interest in clinical research. Downstream of Kinase (DOK) proteins represent a multigenic family of adaptors that includes negative regulators of immune cell signaling and plays important roles in signaling, cel...

journal_title：Neoplasma

authors： Heidarizadi A,Salimi M,Mozdarani H

更新日期：2020-07-01 00:00:00

abstract：:Using the model of Sarcoma I (SaI) (H-2a) tumor allograft transplanted to normal B10 (H-2b) mice and to B10 mice pretreated with ATS, we studied the effects of anti-Thy-1,2 monoclonal antibody (MTA) and compared them with those of rabbit polyvalent antiserum against mouse thymocytes (ATS). When administered shortly be...

journal_title：Neoplasma

authors： Sobotková E,Sůla K,Nouza K

更新日期：1988-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide, and it carries a poor prognosis. Clarifying the pathologic mechanisms of this disease will be beneficial for the diagnosis and treatment of HCC. LncRNA MEG8 is involved in several tumors but its role in HCC progression remains unknown. This st...

journal_title：Neoplasma

authors： Lou J,Yan W,Li QY,Zhu AK,Tan BQ,Dong R,Zou XZ,Liu T

更新日期：2020-11-05 00:00:00

abstract：:The efficacy of cis-platinum in the treatment of recurrent advanced malignant melanoma is discussed and also the so far unpublished clinical data have been summed up. On account of the considerable differences among these data the clinical study of Stage II had been started which should contribute to the elucidation o...

journal_title：Neoplasma

authors： Mechl Z,Krejcí P

更新日期：1983-01-01 00:00:00