Abstract：
:In vivo immunogenicity and in vitro species-specific membrane antigens in tumor cells treated or untreated with glutaraldehyde (GA) were studied. Two different syngeneic Syrian hamster transplantable tumor cell lines (spontaneous liver cancer and SV40-induced sarcoma) not only lost immunogenicity after GA treatment but were responsible for enhancement of test-tumor growth in immunized animals. In vitro mixed hemadsorption test used for determination of species-specific membrane antigens in Syrian hamster, green monkey and interspecies hybrid cells revealed drastic alteration of antigens on the membrane of cells treated with GA.
journal_name
Neoplasmajournal_title
Neoplasmaauthors
Kluchareva TE,Matveeva VA,Deichman GIsubject
Has Abstractpub_date
1978-01-01 00:00:00pages
273-8issue
3eissn
0028-2685issn
1338-4317journal_volume
25pub_type
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