Esophagectomy for superficial esophageal cancer after non-curative endoscopic resection.

Abstract:

BACKGROUND:Additional surgical treatment after non-curative endoscopic resection for superficial esophageal cancer should be considered unless the tumor is pathologically proven to be categorized within the absolute indication of endoscopic resection. However, the significance of this treatment strategy has been poorly evaluated until now. METHODS:Additional esophagectomy with lymph node dissection was carried out for a total of 34 patients with esophageal cancer pathologically diagnosed as in contact with or invading the muscularis mucosa (pT1a-MM) or submucosa (pSM) and/or accompanying vascular permeation after endoscopic resection. The surgical results, pathological diagnosis after esophagectomy, and outcomes were analyzed. RESULTS:The pathological diagnosis after endoscopic resection revealed pT1a-MM in 7 patients, pSM in 27 patients, and vessel permeation in 24 patients. The approach to esophagectomy was via right and left thoracotomy in 26 patients and 2 patients, respectively, and was transhiatal in 6 patients. Three-field lymph node dissection was performed in 12 patients, and the mean number of dissected lymph nodes was 72 (range 31-132). Pathological lymph node metastasis was noted in 10 patients. Postoperative complications developed in 10 patients, and death due to pulmonary complications was observed in one patient. No postoperative recurrence was observed during the follow-up period (1-87 months). CONCLUSIONS:Esophagectomy after endoscopic resection provides favorable disease control for esophageal cancer with pT1a-MM/pSM and/or vessel permeation, while strict consideration is required to determine the indication and procedure for surgery because of its invasiveness.

journal_name

J Gastroenterol

authors

Saeki H,Watanabe M,Mine S,Shigaki H,Oya S,Ishiyama A,Tsuchida T,Fujisaki J,Baba H,Maehara Y,Sano T

doi

10.1007/s00535-014-0983-6

subject

Has Abstract

pub_date

2015-04-01 00:00:00

pages

406-13

issue

4

eissn

0944-1174

issn

1435-5922

journal_volume

50

pub_type

杂志文章
  • Clinical significance of a papillary adenocarcinoma component in early gastric cancer: a single-center retrospective analysis of 628 surgically resected early gastric cancers.

    abstract:BACKGROUND:We recently reported that the presence of a papillary adenocarcinoma (pap) component was an independent risk factor for lymphatic involvement in endoscopically resected early gastric cancer (EGC). This study aimed to investigate the potential association between the presence of a pap component in EGC and lym...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-014-0991-6

    authors: Sekiguchi M,Kushima R,Oda I,Suzuki H,Taniguchi H,Sekine S,Fukagawa T,Katai H

    更新日期:2015-04-01 00:00:00

  • Incidence and clinical outcomes of intestinal Behçet's disease in Korea, 2011-2014: a nationwide population-based study.

    abstract:BACKGROUND:Intestinal Behçet's disease (BD) is very rare, and epidemiologic data regarding BD are scarce. Moreover, there have been no population-based studies focusing on intestinal BD. We conducted a nationwide population-based study to examine the incidence and clinical course of Korean patients with intestinal BD. ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-016-1300-3

    authors: Han M,Jung YS,Kim WH,Cheon JH,Park S

    更新日期:2017-08-01 00:00:00

  • Intestine-specific homeobox (ISX) induces intestinal metaplasia and cell proliferation to contribute to gastric carcinogenesis.

    abstract:BACKGROUND:Helicobacter pylori induces chronic inflammation and intestinal metaplasia (IM) through genetic and epigenetic changes and activation of intracellular signaling pathways that contribute to gastric carcinogenesis. However, the precise mechanism of IM in gastric carcinogenesis has not been fully elucidated. We...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-016-1176-2

    authors: Sue S,Shibata W,Kameta E,Sato T,Ishii Y,Kaneko H,Miwa H,Sasaki T,Tamura T,Kondo M,Maeda S

    更新日期:2016-10-01 00:00:00

  • Hepatocellular carcinoma in patients with nonalcoholic steatohepatitis.

    abstract:BACKGROUND:There have been few reports on hepatocellular carcinoma (HCC) in nonalcoholic steatohepatitis (NASH) and the natural history of NASH. Accordingly, we assessed the clinical features of HCC in NASH, the risk factors for HCC, and natural history of NASH with advanced fibrosis. PATIENTS AND METHODS:There were 3...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-008-2262-x

    authors: Hashimoto E,Yatsuji S,Tobari M,Taniai M,Torii N,Tokushige K,Shiratori K

    更新日期:2009-01-01 00:00:00

  • Meta-analysis: the effect of interferon on development of hepatocellular carcinoma in patients with chronic hepatitis B virus infection.

    abstract:PURPOSE:In patients chronically infected with hepatitis B virus, interferon has been used for the purpose of viral suppression by loss of hepatitis B e antigen (HBeAg) with or without seroconversion to antibody to HBeAg (anti-HBe). However, discussion about the effect of interferon on the development of hepatocellular ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,meta分析

    doi:10.1007/s00535-009-0024-z

    authors: Miyake Y,Kobashi H,Yamamoto K

    更新日期:2009-01-01 00:00:00

  • Current status of preoperative biliary drainage.

    abstract::Preoperative biliary drainage (PBD) has been thought to be preferable regardless of the site of biliary strictures, e.g., distal or proximal strictures because PBD by endoscopy or interventional radiology decreases postoperative mortality and morbidity rates. However, recently, several studies have revealed that PBD s...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1007/s00535-015-1096-6

    authors: Umeda J,Itoi T

    更新日期:2015-09-01 00:00:00

  • Colonic cancer in a patient with primary sclerosing cholangitis and long-standing ulcerative colitis.

    abstract::A 27-year-old woman with a 9-year history of ulcerative colitis involving the entire colon was admitted to our hospital in August 1992 because of bloody stools and left lower abdominal pain. She had been treated with sulfasalazine since 1983 and the colitis had been clinically quiescent or mild for 7 years. She had al...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/BF01213301

    authors: Seo M,Okada M,Osamura S,Hara S,Umeno T,Maeshiro K,Yamada Y,Yuh K

    更新日期:1997-02-01 00:00:00

  • Risk factors of nonadherence to colonoscopy surveillance after polypectomy and its impact on clinical outcomes: a KASID multicenter study.

    abstract:BACKGROUND:An optimal surveillance program is important to prevent advanced colorectal neoplasm. In this context, we have evaluated the cumulative risk of high-risk adenoma (HRA) or colorectal cancer (CRC) according to surveillance interval time after polypectomy. In addition, we assessed risk factors for late surveill...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s00535-016-1280-3

    authors: Tae CH,Moon CM,Kim SE,Jung SA,Eun CS,Park JJ,Seo GS,Cha JM,Park SC,Chun J,Lee HJ,Jung Y,Kim JO,Joo YE,Park DI

    更新日期:2017-07-01 00:00:00

  • Eradication of Helicobacter pylori using 30 mg or 60 mg lansoprazole combined with amoxicillin and metronidazole: one and two weeks of a new triple therapy.

    abstract::A new triple therapy using a proton pump inhibitor and two antibiotics shows high efficiency against Helicobacter pylori infection. The aim of this study was to determine the optimal dose and duration of lansoprazole (LA) administration in combination with amoxicillin (AMPC) and metronidazole (MNZ). A total of 91 pati...

    journal_title:Journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Nishikawa K,Sugiyama T,Ishizuka J,Kudo T,Komatsu Y,Katagiri M,Sukegawa M,Kagaya H,Kudo M,Kato M,Takeda H,Toyota J,Asaka M

    更新日期:1999-01-01 00:00:00

  • The long-term outcome of patients with bleeding gastric varices after balloon-occluded retrograde transvenous obliteration.

    abstract:BACKGROUND:The purpose of our study was to evaluate the long-term outcome and complications of balloon-occluded retrograde transvenous obliteration (B-RTO) in patients with hemorrhage from gastric fundal varices. METHODS:Thirty-four consecutive patients with bleeding from gastric varices who were treated with B-RTO we...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-007-2077-1

    authors: Hiraga N,Aikata H,Takaki S,Kodama H,Shirakawa H,Imamura M,Kawakami Y,Takahashi S,Toyota N,Ito K,Tanaka S,Kitamoto M,Chayama K

    更新日期:2007-08-01 00:00:00

  • Symptomatic and endoscopic outcome of heartburn 3-4.5 years after starting lansoprazole therapy: a prospective study of 142 patients.

    abstract:BACKGROUND:Heartburn is a common symptom with great impact on quality of life and on the economy. An approach that helps to alleviate patients' symptoms, decrease the burden on the economy, and improve longterm outcome is needed. Step-down therapy, starting with the proton pump inhibitor lansoprazole, seems to achieve ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-003-1194-8

    authors: Abu Farsakh N

    更新日期:2003-01-01 00:00:00

  • Endoscopic characterization of the small bowel in patients with portal hypertension evaluated by double balloon endoscopy.

    abstract:BACKGROUND:The endoscopic abnormalities present in the small bowel (SB) of patients with portal hypertension (PH) are not well understood. This study sought to evaluate endoscopic findings of the SB in patients with PH by double balloon endoscopy (DBE). METHODS:We evaluated the endoscopic findings of SB in 15 patients...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-008-2198-1

    authors: Kodama M,Uto H,Numata M,Hori T,Murayama T,Sasaki F,Tsubouchi N,Ido A,Shimoda K,Tsubouchi H

    更新日期:2008-01-01 00:00:00

  • The recovery of the PT-INR to less than 1.3 predicts survival in patients with severe acute liver injury.

    abstract:BACKGROUND:Acute liver failure is a potentially fatal disease of various etiologies for which liver transplantation is the only known curative treatment. Although the decision-making on transplantation is largely dependent on the severity of liver injury (based on predicting a fatal outcome), a statistical analysis to ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-017-1421-3

    authors: Mawatari S,Moriuchi A,Ohba F,Kawano T,Oda K,Takikawa Y,Takikawa H,Ido A,Tsubouchi H

    更新日期:2018-07-01 00:00:00

  • Microvessel density correlates with lymph node metastases and prognosis in hilar cholangiocarcinoma.

    abstract:BACKGROUND:Neovascularization was shown to be critically involved in the progression of multiple cancers, and treatment approaches targeting tumor-associated neovascularization provide convincing results in recent years in some tumor entities. However, little is known about the tumor-associated neovascularization in hi...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-008-2255-9

    authors: Thelen A,Scholz A,Benckert C,Schröder M,Weichert W,Wiedenmann B,Neuhaus P,Jonas S

    更新日期:2008-01-01 00:00:00

  • Granular cell tumor occurring in the sigmoid colon treated by endoscopic mucosal resection using a transparent cap (EMR-C).

    abstract::A case of granular cell tumor occurring in the sigmoid colon is reported. The patient, a 56-year-old man, visited our hospital for further evaluation of occult blood in his stool. Endoscopic examination revealed a yellowish, hemispheric submucosal tumor (SMT) with redness, about 6 mm in diameter, in the sigmoid colon....

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1007/s005350300068

    authors: Endo S,Hirasaki S,Doi T,Endo H,Nishina T,Moriwaki T,Nakauchi M,Masumoto T,Tanimizu M,Hyodo I

    更新日期:2003-01-01 00:00:00

  • Interferon lowers tumor recurrence rate after surgical resection or ablation of hepatocellular carcinoma: a pilot study of patients with hepatitis B virus-related cirrhosis.

    abstract:BACKGROUND:Hepatocellular carcinoma (HCC) caused by hepatitis B virus (HBV) often recurs after surgical or medical treatment. METHODS:Eighty consecutive patients with HBV-positive cirrhosis and HCC who underwent potentially curative ablation for HCC were analyzed. Eleven patients received long-term interferon (IFN) th...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-006-1912-0

    authors: Someya T,Ikeda K,Saitoh S,Kobayashi M,Hosaka T,Sezaki H,Akuta N,Suzuki F,Suzuki Y,Arase Y,Kumada H

    更新日期:2006-12-01 00:00:00

  • Aberrant methylation of p16 predicts candidates for 5-fluorouracil-based adjuvant therapy in gastric cancer patients.

    abstract:BACKGROUND:Aberrant methylation of some cancer-related genes has been reported to correlate with sensitivity to chemotherapeutic agents. The present study was designed to determine whether DNA methylation in six cancer-related genes affects recurrence of gastric cancer in patients who received 5-fluorouracil-based adju...

    journal_title:Journal of gastroenterology

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00535-007-2113-1

    authors: Mitsuno M,Kitajima Y,Ide T,Ohtaka K,Tanaka M,Satoh S,Miyazaki K

    更新日期:2007-11-01 00:00:00

  • Long-term outcome of autoimmune pancreatitis.

    abstract:PURPOSE:Autoimmune pancreatitis (AIP) is a unique form of pancreatitis and can be complicated with various extrapancreatic lesions. Little is known about the long-term clinical course of AIP. Here we aimed to document the clinical course of AIP. METHODS:For this study, we recruited 21 patients, averaging 66.5 years in...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-009-0049-3

    authors: Uchida K,Yazumi S,Nishio A,Kusuda T,Koyabu M,Fukata M,Miyoshi H,Sakaguchi Y,Fukui T,Matsushita M,Takaoka M,Okazaki K

    更新日期:2009-01-01 00:00:00

  • A patient who survived total colonic type ulcerative colitis complicated by toxic megacolon, disseminated intravascular coagulation, methicillin-resistant Staphylococcus aureus infection and bilateral femoral phlebothrombosis.

    abstract::We report a patient who survived total colonic type ulcerative colitis (UC) complicated by toxic megacolon (TM), disseminated intravascular coagulation (DIC), methicillin-resistant Staphylococcus aureus infection, and phlebothrombosis. A 69-year-old man was treated for about 4 months under the diagnosis of ischemic co...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,评审

    doi:10.1007/s005350050282

    authors: Arai H,Hanai H,Furuta T,Sato Y,Yamada M,Kaneko E,Baba S,Sugimura H

    更新日期:1999-06-01 00:00:00

  • An assessment of bisacodyl-based bowel preparation for colonoscopy in children.

    abstract:BACKGROUND:The most commonly used methods for bowel preparation are polyethylene glycol-electrolyte lavage solution (PEG-ELS) and sodium phosphate. Both are problematic in children. The use of bisacodyl together with fleet enema has been suggested as an alternative; however, its use without dietary restriction is infer...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-006-1958-z

    authors: Shaoul R,Haloon L

    更新日期:2007-01-01 00:00:00

  • Viral serostatus and coexisting inflammatory activity affect metachronous carcinogenesis after hepatectomy for hepatocellular carcinoma. A further report.

    abstract::Little data are available regarding the effects of hepatitis virus serostatus and the severity of coexisting chronic inflammation on intrahepatic recurrence after hepatectomy for hepatocellular carcinoma (HCC). We investigated the extent to which these factors modified the prognosis of hepatectomized patients. A total...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s005350050332

    authors: Yamanaka N,Takada M,Tanaka T,Yamanaka J,Yasui C,Ando T,Maeda S,Matsushita K,Okamoto E

    更新日期:2000-01-01 00:00:00

  • Chemotaxis and motility of Helicobacter pylori in a viscous environment.

    abstract::The chemotactic activity of Helicobacter pylori is important for its colonization. H. pylori exhibited chemotactic responses to urea and potassium bicarbonate, which can be supplied from human gastric epithelium. The chemotactic activities of H. pylori in a fluid environment were higher on the urease-positive strain t...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:

    authors: Yoshiyama H,Nakamura H,Kimoto M,Okita K,Nakazawa T

    更新日期:1999-01-01 00:00:00

  • Effects of transjugular intrahepatic portosystemic shunt on changes in the small bowel mucosa of cirrhotic patients with portal hypertension.

    abstract:BACKGROUND:The introduction of capsule endoscopy (CE) has facilitated the detection of mucosal changes in the small bowel, and such mucosal changes have been noted in cirrhotic patients with portal hypertension; these changes are described as portal hypertensive enteropathy. The aim of this study was to assess the effe...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-012-0660-6

    authors: Matsushita Y,Narahara Y,Fujimori S,Kanazawa H,Itokawa N,Fukuda T,Takahashi Y,Kondo C,Kidokoro H,Atsukawa M,Nakatsuka K,Sakamoto C

    更新日期:2013-05-01 00:00:00

  • Hepatic vascular side effects of styrene maleic acid neocarzinostatin in the treatment of hepatocellular carcinoma.

    abstract::Styrene-maleic acid neocarzinostatin (SMANCS) sometimes causes hepatic vascular side effects, including arterial stricture, obstruction, and arterio-portal shunt. A total of 128 intra-arterial SMANCS injection treatments, performed for 89 patients with hepatocellular carcinoma, were analyzed to determine the relations...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s005350050360

    authors: Ikeda K,Saitoh S,Kobayashi M,Suzuki Y,Suzuki F,Tsubota A,Arase Y,Chayama K,Murashima N,Kumada H

    更新日期:2000-01-01 00:00:00

  • Recent clinical features of Wilson's disease with hepatic presentation.

    abstract:BACKGROUND:We carried out this study to evaluate recent clinical features of Wilson's disease (WD) with hepatic presentation, especially in terms of age, degree of liver injury, and association with hepatocellular carcinoma (HCC). METHODS:Sixteen patients with hepatic manifestations were diagnosed with WD in the perio...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-004-1466-y

    authors: Kumagi T,Horiike N,Michitaka K,Hasebe A,Kawai K,Tokumoto Y,Nakanishi S,Furukawa S,Hiasa Y,Matsui H,Kurose K,Matsuura B,Onji M

    更新日期:2004-12-01 00:00:00

  • Inhibitory effects of n-3 polyunsaturated fatty acids on sigmoid colon cancer transformants.

    abstract::Various types of polyunsaturated fatty acids (PUFAs) have been suggested to exert different effects on the colon in terms of promotion or inhibition of tumor development. Results of in vitro and in vivo studies are, however, inconsistent and it remains unclear whether or not the cellular effects of PUFAs change along ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s005350050071

    authors: Tsai WS,Nagawa H,Kaizaki S,Tsuruo T,Muto T

    更新日期:1998-04-01 00:00:00

  • Pulmonary blood transit time and impaired arterial oxygenation in patients with chronic liver disease.

    abstract:BACKGROUND:Contrast-enhanced echocardiography (CEE) using agitated saline can detect intrapulmonary vasodilatation (IPVD) in patients with hepatopulmonary syndrome (HPS). We estimated the pulmonary transit time of erythrocytes (PTT) by CEE, using microbubbles, and studied its relationship to arterial oxygenation in chr...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-004-1495-6

    authors: Katsuta Y,Honma H,Zhang XJ,Ohsuga M,Komeichi H,Shimizu S,Katoh Y,Miura H,Satomura K,Aramaki T,Takano T

    更新日期:2005-01-01 00:00:00

  • Adding interferon to lamivudine enhances the early virologic response and reversion of the precore mutation in difficult-to-treat HBV infection.

    abstract:BACKGROUND:The virologic impact of adding interferon to antiviral nucleoside therapy was studied in Japanese patients having perinatally transmitted hepatitis B virus (HBV) genotype C. METHODS:Sixty-four patients including 41 positive for hepatitis B e antigen (HBeAg) were assigned to receive either (1) a combination ...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00535-008-2174-9

    authors: Yuki N,Nagaoka T,Nukui K,Omura M,Hikiji K,Kato M

    更新日期:2008-01-01 00:00:00

  • Management of chronic hepatitis C and prevention of hepatocellular carcinoma.

    abstract::Hepatitis C virus (HCV) infection is responsible for more than a half of the cases of chronic viral hepatitis in Japan. About 20% of patients who are chronically infected with the virus develop cirrhosis about 20-30 years after the infection, with hepatocellular carcinoma developing in about 5% of patients a year. The...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/BF02990103

    authors: Chayama K

    更新日期:2002-01-01 00:00:00

  • Long-term prognosis of patients with hepatitis B infection: causes of death and utility of nucleos(t)ide analogue therapy.

    abstract:BACKGROUND:Long-term nucleos(t)ide analogue (NA) therapy for chronic hepatitis B (CHB) patients has been reported to reduce the risk of hepatocellular carcinoma (HCC) development. However, survival rates and causes of death in CHB patients either treated or not treated with NA therapy are unclear. Therefore, we investi...

    journal_title:Journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1007/s00535-014-1011-6

    authors: Tada T,Kumada T,Toyoda H,Kiriyama S,Tanikawa M,Hisanaga Y,Kanamori A,Kitabtake S,Ito T

    更新日期:2015-07-01 00:00:00