Abstract:
:Serum ratios of monoclonal immunoglobulin (Ig) to total protein, monoclonal immunoglobulin to albumin, CSF/serum Ig-albumin index, and CSF to serum monoclonal immunoglobulin were obtained in 21 patients with multiple myeloma and 2 with Waldenström's macroglobulinemia. Twelve patients (3 with CNS complications) showed CSF monoclonal proteins similar to their serum. CSF IgA levels above 10 mg/dl, IgG levels above 25 mg/dl, CSF-serum IgG ratios above 0.0034 and CSF-serum IgA ratios above 0.0051 were seen in patients with neurologic complications. Our preliminary data may signal early CNS involvement in multiple myeloma.
journal_name
Neurologyjournal_title
Neurologyauthors
Hansotia P,Gani K,Friedenberg Wdoi
10.1212/wnl.33.11.1411subject
Has Abstractpub_date
1983-11-01 00:00:00pages
1411-5issue
11eissn
0028-3878issn
1526-632Xjournal_volume
33pub_type
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