Analysis of paternity. The use of HLA and red cell antigens.

abstract：BACKGROUND:Endothelial cells (ECs) play a pivotal role in the allogeneic immune response upon transplantation. Semaphorin 3A (Sema3A) was implicated in the modulation of EC growth, but its effects on immunogenicity were not previously investigated. STUDY DESIGN AND METHODS:ECs were transduced with a lentiviral vector ...

journal_title：Transfusion

authors： Schlahsa L,Zhang H,Battermann A,Verboom M,Immenschuh S,Eiz-Vesper B,Stripecke R,Engelmann K,Blasczyk R,Figueiredo C

更新日期：2014-08-01 00:00:00

abstract：:The transfusion of red cells (RBCs) was analyzed over a 4-year period (1984-1987), during which 9596 cesarean deliveries were performed. A total of 336 patients were identified as receiving RBC transfusions during or after cesarean delivery; 747 units of RBCs were administered. The overall incidence of transfusion in ...

journal_title：Transfusion

authors： Camann WR,Datta S

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Qualitative RHD variants are the result of the replacement of RHD exons by their RHCE counterparts or of point mutations in RHD causing amino acid substitutions. For RHD typing, the use of at least two RHD typing polymerase chain reaction (PCR) assays directed at different regions of RHD is advised to preven...

journal_title：Transfusion

authors： Maaskant-van Wijk PA,Faas BH,de Ruijter JA,Overbeeke MA,von dem Borne AE,van Rhenen DJ,van der Schoot CE

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Platelet (PLT) transfusions are essential for patients who are bleeding or have an increased risk of bleeding due to a decreased number or abnormal function of circulating PLTs. A shelf life of 5 days for PLT products presents an inventory management challenge. In 2006, greater than 10% of apheresis PLTs mad...

journal_title：Transfusion

authors： Fuller AK,Uglik KM,Braine HG,King KE

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Dendritic cells (DCs) are the most potent antigen-presenting cells that initiate and regulate immune responses. They are unique in their feature to produce bioactive interleukin (IL)-12, a major proinflammatory cytokine connecting innate and adaptive immunity. Platelets (PLTs) are highly reactive components ...

journal_title：Transfusion

authors： Kissel K,Berber S,Nockher A,Santoso S,Bein G,Hackstein H

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Routine HCV NAT of blood donors to detect persons in the preseroconversion phase of acute infection was introduced in Canada in October 1999. The source of virus exposure was investigated in the first, and to date only, blood donor found to be HCV NAT positive, anti-HCV negative in Canada. He was a regular d...

journal_title：Transfusion

authors： Larke B,Hu YW,Krajden M,Scalia V,Byrne SK,Boychuk LR,Klein J

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:A simple and rapid slide Polybrene method (SP) for pretransfusion compatibility testing is described. SP is particularly suitable for use in developing countries where, due to limited resources, centrifuges and biologic reagents may not be readily available. STUDY DESIGN AND METHODS:The original manual Poly...

journal_title：Transfusion

authors： Lin M

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:In 2009 the Mirasol Pathogen Reduction Technology (PRT) was introduced to the routine blood component production of the Regional Blood Transfusion Center in Warsaw (RBTCW). The goal of this study was to investigate the safety of Mirasol-treated blood components. STUDY DESIGN AND METHODS:The accumulated pass...

journal_title：Transfusion

authors： Łętowska M,Przybylska Z,Piotrowski D,Lachert E,Rosiek A,Rzymkiewicz L,Cardoso M

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Immunomodulatory effects of UV light have increasingly become a focus in transfusion medicine, BMT and transplantation immunology. In the transplant setting, the use of UVB radiation may reduce or abolish T-cell activation without compromising either bone marrow (BM) engraftment or graft-versus-leukemia effe...

journal_title：Transfusion

authors： Lankford KV,Mosunjac M,Hillyer CD

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:The AMICUS (Fenwal, Inc.) was cleared in the United States for platelet (PLT) and plasma collection in 1996 with subsequent clearances for the collection of other blood products. Although not previously used for therapeutic plasma exchange (TPE), new disposables, software, and hardware were developed to enab...

journal_title：Transfusion

authors： Winters JL,Burgstaler EA,Gottschall JL,Balogun RA,Houghton JR,Lee WJ,Snyder EL

更新日期：2013-12-01 00:00:00

abstract：:Coagulopathy after traumatic brain injury (TBI) is frequent and represents a powerful predictor related to outcome and prognosis. The complex pathophysiological mechanisms of the coagulopathy of TBI are multifactorial and remain still undefined. The nature of the coagulation abnormalities differs between severe TBI an...

journal_title：Transfusion

authors： Maegele M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Hypothermic storage transforms red blood cells (RBC) from smooth biconcave discocytes into increasingly spherical spiculated echinocytes and, ultimately, fragile spherocytes (S). Individual cells undergo this transformation at different rates, producing a heterogeneous mixture of RBCs at all stages of echino...

journal_title：Transfusion

authors： Lu M,Shevkoplyas SS

更新日期：2020-08-04 00:00:00

abstract：BACKGROUND:Nucleic acid testing (NAT) for human immunodeficiency virus (HIV) and hepatitis C virus (HCV) was introduced for blood donation screening in the United States in 1999. This study analyzes temporal trends of these two infections since NAT introduction. STUDY DESIGN AND METHODS:Donation data from 1999 to 2008...

journal_title：Transfusion

authors： Zou S,Dorsey KA,Notari EP,Foster GA,Krysztof DE,Musavi F,Dodd RY,Stramer SL

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:In Africa, RHD alleles have not been fully characterized. The purpose of this study was to identify inactive and active RHD alleles at the molecular level in Congolese cohorts. STUDY DESIGN AND METHODS:Blood samples were collected from people living in central Congo populated by Teke ethnic group. A total o...

journal_title：Transfusion

authors： Touinssi M,Chapel-Fernandes S,Granier T,Bokilo A,Bailly P,Chiaroni J

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Our goal is to minimize unnecessary cytomegalovirus (CMV)-seronegative blood transfusion to preserve the CMV-seronegative blood inventory for patients who are identified as CMV seronegative. STUDY DESIGN AND METHODS:We implemented a CMV antibody reflex testing protocol for patients who require CMV-compatibl...

journal_title：Transfusion

authors： Fontaine MJ,Jurado C,Miller E,Viele M,Goodnough LT

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Drug-induced immune pancytopenia is considered an uncommon disorder. CASE REPORT:A 76-year-old woman with metastatic gastric adenocarcinoma received 15 cycles of FOLFOX-6 (oxaliplatin/folinic acid/fluorouracil) with a complete response. Upon disease progression, she was restarted on FOLFOX; during the seven...

journal_title：Transfusion

authors： Fontão-Wendel R,Hoff PM,Lazar A,Freitas D,Novis Y,Patah P,Tsujita M,Balthazar A,Pierroti M,Wendel S

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Serious complications of blood donation are rare. Reported here is a significant vascular event that resulted from whole-blood phlebotomy and required surgical repair. CASE REPORT:A 49-year-old woman donated whole blood without incident in November 1992, but reported ecchymosis and tenderness in the antecub...

journal_title：Transfusion

authors： Popovsky MA,McCarthy S,Hawkins RE

更新日期：1994-03-01 00:00:00

abstract：:Critically ill neonatal infants receive frequent small-volume red cell (RBC) transfusions for replacement of blood drawn for laboratory analysis or for treatment of symptomatic anemia secondary to underlying medical conditions and/or a relative bleeding diathesis. Retrospective review of transfusion practice in a hosp...

journal_title：Transfusion

authors： Cook S,Gunter J,Wissel M

更新日期：1993-05-01 00:00:00

abstract：:Tunneled central venous catheters with ports are increasingly used for therapeutic apheresis procedures. Vortex ports have been used as access for therapeutic apheresis procedures, but are not ideal for therapeutic plasma exchange (TPE) procedures due to lower flow rates. We performed an in vitro experiment to compare...

journal_title：Transfusion

authors： De Simone N,Sarode R

更新日期：2018-02-01 00:00:00

abstract：:Iron stores were observed in 57 healthy elderly volunteers, between 63 and 77 years of age, who donated 5 units of blood over approximately 1 year. An equal number of nondonors who contributed approximately 7 mL of blood at each visit for iron status measurements only were seen at the same frequency as the donor popul...

journal_title：Transfusion

authors： Garry PJ,VanderJagt DJ,Wayne SJ,Koehler KH,Rhyne RL,Simon TL

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:Bacterial contamination of blood components remains a major cause of sepsis in transfusion medicine. Between 2006 and 2010 in the 5 years before the introduction of bacterial screening of platelet (PLT) components by National Health Service Blood and Transplant (NHSBT), seven cases of PLT component-associate...

journal_title：Transfusion

authors： McDonald C,Allen J,Brailsford S,Roy A,Ball J,Moule R,Vasconcelos M,Morrison R,Pitt T

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Besides ABO and RH, the KEL blood group system, including the two antithetical antigens KEL1 and KEL2, is the most important owing to the frequent appearance of anti-KEL alloantibodies and their considerable clinical significance. So far, only limited information was available on KEL variant alleles determin...

journal_title：Transfusion

authors： Körmöczi GF,Wagner T,Jungbauer C,Vadon M,Ahrens N,Moll W,Mühlbacher A,Ozgül-Gülce S,Kleinrath T,Kilga-Nogler S,Schönitzer D,Gassner C

更新日期：2007-04-01 00:00:00

abstract：:Anti-Emm, an antibody to a public red cell antigen, was found in the serums of four Emm-propositi and in the serum of the Emm-brother of one of them. Three of the propositi were men, and their antibodies, as well as that of the compatible brother, were believed to be "naturally occurring." Since there are two Emm-sibl...

journal_title：Transfusion

authors： Daniels GL,Taliano V,Klein MT,McCreary J

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:To quantify the impact of the US President's Emergency Plan for AIDS Relief (PEPFAR) on the risk of HIV transmission through infected blood donations in countries supported by PEPFAR blood safety programs. METHODS:Data reported to the World Health Organization Global Database on Blood Safety were analyzed f...

journal_title：Transfusion

authors： Mili FD,Teng Y,Shiraishi RW,Yu J,Bock N,Drammeh B,Watts DH,Benech I

更新日期：2021-01-28 00:00:00

abstract：BACKGROUND:On rare occasions, upon thawing of stored cryoprecipitate components, clots are observed on visual inspection. Although it has been assumed that the clot reflects fibrinogen to fibrin conversion, there are few published studies that document that this assumption is correct. Our studies were conducted to furt...

journal_title：Transfusion

authors： MacPhee M,Wilmer B,Beall D,Moroff G

更新日期：2013-03-01 00:00:00

abstract：:The potassium load of transfused blood must be minimized. We have compared the total plasma potassium content of units of CPD-preserved stored whole blood (SWB), stored packed cells (SPC), and packed cells prepared from stored whole blood (WB-PC). Plasma potassium concentrations, unit weights, and hematocrits of 20 un...

journal_title：Transfusion

authors： Michael JM,Dorner I,Bruns D,Ladenson JH,Sherman LA

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND:Hemolytic disease of the fetus and newborn (HDFN) is a severe disease, resulting from maternal red cell (RBC) alloantibodies directed against fetal RBCs. The effect of a first-trimester antibody screening program on the timely detection of HDFN caused by antibodies other than anti-D was evaluated. STUDY DES...

journal_title：Transfusion

authors： Koelewijn JM,Vrijkotte TG,van der Schoot CE,Bonsel GJ,de Haas M

更新日期：2008-05-01 00:00:00

abstract：:The quantity of anti-IgG bound at equilibrium to cell-bound anti-D failed to increase with enzymatic modification of intact red blood cells. This contrasts with results obtained by immunoelectronmicroscopy with unsealed red blood cell ghosts. Ghosts derived from enzyme-modified, anti-D-sensitized intact red blood cell...

journal_title：Transfusion

authors： Rearden A,Masouredis SP

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND:There is little knowledge how different hold times of hyperconcentrated platelet (PLT) suspensions (HPSs) before the addition of platelet additive solution (PAS) might affect PLT quality. We compared the in vitro quality of single-donor PLT concentrates (SDPs) with immediate or delayed PAS addition and studi...

journal_title：Transfusion

authors： Ringwald J,Tully S,Geier C,Hauck B,Weiss D,Callaert M,Eckstein R

更新日期：2012-06-01 00:00:00

abstract：:Human T-cell leukemia viruses (HTLV-1 and HTLV-2) are associated with a variety of human diseases, including some severe ones. Transfusion transmission of HTLV through cellular blood components is undeniable. HTLV screening of blood donations became mandatory in different countries to improve the safety of blood suppl...

journal_title：Transfusion

authors： Marano G,Vaglio S,Pupella S,Facco G,Catalano L,Piccinini V,Liumbruno GM,Grazzini G

更新日期：2016-01-01 00:00:00