Asymptomatic aneurysm of the interatrial septum.

abstract：OBJECTIVES:We evaluated the short- and long-term effects of flosequinan in 47 patients with severe heart failure despite ongoing captopril treatment. BACKGROUND:There have been no previous evaluations of the long-term hemodynamic effects of any direct-acting vasodilator in patients with heart failure receiving an angi...

journal_title：Journal of the American College of Cardiology

authors： Gottlieb SS,Kukin ML,Penn J,Fisher ML,Cines M,Medina N,Yushak M,Taylor M,Packer M

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVES:Our aim was to assess the prognostic value of midregional pro-atrial natriuretic peptide (MR-proANP) in patients after acute myocardial infarction (AMI). BACKGROUND:Multimarker strategies may assist risk stratification after AMI. Midregional pro-atrial natriuretic peptide is a newly described stable fragmen...

journal_title：Journal of the American College of Cardiology

authors： Khan SQ,Dhillon O,Kelly D,Squire IB,Struck J,Quinn P,Morgenthaler NG,Bergmann A,Davies JE,Ng LL

更新日期：2008-05-13 00:00:00

abstract：:Despite the numerous documented benefits of cardiac resynchronization therapy (CRT), a significant proportion of patients undergoing CRT do not demonstrate symptomatic or morphologic improvement, triggering the search to improve targeting of this therapy. Many studies now support direct assessment of mechanical dyssyn...

journal_title：Journal of the American College of Cardiology

authors： Lardo AC,Abraham TP,Kass DA

更新日期：2005-12-20 00:00:00

abstract：OBJECTIVES:The purpose of this study was to investigate the expression of perforin and T-cell intracellular antigen-1, two crucial components of lymphocyte-mediated cytotoxicity, in endomyocardial biopsies from patients with idiopathic dilated cardiomyopathy. BACKGROUND:Previous reports have demonstrated the presence ...

journal_title：Journal of the American College of Cardiology

authors： Badorff C,Noutsias M,Kühl U,Schultheiss HP

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVES:The primary objective of this study was to assess the effect of a 6-month testosterone supplementation therapy on functional capacity and insulin resistance in female patients with chronic heart failure (CHF). BACKGROUND:Patients with CHF show decreased exercise capacity and insulin sensitivity. Testosteron...

journal_title：Journal of the American College of Cardiology

authors： Iellamo F,Volterrani M,Caminiti G,Karam R,Massaro R,Fini M,Collins P,Rosano GM

更新日期：2010-10-12 00:00:00

abstract：OBJECTIVES:The goal of this study was to compare myocardial perfusion reserve (MPR) before and after long-term treatment with lisinopril and losartan in patients with hypertension and left ventricular hypertrophy (LVH). BACKGROUND:Studies have suggested that treatment with angiotensin-converting enzyme inhibitors (ACE...

journal_title：Journal of the American College of Cardiology

authors： Akinboboye OO,Chou RL,Bergmann SR

更新日期：2002-08-21 00:00:00

abstract：:The impact of right bundle branch block on long-term prognosis after anterior wall myocardial infarction is unclear. In 932 patients with Q wave anterior infarction, the short- and long-term prognostic significance of the presence of right bundle branch block was analyzed. Compared with 754 patients without block, 178...

journal_title：Journal of the American College of Cardiology

authors： Ricou F,Nicod P,Gilpin E,Henning H,Ross J Jr

更新日期：1991-03-15 00:00:00

abstract：OBJECTIVES:We describe the baseline characteristics and clinical course of patients who had an acute myocardial infarction (AMI) during their hospital stay. BACKGROUND:In comparison with patients who had an AMI outside of the hospital (prehospital AMI), the data on patients who had an AMI in the hospital are poorly de...

journal_title：Journal of the American College of Cardiology

authors： Zahn R,Schiele R,Seidl K,Kapp T,Glunz HG,Jagodzinski E,Voigtländer T,Gottwik M,Berg G,Thomas H,Senges J

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVES:This is a randomized controlled study of anemic patients with severe congestive heart failure (CHF) to assess the effect of correction of the anemia on cardiac and renal function and hospitalization. BACKGROUND:Although mild anemia occurs frequently in patients with CHF, there is very little information abo...

journal_title：Journal of the American College of Cardiology

authors： Silverberg DS,Wexler D,Sheps D,Blum M,Keren G,Baruch R,Schwartz D,Yachnin T,Steinbruch S,Shapira I,Laniado S,Iaina A

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVES:We evaluated the endothelial and vascular smooth muscle function in patients with chronic severe anemia to determine whether increased basal nitric oxide levels contribute to the systemic vasodilation and high cardiac output seen in these patients. BACKGROUND:Patients with chronic severe anemia have a high ...

journal_title：Journal of the American College of Cardiology

authors： Anand IS,Chandrashekhar Y,Wander GS,Chawla LS

更新日期：1995-05-01 00:00:00

abstract：OBJECTIVES:The Air Primary Angioplasty in Myocardial Infarction (PAMI) study was designed to determine the best reperfusion strategy for patients with high-risk acute myocardial infarction (AMI) at hospitals without percutaneous transluminal coronary angioplasty (PTCA) capability. BACKGROUND:Previous studies have sugg...

journal_title：Journal of the American College of Cardiology

authors： Grines CL,Westerhausen DR Jr,Grines LL,Hanlon JT,Logemann TL,Niemela M,Weaver WD,Graham M,Boura J,O'Neill WW,Balestrini C,Air PAMI Study Group.

更新日期：2002-06-05 00:00:00

abstract：OBJECTIVES:The aim of this study was to compare treadmill exercise (TEX) and dipyridamole stress on the uptake and retention of N-13 ammonia. BACKGROUND:Size and severity of stress-induced myocardial perfusion defects are clinically important. Because ammonia uptake and retention seems to be related to perfusion, viab...

journal_title：Journal of the American College of Cardiology

authors： Chow BJ,Beanlands RS,Lee A,DaSilva JN,deKemp RA,Alkahtani A,Ruddy TD

更新日期：2006-01-17 00:00:00

abstract：OBJECTIVES:The present work was designed to provide an initial characterization of M cells in the normal human heart. BACKGROUND:Recent studies have uncovered a unique population of cells in the midmyocardial region of the canine ventricle. These cells, named M cells, were found to possess electrophysiologic features ...

journal_title：Journal of the American College of Cardiology

authors： Drouin E,Charpentier F,Gauthier C,Laurent K,Le Marec H

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVES:This study sought to evaluate the associations between different measures of obesity and prevalent atherosclerosis in a large population-based cohort. BACKGROUND:Although obesity is associated with cardiovascular mortality, it is unclear whether this relationship is mediated by increased atherosclerotic bur...

journal_title：Journal of the American College of Cardiology

authors： See R,Abdullah SM,McGuire DK,Khera A,Patel MJ,Lindsey JB,Grundy SM,de Lemos JA

更新日期：2007-08-21 00:00:00

abstract：:To determine the rate of induction, specificity and evolution of electrically induced postmyocardial infarction ventricular arrhythmias, 10 dogs that underwent a sham operation and 20 dogs with experimental transmural apical myocardial infarction underwent serial closed chest electrophysiologic studies with programmed...

journal_title：Journal of the American College of Cardiology

authors： Garan H,Ruskin JN,McGovern B,Grant G

更新日期：1985-05-01 00:00:00

abstract：OBJECTIVES:Our goal was to compare histologically the mechanisms producing congenital complete heart block in normally structured hearts and in hearts with isomerism of the atrial appendages. BACKGROUND:It is known that several different histologic patterns can underscore the existence of congenital complete heart blo...

journal_title：Journal of the American College of Cardiology

authors： Ho SY,Fagg N,Anderson RH,Cook A,Allan L

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVES:A pressure overload model was developed to simulate aortic stenosis and assess caspase activity during the transition to heart failure. BACKGROUND:Cardiomyocyte apoptosis is implicated in the pathogenesis of heart failure, and caspase activation is central to this pathophysiological process. METHODS:A tota...

journal_title：Journal of the American College of Cardiology

authors： Moorjani N,Ahmad M,Catarino P,Brittin R,Trabzuni D,Al-Mohanna F,Narula N,Narula J,Westaby S

更新日期：2006-10-03 00:00:00

abstract：OBJECTIVES:the purpose of this study was to evaluate the association of the percentage of platelet inhibitory response to clopidogrel as assessed by modified thromboelastography with bleeding and transfusion requirement after off-pump coronary artery bypass graft (OPCABG) surgery. BACKGROUND:Interindividual variabilit...

journal_title：Journal of the American College of Cardiology

authors： Kwak YL,Kim JC,Choi YS,Yoo KJ,Song Y,Shim JK

更新日期：2010-12-07 00:00:00

abstract：:It has been shown that streptokinase administration at the time of acute myocardial infarction reduces mortality significantly, and that this reduction in mortality should be related to salvage of jeopardized myocardium and preservation of left ventricular function. To better define the relation between thrombolytic t...

journal_title：Journal of the American College of Cardiology

authors： Marino P,Zanolla L,Zardini P

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND:The BAG3 (BLC2-associated athanogene 3) gene codes for an antiapoptotic protein located on the sarcomere Z-disc. Mutations in BAG3 are associated with dilated cardiomyopathy (DCM), but only a small number of cases have been reported to date, and the natural history of BAG3 cardiomyopathy is poorly understood...

journal_title：Journal of the American College of Cardiology

authors： Domínguez F,Cuenca S,Bilińska Z,Toro R,Villard E,Barriales-Villa R,Ochoa JP,Asselbergs F,Sammani A,Franaszczyk M,Akhtar M,Coronado-Albi MJ,Rangel-Sousa D,Rodriguez-Palomares JF,Jiménez-Jáimez J,Garcia-Pinilla JM,Ripoll-Ve

更新日期：2018-11-13 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate whether multiple biomarkers contribute to improved coronary heart disease (CHD) risk prediction in post-menopausal women compared with assessment using traditional risk factors (TRFs) only. BACKGROUND:The utility of newer biomarkers remains uncertain when added to pr...

journal_title：Journal of the American College of Cardiology

authors： Kim HC,Greenland P,Rossouw JE,Manson JE,Cochrane BB,Lasser NL,Limacher MC,Lloyd-Jones DM,Margolis KL,Robinson JG

更新日期：2010-05-11 00:00:00

abstract：OBJECTIVES:We sought to examine the effects of endurance training on the ultrastructural characteristics of skeletal muscle in heart transplant recipients (HTRs) and age-matched control subjects (C). BACKGROUND:Deconditioning is one of the factors involved in the peripheral limitation of exercise capacity of HTRs, and...

journal_title：Journal of the American College of Cardiology

authors： Lampert E,Mettauer B,Hoppeler H,Charloux A,Charpentier A,Lonsdorfer J

更新日期：1998-08-01 00:00:00

abstract：:The patient with chronic kidney disease and coronary artery disease (CAD) presents special challenges. This report reviews the scope of the challenge, the hostile internal milieu predisposing to CAD and cardiac events, management issues, unresolved dilemmas, and the need for randomized trials to allow for evidence-bas...

journal_title：Journal of the American College of Cardiology

authors： Gupta R,Birnbaum Y,Uretsky BF

更新日期：2004-10-06 00:00:00

abstract：OBJECTIVES:We hypothesized that an amlodipine-based regimen would have more favorable effects on left ventricular (LV) diastolic function. BACKGROUND:Different antihypertensive therapies may vary in their effect on LV diastolic function. METHODS:The HACVD (Hypertension Associated Cardiovascular Disease) substudy of A...

journal_title：Journal of the American College of Cardiology

authors： Tapp RJ,Sharp A,Stanton AV,O'Brien E,Chaturvedi N,Poulter NR,Sever PS,Thom SA,Hughes AD,Mayet J,ASCOT Investigators.

更新日期：2010-04-27 00:00:00

abstract：BACKGROUND:Poor adherence to medication regimens is common, potentially contributing to the occurrence of related disease. OBJECTIVES:The authors sought to assess the risk of fatal stroke associated with nonadherence to statin and/or antihypertensive therapy. METHODS:We conducted a population-based study using electr...

journal_title：Journal of the American College of Cardiology

authors： Herttua K,Martikainen P,Batty GD,Kivimäki M

更新日期：2016-04-05 00:00:00

abstract：BACKGROUND:Pheochromocytoma is associated with catecholamine-induced cardiac toxicity, but the extent and nature of cardiac involvement in clinical cohorts is not well-characterized. OBJECTIVES:This study characterized the cardiac phenotype in patients with pheochromocytoma using cardiac magnetic resonance (CMR). MET...

journal_title：Journal of the American College of Cardiology

authors： Ferreira VM,Marcelino M,Piechnik SK,Marini C,Karamitsos TD,Ntusi NAB,Francis JM,Robson MD,Arnold JR,Mihai R,Thomas JDJ,Herincs M,Hassan-Smith ZK,Greiser A,Arlt W,Korbonits M,Karavitaki N,Grossman AB,Wass JAH,Neubaue

更新日期：2016-05-24 00:00:00

abstract：OBJECTIVES:We sought to assess the ability of preload-adjusted maximal power measured by echocardiographic automated border detection (ABD) to quantify left ventricular (LV) contractility by determining the effects of alterations in preload, afterload and contractile state. BACKGROUND:Preload-adjusted maximal power ca...

journal_title：Journal of the American College of Cardiology

authors： Mandarino WA,Pinsky MR,Gorcsan J 3rd

更新日期：1998-03-15 00:00:00

abstract：OBJECTIVE:To determine predictors of systolic anterior motion and left ventricular outflow tract obstruction (SAM/LVOTO) after mitral valve repair (MVRep) in patients with myxomatous mitral valve disease. BACKGROUND:Mechanisms for the development of SAM/LVOTO after MVRep have been described; however, predictors of thi...

journal_title：Journal of the American College of Cardiology

authors： Maslow AD,Regan MM,Haering JM,Johnson RG,Levine RA

更新日期：1999-12-01 00:00:00

abstract：:Acute myocardial ischemia is known to cause impairment of both left ventricular systolic and diastolic function. To further investigate these changes as well as their relation to common clinical variables (electrocardiographic [ECG] changes and chest pain), 32 patients were evaluated with Doppler echocardiography duri...

journal_title：Journal of the American College of Cardiology

authors： Labovitz AJ,Lewen MK,Kern M,Vandormael M,Deligonal U,Kennedy HL

更新日期：1987-10-01 00:00:00

abstract：OBJECTIVES:To test the hypothesis that the cardiac insulin-like growth factor-1 (IGF-1) system is up-regulated in the failing heart, we measured the pericardial (cardiac) and plasma (circulating) IGF-1 levels in coronary artery disease patients. BACKGROUND:Local IGF-1 systems are regulated differently from the systemi...

journal_title：Journal of the American College of Cardiology

authors： Abe N,Matsunaga T,Kameda K,Tomita H,Fujiwara T,Ishizaka H,Hanada H,Fukui K,Fukuda I,Osanai T,Okumura K

更新日期：2006-10-03 00:00:00