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The effect of progesterone on the spontaneous interictal spike evoked by the application of penicillin to the cat's cerebral cortex.

Abstract：

:The effect of intravenous infusion of progesterone and Mebumal (ACO, Sweden; penotobarbital, INN) on the frequency and amplitude of the spontaneous interictal spikes from a penicillin focus in the cerebral cortex was investigated in ovariectomized cats anaesthetized with chloralose. The plasma concentration of progesterone was determined. It was found that the generation of penicillin spikes was depressed by progesterone in plasma concentrations as low as 40 ng/ml. Equimolar doses of Mebumal were less effective.

journal_name

J Neurol Sci

journal_title

Journal of the neurological sciences

authors

Landgren S,Bäckström T,Kalistratov G

doi

10.1016/0022-510x(78)90166-1

subject

Has Abstract

pub_date

1978-03-01 00:00:00

pages

119-33

issue

1

eissn

0022-510X

issn

1878-5883

pii

0022-510X(78)90166-1

journal_volume

36

pub_type

杂志文章

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