Discrete lesions in the sensorimotor control system. A clinical-topographical study of lacunar infarcts.

Abstract:

:In 50 patients with computed tomography-verified small, deep, lacunar, infarcts from a prospective stroke registry, we studied the lesion site in relationship with the clinical syndromes pure motor stroke, sensorimotor stroke and ataxic hemiparesis. Seventy per cent (95% confidence interval: 57-83%) of the lesions were located in the posterior limb of the internal capsule or adjacent paraventricular region, affecting the corticospinal tract in pure motor stroke, as well as the thalamocortical tract in sensorimotor stroke, and the cerebellar (dentato(rubro)thalamocortical and corticopontocerebellar) pathways in ataxic hemiparesis. This most frequently involved area is supplied by the anterior choroidal artery, indicating that this artery is the predominant deep, penetrating artery involved in small vessel disease causing lacunar stroke syndromes.

journal_name

J Neurol Sci

authors

Boiten J,Lodder J

doi

10.1016/0022-510x(91)90138-w

subject

Has Abstract

pub_date

1991-10-01 00:00:00

pages

150-4

issue

2

eissn

0022-510X

issn

1878-5883

pii

0022-510X(91)90138-W

journal_volume

105

pub_type

杂志文章
  • Multiple paraneoplastic syndromes: myasthenia gravis, vitiligo, alopecia areata, and oral lichen planus associated with thymoma.

    abstract::Thymomas are associated with paraneoplastic autoimmune diseases at a high frequency. It is rare that four paraneoplastic autoimmune disorders co-occur in a single patient. We describe a thymoma patient with diagnoses of myasthenia gravis, vitiligo, alopecia areata, and oral lichen planus associated with a thymoma. Aft...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2011.05.038

    authors: Qiao J,Zhou G,Ding Y,Zhu D,Fang H

    更新日期:2011-09-15 00:00:00

  • Th2 shift in mononeuritis multiplex and increase of Th2 cells in chronic inflammatory demyelinating polyneuropathy: an intracellular cytokine analysis.

    abstract::To elucidate the T helper 1 (Th1)/T helper 2 (Th2) balance in various inflammatory neuropathies, we measured the ratio of intracellular interferon-gamma (IFN-gamma)-positive to IL-4-positive cells (intracellular IFN-gamma/IL-4 ratio) by flow cytometry in peripheral blood CD4(+) T cells of 14 patients with mononeuritis...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/s0022-510x(01)00603-7

    authors: Horiuchi I,Ochi H,Murai H,Osoegawa M,Minohara M,Furuya H,Kira J

    更新日期:2001-12-15 00:00:00

  • Usefulness of prolonged video-EEG monitoring in the elderly.

    abstract::The diagnosis of epilepsy in the elderly can be difficult. We sought to determine whether video-EEG monitoring (VEEG) is useful in the diagnosis and management of elderly patients with epilepsy. We reviewed the medical records of 20 consecutive patients, over 60 years of age, selected from a total of 1423 patients ref...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/0022-510x(96)00092-5

    authors: Lancman ME,O'Donovan C,Dinner D,Coelho M,Lüders HO

    更新日期:1996-10-01 00:00:00

  • A magnetization transfer study of white matter in siblings of multiple sclerosis patients.

    abstract::In this study, we evaluated magnetization transfer ratio values in the brain white matter of siblings of multiple sclerosis (MS) patients and compared them to those obtained in sex- and age-matched normal controls. No statistically significant difference was found between the two groups for all the white matter areas ...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/s0022-510x(96)05322-1

    authors: Filippi M,Campi A,Martino G,Colombo B,Comi G

    更新日期:1997-04-15 00:00:00

  • Defective electron transfer in complexes I and IV in patients with aceruloplasminemia.

    abstract::Aceruloplasminemia is a disorder of iron metabolism caused by mutations in the ceruloplasmin gene. It is characterized by progressive neurodegeneration of the retina, basal ganglia, dentate nucleus and cerebral cortex in association with iron accumulation in these tissues. Enzyme activities in the mitochondrial respir...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/s0022-510x(00)00452-4

    authors: Kohno S,Miyajima H,Takahashi Y,Suzuki H,Hishida A

    更新日期:2000-12-15 00:00:00

  • Unusual clinical findings and Complex III deficiency in a family with myotonic dystrophy.

    abstract::Myotonic dystrophy type 1 (DM1), an autosomal dominant disease characterized by a CTG expansion in the 3' region of the DMPK gene in chromosome 19, is a highly heterogeneous disease. In this study, we present a family with early onset-classical type DM, and a homogeneous phenotype highlighted by severe neuromuscular s...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/s0022-510x(02)00442-2

    authors: Seijo-Martínez M,Castro del Río M,Campos Y,Palau F,Arenas J,Teijeira S,Fernández Hojas R,Navarro C

    更新日期:2003-04-15 00:00:00

  • Reliability of TMS motor evoked potentials in quadriceps of subjects with chronic hemiparesis after stroke.

    abstract::Transcranial magnetic stimulation (TMS) non-invasively measures excitability of central motor pathways in humans and is used to characterize neuroplasticity after stroke. Using TMS to index lower extremity neuroplasticity after gait rehabilitation requires test-retest reliability. This study assesses the reliability o...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2008.09.012

    authors: Wheaton LA,Villagra F,Hanley DF,Macko RF,Forrester LW

    更新日期:2009-01-15 00:00:00

  • Discrepant relationships between admission blood pressure and mortality in different stroke subtypes.

    abstract::The relationship between blood pressure(BP) and clinical outcome in patients with acute stroke is still controversial. The present study aimed to elucidate the impact of admission blood pressure on mortality in patients with acute stroke of different subtypes. Data were from ChinaQUEST (QUality Evaluation of Stroke Ca...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jns.2017.09.032

    authors: Liu Y,Yang Y,Jin H,Fan C,Lv P,Sun W,Peng Q,Zhao M,Jin DK,Wang J,Wong LKS,Anderson CS,Zheng L,Huang Y,ChinaQUEST (Quality Evaluation of Stroke Care and Treatment) Investigators.

    更新日期:2017-12-15 00:00:00

  • Planning genetic studies on primary adult-onset dystonia: sample size estimates based on examination of first-degree relatives.

    abstract::Primary adult-onset dystonia is thought to be partly genetic, but families large enough for a genome wide search are difficult to find. We examined the first-degree relatives of 76 primary adult-onset dystonia patients to assess the feasibility of model-free nonparametric methods that allow either screening of candida...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2006.08.009

    authors: Defazio G,Martino D,Aniello MS,Masi G,Gigante A,Bhatia K,Livrea P,Berardelli A

    更新日期:2006-12-21 00:00:00

  • Therapy adherence issues in Parkinson's disease.

    abstract::The response to dopamine replacement therapy in patients with degenerative parkinsonism is variable. Reasons for a poor therapy response include the type of parkinsonism, comorbidities, and differential effects on clinical features. An additional explanation, which has received much less attention, is sub-optimal ther...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章,评审

    doi:10.1016/j.jns.2009.08.053

    authors: Grosset D,European PD Therapy Compliance Study Group.

    更新日期:2010-02-15 00:00:00

  • Subclinical phenotypic expressions in heterozygous females of X-linked recessive bulbospinal neuronopathy.

    abstract::Four of 8 definite heterozygous female carriers determined by PCR amplification of tandem CAG repeat of the AR gene, from 4 families of X-linked recessive bulbospinal neuronopathy (X-BSNP) showed extensive high amplitude motor unit potentials in examined muscles although all subjects were neurologically normal. Plasma...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/0022-510x(93)90157-t

    authors: Sobue G,Doyu M,Kachi T,Yasuda T,Mukai E,Kumagai T,Mitsuma T

    更新日期:1993-07-01 00:00:00

  • Postural control, falls and fear of falling in people with multiple sclerosis without mobility aids.

    abstract::The purpose of the study was to determine the relationship between static postural control parameters to fear of falling and falling history in people with multiple sclerosis (MS) without mobility assistive devices. One-hundred and seven relapsing-remitting patients diagnosed with MS, 62 women aged 42.8 (S.D.=12.0), p...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2013.09.029

    authors: Kalron A,Achiron A

    更新日期:2013-12-15 00:00:00

  • Improvement in motor evoked potentials and clinical course post-steroid therapy in multiple sclerosis.

    abstract::Motor evoked potentials (MEP) were recorded in 23 patients with definite relapsing multiple sclerosis before and after treatment with a short course of high dose of methylprednisolone. MEP were performed together with clinical examination just before treatment, and 6 and 60 days later. The following results were obser...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/0022-510x(92)90049-q

    authors: Salle JY,Hugon J,Tabaraud F,Boulesteix JM,Vallat JM,Dumas M,Poser CM

    更新日期:1992-04-01 00:00:00

  • Neuroprotective effect of diazoxide on brain injury induced by cerebral ischemia/reperfusion during deep hypothermia.

    abstract:OBJECT:The purpose of this study was to determine the effects of diazoxide on apoptosis and the relative mechanisms in a model of brain injury induced by cerebral ischemia/reperfusion (I/R) during deep hypothermia. METHODS:Three-week-old Sprague-Dawley male rats were randomly and equitably divided into sham-operated g...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2007.10.029

    authors: He X,Mo X,Gu H,Chen F,Gu Q,Peng W,Qi J,Shen L,Sun J,Zhang R,Kj Y

    更新日期:2008-05-15 00:00:00

  • Muscle mitochondrial DNA deletion and 31P-NMR spectroscopy alterations in a migraine patient.

    abstract::A 40-year-old female suffering from recurrent migrainous strokes is reported. She did not show any muscle weakness or wasting. Ragged red and cytochrome c oxidase negative fibers were present in the muscle biopsy. Muscle mitochondrial DNA analysis showed a 5 kb deletion, without a point mutation at nucleotide pair 324...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/0022-510x(91)90308-t

    authors: Bresolin N,Martinelli P,Barbiroli B,Zaniol P,Ausenda C,Montagna P,Gallanti A,Comi GP,Scarlato G,Lugaresi E

    更新日期:1991-08-01 00:00:00

  • Seasonal variations of 25-OH vitamin D serum levels are associated with clinical disease activity in multiple sclerosis patients.

    abstract::Low 25-hydroxy vitamin D (25-[OH]-D) serum concentrations have been associated with higher disease activity in multiple sclerosis (MS) patients. In a large cross-sectional study we assessed the vitamin D status in MS patients in relation to seasonality and relapse rate. 415 MS-patients (355 relapsing-remitting MS and ...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2017.01.059

    authors: Hartl C,Obermeier V,Gerdes LA,Brügel M,von Kries R,Kümpfel T

    更新日期:2017-04-15 00:00:00

  • Serum anti-brain endothelium antibodies and cognitive assessment in patients with Binswanger's encephalopathy.

    abstract::The pathogenic mechanism underlying the vascular changes in Binswanger's encephalopathy (BE) is unknown. To test whether alterations of the humoral immunity may lead to endothelium damage, we analyzed serum levels of anti-brain endothelium antibodies (ABEA) (IgG and IgM) in 16 BE patients, 19 subjects with ischemic va...

    journal_title:Journal of the neurological sciences

    pub_type: 临床试验,杂志文章

    doi:10.1016/0022-510x(94)00215-a

    authors: Annunziata P,Cioni C,Moschini F,Riccucci A,Guazzi GC

    更新日期:1995-01-01 00:00:00

  • Myophosphorylase deficiency associated with a defect in complex I of the mitochondrial respiratory chain.

    abstract::We studied a 21-year-old patient with clinical, biochemical and histochemical evidence of myophosphorylase deficiency and unusual repetitive episodes of pigmenturia. His muscle biopsy also revealed morphological signs of mitochondrial proliferation and a defect of complex I of the respiratory chain. His mother had exe...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/s0022-510x(98)00263-9

    authors: Rubio JC,Martín MA,Bautista J,Campos Y,Segura D,Cabello A,Chinchón I,Arenas J

    更新日期:1998-12-11 00:00:00

  • Location-specific characteristics of perivascular spaces as the brain's interstitial fluid drainage system.

    abstract:PURPOSE:Brain interstitial fluid plays an important role in the excretion of metabolic waste products into the cerebrospinal fluid through perivascular spaces (PVS). To investigate the normal function of PVS in healthy elderly individuals, we assessed the relationship between PVS and white matter hyperintensity (WMH) o...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2019.01.022

    authors: Yamada S,Ishikawa M,Yamamoto K,Yamaguchi M,Oshima M

    更新日期:2019-03-15 00:00:00

  • Long-term effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal dopamine content in young and mature mice.

    abstract::Long-term effects of MPTP on striatal dopamine (DA) content and the influence of aging on the recovery were investigated in mice. Male C57BL/6J mice, young (2-month-old) and mature (10-month-old), were used. Two different dosage schedules of MPTP, i.e., 4 doses subcutaneous injections of 20 mg/kg each, and 4 doses sub...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/0022-510x(87)90125-0

    authors: Saitoh T,Niijima K,Mizuno Y

    更新日期:1987-02-01 00:00:00

  • Neurotransmitter amino acids in cerebrospinal fluid of patients with Parkinson's disease.

    abstract::We measured the CSF and plasma levels of glutamate, glutamine, aspartate (only in plasma), asparagine, glutamine, glycine and GABA in 31 patients with Parkinson's disease and in 45 matched controls. We used an ion-exchange chromatography method. When compared to controls, PD patients had similar CSF levels of glutamat...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/0022-510x(96)00115-3

    authors: Jiménez-Jiménez FJ,Molina JA,Vargas C,Gómez P,Navarro JA,Benito-León J,Ortí-Pareja M,Gasalla T,Cisneros E,Arenas J

    更新日期:1996-09-15 00:00:00

  • Cerebrovascular reactivity over time course in healthy subjects.

    abstract:INTRODUCTION:Cerebrovascular reactivity (CVR) reflects the compensatory dilatory capacity of cerebral arterioles to a dilatory stimulus and is an important mechanism for maintaining constant cerebral blood flow. Many pathological conditions are associated with an impaired CVR thus contributing to a higher risk of cereb...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2006.06.009

    authors: Schwertfeger N,Neu P,Schlattmann P,Lemke H,Heuser I,Bajbouj M

    更新日期:2006-11-15 00:00:00

  • Development of a clinical score, PANDA, to predict delirium in stroke care unit.

    abstract:BACKGROUND AND PURPOSE:Delirium frequently complicates acute stroke and worsens outcomes. Because delirium is potentially preventable, predicting its occurrence is essential. Although several prediction scores have been proposed, nurses need to quickly predict delirium in stroke care units (SCUs). We aimed to develop a...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2020.116956

    authors: Nakamizo T,Kanda T,Kudo Y,Sugawara E,Hashimoto E,Okazaki A,Usuda M,Nagai T,Hara H,Johkura K

    更新日期:2020-08-15 00:00:00

  • The concept of vascular cognitive impairment.

    abstract::Vascular dementia (VaD) is increasingly recognised to reflect an outmoded concept in that it identifies cases too late for preventive therapy to have an opportunity to prevent the development of dementia and uses a cognitive paradigm inappropriately based on Alzheimer's disease. A replacement is urgently required and ...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章,评审

    doi:10.1016/s0022-510x(02)00253-8

    authors: Bowler JV

    更新日期:2002-11-15 00:00:00

  • Orthostatic tachycardia with different onset time in patients with orthostatic intolerance.

    abstract:OBJECTIVE:To investigate whether there is a difference in the neuro-autonomic and hemodynamic parameters in patients with postural tachycardia syndrome (POTS) according to onset time of orthostatic tachycardia during the Head-up tilt (HUT) test. METHODS:We retrospectively reviewed neuro-autonomic and hemodynamic data ...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2018.04.033

    authors: Lee H,Kim HA

    更新日期:2018-07-15 00:00:00

  • Two families with novel missense mutations in COL4A1: When diagnosis can be missed.

    abstract::Mutations in COL4A1, encoding one of the six collagen type IV proteins, cover a wide spectrum of autosomal dominant overlapping phenotypes including porencephaly, small-vessel disease and hemorrhagic stroke, leukoencephalopathy, hereditary angiopathy with nephropathy, aneurysms and muscle cramp (HANAC) syndrome, and W...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2015.03.042

    authors: Giorgio E,Vaula G,Bosco G,Giacone S,Mancini C,Calcia A,Cavalieri S,Di Gregorio E,Rigault De Longrais R,Leombruni S,Pinessi L,Cerrato P,Brusco A,Brussino A

    更新日期:2015-05-15 00:00:00

  • The neurological consequences of explosives.

    abstract::Neurological injuries produced by explosive blasts are the result of a cascade of events that begin with the initial explosion and evolve from the secondary, tertiary, and quaternary effects that the explosion engenders [Lavonis EJ. Blast Injuries. EMedicine.htm]. Only the results of the primary blast are predictable,...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章,评审

    doi:10.1016/j.jns.2006.06.005

    authors: Finkel MF

    更新日期:2006-11-01 00:00:00

  • Relation between Genetic markers and oligoclonal IgG in CSF in optic neuritis.

    abstract::Thirty patients with acute, unilateral optic neuritis (ON), where re-examination after a mean observation period of 5 years did not reveal any aetiology, were investigated with regard to laboratory abnormalities frequently observed in multiple sclerosis. Eleven patients had oligoclonal IgG in CSF. In 5 of these a meas...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/0022-510x(76)90237-9

    authors: Stendahl L,Link H,Möller E,Norrby E

    更新日期:1976-01-01 00:00:00

  • Lipoic acid prevents oxidative stress in vitro and in vivo by an acute hyperphenylalaninemia chemically-induced in rat brain.

    abstract::Phenylketonuria (PKU) is a recessive autosomal disorder caused by a severe deficiency of phenylalanine-4-hydroxilase activity which leads to the accumulation of L-phenylalanine (Phe) in the tissues and plasma of patients. The main clinical features are retarded development and intellectual impairment. Recent studies h...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/j.jns.2010.01.016

    authors: Moraes TB,Zanin F,da Rosa A,de Oliveira A,Coelho J,Petrillo F,Wajner M,Dutra-Filho CS

    更新日期:2010-05-15 00:00:00

  • Immunological relationship between a demyelinating RNA enveloped budding virus (Semliki Forest) and brain glycolipids.

    abstract::A monoclonal antibody (MAb) raised against central nervous system (CNS) myelin (212) and a MAb (308) raised against brain with Semliki Forest virus (SFV) were both found to react against the same CNS glycolipids. Both these MAbs were also found to react strongly with SFV and against certain brain glycolipid fractions ...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章

    doi:10.1016/0022-510x(86)90144-9

    authors: Khalili-Shirazi A,Gregson N,Webb HE

    更新日期:1986-11-01 00:00:00