Therapy for immunologic disease. New ways of using old drugs.

abstract：:According to Cato Institute chairman William A. Niskanen, government-mandated managed competition will fail to control healthcare costs and will pose a serious threat to the quality of American medical care. Mr Niskanen elaborates on this viewpoint in the following remarks, which were originally delivered in a speech....

journal_title：Postgraduate medicine

authors： Niskanen WA

更新日期：1994-03-01 00:00:00

abstract：:The mere presence of uterine fibroids is not, since qua non, an indication for their surgical removal. Knowing when not to operate is probably more important for the physician than knowing when to operate. It is easy to fall into diagnostic and therapeutic traps when uterine fibroids are known to be present, especiall...

journal_title：Postgraduate medicine

authors： Russell KP

更新日期：1976-09-01 00:00:00

abstract：:Hoarseness indicates an abnormality at the level of the glottis. This symptom may result from either structural or physiologic disorders. The differential diagnosis is lengthy and includes both benign and malignant diseases. History taking and physical examination, particularly laryngeal visualization, provide key clu...

journal_title：Postgraduate medicine

authors： Dettelbach M,Eibling DE,Johnson JT

更新日期：1994-04-01 00:00:00

abstract：:This case report describes prolongation of a patient's prothrombin time and partial thromboplastin time possibly due to coadministration of warfarin and an overdose of an acetaminophen-propoxyphene combination analgesic. Patients receive warfarin for many indications, and concomitant use of an analgesic agent is commo...

journal_title：Postgraduate medicine

authors： Justice JL,Kline SS

更新日期：1988-04-01 00:00:00

abstract：:The role of reflux in the development of esophagitis, stricture, and Barrett's esophagus is well recognized. However, reflux is not an infrequent cause of atypical chest pain, chronic pulmonary disorders, and pharyngeal and laryngeal changes. Increased insight into the pathogenesis of reflux and the relationship betwe...

journal_title：Postgraduate medicine

authors： Barr LL

更新日期：1996-04-01 00:00:00

abstract：:Although coronary heart disease (CHD) remains the No. 1 cause of death in the United States, the CHD mortality rate has shown a recent decline. This has been attributed to lower fat consumption in the general population, with associated lower serum cholesterol levels. Thus, diet seems to be an important factor in cont...

journal_title：Postgraduate medicine

authors： Fletcher DJ,Rogers DA

更新日期：1985-04-01 00:00:00

abstract：:Beta-blockers (beta-blockers) have demonstrated their value across the cardiovascular disease spectrum. Beta-blockers effectively lower blood pressure in patients with hypertension and provide symptomatic or mortality benefits in patients with heart failure and in post-myocardial infarction patients. However, despite ...

journal_title：Postgraduate medicine

authors： Kountz DS

更新日期：2009-01-01 00:00:00

abstract：:Many patients who require evaluation for coronary artery disease are unable to undergo exercise stress testing because of physiologic or psychological limitations. Drs Vacek and Baldwin describe three alternative methods for assessment of cardiac function in these patients, all of which have high levels of diagnostic ...

journal_title：Postgraduate medicine

authors： Vacek JL,Baldwin T

更新日期：1989-09-15 00:00:00

abstract：:Serum electrolyte levels by themselves may be difficult to interpret. For example, an abnormal serum potassium concentration cannot be understood without taking into account the patient's history, other serum electrolyte values, and possibly results of other laboratory tests. Knowledge of the principles of serum elect...

journal_title：Postgraduate medicine

authors： Kapsner CO,Tzamaloukas AH

更新日期：1991-12-01 00:00:00

abstract：:Solid organ transplantation is now the standard of care for end-stage organ failure, and primary care physicians are frequently involved in the follow-up care of transplant recipients. New-onset diabetes mellitus after solid organ transplantation (NODAT) has emerged as an increasingly important determinant of outcomes...

journal_title：Postgraduate medicine

authors： Reynolds LR,Tannock LR

更新日期：2008-07-01 00:00:00

abstract：:Lactose intolerance is a common condition that can cause nonspecific gastrointestinal symptoms. A reliable diagnosis cannot be made on the basis of the patient's history. The breath hydrogen test is simple, noninvasive, accurate, and inexpensive and is the diagnostic method of choice. In addition to traditional dietar...

journal_title：Postgraduate medicine

authors： Montes RG,Perman JA

更新日期：1991-06-01 00:00:00

abstract：:Overuse syndrome and peripheral nerve entrapment syndromes arise in work situations in which the body is stressed beyond its limits by cumulative, repetitive trauma. These syndromes arise in some nonwork situations as well. When such an injury occurs, prompt diagnosis, treatment, and retraining aid in returning the em...

journal_title：Postgraduate medicine

authors： Mandel S

更新日期：1987-11-01 00:00:00

abstract：:In a series of 123 children with disorders of defecation, constipation was the main problem in 89 and fecal incontinence in 34. All but three of the latter also had constipation. The principal physical findings were abdominal protuberance with palpable stool in the bowel and the presence of a fecal mass in the rectal ...

journal_title：Postgraduate medicine

authors： Liebman WM

更新日期：1979-08-01 00:00:00

abstract：:The use of topical tretinoin (Retin-A) for comedonal lesions, benzoyl peroxide for inflamed papules and pustules, and topical or oral antibiotics for more severe or widespread disease gives excellent results for the majority of patients with acne. At present, oral isotretinoin (13-cis-retinoic acid) (Accutane) should ...

journal_title：Postgraduate medicine

authors： Greer KE

更新日期：1985-05-01 00:00:00

abstract：:Inflammatory bowel disease (IBD) is difficult to diagnose, and differentiating between ulcerative colitis (UC) and Crohn's disease (CD) can be challenging. Overlapping symptoms of UC and CD often delay diagnosis, despite availability of endoscopic, radiologic, and histologic tools. This delay in diagnosis is quite com...

journal_title：Postgraduate medicine

authors： Arai R

更新日期：2010-07-01 00:00:00

abstract：:The tools and methods of epidemiology, particularly the clinical trial, help guide the clinical practice of medicine. Dr Gorelick reviews the results of major clinical trials for prevention of transient cerebral ischemia and atherothrombotic stroke and assesses the effect of these findings on treatment. ...

journal_title：Postgraduate medicine

authors： Gorelick PB

更新日期：1989-12-01 00:00:00

abstract：:Findings from 441 patient evaluations performed at the Taste and Smell Clinic of the Connecticut Chemosensory Clinical Research Center are presented. Taste and smell dysfunction was the chief complaint in all patients. The diagnostic approach included tests of taste and smell function; history taking; physical, neurol...

journal_title：Postgraduate medicine

authors： Goodspeed RB,Gent JF,Catalanotto FA

更新日期：1987-01-01 00:00:00

abstract：:Although chronic hepatitis B is a relatively common disease that may have a serious outcome, the outlook is by no means uniformly poor. Alpha interferon therapy may be helpful in up to one third of patients who have hepatitis B e antigen in serum and elevated serum aminotransferase levels. New drugs that may have even...

journal_title：Postgraduate medicine

authors： Di Bisceglie AM

更新日期：1995-07-01 00:00:00

abstract：:Contrary to long-standing mores, what goes on in the person's home is not always sacred. When family relationships break down and family members deal violently with various stresses and problems, intervention is in order. Certain changes in societal attitudes would help prevent the problem. Physicians-alone or working...

journal_title：Postgraduate medicine

authors： Pelton CL

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND:Binge eating disorder (BED) is now a formal diagnosis in the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5). However, post-DSM-5 patient profiles and viewpoints on BED diagnosis and treatment remain unclear. This study used a focus group methodology to examine demographic and cl...

journal_title：Postgraduate medicine

authors： Herman BK,Safikhani S,Hengerer D,Atkins N Jr,Kim A,Cassidy D,Babcock T,Agus S,Lenderking WR

更新日期：2014-09-01 00:00:00

abstract：:Objectives: The commonest types of peripheral neuropathy in the context of Coeliac Disease (CD) and gluten sensitivity (GS) are length-dependent symmetrical sensorimotor neuropathies and sensory ganglionopathies. In patients with such neuropathy, (gluten neuropathy), peripheral neuropathic pain is prevalent suggesting...

journal_title：Postgraduate medicine

authors： Zis P,Sarrigiannis PG,Rao DG,Sanders DS,Hadjivassiliou M

更新日期：2019-09-01 00:00:00

abstract：:Infectious diseases in the institutionalized elderly are emerging as 1 of the major issues challenging physicians treating adult patients. The most common syndromes encountered are nursing home-acquired pneumonia, urinary tract infections, and skin and soft tissue infections. As a complicating factor, immunocompromise...

journal_title：Postgraduate medicine

authors： Bonomo RA

更新日期：2001-02-01 00:00:00

abstract：:The concurrent use of opioids, benzodiazepines (BZDs), and/or alcohol poses a formidable challenge for clinicians who manage chronic pain. While the escalating use of opioid analgesics for the treatment of chronic pain and the concomitant rise in opioid-related abuse and misuse are widely recognized trends, the contri...

journal_title：Postgraduate medicine

authors： Gudin JA,Mogali S,Jones JD,Comer SD

更新日期：2013-07-01 00:00:00

abstract：:Elderly patients should be evaluated closely before surgery. Problems commonly found in these patients (ie, hypertension, diabetes, and cardiac and pulmonary disease) should be sought with special care and treated before surgery is undertaken. Also, wound healing may be compromised, drug clearance and metabolism impai...

journal_title：Postgraduate medicine

authors： Nolan TE

更新日期：1992-02-01 00:00:00

abstract：:In developed countries, prevalence is increasing of malignancy-related secondary lymphedema, usually resulting from lymph node resection or irradiation. Untreated lymphedema usually increases over time, and the physical and psychological sequelae in even mild cases demand appropriate diagnosis and treatment. Patients ...

journal_title：Postgraduate medicine

authors： Tunkel RS,Lachmann E

更新日期：1998-10-01 00:00:00

abstract：:In this article, Drs Kerr and Yan describe four cases--two handled the wrong way and two the right way--to help you frame a set of criteria that will work for you in suspecting, testing for, diagnosing, and treating pulmonary embolism in ambulatory patients. In addition, Dr Kerr uses his legal expertise to provide sug...

journal_title：Postgraduate medicine

authors： Kerr CP,Yan L

更新日期：1992-05-15 00:00:00

abstract：:Catecholamine stimulation increases the heart rate and the force of cardiac contraction. Cardiac output then increases, with a decrease occurring in total peripheral resistance due to smooth muscle dilation in the vascular beds of the muscle and heart, though there is constriction of the skin and viscera; this leads t...

journal_title：Postgraduate medicine

authors： Fox KM

更新日期：1988-02-29 00:00:00

abstract：:Although a great deal of investigation has led to some novel approaches in treating primary sclerosing cholangitis (PSC) and primary biliary cirrhosis (PBC), no method has been proven to definitively alter the long-term outcome of either disease. In addition, many of the medical regimens reviewed in this article have ...

journal_title：Postgraduate medicine

authors： Fennerty MB

更新日期：1993-11-01 00:00:00

abstract：:In the past decade, significant progress has been made in the understanding and treatment of Alzheimer's disease. Modest success has been achieved using new drugs in treatment of mild symptoms of the disease. Vitamin E, estrogen, and NSAIDs may slow the progression of Alzheimer's disease, but their routine use is not ...

journal_title：Postgraduate medicine

authors： Burke JR,Morgenlander JC

更新日期：1999-10-15 00:00:00

abstract：:Asthma is treated by avoiding the precipitants of symptoms, by a trial of hyposensitization (immunotherapy) if the precipitant cannot be avoided, and principally by pharmacologic therapy. Acute attacks have been most widely treated with epinephrine, but adrenergic aerosol bronchodilators and aminophylline are being us...

journal_title：Postgraduate medicine

authors： Ellis EF

更新日期：1976-04-01 00:00:00