Clinical significance of tartrate-resistant acid phosphatase type-5 expression in human gastric cancer.

abstract：:We report a case of secondary chondrosarcoma arising in the ilium showing spontaneous regression after frequent local tumor recurrences followed by multiple surgeries of marginal or intralesional excision. The patient was a 16-year-old boy who had been diagnosed as having multiple exostosis from 9 years of age. He exp...

journal_title：Anticancer research

authors： Nakamura S,Kusuzaki K,Murata H,Takeshita H,Hirata M,Hashiguchi S,Hirasawa Y

更新日期：2000-09-01 00:00:00

abstract：:Angiogenesis is critical for tumor growth and inflammation. Shiunko is a Chinese herbal ointment used for the treatment of burns in Japan. Its main ingredient is the root of Lithospermum erythrorhizon, which had been used for treating tumors and inflammation in China since the 5th century. We report here that shikonin...

journal_title：Anticancer research

authors： Hisa T,Kimura Y,Takada K,Suzuki F,Takigawa M

更新日期：1998-03-01 00:00:00

abstract：:Pyrimidine nucleoside phosphorylase (PyNPase) is an enzyme which converts 5'-deoxy-5-fluorouridine (5'-DFUR) to 5-fluorouracil (5-FU), and is induced by various cytokines in tumor cells. We evaluated a combination of 5'-DFUR and lentinan which is widely used as a biological response modifier (BRM), to verify antitumor...

journal_title：Anticancer research

authors： Ogawa T,Ohwada S,Sato Y,Izumi M,Nakamura S,Takeyoshi I,Kawashima Y,Ohya T,Koyama T,Morishita Y

更新日期：1999-01-01 00:00:00

abstract：:One of the biggest challenges in health care is the fight against tumors. Some phenothiazines have antitumor activity on HEp-2 tumor cells. In this study, we tested the antitumor effects of three series such as 10-nonsubstituted phenothiazines, 10-[n-(phthalimido)alkyl]-2-substituted-10H-phenothiazines and 1-(chloroet...

journal_title：Anticancer research

authors： Nagy S,Argyelan G,Molnár J,Kawase M,Motohashi N

更新日期：1996-07-01 00:00:00

abstract：:The centrifugal spreading of multicellular aggregates from a DMH induced colon adenocarcinoma cell line from rats was observed in vitro. Various concentrations of pentagastrin were added to the culture medium. Controls included medium alone or culture medium containing different concentrations of either NH4OH or NaOH ...

journal_title：Anticancer research

authors： Schallier D,Van der Elst J,De Neve W,Storme G

更新日期：1986-03-01 00:00:00

abstract：UNLABELLED:Reduced serum-zinc concentrations are well known as typical laboratory characteristics in advanced head and neck cancer. Our aim was to follow the development of this phenomenon during the disease. PATIENTS AND METHODS:A total of 21 patients were included in this pilot-study (1 female, 20 male). The median ...

journal_title：Anticancer research

authors： Büntzel J,Bruns F,Glatzel M,Garayev A,Mücke R,Kisters K,Schäfer U,Schönekaes K,Micke O

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND/AIM:Autophagy can be either tumor promotive or suppressive. We previously identified an autophagy-inducing activity in the 30-100 kDa fraction of areca-nut-extract (ANE 30-100K) and showed that several tumor cells subjected to chronic ANE 30-100K stimulation (CAS) exhibited higher resistance against stressed...

journal_title：Anticancer research

authors： Chiu CT,Liu SY,Yen CY,Liu BY,Sun ZY,Wu CY,Deng JL,Liu YC,Lin MH

更新日期：2020-01-01 00:00:00

abstract：UNLABELLED:Distant metastases to the oral cavity, the face or facial skeleton are rare and/in are usually found in such locations at a late stage of the malignancy. In the majority of cases, the malignancy is already known at the time of admission. However, a distant metastasis as the first sign of a cancer developing ...

journal_title：Anticancer research

authors： Friedrich RE,Abadi M

更新日期：2010-05-01 00:00:00

abstract：:To evaluate further the chemopreventive role of motherwort (Leonurus sibiricus L; MW) in lesions of the mammary gland and uterus of GR/A mice, the effects on these lesions of the adsorbed (MW1) and unadsorbed (MW2) fractions of MW separated by ion-exchange resins were studied. The incidence of palpable mammary tumours...

journal_title：Anticancer research

authors： Nagasawa H,Inatomi H,Suzuki M,Mori T

更新日期：1992-01-01 00:00:00

abstract：:D-Penicillamine, a structural analog of cysteine, has the ability to chelate metal ions and reacts with cysteine. We have shown earlier that D-Penicillamin is a potential inhibitor of tat-mediated transactivation of HIV-1-LTR (14) and possesses anti-HIV-1 activity (23). Following this approach, we evaluated the anti-t...

journal_title：Anticancer research

authors： Demirhan I,Chandra A,Sarin PS,Hasselmayer O,Hofmann D,Chandra P

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND/AIM:We have previously reported that alternate-day S-1 had comparable effects and milder adverse events than the respective consecutive-day regimen in head and neck cancer (HNC) patients. The aim of this study was to investigate the anticancer effects of both regimens and underlying mechanisms in vitro. MAT...

journal_title：Anticancer research

authors： Moro Y,Kogashiwa Y,Sakurai H,Takahashi R,Kimura T,Hirasaki M,Matsumoto Y,Sugasawa M,Kohno N

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND/AIM:The oxazaphosphorines, ifosfamide and cyclophosphamide, represent a class of alkylating agents. The aim of the present in vitro study was to compare antileukemic activity of 4-hydroperoxyifosfamide (4-OOH-IF) and 4-hydroperoxycyclophosphamide (4-OOH-CP). MATERIALS AND METHODS:The experiments were perfor...

journal_title：Anticancer research

authors： Opydo-Chanek M,Śladowska K,Blicharski K,Mikeš J,Fedoročko P,Niemeyer U,Mazur L

更新日期：2017-11-01 00:00:00

abstract：:Adenomatoid odontogenic tumour (AOT) is a benign tumour of odontogenic origin. The differential diagnosis of AOT is crucial in terms of surgical management. The 23-year old male patient presented in this case study was referred to the maxillofacial surgery clinic due to the incidental radiological finding of a large o...

journal_title：Anticancer research

authors： Friedrich RE,Zustin J,Scheuer HA

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:We hypothesize that dendritic cells (DCs) can process antigens from autologous melanoma apoptotic bodies (MABs) and induce effector T cells in melanoma patients. MATERIALS AND METHODS:Peripheral blood mononuclear cells were obtained from three stage IV melanoma patients and adherent cells were cultured in c...

journal_title：Anticancer research

authors： Chang JW,Peng M,Vaquerano JE,Zhou YM,Clinton RA,Hyun WC,Giedlin MA,Leong SP

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND/AIM:Patients with obstructive jaundice due to cancer of the pancreatic head often undergo preoperative endoscopic biliary drainage (EBD). The aim of the study was to evaluate the long-term impact of preoperative EBD following pancreaticoduodenectomy (PD) for pancreatic ductal adenocarcinoma. PATIENTS AND ME...

journal_title：Anticancer research

authors： Furukawa K,Shiba H,Shirai Y,Horiuchi T,Iwase R,Haruki K,Fujiwara Y,Misawa T,Yanaga K

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Active hexose-correlated compound (AHCC) is an extract of a basidiomycete mushroom that enhances the therapeutic effects and reduces the side-effects of chemotherapy. Our previous studies demonstrated that heat-shock protein 27 (HSP27) was involved in gemcitabine-resistance of pancreatic cancer cells and it ...

journal_title：Anticancer research

authors： Tokunaga M,Baron B,Kitagawa T,Tokuda K,Kuramitsu Y

更新日期：2015-11-01 00:00:00

abstract：:In a retrospective analysis we investigated 59 children with de novo acute lymphoblastic leukemia (ALL) and 28 patients with relapsed ALL for the expression of cyclin D1 using RT-PCR. In addition, the relationships of cyclin D1 to the retinoblastoma tumor suppressor gene and the Ki-67-expression were analyzed. Cyclin ...

journal_title：Anticancer research

authors： Sauerbrey A,Häfer R,Zintl F,Volm M

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND/AIM:It is unknown whether hypoxia regulates aurora kinase A (AURKA), a serine/threonine kinase, in neuroblastoma to stimulate cell growth or migration. We sought to determine whether AURKA mediates hypoxia-induced regulation of neuroblastoma tumorigenicity. MATERIALS AND METHODS:Human neuroblastoma BE(2)-C ...

journal_title：Anticancer research

authors： Romain CV,Paul P,Lee S,Qiao J,Chung DH

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND/AIM:Despite numerous studies, the etiology of chronic lymphocytic leukemia (CLL) remains unknown. A hypothesis of autoantigen stimulation in leukemic clone selection might explain 'stereotypy' of B-cell receptors. In healthy cells, cofilin-1 (CFL1) has multiple functions. Its role was described in several ma...

journal_title：Anticancer research

authors： Karp M,Karczmarczyk A,Bojarska-Junak A,Purkot J,Chojnacki M,ZajĄc M,Korpysz M,Tomczak W,Hus M,Morawska M,Giannopoulos K

更新日期：2020-11-01 00:00:00

abstract：:MDL 103,323, an enclomiphene analog, was tested for binding to the estrogen receptor, inhibition of human tumor xenografts and prevention of carcinogen-induced mammary tumors. MDL 103,323 had 5-6 fold greater affinity for the human estrogen receptor than did either tamoxifen or enclomiphene. Consistent with enhanced b...

journal_title：Anticancer research

authors： Bitonti AJ,Baumann RJ,Bush TL,Cashman EA,Wright CL,Prakash NJ

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND/AIM:Previous studies have shown discrepancies between patient's desired and actual death place. As planning of family support and involvement of palliative home care teams seem to improve the chance to meet patients preferences, geographical availability of specialized palliative home care could influence pl...

journal_title：Anticancer research

authors： Nilsson J,Axelsson B,Holgersson G,Carlsson T,Bergqvist M,Bergstrom S

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:The extent of radiogenic damage in salivary gland (SG) tissue depends on the radiation dose (RD), the fractionation (FN) and the localization of SG in the radiation field (RF). While the functional restriction and the radiogenic SG tissue damage are well documented using histomorphological, electron-microscop...

journal_title：Anticancer research

authors： Bartel-Friedrich S,Friedrich RE,Lautenschläger C,Holzhausen HJ,Moll R

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Periacetabular reconstruction after malignant bone tumor resection to preserve limb function is extremely challenging. The optimal reconstruction method has not yet received consensus and the functional outcomes still remain unsatisfactory. CASE REPORT:A thirteen-year-old girl who was suffering from acetabu...

journal_title：Anticancer research

authors： Kubo T,Sugita T,Shimose S,Tanaka H,Nobuto H,Tanaka K,Ochi M

更新日期：2004-05-01 00:00:00

abstract：:The development and maintenance of testicular interstitial cell (IC) tumors under the conditions of low LH levels were examined in aged Fischer 344 rats, and the enzyme activities for androgen synthesis in the tumors were estimated. Sixty-week old rats received injections of an LH-RH agonist (LH-RHa) for 28 weeks or w...

journal_title：Anticancer research

authors： Chatani F,Nonoyama T,Sudo K,Miyajima H,Takeyama M,Takatsuka D,Mori H,Matsumoto K

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Warthin-like mucoepidermoid carcinoma is a newly recognized rare entity and could be misdiagnosed as a benign Warthin tumor. We report such a case of a 36-year-old male who presented with a left parotid gland mass. CASE REPORT:Fine-needle aspiration showed features suggestive of Warthin tumor. Following par...

journal_title：Anticancer research

authors： Zhang D,Liao X,Tang Y,Meyer RG,VAN Dyke DL,Liu X,Islam MN,Lai J

更新日期：2019-06-01 00:00:00

abstract：UNLABELLED:Gastric carcinoma occurs in response to chronic inflammation of gastric mucosa infected with Helicobacter pylori. It is not known how cytokines affect the growth and progression of gastric carcinoma. MATERIALS AND METHODS:We measured tissue concentrations of the proinflammatory cytokines interleukin (IL)-1b...

journal_title：Anticancer research

authors： Kai H,Kitadai Y,Kodama M,Cho S,Kuroda T,Ito M,Tanaka S,Ohmoto Y,Chayama K

更新日期：2005-03-01 00:00:00

abstract：AIM:To elucidate the behavior of 1 phosphatidylinositol 4,5 bisphosphate (PIP2) 5 phosphatase (PIP2 5-Pase, EC 3.1.3.36) and 1 phosphatidylinositol 4 phosphate (PIP) 4-phosphatase (PIP 4-Pase) in cancer cells, the steady state activities of PIP2 5-Pase and PIP 4-Pase were determined in the particulate fractions of rat ...

journal_title：Anticancer research

authors： Yang H,Shen F,Weber G

更新日期：1999-11-01 00:00:00

abstract：:Non-small-cell lung cancer (NSCLC) ranks as a leading cause of cancer-related death globally. Brain metastases are a frequent complication of NSCLC, with 25-40% of patients developing brain metastases during the course of the disease, often within the first 2 years after diagnosis of the primary tumor. Improvements in...

journal_title：Anticancer research

authors： Dempke WC,Edvardsen K,Lu S,Reinmuth N,Reck M,Inoue A

更新日期：2015-11-01 00:00:00

abstract：:Bone-seeking radionuclides have been used to treat bone pain due to metastatic bone disease for over 40 years. More than 10 clinical studies using radiostrontium (Sr-89) have shown benefit in about 70-80% of patients having refractory bone pain from prostate, breast and other metastatic bone cancers, with minimal hema...

journal_title：Anticancer research

authors： Kim SI,Chen DC,Muggia FM

更新日期：1988-07-01 00:00:00

abstract：:The time course and characteristics of the tumor marker CASA (Cancer Associated Serum Antigen) during the menstrual cycle were analysed. We investigated whether hormonal influences in women and the score of this tumor marker ought to be considered in diagnosis. It could be demonstrated that CASA is not influenced by p...

journal_title：Anticancer research

authors： Meisel M,Römer T,Straube W

更新日期：1997-07-01 00:00:00