Newborn polymorphonuclear leukocyte aggregation: a study of physical properties and ultrastructure using chemotactic peptides.

abstract：:This study investigated the effects of intraventricular/periventricular blood on cerebral cAMP production and cortical cerebrovascular reactivity. Under halothane and N2O anesthesia, 3 mL of either autologous blood or artificial cerebrospinal fluid (CSF) were injected into the left caudate nucleus; volume was adequate...

journal_title：Pediatric research

authors： Pourcyrous M,Parfenova H,Shibata M,Bada HS,Korones SB,Leffler CW

更新日期：1997-09-01 00:00:00

abstract：:Several hours after an hypoxic-ischemic injury to the developing brain, hyperemia, then seizures, edema, and infarction can develop. The roles of nitric oxide (NO) synthesis and excitotoxin accumulation during these later phases of injury are not known. The time course of extracellular levels of amino acids within the...

journal_title：Pediatric research

authors： Tan WK,Williams CE,During MJ,Mallard CE,Gunning MI,Gunn AJ,Gluckman PD

更新日期：1996-05-01 00:00:00

abstract：:Periventricular leukomalacia (PVL), the major substrate of neurologic deficits in premature infants, is associated with reduced white matter volume. Using immunomarkers of axonal pathology [beta-amyloid precursor protein (beta-APP) and apoptotic marker fractin], we tested the hypothesis that widespread (diffuse) axona...

journal_title：Pediatric research

authors： Haynes RL,Billiards SS,Borenstein NS,Volpe JJ,Kinney HC

更新日期：2008-06-01 00:00:00

abstract：:The ontogeny of glutamine uptake by jejunal brush border membrane vesicles was studied in suckling and weanling rats and compared with the data obtained from previous studies done on adult rats in our laboratory. Glutamine uptake represented transport into the intravesicular space rather than mere binding into the mem...

journal_title：Pediatric research

authors： al-Mahroos FT,Bulus N,Abumrad N,Said H,Ghishan FK

更新日期：1990-05-01 00:00:00

abstract：:A new animal experimental model of human neuroblastoma is described. The model involves xenotransplantation of a poorly differentiated human neuroblastoma cell line (SH-SY5Y) to the subcutaneous tissue in the hind leg of nude rats (WAG mu/rnu). Injection of 20 million cells suspended in 0.2 mL of medium in each hind l...

journal_title：Pediatric research

authors： Wassberg E,Påhlman S,Westlin JE,Christofferson R

更新日期：1997-03-01 00:00:00

abstract：:Necrotizing enterocolitis (NEC) remains among the most common and devastating diseases in neonates. Despite advances in neonatal clinical care, specific treatment strategies and diagnostic modalities remain lacking. As a result, morbidity and mortality remain high. Improved understanding of the pathogenesis of NEC has...

journal_title：Pediatric research

authors： Shelby RD,Raab R,Besner GE,McElroy SJ

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Some of the health advantages of breast-fed as compared to formula-fed infants have been suggested to be due to metabolic programming effects resulting from early nutrition. METHODS:In a prospective double-blinded randomized trial, 160 infants <2 mo of age were randomized to experimental formula (EF) with a...

journal_title：Pediatric research

authors： Timby N,Lönnerdal B,Hernell O,Domellöf M

更新日期：2014-10-01 00:00:00

abstract：:This report deals with quantitative and qualitative investigations of alkaline phosphatase in two unrelated infants with the severe infantile form of hypophosphatasia. Both affected infants had no detectable leukocyte alkaline phosphatase activities and both sets of parents and one sibling tended to have low but varia...

journal_title：Pediatric research

authors： Gorodischer R,Davidson RG,Mosovich LL,Yaffe SJ

更新日期：1976-07-01 00:00:00

abstract：:Infantile Refsum's disease is characterized by high levels of phytanic acid and the absence of normal hepatic peroxisomes. We investigated the in vivo influence of phytol, a precursor of phytanic acid, on peroxisomes by both biochemical and morphological methods. Enhanced supply of phytol in the diet of adult mice cau...

journal_title：Pediatric research

authors： Van den Branden C,Vamecq J,Wybo I,Roels F

更新日期：1986-05-01 00:00:00

abstract：:Apoptosis of CD4+ and CD8+ T cells has been shown in peripheral blood mononuclear cells (PBMCs) from HIV-infected adults analyzed after overnight culture. Because cell death may be an artifact of in vitro culture, and because there is little information on apoptosis in pediatric HIV disease, we undertook a cross-secti...

journal_title：Pediatric research

authors： Cotton MF,Ikle DN,Rapaport EL,Marschner S,Tseng PO,Kurrle R,Finkel TH

更新日期：1997-11-01 00:00:00

abstract：:To localize fetal rabbit lung beta-adrenoreceptors before and after glucocorticoid treatment, light microscopic autoradiography was performed with the reversible radiolabeled beta-adrenergic antagonist, [3H]dihydroalprenolol, on day 26 of gestation. Autoradiograms of adult lung and fetal myocardium were also prepared....

journal_title：Pediatric research

authors： Barnes P,Jacobs M,Roberts JM

更新日期：1984-11-01 00:00:00

abstract：:The results of prior studies suggest that abnormalities of development and function of the fetal adrenal occur in pregnancies complicated by intrauterine fetal growth retardation (IUGR). In the present investigation, we sought to extend such studies by matching IUGR infants with normally grown infants of women in whom...

journal_title：Pediatric research

authors： Parker CR Jr,Buchina ES,Barefoot TK

更新日期：1994-06-01 00:00:00

abstract：:The head sizes of 38 patients, growth hormone (GH) deficient following craniospinal (n = 26) or cranial irradiation (n = 12), have been assessed before (n = 38) and on completion of GH therapy (n = 15) or at the end of a similar period of observation without GH (n = 7). These results were compared to the change in hea...

journal_title：Pediatric research

authors： Clayton PE,Shalet SM,Price DA,Surtees RA,Pearson D

更新日期：1987-10-01 00:00:00

abstract：:In order to study the neonatal microcirculation, the capillary hemodynamics in skin was investigated in 43 full-term infants 2-7 days after birth. The nailfold capillaries of the thumb were visualized by means of television microscopy and the capillary blood cell velocity (CBV) was videophotometrically quantified in 1...

journal_title：Pediatric research

authors： Norman M,Herin P,Fagrell B,Zetterström R

更新日期：1988-06-01 00:00:00

abstract：:The effect of alpha-adrenergic blockade by phentolamine on the pulmonary vascular response to dopamine was studied in chronically prepared newborn lambs. Dopamine was administered at doses of 2.7 micrograms . kg-1 . min-1, 27 micrograms . kg-1 . min-1 and 270 micrograms . kg-1 . min-1 with and without alpha-adrenergic...

journal_title：Pediatric research

authors： Williams BJ,Drummond WH

更新日期：1983-06-01 00:00:00

abstract：:Vagal responsivity to orogastric stimulation is necessary for gastrointestinal function and may reflect autonomic regulation. Our study evaluated vagal responsivity during gavage feeding as an index of preterm clinical status. Vagal and behavioral responsivity of 26 preterm infants during gavage feeding was measured. ...

journal_title：Pediatric research

authors： DiPietro JA,Porges SW

更新日期：1991-03-01 00:00:00

abstract：BACKGROUND:Animal models have shown that insulin-like growth factor I (IGF-I) may mediate protein-induced kidney growth. Our aim was to analyze the effect of IGF-I on protein-induced kidney growth in healthy infants. METHODS:This is a secondary analysis of a randomized trial that compared growth of infants fed with a ...

journal_title：Pediatric research

authors： Luque V,Escribano J,Grote V,Ferre N,Koletzko B,Gruszfeld D,Socha P,Langhendries JP,Goyens P,Closa-Monasterolo R,European Childhood Obesity Project.

更新日期：2013-08-01 00:00:00

abstract：:Establishment of Helicobacter pylori infection as an etiologic agent of peptic ulcer disease and other gastric pathologies marked a revolution in gastroenterology which spurred an enormous interest in gastric physiology and immunology research. The association was soon also demonstrated in children as well. Applicatio...

journal_title：Pediatric research

authors： Blanchard TG,Czinn SJ

更新日期：2017-01-01 00:00:00

abstract：:In spontaneously breathing newborn lambs, alveolar hypoxia increases lung microvascular pressure, which causes lung lymph flow to increase and the concentration of protein in lymph to decrease. To see if this response derives from hypoxia itself rather than from the change in breathing pattern that occurs during hypox...

journal_title：Pediatric research

authors： Hansen TN,Haberkern CM,Hazinski TA,Bland RD

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:Cardiovascular (CV) complications are the most significant cause of mortality in adults with Cushing disease (CD); little is known about CV risk factors in children with CD. Measurement of lipoprotein particles by nuclear magnetic resonance (NMR) spectroscopy is a novel technology to assess CV risk. The obje...

journal_title：Pediatric research

authors： Makri A,Cheung A,Sinaii N,Remaley AT,Sampson M,Keil M,Belyavskaya E,Lyssikatos C,De La Luz Sierra M,Stratakis CA,Lodish M

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Volatile organic compounds (VOCs) are hydrocarbons that originate within different healthy and diseased tissues. VOCs can be secreted into the circulation and then excreted in the urine and faeces. In the lungs, VOCs are locally produced and can be detected in exhaled breath. VOCs can be identified using non...

journal_title：Pediatric research

authors： Wright H,Bannaga AS,Iriarte R,Mahmoud M,Arasaradnam RP

更新日期：2020-03-02 00:00:00

abstract：:Acute postasphyxial encephalopathy around the time of birth remains a major cause of death and disability. The possibility that hypothermia may be able to prevent or lessen asphyxial brain injury is a "dream revisited". In this review, a historical perspective is provided from the first reported use of therapeutic hyp...

journal_title：Pediatric research

authors： Gunn AJ,Laptook AR,Robertson NJ,Barks JD,Thoresen M,Wassink G,Bennet L

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Near-infrared spectroscopy is used in the assessment of regional splanchnic oxygen saturation (rsSO2), but solid reference values are scarce. We aimed to establish reference values of rsSO2 for preterm infants during the first week after birth, both crude and modeled based on predictors. METHODS:We included...

journal_title：Pediatric research

authors： van der Heide M,Dotinga BM,Stewart RE,Kalteren WS,Hulscher JBF,Reijneveld SA,Bos AF,Kooi EMW

更新日期：2021-01-27 00:00:00

abstract：:This study determines the inotropic effects of prostaglandin D2 (PGD2) and prostaglandin E1 (PGE1) in the isolated, arterial perfused newborn (NB) and adult (A) rabbit heart. Significant positive inotropism of PGD2 was observed at all concentrations studied (1 X 10(-17) to 1 X 10(-7) M) in the two age groups; the effe...

journal_title：Pediatric research

authors： Uemura S,Nakanishi T,Matsuoka S,Friedman WF,Jarmakani JM

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:Staphylococcus aureus is the leading cause of skin and soft tissue infections (SSTIs). To develop interventions to prevent recurrent infections, household attributes and individual practices influencing S. aureus colonization must be discerned. METHODS:Households of healthy children with methicillin-resista...

journal_title：Pediatric research

authors： Mork RL,Hogan PG,Muenks CE,Boyle MG,Thompson RM,Morelli JJ,Sullivan ML,Gehlert SJ,Ross DG,Yn A,Bubeck Wardenburg J,Rzhetsky A,Burnham CD,Fritz SA

更新日期：2018-11-01 00:00:00

abstract：:Whether severe hypoglycemia alone or in combination with hyperketonemia might cause deterioration of cardiac function has been controversial. Therefore, the influence of acute hypoglycemia (mean 33 mg/dL) with and without hyperketonemia (mean 1.3 and 3.3 mM) on cardiac function, substrate utilization, and myocardial h...

journal_title：Pediatric research

authors： Breuer J,Chung KJ,Pesonen E,Haas RH,Guth BD,Sahn DJ,Hesselink JR

更新日期：1989-12-01 00:00:00

abstract：:A recently introduced test measures the concentration of transferrin receptor (TfR) in serum, which increases shortly after the onset of iron deficiency. In adults this increase reflects the degree to which tissue iron availability is impaired. We developed a fluoroimmunoassay to quantify TfR. The purpose of this stud...

journal_title：Pediatric research

authors： Kivivuori SM,Anttila R,Viinikka L,Pesonen K,Siimes MA

更新日期：1993-09-01 00:00:00

abstract：:The global burden of kidney disease is increasing, and several etiologies first begin in childhood. Risk factors for pediatric kidney disease are common in Africa, but data regarding its prevalence are lacking. We completed a systematic review of community-based studies describing the prevalence of proteinuria, hematu...

journal_title：Pediatric research

authors： Kayange NM,Smart LR,Tallman JE,Chu EY,Fitzgerald DW,Pain KJ,Peck RN

更新日期：2015-02-01 00:00:00

abstract：BACKGROUND:Protein intake may modulate cardiac structure and function in pathological conditions, but there is a lack of knowledge on potential effects in healthy infants. METHODS:Secondary analysis of an ongoing randomized clinical trial comparing two groups of infants receiving a higher (HP) or lower (LP) protein co...

journal_title：Pediatric research

authors： Collell R,Closa-Monasterolo R,Ferré N,Luque V,Koletzko B,Grote V,Janas R,Verduci E,Escribano J

更新日期：2016-06-01 00:00:00

abstract：:Factors affecting bone turnover in premature infants are not entirely clear but certainly are different from those influencing bones of adults and children. To identify fetal and maternal factors that might influence bone turnover, we prospectively studied 50 infants (30 preterm and 20 full-term) born at Ain Shams Uni...

journal_title：Pediatric research

authors： Aly H,Moustafa MF,Amer HA,Hassanein S,Keeves C,Patel K

更新日期：2005-05-01 00:00:00