Myelomalacia and hypoglycorrhachia in malignant atrophic papulosis.

abstract：OBJECTIVE:To determine the potential of detection in CSF of specific Borrelia burgdorferi antigen, OspA, as a marker of infection in neurologic Lyme disease and compare this with the detection of antibody. DESIGN:CSF from 83 neurologic patients in an area highly endemic for Lyme disease was examined prospectively for ...

journal_title：Neurology

authors： Coyle PK,Schutzer SE,Deng Z,Krupp LB,Belman AL,Benach JL,Luft BJ

更新日期：1995-11-01 00:00:00

abstract：OBJECTIVE:To assess frontal lobe functions of subjects with age-associated memory impairment (AAMI) and to examine whether performance on neuropsychological tests is correlated with the volume of the frontal lobes in magnetic resonance imaging. DESIGN:Cross-sectional two-group comparison. SETTING:The Memory Research ...

journal_title：Neurology

authors： Hänninen T,Hallikainen M,Koivisto K,Partanen K,Laakso MP,Riekkinen PJ Sr,Soininen H

更新日期：1997-01-01 00:00:00

abstract：:We used single-photon emission computed tomography (SPECT) to study postictal cerebral blood flow (CBF) in 51 patients with temporal lobe epilepsy. There were 78 seizures studied, 77 by early postictal injection of Tc-99m HMPAO (delay from seizure onset = 4.3 +/- 4.5 min) and one by ictal injection. Increased focal te...

journal_title：Neurology

authors： Rowe CC,Berkovic SF,Austin MC,McKay WJ,Bladin PF

更新日期：1991-07-01 00:00:00

abstract：:Of 101 patients with benign intracranial hypertension not related to vasculitis, neck stiffness occurred in 31, tinnitus in 27, distal extremity paresthesias in 22, joint pains in 13, low back pain in 5, and gait "ataxia" in 4. Symptoms resolved promptly upon lowering the intracranial pressure by lumbar puncture, and ...

journal_title：Neurology

authors： Round R,Keane JR

更新日期：1988-09-01 00:00:00

abstract：:Recurrent stroke is a major public health concern and new treatment strategies are needed. While modulation of the renin angiotensin aldosterone system (RAAS) has proven effective in reducing recurrent cardiac events, its role in preventing recurrent cerebrovascular events remains unclear. RAAS is both a circulating a...

journal_title：Neurology

authors： Sokol SI,Portnay EL,Curtis JP,Nelson MA,Hebert PR,Setaro JF,Foody JM

更新日期：2004-07-27 00:00:00

abstract：:Systematic screening of many compounds in animal models led to identification of the established antiepileptic drugs (AEDs). By contrast, the newer AEDs were specifically designed to enhance an inhibitory process or to inhibit a specific excitatory pathway. However, it was later discovered that some of the designed dr...

journal_title：Neurology

authors： Moshé SL

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:Analysis of twins with epilepsy to explore the genetic architecture of specific epilepsies, to evaluate the applicability of the 2010 International League Against Epilepsy (ILAE) organization of epilepsy syndromes, and to integrate molecular genetics with phenotypic analyses. METHODS:A total of 558 twin pair...

journal_title：Neurology

authors： Vadlamudi L,Milne RL,Lawrence K,Heron SE,Eckhaus J,Keay D,Connellan M,Torn-Broers Y,Howell RA,Mulley JC,Scheffer IE,Dibbens LM,Hopper JL,Berkovic SF

更新日期：2014-09-16 00:00:00

abstract：:Neurogenic left ventricular dysfunction is a recognized complication of subarachnoid hemorrhage, but this condition has not been reported after seizure activity. The authors present two cases of neurogenic stunned myocardium after convulsive seizures, suggesting that ictal activity can lead to sympathetically mediated...

journal_title：Neurology

authors： Chin PS,Branch KR,Becker KJ

更新日期：2005-06-14 00:00:00

abstract：OBJECTIVE:Clinical trials of fetal neural tissue transplantation for Huntington disease (HD) have been conducted with variable clinical results. However, no long-term analysis of graft survival and integration has been published. Here, we report the pathologic findings in two patients with HD who died 74 and 79 months ...

journal_title：Neurology

authors： Keene CD,Sonnen JA,Swanson PD,Kopyov O,Leverenz JB,Bird TD,Montine TJ

更新日期：2007-06-12 00:00:00

abstract：BACKGROUND:In the late 19th century, a man with a psychogenic movement disorder was evaluated by many of the Philadelphia neurologists associated with Silas Weir Mitchell. In 1885, prior to the development of movie cameras or projectors, the patient was photographed by pioneering photographer Eadweard Muybridge, in col...

journal_title：Neurology

authors： Lanska DJ

更新日期：2015-01-27 00:00:00

abstract：:We report a patient with striatonigral degeneration in whom T2-weighted MRI imaging revealed low signal and atrophy in the putamen. Neuropathologic studies confirmed putaminal atrophy and iron deposition in the MRI low signal regions. ...

journal_title：Neurology

authors： O'Brien C,Sung JH,McGeachie RE,Lee MC

更新日期：1990-04-01 00:00:00

abstract：OBJECTIVE:To develop evidence-based recommendations for complementary and alternative medicine (CAM) in multiple sclerosis (MS). METHODS:We searched the literature (1970-March 2011; March 2011-September 2013 MEDLINE search), classified articles, and linked recommendations to evidence. RESULTS AND RECOMMENDATIONS:Clin...

journal_title：Neurology

authors： Yadav V,Bever C Jr,Bowen J,Bowling A,Weinstock-Guttman B,Cameron M,Bourdette D,Gronseth GS,Narayanaswami P

更新日期：2014-03-25 00:00:00

abstract：OBJECTIVES:To assess the association of established multiple sclerosis (MS) risk variants in 3,254 African Americans (1,162 cases and 2,092 controls). METHODS:Human leukocyte antigen (HLA)-DRB1, HLA-DQB1, and HLA-A alleles were typed by molecular techniques. Single nucleotide polymorphism (SNP) genotyping was conducte...

journal_title：Neurology

authors： Isobe N,Gourraud PA,Harbo HF,Caillier SJ,Santaniello A,Khankhanian P,Maiers M,Spellman S,Cereb N,Yang S,Pando MJ,Piccio L,Cross AH,De Jager PL,Cree BA,Hauser SL,Oksenberg JR

更新日期：2013-07-16 00:00:00

abstract：:We investigated the role of ceruloplasmin in the antioxidative process in the brain in a patient with hereditary ceruloplasmin deficiency (HCD). Immunohistochemistry revealed an accumulation of Nepsilon-(carboxymethyl) lysine (CML) in basal ganglia of the HCD brain. In vitro study disclosed that ceruloplasmin inhibite...

journal_title：Neurology

authors： Tajima K,Kawanami T,Nagai R,Horiuchi S,Kato T

更新日期：1999-08-11 00:00:00

abstract：OBJECTIVE:To assess whether faster cognitive decline in elders without dementia is associated with decreased risk of cancer mortality. METHODS:In this population-based, prospective study of 2,627 people without dementia aged 65 years and older (Neurological Disorders in Central Spain), a 37-item version of the Mini-Me...

journal_title：Neurology

authors： Benito-León J,Romero JP,Louis ED,Bermejo-Pareja F

更新日期：2014-04-22 00:00:00

abstract：OBJECTIVE:To evaluate the impact of early blood pressure (BP) changes on diffusion-weighted imaging (DWI) lesion evolution and clinical outcome in patients with stroke treated with IV tissue plasminogen activator (tPA). METHODS:We prospectively evaluated 80 patients with stroke with a documented middle cerebral artery...

journal_title：Neurology

authors： Delgado-Mederos R,Ribo M,Rovira A,Rubiera M,Munuera J,Santamarina E,Delgado P,Maisterra O,Alvarez-Sabin J,Molina CA

更新日期：2008-08-19 00:00:00

abstract：:We studied the scalp distribution of auditory event-related potentials (P300), using simultaneously a cephalic (linked ears) and a noncephalic (balanced sternovertebra) reference. The recordings with noncephalic reference showed that infrequent, attended auditory stimuli evoke a negative bitemporal component (N300) as...

journal_title：Neurology

authors： Neshige R,Lüders H

更新日期：1988-11-01 00:00:00

abstract：OBJECTIVE:To provide a comprehensive understanding of APOE ε4 effects across the lifespan on the 3 main neuroimaging biomarkers. METHODS:Two hundred seven community-dwelling, cognitively normal APOE ε4 carriers and noncarriers aged 20-87 years were involved in this study. They underwent structural MRI, fluorodeoxygluc...

journal_title：Neurology

authors： Gonneaud J,Arenaza-Urquijo EM,Fouquet M,Perrotin A,Fradin S,de La Sayette V,Eustache F,Chételat G

更新日期：2016-10-18 00:00:00

abstract：OBJECTIVE:To examine the contribution of hepatitis C virus (HCV) infection to neurocognitive dysfunction in individuals with comorbid HIV infection or methamphetamine (METH) dependence. METHODS:Neurocognitive functioning was examined in 430 study participants who were either normal controls or had HCV infection, HIV i...

journal_title：Neurology

authors： Cherner M,Letendre S,Heaton RK,Durelle J,Marquie-Beck J,Gragg B,Grant I,HIV Neurobehavioral Research Center Group.

更新日期：2005-04-26 00:00:00

abstract：:There have been few descriptions of spontaneous epidural hematoma of the spinal cord in children. Duration of symptoms in previous cases has varied from hours to days. We recently evaluated a 6-year-old girl with cord compression from an extradural clot, who complained of thoracic back pain for 3 months before becomin...

journal_title：Neurology

authors： Robertson WC Jr,Lee YE,Edmonson MB

更新日期：1979-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the relationship of white matter hyperintensities (WMH) with decline in lower extremity function (LEF) over approximately 3 years in dementia-free older adults with memory complaints. METHODS:We obtained brain MRI data from 458 community-dwelling adults, aged 70 years or over, at baseline, and fr...

journal_title：Neurology

authors： Moon SY,de Souto Barreto P,Rolland Y,Chupin M,Bouyahia A,Fillon L,Mangin JF,Andrieu S,Cesari M,Vellas B,MAPT\/DSA Study Group.

更新日期：2018-04-10 00:00:00

abstract：:We measured monoamine metabolites and biopterin in the CSF of 37 patients with dementia of the Alzheimer type (DAT), with or without extrapyramidal signs, and in 14 age-matched healthy controls. Compared with concentrations in DAT and controls, the concentrations of homovanillic acid (HVA) and biopterin were significa...

journal_title：Neurology

authors： Kaye JA,May C,Daly E,Atack JR,Sweeney DJ,Luxenberg JS,Kay AD,Kaufman S,Milstien S,Friedland RP

更新日期：1988-04-01 00:00:00

abstract：OBJECTIVE:Aiming to detect associations between neuroradiologic and EEG evaluations and long-term clinical outcome in order to detect possible prognostic factors, a detailed clinical and neuroimaging characterization of 67 cases of Aicardi syndrome (AIC), collected through a multicenter collaboration, was performed. M...

journal_title：Neurology

authors： Masnada S,Pichiecchio A,Formica M,Arrigoni F,Borrelli P,Accorsi P,Bonanni P,Borgatti R,Bernardina BD,Danieli A,Darra F,Deconinck N,De Giorgis V,Dulac O,Gataullina S,Giordano L,Guerrini R,La Briola F,Mastrangelo M,Mo

更新日期：2020-12-04 00:00:00

abstract：:In Swiss mice, muscimol (3 mg per kilogram, intraperitoneally) caused myoclonic jerks of the hindquarters. These jerks were strong, repetitive, more or less regular, and of high frequency (peak response, 76 per minute). Pretreatment with sodium gamma-hydroxybutyrate (50 to 200 mg per kilogram) caused a dose-dependent ...

journal_title：Neurology

authors： Menon MK

更新日期：1982-04-01 00:00:00

abstract：OBJECTIVE:To determine the diagnostic accuracy and clinical utility of electromagnetic source imaging (EMSI) in presurgical evaluation of patients with epilepsy. METHODS:We prospectively recorded magnetoencephalography (MEG) simultaneously with EEG and performed EMSI, comprising electric source imaging, magnetic sourc...

journal_title：Neurology

authors： Duez L,Tankisi H,Hansen PO,Sidenius P,Sabers A,Pinborg LH,Fabricius M,Rásonyi G,Rubboli G,Pedersen B,Leffers AM,Uldall P,Jespersen B,Brennum J,Henriksen OM,Fuglsang-Frederiksen A,Beniczky S

更新日期：2019-02-05 00:00:00

abstract：OBJECTIVE:To study the accuracy of the ABCD2 score in predicting early stroke risk following TIA and to model post-test probability of stroke for varying cutoff scores and baseline stroke risk. METHODS:Medline, PubMed, Embase, conference proceedings, and manuscript references up to October 2010 were searched for studi...

journal_title：Neurology

authors： Sanders LM,Srikanth VK,Blacker DJ,Jolley DJ,Cooper KA,Phan TG

更新日期：2012-09-04 00:00:00

abstract：OBJECTIVE:To create and validate a simple, standardized version of the antisaccade (AS) task that requires no specialized equipment for use as a measure of executive function in multicenter clinical studies. METHODS:The bedside AS (BAS) task consisted of 40 pseudorandomized AS trials presented on a laptop computer. BA...

journal_title：Neurology

authors： Hellmuth J,Mirsky J,Heuer HW,Matlin A,Jafari A,Garbutt S,Widmeyer M,Berhel A,Sinha L,Miller BL,Kramer JH,Boxer AL

更新日期：2012-06-05 00:00:00

abstract：OBJECTIVE:To assess functional changes in lymphocyte repertoire and subsequent clinical implications during delayed-release dimethyl fumarate (DMF) treatment in patients with multiple sclerosis. METHODS:Using peripheral blood from several clinical trials of DMF, immune cell subsets were quantified using flow cytometry...

journal_title：Neurology

authors： Mehta D,Miller C,Arnold DL,Bame E,Bar-Or A,Gold R,Hanna J,Kappos L,Liu S,Matta A,Phillips JT,Robertson D,von Hehn CA,Campbell J,Spach K,Yang L,Fox RJ

更新日期：2019-04-09 00:00:00

abstract：OBJECTIVE:This study aims to evaluate protective effects of brief repetitive bilateral arm ischemic preconditioning (BAIPC) on stroke recurrence in patients with symptomatic atherosclerotic intracranial arterial stenosis (IAS). METHODS:A total of 68 consecutive cases with symptomatic IAS, diagnosed by imaging, were en...

journal_title：Neurology

authors： Meng R,Asmaro K,Meng L,Liu Y,Ma C,Xi C,Li G,Ren C,Luo Y,Ling F,Jia J,Hua Y,Wang X,Ding Y,Lo EH,Ji X

更新日期：2012-10-30 00:00:00

abstract：:We carried out a door-to-door-survey to screen a community of 14,010 people (Parsis living in colonies in Bombay, India) for possible neurologic diseases, and used defined diagnostic criteria to evaluate people who tested positive on the screening survey. There were three clinically definite cases of multiple sclerosi...

journal_title：Neurology

authors： Bharucha NE,Bharucha EP,Wadia NH,Singhal BS,Bharucha AE,Bhise AV,Kurtzke JF,Schoenberg BS

更新日期：1988-05-01 00:00:00