Effects of dietary linoleic acid on rat platelet ADP-induced aggregation and binding of 125I-fibrinogen.

Abstract:

:Platelets from rats fed a diet high in linoleic acid (6%) bound increased amounts of fibrinogen on stimulation with ADP, compared to those from rats fed diets with low (2%) or no linoleic acid. However, this increased fibrinogen binding was associated with a decrease in platelet aggregation induced by ADP. Changes in the linoleic acid concentration in platelet membranes may cause changes in this relationship.

journal_name

Thromb Res

journal_title

Thrombosis research

authors

McGregor L,Toor B,McGregor JL,Renaud S,Clemetson KJ

doi

10.1016/0049-3848(84)90107-5

subject

Has Abstract

pub_date

1984-04-01 00:00:00

pages

75-9

issue

1

eissn

0049-3848

issn

1879-2472

journal_volume

34

pub_type

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