当前位置： SCI文献检索 > JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY期刊下所有文献 > Applicability of ultrasonic tissue characterization for longitudinal assessment and differentiation of calcification and fibrosis in cardiomyopathy.

Applicability of ultrasonic tissue characterization for longitudinal assessment and differentiation of calcification and fibrosis in cardiomyopathy.

Abstract：

:Progress in tissue characterization of myocardium with ultrasound suggests that quantitative recognition of ischemic or scarred tissue will be achieved. Despite the increasing recognition and importance of cardiomyopathy, its diagnosis generally requires invasive procedures such as cardiac catheterization and biopsy. To investigate methods that permit the characterization of longitudinal cardiomyopathic changes that might ultimately be extended for noninvasive studies in patients, quantitative ultrasonic methods were utilized for in vitro tissue characterization of hearts from Syrian hamsters of selected age of either 2 to 3 or 5 to 7 months. Normal hamsters were used as controls. Myocardial sites (n = 600) from the young Syrian hamsters exhibited values (+/- standard error) of integrated ultrasonic backscatter averaging -53.87 +/- 0.26 dB, which were significantly different from values (n = 500) in age-matched control hamsters (-58.07 +/- 0.08 dB; p less than 0.001). Cardiomyopathic hearts from older animals exhibited backscatter values (n = 500 sites) averaging -50.87 +/- 0.22 dB, again significantly different from values (n = 300 sites) in age-matched control hamsters (-55.91 +/- 0.11 dB; p less than 0.001). In addition, ultrasonic attenuation was significantly different for hearts from the control and cardiomyopathic hamsters of both age ranges. The results correlated with sequential calcification and fibrosis characteristics assessed histopathologically. This study indicates that quantitative characterization of myocardium with ultrasound may permit longitudinal assessment of cardiomyopathic changes in diverse disease entities and their response to therapy.

journal_name

J Am Coll Cardiol

journal_title

Journal of the American College of Cardiology

authors

Pérez JE,Barzilai B,Madaras EI,Glueck RM,Saffitz JE,Johnston P,Miller JG,Sobel BE

doi

10.1016/s0735-1097(84)80323-x

subject

Has Abstract

pub_date

1984-07-01 00:00:00

pages

88-95

issue

1

eissn

0735-1097

issn

1558-3597

pii

S0735-1097(84)80323-X

journal_volume

4

pub_type

杂志文章

相关文献

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY文献大全
  • 18Fluorodeoxyglucose Accumulation in Arterial Tissues Determined by PET Signal Analysis.

    abstract：BACKGROUND:Arterial 18fluorodeoxyglucose (FDG) positron emission tomography (PET) is considered a measure of atherosclerotic plaque macrophages and is used for quantification of disease activity in clinical trials, but the distribution profile of FDG across macrophages and other arterial cells has not been fully clarif...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2019.06.057

    authors： Al-Mashhadi RH,Tolbod LP,Bloch LØ,Bjørklund MM,Nasr ZP,Al-Mashhadi Z,Winterdahl M,Frøkiær J,Falk E,Bentzon JF

    更新日期：2019-09-03 00:00:00

  • Nitroglycerin withdrawal increases endothelium-dependent vasomotor response to acetylcholine.

    abstract：OBJECTIVES:We sought to determine whether nitroglycerin (NTG) withdrawal contributes to worsening of endothelial dysfunction and development of the rebound phenomenon during intermittent transdermal NTG therapy. BACKGROUND:Intermittent transdermal NTG therapy is recommended to avoid the development of tolerance. Howev...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0735-1097(00)01140-2

    authors： Azevedo ER,Schofield AM,Kelly S,Parker JD

    更新日期：2001-02-01 00:00:00

  • Distribution of local repolarization changes produced by efferent vagal stimulation in the canine ventricles.

    abstract：:The purpose of this study was to compare the distribution of effects of right and left efferent vagal stimulation on ventricular recovery properties in the in situ heart. To measure these effects in many areas simultaneously, local repolarization changes (local QT intervals) were recorded with bipolar electrodes in ni...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(83)80350-7

    authors： Martins JB,Zipes DP,Lund DD

    更新日期：1983-12-01 00:00:00

  • Gender-related differences in the central arterial pressure waveform.

    abstract：OBJECTIVES:This study investigated the effect of age and gender on central arterial hemodynamic variables derived from noninvasive tonometric carotid pressure waveforms. BACKGROUND:Women have a greater age-related increase in left ventricular (LV) mass than do men and are more likely to experience symptomatic heart fa...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(97)00378-1

    authors： Hayward CS,Kelly RP

    更新日期：1997-12-01 00:00:00

  • Body surface mapping of counterclockwise and clockwise typical atrial flutter: a comparative analysis with endocardial activation sequence mapping.

    abstract：OBJECTIVES:This study was directed at developing spatial 62-lead electrocardiogram (ECG) criteria for classification of counterclockwise (CCW) and clockwise (CW) typical atrial flutter (Fl) in patients with and without structural heart disease. BACKGROUND:Electrocardiographic classification of CCW and CW typical atria...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(00)00549-0

    authors： SippensGroenewegen A,Lesh MD,Roithinger FX,Ellis WS,Steiner PR,Saxon LA,Lee RJ,Scheinman MM

    更新日期：2000-04-01 00:00:00

  • Coronary revascularization in the elderly patient.

    abstract：:A total of 1,275 elderly patients (70 years and older) underwent coronary artery bypass alone from 1970 to 1981. The percent of elderly patients who underwent coronary bypass surgery alone increased from 2.04% in 1971 to 8.2% in 1981. Most of the patients had severe, disabling or unstable angina pectoris. The overall ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(84)80277-6

    authors： Elayda MA,Hall RJ,Gray AG,Mathur VS,Cooley DA

    更新日期：1984-06-01 00:00:00

  • Aortic Bioprosthetic Valve Durability: Incidence, Mechanisms, Predictors, and Management of Surgical and Transcatheter Valve Degeneration.

    abstract：:In recent times, there has been a considerable increase in the use of aortic bioprostheses (vs. mechanical prostheses) for treating aortic valve disease, and this tendency is likely to continue in the near future. However, the occurrence of structural valve degeneration, limiting valve durability, remains an important...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2017.07.715

    authors： Rodriguez-Gabella T,Voisine P,Puri R,Pibarot P,Rodés-Cabau J

    更新日期：2017-08-22 00:00:00

  • Protective effects of erythropoietin in cardiac ischemia: from bench to bedside.

    abstract：:Erythropoietin (EPO) is a hypoxia-induced hormone produced in the kidneys that stimulates hematopoiesis in the bone marrow. However, recent studies have also shown important nonhematopoietic effects of EPO. A functional EPO receptor is found in the cardiovascular system, including endothelial cells and cardiomyocytes....

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jacc.2006.08.031

    authors： Lipsic E,Schoemaker RG,van der Meer P,Voors AA,van Veldhuisen DJ,van Gilst WH

    更新日期：2006-12-05 00:00:00

  • Late increase in luminal diameter of aortocoronary venous bypass grafts associated with an increase in the vascular region under supply.

    abstract：:In a previous study, a significant inverse relation was found between the luminal size of aortocoronary venous bypass grafts and the vascular resistance of the coronary region that was perfused by the bypass graft in late stages after bypass surgery. This observation suggested that changes in the graft-dependent vascu...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(87)80153-5

    authors： Herrmann G,Simon R,Amende I,Frank G,Borst HG,Lichtlen PR

    更新日期：1987-07-01 00:00:00

  • Evaluation of left ventricular systolic and diastolic dysfunction during transient myocardial ischemia produced by angioplasty.

    abstract：:Acute myocardial ischemia is known to cause impairment of both left ventricular systolic and diastolic function. To further investigate these changes as well as their relation to common clinical variables (electrocardiographic [ECG] changes and chest pain), 32 patients were evaluated with Doppler echocardiography duri...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(87)80266-8

    authors： Labovitz AJ,Lewen MK,Kern M,Vandormael M,Deligonal U,Kennedy HL

    更新日期：1987-10-01 00:00:00

  • Manual thrombus-aspiration improves myocardial reperfusion: the randomized evaluation of the effect of mechanical reduction of distal embolization by thrombus-aspiration in primary and rescue angioplasty (REMEDIA) trial.

    abstract：OBJECTIVES:The aim of this study was to evaluate the use of a new manual thrombus-aspirating device in unselected patients with ST-segment elevation acute myocardial infarction (STEMI) undergoing urgent percutaneous coronary intervention (PCI). BACKGROUND:Failure to achieve myocardial reperfusion often occurs during P...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/j.jacc.2005.04.057

    authors： Burzotta F,Trani C,Romagnoli E,Mazzari MA,Rebuzzi AG,De Vita M,Garramone B,Giannico F,Niccoli G,Biondi-Zoccai GG,Schiavoni G,Mongiardo R,Crea F

    更新日期：2005-07-19 00:00:00

  • Cellular, but not direct, adenoviral delivery of vascular endothelial growth factor results in improved left ventricular function and neovascularization in dilated ischemic cardiomyopathy.

    abstract：OBJECTIVES:We sought to compare the effects on angiogenesis and left ventricular (LV) function of adenoviral vascular endothelial growth factor-165 (AdVEGF-165) gene delivery by direct injection of AdVEGF-165 to the transplantation of skeletal myoblasts (SKMB) transfected with AdVEGF-165 in a rat model of ischemic card...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2003.12.045

    authors： Askari A,Unzek S,Goldman CK,Ellis SG,Thomas JD,DiCorleto PE,Topol EJ,Penn MS

    更新日期：2004-05-19 00:00:00

  • Vascular repair after balloon overstretch injury in porcine model effects of intracoronary radiation.

    abstract：OBJECTIVES:The purpose of this study was to evaluate the effect of IR on thrombus formation and dissection repair following overstretch balloon injury in porcine coronary arteries. BACKGROUND:Exposure of blood to the injured arterial wall after percutaneous transluminal coronary angioplasty (PTCA) induces thrombus for...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(00)00851-2

    authors： Cottin Y,Kollum M,Chan R,Bhargava B,Vodovotz Y,Waksman R

    更新日期：2000-10-01 00:00:00

  • Clinical correlates of PR-segment depression in asymptomatic patients with pericardial effusion.

    abstract：OBJECTIVES:The purpose of this study was to determine the clinical correlates of PR-segment depression among consecutive asymptomatic patients with pericardial effusion (PE) detected by routine echocardiography. BACKGROUND:Pericardial effusion is a relatively common finding in clinical practice, but not many studies h...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(02)01889-2

    authors： Kudo Y,Yamasaki F,Doi Y,Sugiura T

    更新日期：2002-06-19 00:00:00

  • The oxygen free radical system: potential mediator of myocardial injury.

    abstract：:The sequential univalent reduction of oxygen gives rise to very reactive intermediate products including superoxide anion radical, hydrogen peroxide and free hydroxyl radicals. Normally, the tissue concentration of these intermediate products of oxygen is severely limited; however, if oxygen free radicals are produced...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(85)80278-3

    authors： Hammond B,Hess ML

    更新日期：1985-07-01 00:00:00

  • Homocysteine and coronary atherosclerosis.

    abstract：:Homocysteine is increasingly recognized as a risk factor for coronary artery disease. An understanding of its metabolism and of the importance of vitamins B6 and B12 and folate as well as enzyme levels in its regulation will aid the development of therapeutic strategies that, by lowering circulating concentrations, ma...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/0735-1097(95)00508-0

    authors： Mayer EL,Jacobsen DW,Robinson K

    更新日期：1996-03-01 00:00:00

  • Nationwide Trends of Hospital Admission and Outcomes Among Critical Limb Ischemia Patients: From 2003-2011.

    abstract：BACKGROUND:Critical limb ischemia (CLI) continues to be a major cause of vascular-related morbidity and mortality in the United States. OBJECTIVES:The study sought to characterize the trends in hospitalization of U.S. patients with CLI from 2003 to 2011, using the Nationwide Inpatient Sample. We compared the cost util...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2016.02.040

    authors： Agarwal S,Sud K,Shishehbor MH

    更新日期：2016-04-26 00:00:00

  • Mechanisms of early death despite thrombolytic therapy: experience from the Thrombolysis in Myocardial Infarction Phase II (TIMI II) study.

    abstract：:Mechanisms of death among patients who died within 18 h of enrollment in the Thrombolysis in Myocardial Infarction Phase II (TIMI II) study were analyzed. Of 3,339 patients enrolled, 32 died within the 1st 4 h and 31 died within the subsequent 14 h. Thirteen of the 63 patients had shock at enrollment; 22 had advanced ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1016/0735-1097(92)90313-c

    authors： Kleiman NS,Terrin M,Mueller H,Chaitman B,Roberts R,Knatterud GL,Solomon R,McMahon RP,Braunwald E

    更新日期：1992-05-01 00:00:00

  • Influence of Sacubitril/Valsartan (LCZ696) on 30-Day Readmission After Heart Failure Hospitalization.

    abstract：BACKGROUND:Patients with heart failure (HF) are at high risk for hospital readmission in the first 30 days following HF hospitalization. OBJECTIVES:This study sought to determine if treatment with sacubitril/valsartan (LCZ696) reduces rates of hospital readmission at 30-days following HF hospitalization compared with ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.jacc.2016.04.047

    authors： Desai AS,Claggett BL,Packer M,Zile MR,Rouleau JL,Swedberg K,Shi V,Lefkowitz M,Starling R,Teerlink J,McMurray JJV,Solomon SD,PARADIGM-HF Investigators.

    更新日期：2016-07-19 00:00:00

  • Coronary patency after intravenous infusion of recombinant tissue-type plasminogen activator in acute myocardial infarction.

    abstract：:The relation between coronary patency after infusion of recombinant tissue-type plasminogen activator (rt-PA) and clinical and laboratory findings was assessed in patients with acute myocardial infarction. This study focused primarily on information available early in the hospitalization phase. Data were available for...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(88)90196-9

    authors： Brower RW,Arnold AE,Lubsen J,Verstraete M

    更新日期：1988-04-01 00:00:00

  • Intravascular ultrasound study of angiographically mildly diseased coronary arteries.

    abstract：OBJECTIVES:We hypothesized that intravascular ultrasound may identify significant coronary artery narrowing in the mildly diseased coronary artery of patients with insignificant or one- or two-vessel coronary artery disease. BACKGROUND:Necropsy studies have revealed that coronary angiography may underestimate stenosis...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(93)90770-2

    authors： Porter TR,Sears T,Xie F,Michels A,Mata J,Welsh D,Shurmur S

    更新日期：1993-12-01 00:00:00

  • Acute hemodynamic effects of adjustable atrial septal defect closure in the lateral tunnel Fontan procedure.

    abstract：OBJECTIVES:This study evaluated the acute hemodynamic changes with atrial septal defect closure in the postoperative period in patients undergoing the Fontan procedure. BACKGROUND:The adjustable atrial septal defect is a modification of the Fontan procedure designed to improve cardiac output and reduce systemic venous...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(94)90673-4

    authors： Harake B,Kuhn MA,Jarmakani JM,Laks H,al-Khatib Y,Elami A,Williams RG

    更新日期：1994-06-01 00:00:00

  • Ambrisentan therapy for pulmonary arterial hypertension.

    abstract：OBJECTIVES:The purpose of this study was to examine the efficacy and safety of four doses of ambrisentan, an oral endothelin type A receptor-selective antagonist, in patients with pulmonary arterial hypertension (PAH). BACKGROUND:Pulmonary arterial hypertension is a life-threatening and progressive disease with limite...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/j.jacc.2005.04.050

    authors： Galié N,Badesch D,Oudiz R,Simonneau G,McGoon MD,Keogh AM,Frost AE,Zwicke D,Naeije R,Shapiro S,Olschewski H,Rubin LJ

    更新日期：2005-08-02 00:00:00

  • Multicenter evaluation of carotid artery stenting with a filter protection system.

    abstract：OBJECTIVES:The aim of this study was to evaluate the feasibility and safety of carotid artery stenting (CAS) with a filter protection system. BACKGROUND:Neurologic events linked to the embolization of particulate matter to the cerebral circulation may complicate CAS. Strategies designed to capture embolic particles du...

    journal_title：Journal of the American College of Cardiology

    pub_type： 临床试验,杂志文章,多中心研究

    doi：10.1016/s0735-1097(02)01692-3

    authors： Al-Mubarak N,Colombo A,Gaines PA,Iyer SS,Corvaja N,Cleveland TJ,Macdonald S,Brennan C,Vitek JJ

    更新日期：2002-03-06 00:00:00

  • Single-photon emission computed tomography myocardial perfusion imaging and the risk of sudden cardiac death in patients with coronary disease and left ventricular ejection fraction>35%.

    abstract：OBJECTIVES:The aim of this study was to determine whether single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is an effective method of risk stratification for sudden cardiac death (SCD) in patients with coronary artery disease (CAD) and left ventricular ejection fraction (LVEF)>35%. ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2010.01.061

    authors： Piccini JP,Starr AZ,Horton JR,Shaw LK,Lee KL,Al-Khatib SM,Iskandrian AE,O'Connor CM,Borges-Neto S

    更新日期：2010-07-13 00:00:00

  • Characterization of the functional border zone around regionally ischemic myocardium using circumferential flow-function maps.

    abstract：:Previous studies have suggested that there exists a functional border zone in myocardium at the lateral margins of an ischemic area. The functional border zone is normally perfused but is characterized by abnormal contractile function. To define the spatial characteristics of this border zone, circumferential maps of ...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(86)80106-1

    authors： Buda AJ,Zotz RJ,Gallagher KP

    更新日期：1986-07-01 00:00:00

  • Prognostic implications of atrial fibrillation in patients undergoing myocardial perfusion single-photon emission computed tomography.

    abstract：OBJECTIVES:The aim of this research was to determine whether presence of atrial fibrillation (AF) provides incremental prognostic information relative to myocardial perfusion single-photon emission computed tomography (MPS) with respect to risk of cardiac death (CD). BACKGROUND:The prognostic significance of AF in pat...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2004.05.076

    authors： Abidov A,Hachamovitch R,Rozanski A,Hayes SW,Santos MM,Sciammarella MG,Cohen I,Gerlach J,Friedman JD,Germano G,Berman DS

    更新日期：2004-09-01 00:00:00

  • Incorporating Coronary Calcification Into Pre-Test Assessment of the Likelihood of Coronary Artery Disease.

    abstract：BACKGROUND:The prevalence of obstructive coronary artery disease (CAD) in symptomatic patients referred for diagnostic testing has declined, warranting optimization of individualized diagnostic strategies. OBJECTIVES:This study sought to present a simple, clinically applicable tool enabling estimation of the likelihoo...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/j.jacc.2020.09.585

    authors： Winther S,Schmidt SE,Mayrhofer T,Bøtker HE,Hoffmann U,Douglas PS,Wijns W,Bax J,Nissen L,Lynggaard V,Christiansen JJ,Saraste A,Bøttcher M,Knuuti J

    更新日期：2020-11-24 00:00:00

  • Predictors of the success or failure of medical therapy in patients with chronic recurrent sustained ventricular tachycardia: a discriminant analysis.

    abstract：:To identify predictors of the success or failure of medical therapy in chronic recurrent sustained ventricular tachycardia, univariate and multivariate statistical techniques were used to retrospectively analyze data in 84 patients with this arrhythmia. By univariate analysis, four factors were associated with success...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/s0735-1097(83)80066-7

    authors： Spielman SR,Schwartz JS,McCarthy DM,Horowitz LN,Greenspan AM,Sadowski LM,Josephson ME,Waxman HL

    更新日期：1983-02-01 00:00:00

  • Nonsurgical closure of femoral pseudoaneurysms complicating cardiac catheterization and percutaneous transluminal coronary angioplasty.

    abstract：OBJECTIVES:This study was performed to describe the initial experience and follow-up of ultrasound-guided compression of pseudoaneurysms in patients receiving systemic anticoagulant or antiplatelet therapy, or both, after recent cardiac catheterization or percutaneous transluminal coronary angioplasty. BACKGROUND:Femo...

    journal_title：Journal of the American College of Cardiology

    pub_type： 杂志文章

    doi：10.1016/0735-1097(92)90015-f

    authors： Agrawal SK,Pinheiro L,Roubin GS,Hearn JA,Cannon AD,Macander PJ,Barnes JL,Dean LS,Nanda NC

    更新日期：1992-09-01 00:00:00