The oxygen free radical system: potential mediator of myocardial injury.

abstract：:Certain clinical and cardiac morphologic findings are described in 22 patients, aged 45 to 80 years (mean 64) (15 men [68%]), in whom rupture of a papillary muscle occurred during acute myocardial infarction. In most, the acute infarction associated with papillary muscle rupture was a first coronary event (only 18% ha...

journal_title：Journal of the American College of Cardiology

authors： Barbour DJ,Roberts WC

更新日期：1986-09-01 00:00:00

abstract：:The 2013 (with updates in 2016 and 2017) American College of Cardiology/American Heart Association and 2016 European Society of Cardiology guidelines provide practical evidence-based clinical guidelines for the diagnosis and treatment of both acute and chronic heart failure (HF). Both guidelines address noninvasive an...

journal_title：Journal of the American College of Cardiology

authors： van der Meer P,Gaggin HK,Dec GW

更新日期：2019-06-04 00:00:00

abstract：OBJECTIVES:We assessed the incremental value of baseline Q waves over time from symptom onset as a marker of clinical outcome in ST-segment elevation myocardial infarction (STEMI). BACKGROUND:Time from symptom onset is a central focus in STEMI patients. The presence of Q waves on the baseline electrocardiogram (ECG) h...

journal_title：Journal of the American College of Cardiology

authors： Armstrong PW,Fu Y,Westerhout CM,Hudson MP,Mahaffey KW,White HD,Todaro TG,Adams PX,Aylward PE,Granger CB

更新日期：2009-04-28 00:00:00

abstract：OBJECTIVES:We sought to evaluate whether fasting hyperhomocystinemia reduces endothelial function by oxidative stress in normotensive subjects and hypertensive patients. BACKGROUND:Subjects with hyperhomocystinemia have endothelial dysfunction. METHODS:In 23 normotensive subjects and 28 hypertensive patients, classif...

journal_title：Journal of the American College of Cardiology

authors： Virdis A,Ghiadoni L,Cardinal H,Favilla S,Duranti P,Birindelli R,Magagna A,Bernini G,Salvetti G,Taddei S,Salvetti A

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVES:We sought to investigate the effect of cardiac medication on long-term mortality in patients with peripheral arterial disease (PAD). BACKGROUND:Peripheral arterial disease is associated with increased cardiovascular morbidity and mortality. Treatment guidelines recommend aggressive management of risk factor...

journal_title：Journal of the American College of Cardiology

authors： Feringa HH,van Waning VH,Bax JJ,Elhendy A,Boersma E,Schouten O,Galal W,Vidakovic RV,Tangelder MJ,Poldermans D

更新日期：2006-03-21 00:00:00

abstract：BACKGROUND:Pheochromocytoma is associated with catecholamine-induced cardiac toxicity, but the extent and nature of cardiac involvement in clinical cohorts is not well-characterized. OBJECTIVES:This study characterized the cardiac phenotype in patients with pheochromocytoma using cardiac magnetic resonance (CMR). MET...

journal_title：Journal of the American College of Cardiology

authors： Ferreira VM,Marcelino M,Piechnik SK,Marini C,Karamitsos TD,Ntusi NAB,Francis JM,Robson MD,Arnold JR,Mihai R,Thomas JDJ,Herincs M,Hassan-Smith ZK,Greiser A,Arlt W,Korbonits M,Karavitaki N,Grossman AB,Wass JAH,Neubaue

更新日期：2016-05-24 00:00:00

abstract：OBJECTIVES:The purpose of this study was to evaluate the role of the myocardial redox state in the development of in-hospital complications after cardiac surgery and the effect of statins on the myocardial redox state. BACKGROUND:Statins improve clinical outcome after cardiac surgery, but it is unclear whether they ex...

journal_title：Journal of the American College of Cardiology

authors： Antoniades C,Demosthenous M,Reilly S,Margaritis M,Zhang MH,Antonopoulos A,Marinou K,Nahar K,Jayaram R,Tousoulis D,Bakogiannis C,Sayeed R,Triantafyllou C,Koumallos N,Psarros C,Miliou A,Stefanadis C,Channon KM,Casadei B

更新日期：2012-01-03 00:00:00

abstract：OBJECTIVES:The aim of this study was to examine the effects of essential hypertension on cardiac autonomic function in type 2 diabetic patients. BACKGROUND:Hypertension is common in type 2 diabetic patients and is associated with a high mortality. However, the combined effects of type 2 diabetes and essential hyperten...

journal_title：Journal of the American College of Cardiology

authors： Takahashi N,Nakagawa M,Saikawa T,Ooie T,Yufu K,Shigematsu S,Hara M,Sakino H,Katsuragi I,Okeda T,Yoshimatsu H,Sakata T

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVES:We evaluated the effects of growth hormone (GH) on survival in experimental heart failure (HF). BACKGROUND:Growth hormone has been beneficial in various models of experimental HF. Whether GH also affects HF progression and survival is not known. METHODS:A total of 119 rats with moderate myocardial infarcti...

journal_title：Journal of the American College of Cardiology

authors： Cittadini A,Isgaard J,Monti MG,Casaburi C,Di Gianni A,Serpico R,Iaccarino G,Saccà L

更新日期：2003-06-18 00:00:00

abstract：:It has now been a quarter of a century since the first description by Kitabatake and his associates of the use of echo-Doppler to characterize the transmitral flow velocity curves in various disease states. A decade ago we described the role of echocardiography in the "Evaluation of Diastolic Filling of Left Ventricle...

journal_title：Journal of the American College of Cardiology

authors： Lester SJ,Tajik AJ,Nishimura RA,Oh JK,Khandheria BK,Seward JB

更新日期：2008-02-19 00:00:00

abstract：:An international survey identified 40 patients less than 20 years old who underwent surgical implantation of an automatic implantable cardioverter-defibrillator (AICD). There was a history of aborted sudden cardiac death or sustained ventricular tachycardia in 92.5% of these patients. Twenty-two patients (55%) had str...

journal_title：Journal of the American College of Cardiology

authors： Kron J,Oliver RP,Norsted S,Silka MJ

更新日期：1990-10-01 00:00:00

abstract：OBJECTIVES:We sought to determine whether the introduction of these agents had altered the outcome of dilated cardiomyopathy (DC) in childhood. BACKGROUND:Pediatric DC has a poor prognosis. Angiotensin-converting enzyme inhibitors (ACEIs) and beta-adrenergic receptor blockers (BBs) improve survival in adults with DC, ...

journal_title：Journal of the American College of Cardiology

authors： Kantor PF,Abraham JR,Dipchand AI,Benson LN,Redington AN

更新日期：2010-03-30 00:00:00

abstract：OBJECTIVES:To optimize percutaneous coronary intervention (PCI) strategy for unprotected left main (LM) disease, we performed a randomized study: intravascular ultrasound (IVUS)-guided bare-metal stent (BMS) or paclitaxel-eluting stent (PES) implantation after lesion pre-treatment with cutting balloon (CB) for unprotec...

journal_title：Journal of the American College of Cardiology

authors： Erglis A,Narbute I,Kumsars I,Jegere S,Mintale I,Zakke I,Strazdins U,Saltups A

更新日期：2007-08-07 00:00:00

abstract：:In advanced heart failure, mitral regurgitation increases the burden of the failing ventricle and decreases effective stroke volume. Although tailored afterload reduction decreases mitral regurgitation at rest, it is not known if this benefit is maintained during upright exercise. Simultaneous radionuclide ventriculog...

journal_title：Journal of the American College of Cardiology

authors： Stevenson LW,Brunken RC,Belil D,Grover-McKay M,Schwaiger M,Schelbert HR,Tillisch JH

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVES:This study sought to evaluate the associations between different measures of obesity and prevalent atherosclerosis in a large population-based cohort. BACKGROUND:Although obesity is associated with cardiovascular mortality, it is unclear whether this relationship is mediated by increased atherosclerotic bur...

journal_title：Journal of the American College of Cardiology

authors： See R,Abdullah SM,McGuire DK,Khera A,Patel MJ,Lindsey JB,Grundy SM,de Lemos JA

更新日期：2007-08-21 00:00:00

abstract：OBJECTIVES:This study was conducted to assess the need for, and use of, fenestration of an extracardiac conduit Fontan. BACKGROUND:Fenestration of a Fontan connection has been proposed as a means of improving outcomes of single ventricle palliation. The benefit of fenestration is likely to be greatest in the early pos...

journal_title：Journal of the American College of Cardiology

authors： Thompson LD,Petrossian E,McElhinney DB,Abrikosova NA,Moore P,Reddy VM,Hanley FL

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVES:We sought to assess the possible relations between clinical severity of chronic heart failure and catabolic factors, specifically tumor necrosis factor (TNF), soluble TNF receptors 1 and 2 (sTNFR-1 and sTNFR-2), cortisol, testosterone and dehydroepiandrosterone (DHEA). BACKGROUND:Chronic heart failure is as...

journal_title：Journal of the American College of Cardiology

authors： Anker SD,Clark AL,Kemp M,Salsbury C,Teixeira MM,Hellewell PG,Coats AJ

更新日期：1997-10-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to identify predictors of defibrillation threshold in patients undergoing epicardial defibrillator implantation. BACKGROUND:Factors that predict epicardial defibrillation efficacy are poorly defined. METHODS:The data from 375 consecutive adult patients were reviewed. After e...

journal_title：Journal of the American College of Cardiology

authors： Leitch JW,Yee R

更新日期：1993-06-01 00:00:00

abstract：:Twelve cardiac electrophysiology centers conducted an open label prospective trial of bethanidine sulfate, an oral bretylium analog, for the prevention of ventricular tachyarrhythmias during programmed electrical stimulation. The study group included 56 patients (44 men, 12 women; mean age 60 years; 55 with structural...

journal_title：Journal of the American College of Cardiology

authors： Teichman SL,Waspe LE,Matos JA,Kim SG,Fisher JD

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVES:The study was done to characterize the electrocardiographic and electrophysiologic features of focal atrial tachycardia originating at the mitral annulus (MA). BACKGROUND:Though the majority of left atrial tachycardias originate around the ostia of the pulmonary veins, only isolated reports have described f...

journal_title：Journal of the American College of Cardiology

authors： Kistler PM,Sanders P,Hussin A,Morton JB,Vohra JK,Sparks PB,Kalman JM

更新日期：2003-06-18 00:00:00

abstract：OBJECTIVES:The hypothesis of this study was that evaluation of myocardial flow and metabolism using nitrogen-13 (N-13) ammonia kinetic modeling with dynamic positron emission tomographic (PET) imaging could identify regions of myocardial scar and viable myocardium as defined by fluorine-18 fluorodeoxyglucose (F-18 FDG)...

journal_title：Journal of the American College of Cardiology

authors： Beanlands RS,deKemp R,Scheffel A,Nahmias C,Garnett ES,Coates G,Johansen HL,Fallen E

更新日期：1997-03-01 00:00:00

abstract：:Anthracycline compounds are major culprits in chemotherapy-induced cardiotoxicity, which is the chief limiting factor in delivering optimal chemotherapy to cancer patients. Although extensive efforts have been devoted to identifying strategies to prevent anthracycline-induced cardiotoxicity, there is little consensus ...

journal_title：Journal of the American College of Cardiology

authors： Vejpongsa P,Yeh ET

更新日期：2014-09-02 00:00:00

abstract：:Both activation of platelets and elevation of plasminogen activator inhibitor type 1 (PAI-1) activity in plasma have been associated with acute myocardial infarction. Growth factors from platelet alpha-granules have been shown to increase PAI-1 synthesis in liver and endothelial cells in culture. The present study was...

journal_title：Journal of the American College of Cardiology

authors： Fujii S,Abendschein DR,Sobel BE

更新日期：1991-11-15 00:00:00

abstract：:The purpose of this study was to examine whether remodeling of the aorta takes place after successful balloon angioplasty of aortic coarctation. During the 35 month period ending in December 1987, 30 children, aged 14 days to 13 years, underwent balloon angioplasty of unoperated aortic coarctation, with a resultant re...

journal_title：Journal of the American College of Cardiology

authors： Rao PS,Carey P

更新日期：1989-11-01 00:00:00

abstract：OBJECTIVES:The study compared the influence of sympathetic stimulation on transmural and spatial dispersion of repolarization between LQT1 and LQT2 forms of congenital long QT sYndrome (LQTS). BACKGROUND:Cardiac events are more associated with sympathetic stimulation in LQT1 than in LQT2 or LQT3 syndrome. Experimental...

journal_title：Journal of the American College of Cardiology

authors： Tanabe Y,Inagaki M,Kurita T,Nagaya N,Taguchi A,Suyama K,Aihara N,Kamakura S,Sunagawa K,Nakamura K,Ohe T,Towbin JA,Priori SG,Shimizu W

更新日期：2001-03-01 00:00:00

abstract：:A patient is described who underwent atrial septal defect repair at age 12 and presented 16 years later with angina. Coronary angiography revealed a right coronary artery to pulmonary artery fistula that had developed at the site of the previous thoracotomy. This is the first report of an acquired fistula of this type...

journal_title：Journal of the American College of Cardiology

authors： Rothschild AH,Adatepe MH,Magovern GJ,Rothschild MA,Joyner CR

更新日期：1985-10-01 00:00:00

abstract：:Sudden cardiac death accounts for approximately 300,000 deaths annually in the U.S., and most of these are secondary to ventricular tachycardia (VT) and fibrillation in patients with coronary artery disease. Most patients with cardiac death die before reaching the hospital, which brought about a tremendous amount of r...

journal_title：Journal of the American College of Cardiology

authors： Welch PJ,Page RL,Hamdan MH

更新日期：1999-09-01 00:00:00

abstract：OBJECTIVES:We evaluated the efficacy and safety of the percutaneous ventricular assist device (pVAD) in patients in severe refractory cardiogenic shock (SRCS) despite intra-aortic balloon pump (IABP) and/or high-dose vasopressor support. BACKGROUND:SRCS is associated with substantial mortality despite IABP counterpuls...

journal_title：Journal of the American College of Cardiology

authors： Kar B,Gregoric ID,Basra SS,Idelchik GM,Loyalka P

更新日期：2011-02-08 00:00:00

abstract：:Serum levels of DHEA sulfate are inversely associated with cardiovascular death in men, and urinary dehydroepiandrosterone (DHEA) levels are inversely associated with clinical manifestations of coronary artery disease. These observations may be related to the antiproliferative effects of DHEA, resulting in inhibition ...

journal_title：Journal of the American College of Cardiology

authors： Herrington DM,Gordon GB,Achuff SC,Trejo JF,Weisman HF,Kwiterovich PO Jr,Pearson TA

更新日期：1990-11-01 00:00:00

abstract：OBJECTIVES:This study sought to assess the diagnostic value of optical coherence tomography (OCT) in patients with suspected spontaneous coronary artery dissection (SCAD). BACKGROUND:SCAD is a rare but challenging clinical entity. METHODS:Following a prospective protocol, OCT was performed in 17 consecutive patients ...

journal_title：Journal of the American College of Cardiology

authors： Alfonso F,Paulo M,Gonzalo N,Dutary J,Jimenez-Quevedo P,Lennie V,Escaned J,Bañuelos C,Hernandez R,Macaya C

更新日期：2012-03-20 00:00:00