Abstract：
:Trypanosoma cruzi virulence factors include molecules expressed on the cell surface as well as those secreted or shed into the extracellular medium. Phosphatase activities modulate different aspects of T. cruzi infection, although no studies to date addressed the presence and activity of phosphatases in vesicles secreted by this parasite. Here, we characterized acidic and alkaline secreted phosphatase activities of human-infective trypomastigote forms of T. cruzi from the Y strain and the CL-Brener clone. These are widely studied T. cruzi strains that represent "opposite ends of the spectrum" regarding both in vitro and in vivo behavior. Ecto-phosphatase activities were determined in live parasites, and secreted phosphatase activities were analyzed in soluble protein (SP) and vesicular membrane fractions (VFs) of parasite-conditioned medium. Our analysis using different phosphatase inhibitors strongly suggests that vesicles secreted by Y strain (VF(Y)) and CL-Brener (VF(CLB)) trypomastigotes are derived mostly from the cell surface and from exosome secretion, respectively. Importantly, our results show that the acid phosphatase activities in vesicles secreted by trypomastigotes are largely responsible for the VF-induced increase in adhesion of Y strain parasites to host cells and also for the VF-induced increase in host cell infection by CL-Brener trypomastigotes.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Neves RF,Fernandes AC,Meyer-Fernandes JR,Souto-Padrón Tdoi
10.1007/s00436-014-3958-xsubject
Has Abstractpub_date
2014-08-01 00:00:00pages
2961-72issue
8eissn
0932-0113issn
1432-1955journal_volume
113pub_type
杂志文章abstract：:Numerous species of Sarcocystis have been reported from wild ruminants, but none has been named from the Rocky Mountain goat (Oreamnos americanus). Mature sarcocysts were found in frozen muscle samples of three of seven mountain goats from Alaska, USA. Two morphological types of sarcocysts were found; one had Sarcocys...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-015-4644-3
更新日期：2015-11-01 00:00:00
abstract：:Following the emergence of Schmallenberg virus (SBV) in 2011, 21,397 culicoid biting midges (Diptera: Ceratopogonidae) from targeted and non-targeted sampling activities carried out during the summer months of 2011 to 2013 and in late 2014 in various regions in Germany were analyzed for the virus by real-time RT-PCR. ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-015-4768-5
更新日期：2016-02-01 00:00:00
abstract：:Leishmaniasis is a geographically widespread disease caused by protozoan parasites belonging to the genus Leishmania and transmitted by certain species of sand fly. This disease still remains endemic in China, especially in the west and northwest frontier regions. A recent ITS1 phylogeny of Chinese Leishmania isolates...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-010-2239-6
更新日期：2011-07-01 00:00:00
abstract：:In 2002, Skerratt et al. phylogenetically analysed sequence data for several haplotypes of the parasitic mite Sarcoptes scabiei from wombat, human and dog hosts in Australia, to test scenarios concerning the origin and diversification of the scabies infections in wombats. Here we note that their substantive conclusion...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-003-0987-2
更新日期：2003-12-01 00:00:00
abstract：:In freshwater ecosystems, snails can significantly influence the competition between primary producers through grazing of periphyton. This activity can potentially be modified by trematodes, a large group of parasites which mostly use molluscs as the first intermediate host. Available studies, however, show contradict...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-6052-y
更新日期：2018-11-01 00:00:00
abstract：:Leishmania has distinct epidemiological and biological characteristics and causes a variety of clinical symptoms. To understand the genetic diversity and the phylogenetic relationships among Leishmania isolates from China, 29 Leishmania isolates from different geographic origins, vectors, and hosts were analyzed using...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-010-1814-1
更新日期：2010-05-01 00:00:00
abstract：:Infections of Eimeria tenella in chicken embryos were used to compare the anticoccidial activity of ten drugs. The minimal inhibitory concentration (MIC) and minimal toxic concentration (MTC) were affected by the time of inoculation into the embryos and by the chemical nature of the compounds. Some compounds (nicarbaz...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00931020
更新日期：1991-01-01 00:00:00
abstract：:Seventy-five previously frozen Northern Lapwings, Vanellus vanellus (Linnaeus, 1758) were dissected and examined for trematodes. The available birds were euthanized after suffering severe injuries from a hail storm. Trematode specimens were found in the air sacs, body cavities and kidneys. They were cleared, stained i...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-016-5330-9
更新日期：2017-02-01 00:00:00
abstract：:Light, scanning and transmission electron microscope examinations of adult Cystidicoloides ephemeridarum nematodes, parasitic in the stomach of brown trout (Salmo trutta fario L.), revealed that the body wall is composed of a cuticle, a hypodermis and longitudinally oriented somatic musculature. The body cuticle is co...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-003-0935-1
更新日期：2003-09-01 00:00:00
abstract：:The development of the metacestode stages of Arostrilepis microtis (Eucestoda: Hymenolepididae) studied on the basis of an experimental infection of springtails (Collembola: Entomobryidae) is described for the first time. A complete description of the ontogeny from oncosphere to fully a developed metacestode is given....
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-5929-0
更新日期：2018-08-01 00:00:00
abstract：:Babesiosis is a protozoal disease caused by Babesia spp. in mammals and humans worldwide. It is one of the most important tick-borne diseases, which affects livestock productions, reproductions, and accordingly failing economy. In this, systematic review and meta-analysis, study, the prevalence of babesiosis among dom...
journal_title：Parasitology research
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00436-016-5368-8
更新日期：2017-04-01 00:00:00
abstract：:Cabbage butterfly (Pieris rapae), included in the Lepidoptera genus, Pieris family, is the main pest that damages Cruciferae. In this paper, we reported a microsporidian isolate of Nosema species which was isolated from P. rapae in Zhenjiang City, Jiangsu Province, China. The mature spore of this microsporidium is lon...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-012-2829-6
更新日期：2012-07-01 00:00:00
abstract：:The parasite community structure of the neotropical cormorant, Phalacrocorax brasilianus, from two lagoons (Coyuca and Tres Palos) from Guerrero state, México, was examined. Fourteen species of adult helminths (6,391 individuals) from 48 cormorants were identified: 9 digeneans, 1 acanthocephalan, 1 cestode, and 3 nema...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2377-5
更新日期：2011-11-01 00:00:00
abstract：:Production of parasite-specific antibodies is an important component of immunity to blood stage malaria infection, as shown by several previous studies in rodent models. However, no study has addressed the induction of humoral immunity by different parasites in a genetically homogeneous host population. Here, levels o...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-002-0687-3
更新日期：2003-01-01 00:00:00
abstract：:Gametocyte proteins are being explored as potential vaccine candidates against Eimeria sp. in chicken since they are the components of the resilient oocyst wall. The aim of this study was to investigate the immunoprophylactic efficacy of recombinant Eimeria tenella gametocyte antigen 22 (EtGam22) in chickens against h...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-06198-2
更新日期：2019-03-01 00:00:00
abstract：:We examine the taxonomic composition and endemism of adult helminth parasites of freshwater fishes of Mexico, with regard to the main hydrological basins of the country. A presence-absence matrix, including every species of adult helminth parasites of freshwater fishes from 23 Mexican hydrological basins was compiled ...
journal_title：Parasitology research
pub_type： 杂志文章,评审
doi：10.1007/s00436-012-3175-4
更新日期：2013-01-01 00:00:00
abstract：:The artemisinin-based combination therapy (ACT) is adopted by several countries as first line for malaria treatment in the last decade. Concomitantly, the World Health Organization and other research reports showed a dramatic decline in malaria burden in terms of morbidity, mortality and treatment failure (TF). The op...
journal_title：Parasitology research
pub_type： 杂志文章,评审
doi：10.1007/s00436-009-1700-x
更新日期：2010-02-01 00:00:00
abstract：:Sheep infected with the triclabendazole-susceptible Cullompton isolate of Fasciola hepatica were dosed with 15 mg/kg of compound alpha at 12 weeks post-infection. Adult flukes were recovered from the bile ducts at 24, 48, and 72 h post-treatment (p.t.). Changes to the spermatogenic cells in the testis were examined by...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-009-1649-9
更新日期：2010-01-01 00:00:00
abstract：:Parasite-mediated selection is currently believed to play an important role in life-history evolution. To assess how simple hematoserological and biochemical condition indices reflect host immunocompetence and infection resistance controlled laboratory experiments are required. We addressed these issues by infecting l...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-006-0142-y
更新日期：2006-04-01 00:00:00
abstract：:Hepatozoon canis is a hemoprotozoan organism that infects domestic and wild carnivores throughout much of Europe. The parasite is mainly transmitted through the ingestion of infected ticks containing mature oocysts. The aims of the present survey were to determine the prevalence of H. canis in hunting dogs living in S...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06820-2
更新日期：2020-09-01 00:00:00
abstract：:The proboscis apex of the eoacanthocephalan parasite Paratenuisentis ambiguus was studied, using electron and light microscopy, for a better understanding of the parasite's attachment at the intestinal wall of its definitive hosts (Anguilla rostrata and A. anguilla). The results suggest the presence of an epidermis co...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/pl00008583
更新日期：2001-04-01 00:00:00
abstract：:Ticks and tick-borne diseases (TBDs) continue to pose an insidious and ever-present threat to livestock and livelihoods across the globe. Two of the most significant TBDs of cattle in Africa are heartwater and babesioisis, caused by Ehrlichia ruminantium and Babesia bigemina respectively. Both pathogens are endemic in...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-019-06204-1
更新日期：2019-03-01 00:00:00
abstract：:Trichomoniasis is the interplay between the infecting parasite, Trichomonas vaginalis, and the host, on which the clinical presentation of the disease depends. Although the clinical spectrum varies from an asymptomatic state to mild, moderate or severe symptoms, the exact virulence markers of T. vaginalis have not bee...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-004-1155-z
更新日期：2004-09-01 00:00:00
abstract：:In patients infected with Trichuris trichiura, large eggs as well as more typical eggs were frequently found in the feces; these large eggs have been attributed to human infection by T. vulpis. To clarify whether the female worms laying the large eggs were T. trichiura or T. vulpis, we examined the morphology of adult...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00930964
更新日期：1989-01-01 00:00:00
abstract：:More than 30 species of coccidian parasites have been described in Chelonidae (tortoises and turtles). Eimeria spp. are apparently the most common coccidia in chelonians. Findings of Caryospora cheloniae, Isospora sp., and Mantonella sp. have also been published, but reports about systemic coccidiosis are rare. We des...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0781-7
更新日期：2008-02-01 00:00:00
abstract：:Increased gametocytemia in infections with resistant strains of Plasmodium species and their enhanced transmissibility are a matter of concern in planning and evaluating the impact of malaria control strategies. Various studies have determined weekly gametocyte carriage in response to antimalarial drugs in clinical tr...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-014-3789-9
更新日期：2014-04-01 00:00:00
abstract：:The taxonomy and classification of the family Opisthorchiidae have been revised by several authors with the exclusion or synonymization of some genera. The genus Hepatiarius Feizullaev, 1961 accommodated two species: Hepatiarius sudarikovi Feizullaev, 1961 and H. longissimus Linstow, 1883. Recently, some experts have ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-019-06227-8
更新日期：2019-03-01 00:00:00
abstract：:This study evaluated, for the first time, the genetic diversity of Toxoplasma gondii isolates from free-range chickens from the state of Paraíba, Northeast Brazil. Tissue samples from 33 chickens from properties in five municipalities of Paraíba (Esperança, Olho d'Água, Malta, Monteiro, and Patos) were bioassayed in m...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-017-5531-x
更新日期：2017-08-01 00:00:00
abstract：:We investigated patterns of helminth infection in two closely related rodents (social Rhabdomys pumilio occurring mainly in xeric habitats and solitary R. dilectus occurring mainly in mesic habitats) at 20 localities in different biomes of South Africa and asked if between-species differences were mainly caused by dif...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-017-5419-9
更新日期：2017-04-01 00:00:00
abstract：:Gray mullet (Mugilidae) occur in all seas and are farmed widely around the world, and thus, the risk of their parasites spreading through transport of aquaculture seed is a serious concern. Among others, gray mullets typically host a diversity of myxosporeans, a group in which spore morphometrics of genera has been co...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-6151-9
更新日期：2019-01-01 00:00:00
