Colony-forming ability of human ovarian carcinomas in the Courtenay soft agar assay.

abstract：BACKGROUND:Angiogenesis is involved in the development of cancer, promoting tumor growth, invasiveness and metastasis. Vascular endothelial growth factor (VEGF) is a potent angiogenic factor. The present case control study was carried out, to determine whether there is an association between the VEGF -2578C > A polymor...

journal_title：Anticancer research

authors： Park HM,Hong SH,Kim JW,Oh D,Hwang SG,An HJ,Kim UK,Kim NK

更新日期：2007-07-01 00:00:00

abstract：AIM:To assess outcomes in patients treated with first-line bevacizumab-containing therapy for human epidermal growth factor receptor (HER)2-negative metastatic breast cancer (mBC) at a single centre with a homogenous standard-of-care. PATIENTS AND METHODS:Information on patient and disease characteristics, efficacy, a...

journal_title：Anticancer research

authors： Dieras V,Pop S,Berger F,Dujaric ME,Beuzeboc P,Escalup L,Bidard FC,Cottu PH,LE Tourneau C,Piperno-Neumann S,Laurence V,Robain M,Asselain B,Pierga JY

更新日期：2017-03-01 00:00:00

abstract：AIM:Eudragit® E 100 (EE100) was used to improve the transfection efficiency of polyethylenimine (PEI). MATERIALS AND METHODS:Mobility of PEI-DNA complexes with and without EE100 were visualized by agarose gel electrophoresis and their transfection efficiencies were investigated in KB human oral carcinoma cells by flow...

journal_title：Anticancer research

authors： Kanthamneni N,Yung B,Lee RJ

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIM:The clinical significance of surgery for secondary small intestinal non-Hodgkin's lymphomas (NHL) remains unknown. This study aimed to investigate the efficacy of resection for both primary and secondary small intestinal NHL. PATIENTS AND METHODS:Twenty patients with small intestinal lymphoma who underw...

journal_title：Anticancer research

authors： Iida T,Nozawa H,Sonoda H,Toyama K,Kawai K,Hata K,Tanaka T,Nishikawa T,Sasaki K,Shuno Y,Kaneko M,Murono K,Emoto S,Ishii H,Kurokawa M,Ishihara S

更新日期：2020-04-01 00:00:00

abstract：:Keratinocytes originating from adult human hair follicles, the most convenient biopsy tissue, can be serially cultured using a combination of two techniques. Primary cultures are established using plucked scalp hair follicles and the bovine eye lens capsule as a growth substrate. Subsequently, cells from these culture...

journal_title：Anticancer research

authors： Weterings PJ,Roelofs HM,Jansen BA,Vermorken AJ

更新日期：1983-05-01 00:00:00

abstract：BACKGROUND/AIM:Chemotherapy-associated toxicity is one of the limiting factors regarding treatment efficacy, patient outcome and quality of life in this collective. Underweight or obese patients represent a major group in which the therapy seems to be more challenging. The aim of this analysis was to evaluate the impac...

journal_title：Anticancer research

authors： Grabowski JP,Richter R,Rittmeister H,Chekerov R,Woopen H,Sehouli J

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND/AIM:Anthracyclines have been proven able to reduce the activity of vinca alkaloids by induction of cell-cycle arrest. The present study aims at identifying the critical initiation steps of signal transduction which transduce the inhibitory effects on the cytotoxicity of vinca alkaloids. MATERIALS AND METHOD...

journal_title：Anticancer research

authors： Ehrhardt H,Pfeiffer S,Schrembs D,Wachter F,Grunert M,Jeremias I

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND/AIM:The impact of testosterone or obesity on the pathological grade of prostate cancer remains controversial. Therefore, in this study, we investigated the relationship of serum testosterone and body mass index (BMI) to Gleason score at biopsy. PATIENTS AND METHODS:This study included 128 Japanese patients ...

journal_title：Anticancer research

authors： Shiota M,Takeuchi A,Sugimoto M,Dejima T,Kashiwagi E,Kiyoshima K,Inokuchi J,Tatsugami K,Yokomizo A

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND/AIM:The presence of ascites in ovarian cancer patients is considered a negative prognostic factor. The underlying mechanisms are not clearly understood. MATERIALS AND METHODS:The amount of ascites was evaluated, preferably, using diffusion-weighted MRI at primary diagnosis in a retrospective cohort of 214 w...

journal_title：Anticancer research

authors： Coosemans AN,Baert T,D'Heygere V,Wouters R,DE Laet L,VAN Hoylandt A,Thirion G,Ceusters J,Laenen A,Vandecaveye V,Vergote I

更新日期：2019-11-01 00:00:00

abstract：:Adult lymphoblastic lymphoma (LBL) can be of T-cell or B-cell lineage. However, the clinical significance of immunophenotypes is largely unknown. We conducted a retrospective study to compare T-cell LBL with its B-cell counterpart. Between 1983 and 1995, 50 adult patients were diagnosed as LBL at National Taiwan Unive...

journal_title：Anticancer research

authors： Yeh KH,Cheng AL,Su IJ,Lin MT,Tien HF,Shen MC,Wang CH,Chen YC

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Heterodimer cooperation between ErbB receptors has limited clinical usefulness of receptor tyrosine kinase inhibitors (TKIs), erlotinib and gefitinib in the treatment of cancer. However, combination treatment of TKIs with gamma-tocotrienol targets multiple ErbB receptors and significantly inhibit +SA murine ...

journal_title：Anticancer research

authors： Bachawal SV,Wali VB,Sylvester PW

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:The heterogeneity in prostate cancer is the reason for the difficult diagnosis and prognosis of this tumor. In this study, we looked for a correlation between prostate specific antigen (PSA), tumor staging and DNA cytophotometry. MATERIALS AND METHODS:Twenty-two prostates (pT1-T4) from patients with prostat...

journal_title：Anticancer research

authors： Krause FS,Feil G,Bichler KH,Schrott KM,Akcetin ZY,Engehausen DG

更新日期：2005-05-01 00:00:00

abstract：:When mouse resident peritoneal macrophages were cultured with PSK (Krestin), a protein-bound polysaccharide extracted from Coriolus versicolor, they became enlarged and elongated and expressed higher NBT-reducing activity. PSK stimulated the production of differentiation-inducing factor and cytotoxic factor by the mou...

journal_title：Anticancer research

authors： Kurakata Y,Sakagami H,Sato A,Kikuchi K,Takeda M,Asano K,Sato T

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Trastuzumab is used for the adjuvant (postoperative) treatment of (HER2)-positive early breast cancer. The duration of treatment is set at one year. The goal of our study was to examine the effective duration of trastuzumab treatment in routine clinical practice. PATIENTS AND METHODS:We performed a retrospe...

journal_title：Anticancer research

authors： Montserrat M,Leveque D,Barthelemy P,Bergerat JP

更新日期：2012-10-01 00:00:00

abstract：:Arsenic trioxide (ATO) is an inorganic arsenic derivative that is very effective against acute promyelocytic leukemia. However, organic arsenic derivatives (OAD) have a more favorable toxicity profile than ATO. We herein characterized dipropil-S-glycerol arsenic (GMZ27), a novel OAD. GMZ27 had potent antiproliferative...

journal_title：Anticancer research

authors： Cheng X,Quintás-Cardama A,Golemovic M,Zingaro R,Gao MZ,Freireich EJ,Andreeff M,Kantarjian HM,Verstovsek S

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND/AIM:We evaluated the efficacy and safety of carbon-ion radiotherapy (CIRT) alone for Stage III non-small-cell lung cancer (NSCLC). PATIENTS AND METHODS:Data of 65 patients (median age=73 years) with Stage III NSCLC who underwent CIRT alone in the QST Hospital, Chiba, Japan, between 1997 and 2015 were retros...

journal_title：Anticancer research

authors： Anzai M,Yamamoto N,Hayashi K,Nakajima M,Nomoto A,Ogawa K,Tsuji H

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND/AIM:Neoplastic spindle cells (NSCs) are believed to play a role in cancer invasion and metastasis, as well as in poor prognosis. The clinicopathological characteristics and prognostic relevance of NSCs was investigated in gallbladder cancer. MATERIALS AND METHODS:Specimens were obtained from 62 patients wit...

journal_title：Anticancer research

authors： Midorikawa R,Hisaka T,Sakai H,Nomura Y,Goto Y,Sato T,Kawahara R,Ishikawa H,Fujita F,Yasunaga M,Tanigawa M,Naito Y,Akiba J,Yano H,Tanaka H,Akagi Y,Okuda K

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Malignant glioma is one of the most intractable diseases in the human body. Rho-kinase (ROCK) is overexpressed and has been proposed as the main cause for the refractoriness of the disease. Since efficacious treatment is required, this study investigated the effect of inhibition of ROCK isoforms. MATERIALS ...

journal_title：Anticancer research

authors： Inaba N,Ishizawa S,Kimura M,Fujioka K,Watanabe M,Shibasaki T,Manome Y

更新日期：2010-09-01 00:00:00

abstract：:Human papillomaviruses (HPV) and their role in carcinogenesis have been the subject of extensive investigation Specific types of HPV have been associated with cervical carcinoma HPV 16 and 18 are mainly associated with malignant progression and considered "high risk" viruses Using Southern blot analysis and in situ hy...

journal_title：Anticancer research

authors： Vassilandonopoulou G,Panotopoulou E,Fotiou S,Tserkezoglou A,Machera E,Kottaridis S

更新日期：1997-01-01 00:00:00

abstract：:The circadian rhythm-modulated delivery of anticancer drugs has been shown to reduce toxicity and improve anticancer efficacy. The aim of this phase I trial was to compare the feasibility and tolerability of carboplatin (CBDCA) administered at circadian-modulated or flat infusion rate in 24 patients with advanced canc...

journal_title：Anticancer research

authors： Natoli C,Salini V,Irtelli L,Martino MT,Garufi C,Grassadonia A,Fiorentino B,Iacobelli S

更新日期：1996-05-01 00:00:00

abstract：:The in vitro antioxidative activity of benzylideneascorbate (SBA) and the in vivo effect on adriamycin (ADR)-induced cardiotoxicity in a mouse model were investigated. The radical-scavenging activity of SBA was assayed in terms of reduction of chemiluminescence induced by O2-, generated in xanthine/xanthine oxidase an...

journal_title：Anticancer research

authors： Kojima S,Iizuka H,Yamaguchi H,Tanuma S,Kochi M,Ueno Y

更新日期：1994-09-01 00:00:00

abstract：:The influence of bovine serum albumin on estradiol-17 beta growth and responsiveness of human mammary cancer MCF-7 cells was studied and compared to that of dextran-coated charcoal-treated fetal calf serum and other bovine serum proteins. To reveal the protein factor role, a culture defined medium was used. It was com...

journal_title：Anticancer research

authors： Germain P,Harbrioux G

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND/AIM:Malignant tumors of the salivary glands are rare and heterogeneous, with more than 20 subtypes, and classified mainly by histopathology. Their diagnosis is often challenging and their etiology unknown. Here, the possible association between human polyomaviruses (PyVs) and one or more salivary gland tumor...

journal_title：Anticancer research

authors： Ramqvist T,Ursu RG,Haeggblom L,Mirzaie L,Gahm C,Hammarstedt-Nordenvall L,Dalianis T,Näsman A

更新日期：2018-05-01 00:00:00

abstract：:The belief that n-3 polyunsaturated fatty acids are in general cytotoxic to tumor cells appears not to be accurate. Of four tumor cell lines exposed to 35 microM docosahexaenoic acid (DHA, 22:6 n-3), we found only one (A-427, lung carcinoma) to be sensitive, whereas three (A-172, A549 and SK-LU-1) in fact were stimula...

journal_title：Anticancer research

authors： Schønberg SA,Skorpen F

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND/AIM:There is no definite consensus regarding management of hepatocellular carcinoma (HCC) with portal vein tumor thrombosis (PVTT). This study aimed to compare clinical outcomes according to initial treatment modality for treatment of naïve HCC combined with subsegmental (Vp1)/ segmental (Vp2) PVTT with live...

journal_title：Anticancer research

authors： Yu JI,Choi GS,Lim DH,Lee E,Joh JW,Kwon CHD,Kim JM,Kim S,Woo SY,Paik SW,Park HC

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:S100(+) dendritic cells and CD57(+) lymphocytes are factors reflecting the immune system's ability to suppress the progress of tumor growth. CD57(+) cells include natural killer cells and late stages of T-effector lymphocytes. We evaluated the relationship between the known clinical and histological factors ...

journal_title：Anticancer research

authors： Liska V,Vycital O,Daum O,Novak P,Treska V,Bruha J,Pitule P,Holubec L

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND/AIM:Muscle relaxants, also known as neuromuscular blocking agents, can block nerve impulses to the muscles and are always used in surgery for general anesthesia. However, the effect of muscle-relaxant anesthetics on cell activity in gastric cancer is currently unknown. The present study aimed to examine and ...

journal_title：Anticancer research

authors： Jiang A,Zhao H,Liu X,Yu M,Chen J,Jiang WG

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the existence of an association between cervicovaginal infections and precancerous lesions of the uterine cervix, through determination of prevalent cervicovaginal micro-organisms, alone and in association with human papillomavirus (HPV), in patients with abnormal and normal vaginal cytology. PAT...

journal_title：Anticancer research

authors： Lukic A,Canzio C,Patella A,Giovagnoli M,Cipriani P,Frega A,Moscarini M

更新日期：2006-11-01 00:00:00

abstract：:Several human and murine tumor cell lines were evaluated in an in vitro cytotoxicity assay as prescreens for fermentation extracts and pure materials subsequently tested in vivo against P388 leukemia or B16 melanoma. Each material, regardless of its in vitro cytotoxicity, was evaluated in vivo. At the criteria levels ...

journal_title：Anticancer research

authors： Rose WC,Schurig JE,Meeker JB

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND/AIM:Amentoflavone has been shown to be effective against a variety of cancer cells, but its role in bladder cancer remains unclear. Thus, the aim of this study is to evaluate whether amentoflavone may induce toxicity effect of bladder cancer. MATERIALS AND METHODS:Herein, we evaluated amentoflavone effects ...

journal_title：Anticancer research

authors： Chiang CH,Yeh CY,Chung JG,Chiang IT,Hsu FT

更新日期：2019-07-01 00:00:00